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The map label for this gene is ybdL [H]

Identifier: 170750710

GI number: 170750710

Start: 4576740

End: 4577969

Strand: Direct

Name: ybdL [H]

Synonym: Mrad2831_4321

Alternate gene names: 170750710

Gene position: 4576740-4577969 (Clockwise)

Preceding gene: 170750703

Following gene: 170750711

Centisome position: 75.3

GC content: 73.74

Gene sequence:

>1230_bases
ATGCTAAGGGCCGGCGATGCCGAGACCCGCCATGCCGACCTCCCCGATCCCCGGCGCCGCATGACGCCCGCCTTCATCAA
CCCCGTCTTCGACGCGCTGCCCACGACCGTGTTCGAGACCATGTCGCGGCTCGCGCGGGTCCACGGCGCGATCAATCTCG
GCCAGGGTTTCCCGGACGATCCCGGGCCGGCGGACGTCCGAGAGCGGGGCGCGCGGGCGCTCCTGGACGGCTGGAACCAG
TACCCGCCGATGATGGGCCTGCCGGCCCTGCGCGAGGCGGTCGCCGCGCACTACGCGCGGCACCAGGGGCTCGACCTCGA
CCCGGAGACCGAGGTGATGGTCACCTCCGGGGCGACCGAGGCCCTGGCCGGCGCGCTCCTGGCGCTGATCGAGCCCGGCG
ACGAGGTCGTGCTGTTCGCGCCCATGTACGATGCCTACCTGCCCCTGGTCCGGCGGGCGGGCGGCGTTCCGCGGATCGTG
CCGCTGCGGCCCCCGGCCTTCCGCCTCGACGAGGCCGCGCTGGCGCAGGCCTTTGGGGCGCGGACCCGGGTCGTGGTGCT
GAACAATCCCCTCAACCCGAGCGCCACGCTGTTCGCGCCGGAGGACCTCGACCTGCTCGCCCGCTACTGCCAGCGCTTCG
ACGTGACCGCCCTCTGCGACGAGGTCTGGGAGCACGTGGTGTTCGACGGCGCGCGCCACAGGCCGCTGATGGCGCTGCCC
GGGATGCGGGAGCGGACCGTCAAGATCGGCTCGGCCGGCAAGATCTTCTCGCTCACCGGCTGGAAGGTCGGCTTCGTGAT
GGCCGAGGCCCGGCTGATGCGCGGGCTCGCCAAGGCGCACCAGTTCCTGACCTTCACCACGCCCCCGAACCTCCAGGAGG
CGGTGGCCTACGGGCTGGGCAAGCCGGCCCCGTGGTTCGAGGCGATGCGGGCCGGCTACGCCCGGTCCCGCGACCGGCTC
GCGGACGGCCTGCGCGGGCTCGGCTTCACCGTGCTGCCGGCCCAGGCCACGTGGTTCCTCAACGTCGACGTCGCCGCGCT
GGGCCACACCGACGACGTGGCCTTCTGCGAGGCCCTCGTCACCCGTCACGGCGTCGCGGCGATCCCCGTGAGCGCCTTCT
ACCCGGACGCCTCCGTGCGCGGCCTCGTCCGGCTCTGCTTCGCCAAGGACGACGCCACCCTGGATGCGGCGCTCGACCGC
ATGCGCGGGCTCCCCGGGGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGCTGATGAATGTCAATATTCGTCAGCCGTCGGTCGCGCTTCGGCGACCGGGTCTGTGCGAAGGCGCACATTCCGCGACG
CGCGACGGCCCTGCGCGGCC

Downstream 100 bases:

>100_bases
GTGGCGCCATGGGAGGCGCCATGGGAGACGCCACGACGGGCGGCGCGCGCCGAGCGGGCGCCGTCCTTGCGGGGATCCGG
ACGGGGGGCCACATCGTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLRAGDAETRHADLPDPRRRMTPAFINPVFDALPTTVFETMSRLARVHGAINLGQGFPDDPGPADVRERGARALLDGWNQ
YPPMMGLPALREAVAAHYARHQGLDLDPETEVMVTSGATEALAGALLALIEPGDEVVLFAPMYDAYLPLVRRAGGVPRIV
PLRPPAFRLDEAALAQAFGARTRVVVLNNPLNPSATLFAPEDLDLLARYCQRFDVTALCDEVWEHVVFDGARHRPLMALP
GMRERTVKIGSAGKIFSLTGWKVGFVMAEARLMRGLAKAHQFLTFTTPPNLQEAVAYGLGKPAPWFEAMRAGYARSRDRL
ADGLRGLGFTVLPAQATWFLNVDVAALGHTDDVAFCEALVTRHGVAAIPVSAFYPDASVRGLVRLCFAKDDATLDAALDR
MRGLPGAAA

Sequences:

