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The map label for this gene is 170750884

Identifier: 170750884

GI number: 170750884

Start: 4775901

End: 4777616

Strand: Direct

Name: 170750884

Synonym: Mrad2831_4495

Alternate gene names: NA

Gene position: 4775901-4777616 (Clockwise)

Preceding gene: 170750883

Following gene: 170750886

Centisome position: 78.58

GC content: 73.95

Gene sequence:

>1716_bases
GTGAATGAGAGGGTGGGGCAGGACCCGGCGGCGGAGGACCCGTTTCGCGCCGGCTTCGACGAGGCCGCGATCGGCCTCGC
CGTGCTGTCGGCGGACGGGGCGGGGATCGTCGCCGCCAACCGCGCCCTGCACGATCTCGTCGGCTGGCCGCCGGGCACGC
TGTCCGGGCGCGCGGCCGCCGAACTCCTGAACGAGGGGCCCGACGGCCTCCGGGACGGTCTCCAGGTCTGGCGCCGGGCG
GACGGGGCACCCCTCGACGTGCGGGTCCGGCGCGCGGGCCGGACCCTGGTGGTCGAGGCGGTCGACGTGGACGCGGCGGC
CCATTCCGAGGCGAACCGCGAGGCCCTGGCGGCCGCCGGGCTCGGGGAATGGCGCTGGGACCGCGCGACCGGCCTCCTCA
CCCTGTCGCGCCGCGCCGCCCGCATCCTCGGGCGGCCGCCGGGCCGGTCCGTCTCGTGGGAGGAATTGAAGACGGGCCTG
TCGCAGGCGGAACTCGCGCGCCTGCGCGCGCTGATCGCCGAGGCGGACGGGACCGACGAGCCCTATCAGTTCGACACGGC
CACCACGGTGGCCGGGCGGACCGTGATCCTGCGGGTCCGGGGGCAGGCCGTGCCGGGCCCCGACGGCACGCCGGCCGGTA
TGGTCGGCATCCTCCAGGACATCACCACGCGGGTCGAGGCCCGGGACGAGATCCTGTCCCGCGACCAGCGCCTGCGGGTC
GCCACCACGGTCGCCCGGCTCGGCATCTTCGAGTGGCACATGCTCGAGGACCAGGCGATCTGGGAGAACGAGCACATGTA
CGAGATCTTCGGGCACGCGCCCGAGGACGGCACGATCGGCAAGAACGAGTTCCTCAACGACATCCTCCACCCCGACGACC
GCCCCGCCGTCCGCCGGGCGATCTCCCAGGCGCTGCGGGAGGACGGGGATCTGCACATCAGCGGCCGGATCCGCCGCAAG
TCCGACGGCGTGTGGCGCACGATCGACATGGCCGGCCGGTTCGAGCGCGACGCCCCCGGCCGCCTGCCCCGCCGCCTGAT
CGGCGTCGTCGCGGACGTGACCGACCGCCGGGTCGCGGAGGAGCGCCAGAGCCTGCTGATCCGCGAGCTCCACCACCGGG
TGAAGAACACGCTGGCCACGGTCCAGGCCATCGTGGGCTCCACCGCGCGGACGGCGTCGAGCATCGAGAGCTTCTACGAG
GCGTTCGTCGGGCGCATCAAATCCCTGGCGCACACGCACTCGGTCCTCACCGAGGACACGTGGCAGACGGCGTCGCTGGC
CAACCTCCTGCGCAACGAGCTGAAGCCCTACGCGGAGGTGGCGCCGGACGGCGGCGCCGAGGGCCGCATCAGCCTCGACG
GGCCGGCGATCGACCTGCCGTCCGAGATCGCGGTGCCGATCGGCATGGCGATCCACGAACTCACCACCAACGCGGCGAAG
TACGGGGCCCTGTCGAACCGCACCGGCCGGGTGGCGGTGGAATGGTCCCTGGAGCCCGGGGGGCCGGCCGGGATCCTGCG
GTTCTCATGGCGCGAGACCGGCGGCCCTCCGGTCGCGCCGCCGAGCCGCCAGGGCTTCGGCTCGCGCCTGCTGCAGCGCG
TCCTGATCACCCAGGTCCAGGCCGAGGTGACCACCGACTACGCCCCCGGGGGCTTCTCCCTGACCATGCGGGCCCCGATC
CCGCCGCGCAACGACAGCCTCAACCCGCTGGTGTGA

