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The map label for this gene is gstA [H]

Identifier: 170751075

GI number: 170751075

Start: 4992594

End: 4993211

Strand: Reverse

Name: gstA [H]

Synonym: Mrad2831_4686

Alternate gene names: 170751075

Gene position: 4993211-4992594 (Counterclockwise)

Preceding gene: 170751076

Following gene: 170751074

Centisome position: 82.15

GC content: 70.39

Gene sequence:

>618_bases
ATGAAGCTCTACCACCACCCCCTCTCGGGCCACGCGCATCGGGCGCGGCTGTTCCTCTCGTTGCTCGGCGTGCCGCACGA
GGCGATCGAGGTCGACCTCAAGGCAGGCGCCCACAAGCGGCCCGAGTTCCTTGCCCTCAATCCGTTCGGCCAGGTGCCGG
TCCTCGACGACGACGGAACCGTCGTCTCCGACTCGAACGCCATCCTCGTCTACGTGGCGCGCAAGCTGGGGCGGACCGAT
TGGCTGCCGGAGGATGCCGAGGGTGAGGCCGCCGTGCAGCGCTGGTTGTCGGTGGCAGCGGGCGAGCTCGCATACGGCCC
GGCGGCCGCGCGTCTCGTCACCGTGTTCGGCGCCAAGTTCAACCCGGAGGAGGTGATCGGCCGGGCGCACACGCTGCTCG
GTCGCCTGGAGGCCCATCTCACGGGGCGTGACTGGTTGGTCGGCGAGCGCCCCACCATCGCGGACGTCGCGCTCTACAGC
TACCTGGCGCGCGCCCCGGAGGGCAACGTCGACCTCTCCGGCTATCCCACCGTCAACGCGTACCTTCGCCGGATCGAGGC
CCTGCCGGGCTTCGTCTCGTTCGTCCAAACGCCGGCAGGCCTCACGGCCGCCGCGTGA

Upstream 100 bases:

>100_bases
CAATGAACTGCGGAGGTCGAGCATTCTCCCGACCCCCTGATCGCGTCACCTTGCCAATGTGGTTCGGGCTTCACCCGGAC
AGAAAGCAGGGAACGCGGTC

Downstream 100 bases:

>100_bases
CCTCGCTGGTCCGGGCGCACCTCTGGGTGCGCCCGACCGGAATGGATGGGAGAGCACCATGAGCGACGGTACGACGATGA
CGAAGCTCTCGACCTGGCAC

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKLYHHPLSGHAHRARLFLSLLGVPHEAIEVDLKAGAHKRPEFLALNPFGQVPVLDDDGTVVSDSNAILVYVARKLGRTD
WLPEDAEGEAAVQRWLSVAAGELAYGPAAARLVTVFGAKFNPEEVIGRAHTLLGRLEAHLTGRDWLVGERPTIADVALYS
YLARAPEGNVDLSGYPTVNAYLRRIEALPGFVSFVQTPAGLTAAA

Sequences:

>Translated_205_residues
MKLYHHPLSGHAHRARLFLSLLGVPHEAIEVDLKAGAHKRPEFLALNPFGQVPVLDDDGTVVSDSNAILVYVARKLGRTD
WLPEDAEGEAAVQRWLSVAAGELAYGPAAARLVTVFGAKFNPEEVIGRAHTLLGRLEAHLTGRDWLVGERPTIADVALYS
YLARAPEGNVDLSGYPTVNAYLRRIEALPGFVSFVQTPAGLTAAA
>Mature_205_residues
MKLYHHPLSGHAHRARLFLSLLGVPHEAIEVDLKAGAHKRPEFLALNPFGQVPVLDDDGTVVSDSNAILVYVARKLGRTD
WLPEDAEGEAAVQRWLSVAAGELAYGPAAARLVTVFGAKFNPEEVIGRAHTLLGRLEAHLTGRDWLVGERPTIADVALYS
YLARAPEGNVDLSGYPTVNAYLRRIEALPGFVSFVQTPAGLTAAA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=200, Percent_Identity=30.5, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI124249394, Length=200, Percent_Identity=30.5, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=28.921568627451, Blast_Score=71, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922526, Length=200, Percent_Identity=33, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20130115, Length=180, Percent_Identity=32.7777777777778, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654992, Length=181, Percent_Identity=33.7016574585635, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17933730, Length=187, Percent_Identity=26.7379679144385, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922532, Length=181, Percent_Identity=33.1491712707182, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI20130123, Length=196, Percent_Identity=33.1632653061224, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17864592, Length=183, Percent_Identity=28.9617486338798, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864594, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI85725204, Length=191, Percent_Identity=28.2722513089005, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737923, Length=191, Percent_Identity=28.2722513089005, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24654983, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24654996, Length=184, Percent_Identity=32.0652173913043, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571670, Length=173, Percent_Identity=27.7456647398844, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654965, Length=183, Percent_Identity=31.1475409836066, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221378141, Length=186, Percent_Identity=31.1827956989247, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922528, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17864596, Length=193, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654975, Length=167, Percent_Identity=31.7365269461078, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45549270, Length=180, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI62472445, Length=186, Percent_Identity=31.1827956989247, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654979, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646259, Length=186, Percent_Identity=28.494623655914, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221378983, Length=186, Percent_Identity=28.494623655914, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22122; Mature: 22122

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYHHPLSGHAHRARLFLSLLGVPHEAIEVDLKAGAHKRPEFLALNPFGQVPVLDDDGT
CCCCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCEEEECCCCCCEEECCCCC
VVSDSNAILVYVARKLGRTDWLPEDAEGEAAVQRWLSVAAGELAYGPAAARLVTVFGAKF
EEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCC
NPEEVIGRAHTLLGRLEAHLTGRDWLVGERPTIADVALYSYLARAPEGNVDLSGYPTVNA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
YLRRIEALPGFVSFVQTPAGLTAAA
HHHHHHHCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLYHHPLSGHAHRARLFLSLLGVPHEAIEVDLKAGAHKRPEFLALNPFGQVPVLDDDGT
CCCCCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCEEEECCCCCCEEECCCCC
VVSDSNAILVYVARKLGRTDWLPEDAEGEAAVQRWLSVAAGELAYGPAAARLVTVFGAKF
EEECCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCC
NPEEVIGRAHTLLGRLEAHLTGRDWLVGERPTIADVALYSYLARAPEGNVDLSGYPTVNA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
YLRRIEALPGFVSFVQTPAGLTAAA
HHHHHHHCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA