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The map label for this gene is tlpA [H]

Identifier: 170750892

GI number: 170750892

Start: 4785567

End: 4786208

Strand: Reverse

Name: tlpA [H]

Synonym: Mrad2831_4503

Alternate gene names: 170750892

Gene position: 4786208-4785567 (Counterclockwise)

Preceding gene: 170750897

Following gene: 170750891

Centisome position: 78.75

GC content: 74.45

Gene sequence:

>642_bases
ATGCCCGGCCGCACACCCATCCTGGCCGGCGCGGGCGTCGCCGCGCTCGCCGTCCTCGGGCTCGCCCTATACGGGAGCGG
TCTCCTGCCCGGCAACACGGGCGGCGCCCTCCAGCCCTGCGCCGCCGCCAAGCCGGCTTTGGCCCGGGTCGATGCGGCGT
CCAAGGGCGAGGTCGCCGCCATGCAGGCGCTGCCCCAGGCCCGGCCCGCCCCCGAAATCCGGTTCAAGGGCCCGGACGGC
GCCGAGACCGGCCTCGCCGACCTCAAGGGCCGGCTGCTCCTCGTCAATCTCTGGGCGACGTGGTGCGCGCCCTGCAAGGC
CGAGATGCCCGCCCTCGACCGGCTCCAGGCGCAGCTCGGCGGACCCGACTTCCAGGTCGTCGCCATCAACGTCGACACGC
GCAACCTCGAGAAGCCGCCGGAATGGCTGAAGCAGGCGGGCATCCACGACCTCGCCTACTACGCCGATCCCGGCGGCCGC
GTGCTGCCGATCCTCCAGCGCGACACGCAGTCGCCCGGCCTGCCGACCACGATGCTGGTCGACGCGCAGGGCTGCACGAT
CGGGGTGATGAAGGGGCCGGCCGCGTGGTCGAGCCCGGACGGGCTGGCGCTGATCCGCGCTGCCCTGGGGCGGACGTCGT
AG

Upstream 100 bases:

>100_bases
CCTCCATGATCTCCGCCGGGCCGCTCGCGAAGCGGCCGCCCCACATCCGGTTGCTCATGTCGATCCTTCCGCGCCCTGAA
CGCCCCGGCAGGCAAAGCTG

Downstream 100 bases:

>100_bases
GGCTTCGAGCGGGACTTCGGCCAGTCGCTTGCGCGTCCCCGCGATGCGCGGCAAGGCCTGCCGCGATGACGTCGCCCACC
CCCGACAGCCCCCCGCCGCG

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPGRTPILAGAGVAALAVLGLALYGSGLLPGNTGGALQPCAAAKPALARVDAASKGEVAAMQALPQARPAPEIRFKGPDG
AETGLADLKGRLLLVNLWATWCAPCKAEMPALDRLQAQLGGPDFQVVAINVDTRNLEKPPEWLKQAGIHDLAYYADPGGR
VLPILQRDTQSPGLPTTMLVDAQGCTIGVMKGPAAWSSPDGLALIRAALGRTS

Sequences:

>Translated_213_residues
MPGRTPILAGAGVAALAVLGLALYGSGLLPGNTGGALQPCAAAKPALARVDAASKGEVAAMQALPQARPAPEIRFKGPDG
AETGLADLKGRLLLVNLWATWCAPCKAEMPALDRLQAQLGGPDFQVVAINVDTRNLEKPPEWLKQAGIHDLAYYADPGGR
VLPILQRDTQSPGLPTTMLVDAQGCTIGVMKGPAAWSSPDGLALIRAALGRTS
>Mature_212_residues
PGRTPILAGAGVAALAVLGLALYGSGLLPGNTGGALQPCAAAKPALARVDAASKGEVAAMQALPQARPAPEIRFKGPDGA
ETGLADLKGRLLLVNLWATWCAPCKAEMPALDRLQAQLGGPDFQVVAINVDTRNLEKPPEWLKQAGIHDLAYYADPGGRV
LPILQRDTQSPGLPTTMLVDAQGCTIGVMKGPAAWSSPDGLALIRAALGRTS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21900; Mature: 21768

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRTPILAGAGVAALAVLGLALYGSGLLPGNTGGALQPCAAAKPALARVDAASKGEVAA
CCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHCCCCCCCCHHH
MQALPQARPAPEIRFKGPDGAETGLADLKGRLLLVNLWATWCAPCKAEMPALDRLQAQLG
HHHCCCCCCCCCEEECCCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHC
GPDFQVVAINVDTRNLEKPPEWLKQAGIHDLAYYADPGGRVLPILQRDTQSPGLPTTMLV
CCCEEEEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEE
DAQGCTIGVMKGPAAWSSPDGLALIRAALGRTS
ECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PGRTPILAGAGVAALAVLGLALYGSGLLPGNTGGALQPCAAAKPALARVDAASKGEVAA
CCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHHCCCCCCCCHHH
MQALPQARPAPEIRFKGPDGAETGLADLKGRLLLVNLWATWCAPCKAEMPALDRLQAQLG
HHHCCCCCCCCCEEECCCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHC
GPDFQVVAINVDTRNLEKPPEWLKQAGIHDLAYYADPGGRVLPILQRDTQSPGLPTTMLV
CCCEEEEEEEECCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEE
DAQGCTIGVMKGPAAWSSPDGLALIRAALGRTS
ECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]