>Translated_409_residues
MLRAGDAETRHADLPDPRRRMTPAFINPVFDALPTTVFETMSRLARVHGAINLGQGFPDDPGPADVRERGARALLDGWNQ
YPPMMGLPALREAVAAHYARHQGLDLDPETEVMVTSGATEALAGALLALIEPGDEVVLFAPMYDAYLPLVRRAGGVPRIV
PLRPPAFRLDEAALAQAFGARTRVVVLNNPLNPSATLFAPEDLDLLARYCQRFDVTALCDEVWEHVVFDGARHRPLMALP
GMRERTVKIGSAGKIFSLTGWKVGFVMAEARLMRGLAKAHQFLTFTTPPNLQEAVAYGLGKPAPWFEAMRAGYARSRDRL
ADGLRGLGFTVLPAQATWFLNVDVAALGHTDDVAFCEALVTRHGVAAIPVSAFYPDASVRGLVRLCFAKDDATLDAALDR
MRGLPGAAA
>Mature_409_residues
MLRAGDAETRHADLPDPRRRMTPAFINPVFDALPTTVFETMSRLARVHGAINLGQGFPDDPGPADVRERGARALLDGWNQ
YPPMMGLPALREAVAAHYARHQGLDLDPETEVMVTSGATEALAGALLALIEPGDEVVLFAPMYDAYLPLVRRAGGVPRIV
PLRPPAFRLDEAALAQAFGARTRVVVLNNPLNPSATLFAPEDLDLLARYCQRFDVTALCDEVWEHVVFDGARHRPLMALP
GMRERTVKIGSAGKIFSLTGWKVGFVMAEARLMRGLAKAHQFLTFTTPPNLQEAVAYGLGKPAPWFEAMRAGYARSRDRL
ADGLRGLGFTVLPAQATWFLNVDVAALGHTDDVAFCEALVTRHGVAAIPVSAFYPDASVRGLVRLCFAKDDATLDAALDR
MRGLPGAAA

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=36.0406091370558, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=36.0406091370558, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI56713254, Length=415, Percent_Identity=33.2530120481928, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI56713256, Length=414, Percent_Identity=33.3333333333333, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI169881281, Length=392, Percent_Identity=31.6326530612245, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4507369, Length=337, Percent_Identity=24.9258160237389, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI149944424, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=43.2795698924731, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=28.042328042328, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788627, Length=196, Percent_Identity=22.9591836734694, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=403, Percent_Identity=34.4913151364764, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=34.4913151364764, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=30.9045226130653, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17567663, Length=348, Percent_Identity=21.551724137931, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=31.4285714285714, Blast_Score=195, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28573069, Length=397, Percent_Identity=34.5088161209068, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24646114, Length=397, Percent_Identity=34.5088161209068, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI28573067, Length=397, Percent_Identity=34.5088161209068, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI28573065, Length=397, Percent_Identity=34.5088161209068, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI18859735, Length=340, Percent_Identity=27.3529411764706, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44339; Mature: 44339

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRAGDAETRHADLPDPRRRMTPAFINPVFDALPTTVFETMSRLARVHGAINLGQGFPDD
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGPADVRERGARALLDGWNQYPPMMGLPALREAVAAHYARHQGLDLDPETEVMVTSGATE
CCCHHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
ALAGALLALIEPGDEVVLFAPMYDAYLPLVRRAGGVPRIVPLRPPAFRLDEAALAQAFGA
HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCC
RTRVVVLNNPLNPSATLFAPEDLDLLARYCQRFDVTALCDEVWEHVVFDGARHRPLMALP
CEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEECC
GMRERTVKIGSAGKIFSLTGWKVGFVMAEARLMRGLAKAHQFLTFTTPPNLQEAVAYGLG
CCCHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCC
KPAPWFEAMRAGYARSRDRLADGLRGLGFTVLPAQATWFLNVDVAALGHTDDVAFCEALV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEEEECCCCCHHHHHHHHH
TRHGVAAIPVSAFYPDASVRGLVRLCFAKDDATLDAALDRMRGLPGAAA
HHCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLRAGDAETRHADLPDPRRRMTPAFINPVFDALPTTVFETMSRLARVHGAINLGQGFPDD
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGPADVRERGARALLDGWNQYPPMMGLPALREAVAAHYARHQGLDLDPETEVMVTSGATE
CCCHHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
ALAGALLALIEPGDEVVLFAPMYDAYLPLVRRAGGVPRIVPLRPPAFRLDEAALAQAFGA
HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCC
RTRVVVLNNPLNPSATLFAPEDLDLLARYCQRFDVTALCDEVWEHVVFDGARHRPLMALP
CEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEECC
GMRERTVKIGSAGKIFSLTGWKVGFVMAEARLMRGLAKAHQFLTFTTPPNLQEAVAYGLG
CCCHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCC
KPAPWFEAMRAGYARSRDRLADGLRGLGFTVLPAQATWFLNVDVAALGHTDDVAFCEALV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEEEECCCCCHHHHHHHHH
TRHGVAAIPVSAFYPDASVRGLVRLCFAKDDATLDAALDRMRGLPGAAA
HHCCCEEEEHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]