Upstream 100 bases:

>100_bases
CTCGGGCGCCATCCTCAGGGCCCGCCGCGGTCCCGGATCGTGGCGGGAGGGGGCCATCTCCGGCGGGAGCGTGCCACGGC
ACGTTCGAGGATTCTTCCGA

Downstream 100 bases:

>100_bases
GGCCGCGGCCGCCCTCAGGGCGGGTTCAGGCCGCGCCGCGGGTCCCGGACTCGCCGCCGCCGTCCACGAAGGCCTTCAGC
TCGTCGAGGGACGCGAAGGT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MNERVGQDPAAEDPFRAGFDEAAIGLAVLSADGAGIVAANRALHDLVGWPPGTLSGRAAAELLNEGPDGLRDGLQVWRRA
DGAPLDVRVRRAGRTLVVEAVDVDAAAHSEANREALAAAGLGEWRWDRATGLLTLSRRAARILGRPPGRSVSWEELKTGL
SQAELARLRALIAEADGTDEPYQFDTATTVAGRTVILRVRGQAVPGPDGTPAGMVGILQDITTRVEARDEILSRDQRLRV
ATTVARLGIFEWHMLEDQAIWENEHMYEIFGHAPEDGTIGKNEFLNDILHPDDRPAVRRAISQALREDGDLHISGRIRRK
SDGVWRTIDMAGRFERDAPGRLPRRLIGVVADVTDRRVAEERQSLLIRELHHRVKNTLATVQAIVGSTARTASSIESFYE
AFVGRIKSLAHTHSVLTEDTWQTASLANLLRNELKPYAEVAPDGGAEGRISLDGPAIDLPSEIAVPIGMAIHELTTNAAK
YGALSNRTGRVAVEWSLEPGGPAGILRFSWRETGGPPVAPPSRQGFGSRLLQRVLITQVQAEVTTDYAPGGFSLTMRAPI
PPRNDSLNPLV

Sequences:

>Translated_571_residues
MNERVGQDPAAEDPFRAGFDEAAIGLAVLSADGAGIVAANRALHDLVGWPPGTLSGRAAAELLNEGPDGLRDGLQVWRRA
DGAPLDVRVRRAGRTLVVEAVDVDAAAHSEANREALAAAGLGEWRWDRATGLLTLSRRAARILGRPPGRSVSWEELKTGL
SQAELARLRALIAEADGTDEPYQFDTATTVAGRTVILRVRGQAVPGPDGTPAGMVGILQDITTRVEARDEILSRDQRLRV
ATTVARLGIFEWHMLEDQAIWENEHMYEIFGHAPEDGTIGKNEFLNDILHPDDRPAVRRAISQALREDGDLHISGRIRRK
SDGVWRTIDMAGRFERDAPGRLPRRLIGVVADVTDRRVAEERQSLLIRELHHRVKNTLATVQAIVGSTARTASSIESFYE
AFVGRIKSLAHTHSVLTEDTWQTASLANLLRNELKPYAEVAPDGGAEGRISLDGPAIDLPSEIAVPIGMAIHELTTNAAK
YGALSNRTGRVAVEWSLEPGGPAGILRFSWRETGGPPVAPPSRQGFGSRLLQRVLITQVQAEVTTDYAPGGFSLTMRAPI
PPRNDSLNPLV
>Mature_571_residues
MNERVGQDPAAEDPFRAGFDEAAIGLAVLSADGAGIVAANRALHDLVGWPPGTLSGRAAAELLNEGPDGLRDGLQVWRRA
DGAPLDVRVRRAGRTLVVEAVDVDAAAHSEANREALAAAGLGEWRWDRATGLLTLSRRAARILGRPPGRSVSWEELKTGL
SQAELARLRALIAEADGTDEPYQFDTATTVAGRTVILRVRGQAVPGPDGTPAGMVGILQDITTRVEARDEILSRDQRLRV
ATTVARLGIFEWHMLEDQAIWENEHMYEIFGHAPEDGTIGKNEFLNDILHPDDRPAVRRAISQALREDGDLHISGRIRRK
SDGVWRTIDMAGRFERDAPGRLPRRLIGVVADVTDRRVAEERQSLLIRELHHRVKNTLATVQAIVGSTARTASSIESFYE
AFVGRIKSLAHTHSVLTEDTWQTASLANLLRNELKPYAEVAPDGGAEGRISLDGPAIDLPSEIAVPIGMAIHELTTNAAK
YGALSNRTGRVAVEWSLEPGGPAGILRFSWRETGGPPVAPPSRQGFGSRLLQRVLITQVQAEVTTDYAPGGFSLTMRAPI
PPRNDSLNPLV

