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The map label for this gene is feaR [H]

Identifier: 170750621

GI number: 170750621

Start: 4481919

End: 4482974

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_4231

Alternate gene names: 170750621

Gene position: 4482974-4481919 (Counterclockwise)

Preceding gene: 170750624

Following gene: 170750620

Centisome position: 73.76

GC content: 72.82

Gene sequence:

>1056_bases
ATGTCTTCCGAAGAGAGAAACCGGGACCCGGACGCGGCACCGGCCGGGGGTGAGGCGCCGGGCGGCGAGGTCGCCTGCCT
GCGGTTCGAGCCGCCGGAGGATCGAGAGGCGCTCGGCCGGGCGTGGCAGGATCACCTCGCGCCGATCTTCGACGTGAGCT
TCCGCCCGGAGACCGACCTCACCGTCCCGATCGCGATGCGCAGCTACCACCTCGGCGACCTGCTGGTCGGCGACGTTGTG
GCGCCGGCCCACACCCTCGTGCGGACCCGGGAGATGATCGGCCAGCAGGGCCTCGACCACATCCTGCTGCAGTTCTACCG
GCGGGGGCAGAGCCGCGTGGAGACCGATCAGGGCACCGGGCCCGTGAACGAGGTGCAGTGCATCGTCTTCGACCTCGCCC
AGCCCGTGCGCATCGTGGCGGGCGCCGTCGACGCCACGAACGTCGTGATCCCCCGCGCCCTGCTGGAGAAGCAGGGCTGC
CACCCCGACGCCCTGCACGGCCGCTCCCTCGACCACGACGGCGACCCGTTCGGGCGGCTGGTCCACAACTTCGTCGCCAA
CGTGGTCGCCTGCGGCGACCTCCTCGACCGCCGCGAGGCCCTGGCGGCCTCGGCGGCGATCACCCAGCTCTGCGCCAGCT
GGCTGCGCGGGCAGGAGGAGGGGCGCCCCGCGCAGCACCAGGACGTCCGGATCCGGGTCCGCCGCCTGGTCGAGGCGGAG
CTCGGCAACCCGAAGCTGACGCCCGCCCTGATCGCGACGCGGCTCGGCCTGTCGCGCTCGACCCTGTACCGGCTGTTCGC
CCCCAACGGCATCGTGGCGTATATCCGCGACCGCCGCCTCATGGCGGCGATGCGGATGCTCGTGCGCGACGATGCCCCCA
AACCCCTGCGCGTCTCGCAGGTCGCCTTCGCGGTCGGCTTCTCGGACGAGCGGACCTTCCGGCGGGCGTTCAAGCGCCGG
TTCGGCTTCATCCCGAGCGACGCGTCCCAGCGCCTGGACACCGGCCCCGAACCCGCGCCCGGCGCCGTCCTGCGCAACTG
GATCGAGAGCCTCTGA

Upstream 100 bases:

>100_bases
GCTAACGTGCGGGATGACCGGACCGCGTTGCCACGCGTCAACTTGGGGCAGGCCCTCGTTCTTCATCGGTCGTGCTCACA
GCAGGTGTCAGGCTCTACGT

Downstream 100 bases:

>100_bases
CGTGCCGGGCCGGTCCGCCGGACGGCGGCGCGGCGGCGCGCCCGCTCGCGTCCTGTCCCTCTGTCTGTCCCTCTCCCTGT
GTTTCGCGGCCGCCGCGCCG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSSEERNRDPDAAPAGGEAPGGEVACLRFEPPEDREALGRAWQDHLAPIFDVSFRPETDLTVPIAMRSYHLGDLLVGDVV
APAHTLVRTREMIGQQGLDHILLQFYRRGQSRVETDQGTGPVNEVQCIVFDLAQPVRIVAGAVDATNVVIPRALLEKQGC
HPDALHGRSLDHDGDPFGRLVHNFVANVVACGDLLDRREALAASAAITQLCASWLRGQEEGRPAQHQDVRIRVRRLVEAE
LGNPKLTPALIATRLGLSRSTLYRLFAPNGIVAYIRDRRLMAAMRMLVRDDAPKPLRVSQVAFAVGFSDERTFRRAFKRR
FGFIPSDASQRLDTGPEPAPGAVLRNWIESL

Sequences:

>Translated_351_residues
MSSEERNRDPDAAPAGGEAPGGEVACLRFEPPEDREALGRAWQDHLAPIFDVSFRPETDLTVPIAMRSYHLGDLLVGDVV
APAHTLVRTREMIGQQGLDHILLQFYRRGQSRVETDQGTGPVNEVQCIVFDLAQPVRIVAGAVDATNVVIPRALLEKQGC
HPDALHGRSLDHDGDPFGRLVHNFVANVVACGDLLDRREALAASAAITQLCASWLRGQEEGRPAQHQDVRIRVRRLVEAE
LGNPKLTPALIATRLGLSRSTLYRLFAPNGIVAYIRDRRLMAAMRMLVRDDAPKPLRVSQVAFAVGFSDERTFRRAFKRR
FGFIPSDASQRLDTGPEPAPGAVLRNWIESL
>Mature_350_residues
SSEERNRDPDAAPAGGEAPGGEVACLRFEPPEDREALGRAWQDHLAPIFDVSFRPETDLTVPIAMRSYHLGDLLVGDVVA
PAHTLVRTREMIGQQGLDHILLQFYRRGQSRVETDQGTGPVNEVQCIVFDLAQPVRIVAGAVDATNVVIPRALLEKQGCH
PDALHGRSLDHDGDPFGRLVHNFVANVVACGDLLDRREALAASAAITQLCASWLRGQEEGRPAQHQDVRIRVRRLVEAEL
GNPKLTPALIATRLGLSRSTLYRLFAPNGIVAYIRDRRLMAAMRMLVRDDAPKPLRVSQVAFAVGFSDERTFRRAFKRRF
GFIPSDASQRLDTGPEPAPGAVLRNWIESL

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=265, Percent_Identity=26.0377358490566, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38750; Mature: 38618

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEERNRDPDAAPAGGEAPGGEVACLRFEPPEDREALGRAWQDHLAPIFDVSFRPETDL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCC
TVPIAMRSYHLGDLLVGDVVAPAHTLVRTREMIGQQGLDHILLQFYRRGQSRVETDQGTG
EEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCCCCC
PVNEVQCIVFDLAQPVRIVAGAVDATNVVIPRALLEKQGCHPDALHGRSLDHDGDPFGRL
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VHNFVANVVACGDLLDRREALAASAAITQLCASWLRGQEEGRPAQHQDVRIRVRRLVEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LGNPKLTPALIATRLGLSRSTLYRLFAPNGIVAYIRDRRLMAAMRMLVRDDAPKPLRVSQ
CCCCCCCHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHH
VAFAVGFSDERTFRRAFKRRFGFIPSDASQRLDTGPEPAPGAVLRNWIESL
HHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
SSEERNRDPDAAPAGGEAPGGEVACLRFEPPEDREALGRAWQDHLAPIFDVSFRPETDL
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCC
TVPIAMRSYHLGDLLVGDVVAPAHTLVRTREMIGQQGLDHILLQFYRRGQSRVETDQGTG
EEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCCCCC
PVNEVQCIVFDLAQPVRIVAGAVDATNVVIPRALLEKQGCHPDALHGRSLDHDGDPFGRL
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VHNFVANVVACGDLLDRREALAASAAITQLCASWLRGQEEGRPAQHQDVRIRVRRLVEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LGNPKLTPALIATRLGLSRSTLYRLFAPNGIVAYIRDRRLMAAMRMLVRDDAPKPLRVSQ
CCCCCCCHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHH
VAFAVGFSDERTFRRAFKRRFGFIPSDASQRLDTGPEPAPGAVLRNWIESL
HHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]