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The map label for this gene is ttuB [H]

Identifier: 170751219

GI number: 170751219

Start: 5166447

End: 5167805

Strand: Direct

Name: ttuB [H]

Synonym: Mrad2831_4836

Alternate gene names: 170751219

Gene position: 5166447-5167805 (Clockwise)

Preceding gene: 170751218

Following gene: 170751223

Centisome position: 85.0

GC content: 72.26

Gene sequence:

>1359_bases
ATGGCAACACCGACCACGCCACACGCGGCGGACGCGGCCGCCTTCGAGAGCCGAACGATGCGGAAGGTCGGCCTGCGCCT
GATCCCCTTCCTCGTGCTCTGCTACTTCATCGCCTACGTCGACCGGGTGAATGTCGGCTTCGCGGCGCTGACCATGAACC
ACGATCTGGGTCTCTCCGCCGCGGCCTTCGGCCTGGGCGGCGGCCTGTTCTTCGTCGCCTACGTCCTGTTCGAGGTGCCG
AGCAACCTCGCGATGGAGCGCGTCGGCGCGCGGATCTGGATCGCGCGGATCATGATCACCTGGGGGCTCGTCGGCATCGG
CTCGGCCTTCGTCACCGGTCCGGTCAGCTTCGCCACCGCCCGCTTCCTGCTGGGCGCGGCCGAGGCCGGGTTCTTCCCGG
GCGTGATCCTGTACCTGACCTACTGGTTCCCCAAGGCCTACCGGGCGCGGATCGTGGCGATGTTCATGGTCGCGATCCCG
CTCTCCAGCTTCTTCGGCTCGCCGCTCTCGGCGGCGCTGCTCACCCTGGACGGCGCCGCGTCCCTGCGCGGCTGGCAGTG
GCTGCTGATCATGGAGGCGGTCCCGGCCGTCCTGCTCGGCGTCGCCGCCCTCGCGCTGCTGCCGAGCCGGCCGGCCGAGG
CGACCTTCCTGAGCCCGGCGGAGCGCGGCTGGCTGACGGACCGGCTGGAGGCCGAGCGGCGCGCCGCCGAGGCGGGCGCC
GGGCACCACGCCCACGGCCTCGCGGCGGTCTGGGCGGTGCTCGCGAGCCGGCAGGTCTGGCTGCTGGCCGTGATCTACGC
GGGCAGCTCGGCCACCAGCAACACGCTGTCGCTGTGGATGCCGCAGATCCTCAAGGGGTTCGGCCTCAGCAACCTGCAGA
CCGGCCTGCTGAACATGATCCCGTTCGGCATCGCCTCGGTCTTCATGATCGTCTGGGGCCTGCGGGCGGACCGCAGCGGC
GAGCGGATCTGGAGCACGGCCCTGCCGCTGGCGCTGACCTCGGTGAGCTTCGCCCTGACGCTGCTGACCGGCTCGCTCTG
GATGACGCTGGTCCTGCTCTCGCTGGTCCTGCTCGGCAACTACGCGATCAAGGGCCCGTTCTTCGCCCTGGCGACCGAGA
CGCTGCCGCCGGCCCAGACGGCCGCCGGCATCGCGGCGATCAACACCCTGGCGCATCTCGGCACCGGGGCGATCACCTCG
CTGATCGGGGTGCTGCGCGAGCAGACCGGCAGCTTCCCCGTCGCCCTGCTCCCGCTCTGCGCCCTCACCGGCGCCGGCTG
CGCCCTGGTCTTCTGGATCGGCCGGCACCGGCCGCGGGCAGCGGCCGTCGGGGCGGCCCCGTCGGCGGCGCGGGGCTGA

Upstream 100 bases:

>100_bases
GCCGAGCGCCGGATCGTCCTGGCCGAGACGCCCGCCGAACTCTTCCGCTTCGACCGCTAGGCCGGGGCGCGCCCGCCCGA
ATTCCAGCGAGGACAGGACC

Downstream 100 bases:

>100_bases
CGCGGCGGCGACGCTCAGGCCGGCTGGCCGAGGATTCCCAGGATCTCCCGGCGCAGCCGCACGATCTCGGGATCGTCGCG
GTGGCGCGGATAGGGCACCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MATPTTPHAADAAAFESRTMRKVGLRLIPFLVLCYFIAYVDRVNVGFAALTMNHDLGLSAAAFGLGGGLFFVAYVLFEVP
SNLAMERVGARIWIARIMITWGLVGIGSAFVTGPVSFATARFLLGAAEAGFFPGVILYLTYWFPKAYRARIVAMFMVAIP
LSSFFGSPLSAALLTLDGAASLRGWQWLLIMEAVPAVLLGVAALALLPSRPAEATFLSPAERGWLTDRLEAERRAAEAGA
GHHAHGLAAVWAVLASRQVWLLAVIYAGSSATSNTLSLWMPQILKGFGLSNLQTGLLNMIPFGIASVFMIVWGLRADRSG
ERIWSTALPLALTSVSFALTLLTGSLWMTLVLLSLVLLGNYAIKGPFFALATETLPPAQTAAGIAAINTLAHLGTGAITS
LIGVLREQTGSFPVALLPLCALTGAGCALVFWIGRHRPRAAAVGAAPSAARG

Sequences:

>Translated_452_residues
MATPTTPHAADAAAFESRTMRKVGLRLIPFLVLCYFIAYVDRVNVGFAALTMNHDLGLSAAAFGLGGGLFFVAYVLFEVP
SNLAMERVGARIWIARIMITWGLVGIGSAFVTGPVSFATARFLLGAAEAGFFPGVILYLTYWFPKAYRARIVAMFMVAIP
LSSFFGSPLSAALLTLDGAASLRGWQWLLIMEAVPAVLLGVAALALLPSRPAEATFLSPAERGWLTDRLEAERRAAEAGA
GHHAHGLAAVWAVLASRQVWLLAVIYAGSSATSNTLSLWMPQILKGFGLSNLQTGLLNMIPFGIASVFMIVWGLRADRSG
ERIWSTALPLALTSVSFALTLLTGSLWMTLVLLSLVLLGNYAIKGPFFALATETLPPAQTAAGIAAINTLAHLGTGAITS
LIGVLREQTGSFPVALLPLCALTGAGCALVFWIGRHRPRAAAVGAAPSAARG
>Mature_451_residues
ATPTTPHAADAAAFESRTMRKVGLRLIPFLVLCYFIAYVDRVNVGFAALTMNHDLGLSAAAFGLGGGLFFVAYVLFEVPS
NLAMERVGARIWIARIMITWGLVGIGSAFVTGPVSFATARFLLGAAEAGFFPGVILYLTYWFPKAYRARIVAMFMVAIPL
SSFFGSPLSAALLTLDGAASLRGWQWLLIMEAVPAVLLGVAALALLPSRPAEATFLSPAERGWLTDRLEAERRAAEAGAG
HHAHGLAAVWAVLASRQVWLLAVIYAGSSATSNTLSLWMPQILKGFGLSNLQTGLLNMIPFGIASVFMIVWGLRADRSGE
RIWSTALPLALTSVSFALTLLTGSLWMTLVLLSLVLLGNYAIKGPFFALATETLPPAQTAAGIAAINTLAHLGTGAITSL
IGVLREQTGSFPVALLPLCALTGAGCALVFWIGRHRPRAAAVGAAPSAARG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=426, Percent_Identity=33.5680751173709, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI2367379, Length=312, Percent_Identity=24.3589743589744, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082320, Length=286, Percent_Identity=25.1748251748252, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=329, Percent_Identity=26.1398176291793, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322025, Length=294, Percent_Identity=24.4897959183673, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319876, Length=298, Percent_Identity=23.8255033557047, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319250, Length=353, Percent_Identity=22.0963172804533, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322612, Length=289, Percent_Identity=22.4913494809689, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=135, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=294, Percent_Identity=21.4285714285714, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47683; Mature: 47552

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPTTPHAADAAAFESRTMRKVGLRLIPFLVLCYFIAYVDRVNVGFAALTMNHDLGLSA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
AAFGLGGGLFFVAYVLFEVPSNLAMERVGARIWIARIMITWGLVGIGSAFVTGPVSFATA
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHH
RFLLGAAEAGFFPGVILYLTYWFPKAYRARIVAMFMVAIPLSSFFGSPLSAALLTLDGAA
HHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
SLRGWQWLLIMEAVPAVLLGVAALALLPSRPAEATFLSPAERGWLTDRLEAERRAAEAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC
GHHAHGLAAVWAVLASRQVWLLAVIYAGSSATSNTLSLWMPQILKGFGLSNLQTGLLNMI
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
PFGIASVFMIVWGLRADRSGERIWSTALPLALTSVSFALTLLTGSLWMTLVLLSLVLLGN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAIKGPFFALATETLPPAQTAAGIAAINTLAHLGTGAITSLIGVLREQTGSFPVALLPLC
CHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHH
ALTGAGCALVFWIGRHRPRAAAVGAAPSAARG
HHCCCCHHHHHHHHCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
ATPTTPHAADAAAFESRTMRKVGLRLIPFLVLCYFIAYVDRVNVGFAALTMNHDLGLSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
AAFGLGGGLFFVAYVLFEVPSNLAMERVGARIWIARIMITWGLVGIGSAFVTGPVSFATA
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHH
RFLLGAAEAGFFPGVILYLTYWFPKAYRARIVAMFMVAIPLSSFFGSPLSAALLTLDGAA
HHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
SLRGWQWLLIMEAVPAVLLGVAALALLPSRPAEATFLSPAERGWLTDRLEAERRAAEAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCC
GHHAHGLAAVWAVLASRQVWLLAVIYAGSSATSNTLSLWMPQILKGFGLSNLQTGLLNMI
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
PFGIASVFMIVWGLRADRSGERIWSTALPLALTSVSFALTLLTGSLWMTLVLLSLVLLGN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAIKGPFFALATETLPPAQTAAGIAAINTLAHLGTGAITSLIGVLREQTGSFPVALLPLC
CHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHH
ALTGAGCALVFWIGRHRPRAAAVGAAPSAARG
HHCCCCHHHHHHHHCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]