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61919; Mature: 61919

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERVGQDPAAEDPFRAGFDEAAIGLAVLSADGAGIVAANRALHDLVGWPPGTLSGRAAA
CCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCHHHHH
ELLNEGPDGLRDGLQVWRRADGAPLDVRVRRAGRTLVVEAVDVDAAAHSEANREALAAAG
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCHHHCCCHHHHHHHHCC
LGEWRWDRATGLLTLSRRAARILGRPPGRSVSWEELKTGLSQAELARLRALIAEADGTDE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCC
PYQFDTATTVAGRTVILRVRGQAVPGPDGTPAGMVGILQDITTRVEARDEILSRDQRLRV
CEECCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATTVARLGIFEWHMLEDQAIWENEHMYEIFGHAPEDGTIGKNEFLNDILHPDDRPAVRRA
HHHHHHHHHHHEEEECCCHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHH
ISQALREDGDLHISGRIRRKSDGVWRTIDMAGRFERDAPGRLPRRLIGVVADVTDRRVAE
HHHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERQSLLIRELHHRVKNTLATVQAIVGSTARTASSIESFYEAFVGRIKSLAHTHSVLTEDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQTASLANLLRNELKPYAEVAPDGGAEGRISLDGPAIDLPSEIAVPIGMAIHELTTNAAK
CHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
YGALSNRTGRVAVEWSLEPGGPAGILRFSWRETGGPPVAPPSRQGFGSRLLQRVLITQVQ
HCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AEVTTDYAPGGFSLTMRAPIPPRNDSLNPLV
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNERVGQDPAAEDPFRAGFDEAAIGLAVLSADGAGIVAANRALHDLVGWPPGTLSGRAAA
CCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCHHHHH
ELLNEGPDGLRDGLQVWRRADGAPLDVRVRRAGRTLVVEAVDVDAAAHSEANREALAAAG
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCHHHCCCHHHHHHHHCC
LGEWRWDRATGLLTLSRRAARILGRPPGRSVSWEELKTGLSQAELARLRALIAEADGTDE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCC
PYQFDTATTVAGRTVILRVRGQAVPGPDGTPAGMVGILQDITTRVEARDEILSRDQRLRV
CEECCCHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATTVARLGIFEWHMLEDQAIWENEHMYEIFGHAPEDGTIGKNEFLNDILHPDDRPAVRRA
HHHHHHHHHHHEEEECCCHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHHH
ISQALREDGDLHISGRIRRKSDGVWRTIDMAGRFERDAPGRLPRRLIGVVADVTDRRVAE
HHHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERQSLLIRELHHRVKNTLATVQAIVGSTARTASSIESFYEAFVGRIKSLAHTHSVLTEDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQTASLANLLRNELKPYAEVAPDGGAEGRISLDGPAIDLPSEIAVPIGMAIHELTTNAAK
CHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
YGALSNRTGRVAVEWSLEPGGPAGILRFSWRETGGPPVAPPSRQGFGSRLLQRVLITQVQ
HCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AEVTTDYAPGGFSLTMRAPIPPRNDSLNPLV
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA