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The map label for this gene is glnH [H]

Identifier: 170750620

GI number: 170750620

Start: 4480727

End: 4481917

Strand: Reverse

Name: glnH [H]

Synonym: Mrad2831_4230

Alternate gene names: 170750620

Gene position: 4481917-4480727 (Counterclockwise)

Preceding gene: 170750621

Following gene: 170750613

Centisome position: 73.74

GC content: 76.41

Gene sequence:

>1191_bases
GTGCCGGGCCGGTCCGCCGGACGGCGGCGCGGCGGCGCGCCCGCTCGCGTCCTGTCCCTCTGTCTGTCCCTCTCCCTGTG
TTTCGCGGCCGCCGCGCCGCTCGCCGCGGCCCCCGTCCGGGCCGAGACCGCGGACGCGGCCCCCGCGCTCCGCACCGGCG
AGCCCGAGACGTGGCGGGTCGCGACGCATCCGGTGCCGCCCCTGGTCATGGACGAGGACGGCCGGCTGCGCGGGTTCAGC
ATCGATCTCTGGAACGCCGTCGCGCGGGAGCTCGGCGTCCGGACGGCCTATGTGCGCGTCGACGACCTGCCGGCGCTGTT
CGCGGCGGTCTCGGACGGGCGCGCGGACCTCGCCATCGCGGCGGTGTCGATCACCGCGGAGCGCGAGCGGCGGTTCGACT
TCTCGGTCACGATGCTGGAGACCGGCCTGCGCATCGCCGTCCGGGCGGAGCCGGACGCCACCGGCTCGGCCACCGCGCGG
GCCCTCCGGGCGCTCCTGAGCGACGCCGCCTTCCTGCAGGTCCTCCTGGGGCTCGCCGCCCTGATCCTGGCGGTGGCGGC
CCTGGTCTGGTGGCTCGAGCGGCGCCACCCCGGCGGCATGGCGGCGCGCTCGGGACCGGCGCGCGGCTTCGCCCACGTCG
TCTGGTGGGCCCTGAGCAGCCTCGCCGCGCAGGCGGAGGAGATGCCGCGCAGCCCCCTGGCGCGGGCCGTCACGGTCGTC
TGGCTGTTCACCTGCATCGCCCTGGTGGCGTGGTTCACCGCGGGCCTGACCAGCACGGCCACGGTGGAGCGCCTGCGCGG
CGCGGTCAACGGCCCGCAGGACCTGCCGGGCAAGCGGGTGGGCACGGTCGCCGACACCACCTCGGTCGCCTACCTGGCGG
ACCATTTCGCCACCCCGGTGAGCTTCGCGACGCTGGAGGCGGCCTGCGCGGCCCTGCAGGCCGGCACGGTCGCGGCGGTC
GTCTACGACGCCCCCGCGCTGGGCTACTACGCGACCCGGCCCGGCCACGAGGCCCTGCGCCTGGTCGGGGGCGCCTTCAA
CCGGCAATCCTACGGCATCCTGTTCCCGGCCAACGATCCCCGGCGCAAGCGCGTCAACCAGGCCCTTCTCGGCCTGCGGG
AGGACGGCCGCTACGACGAGATCTACGGCCGCTGGTTCGGCTCCGAGAGCGGCGAGTCCCAGGGCCGCTGA

Upstream 100 bases:

>100_bases
CGGTTCGGCTTCATCCCGAGCGACGCGTCCCAGCGCCTGGACACCGGCCCCGAACCCGCGCCCGGCGCCGTCCTGCGCAA
CTGGATCGAGAGCCTCTGAC

Downstream 100 bases:

>100_bases
GGCGCGCCGCGGTAGGCCTCGGCCGGGTGGCGGGCGGGCAGCCGGTCCCCCTGGCCGAACAGCTTCGCCCGCAGCGAGCC
CTCGGCGTAGGCGGTCTTGT

Product: extracellular solute-binding protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: GlnBP [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPGRSAGRRRGGAPARVLSLCLSLSLCFAAAAPLAAAPVRAETADAAPALRTGEPETWRVATHPVPPLVMDEDGRLRGFS
IDLWNAVARELGVRTAYVRVDDLPALFAAVSDGRADLAIAAVSITAERERRFDFSVTMLETGLRIAVRAEPDATGSATAR
ALRALLSDAAFLQVLLGLAALILAVAALVWWLERRHPGGMAARSGPARGFAHVVWWALSSLAAQAEEMPRSPLARAVTVV
WLFTCIALVAWFTAGLTSTATVERLRGAVNGPQDLPGKRVGTVADTTSVAYLADHFATPVSFATLEAACAALQAGTVAAV
VYDAPALGYYATRPGHEALRLVGGAFNRQSYGILFPANDPRRKRVNQALLGLREDGRYDEIYGRWFGSESGESQGR

Sequences:

>Translated_396_residues
MPGRSAGRRRGGAPARVLSLCLSLSLCFAAAAPLAAAPVRAETADAAPALRTGEPETWRVATHPVPPLVMDEDGRLRGFS
IDLWNAVARELGVRTAYVRVDDLPALFAAVSDGRADLAIAAVSITAERERRFDFSVTMLETGLRIAVRAEPDATGSATAR
ALRALLSDAAFLQVLLGLAALILAVAALVWWLERRHPGGMAARSGPARGFAHVVWWALSSLAAQAEEMPRSPLARAVTVV
WLFTCIALVAWFTAGLTSTATVERLRGAVNGPQDLPGKRVGTVADTTSVAYLADHFATPVSFATLEAACAALQAGTVAAV
VYDAPALGYYATRPGHEALRLVGGAFNRQSYGILFPANDPRRKRVNQALLGLREDGRYDEIYGRWFGSESGESQGR
>Mature_395_residues
PGRSAGRRRGGAPARVLSLCLSLSLCFAAAAPLAAAPVRAETADAAPALRTGEPETWRVATHPVPPLVMDEDGRLRGFSI
DLWNAVARELGVRTAYVRVDDLPALFAAVSDGRADLAIAAVSITAERERRFDFSVTMLETGLRIAVRAEPDATGSATARA
LRALLSDAAFLQVLLGLAALILAVAALVWWLERRHPGGMAARSGPARGFAHVVWWALSSLAAQAEEMPRSPLARAVTVVW
LFTCIALVAWFTAGLTSTATVERLRGAVNGPQDLPGKRVGTVADTTSVAYLADHFATPVSFATLEAACAALQAGTVAAVV
YDAPALGYYATRPGHEALRLVGGAFNRQSYGILFPANDPRRKRVNQALLGLREDGRYDEIYGRWFGSESGESQGR

Specific function: Involved in a glutamine-transport system glnHPQ [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Homo sapiens, GI28605145, Length=358, Percent_Identity=23.463687150838, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI55770854, Length=346, Percent_Identity=26.3005780346821, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4504117, Length=347, Percent_Identity=22.7665706051873, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI28416444, Length=347, Percent_Identity=22.7665706051873, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI197313638, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI197313636, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4504125, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI153946391, Length=364, Percent_Identity=24.4505494505494, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI167003331, Length=306, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI134304848, Length=395, Percent_Identity=23.5443037974684, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI74275354, Length=378, Percent_Identity=23.5449735449735, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI134304851, Length=378, Percent_Identity=23.5449735449735, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI55770852, Length=376, Percent_Identity=23.6702127659574, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI157384977, Length=369, Percent_Identity=23.3062330623306, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI62988346, Length=345, Percent_Identity=25.5072463768116, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787031, Length=142, Percent_Identity=34.5070422535211, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25147808, Length=301, Percent_Identity=26.9102990033223, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193208538, Length=348, Percent_Identity=23.5632183908046, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988861, Length=371, Percent_Identity=21.5633423180593, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648559, Length=363, Percent_Identity=23.9669421487603, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI116007354, Length=384, Percent_Identity=23.9583333333333, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI62484334, Length=367, Percent_Identity=23.1607629427793, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281359676, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI62473398, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI62473410, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281359678, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281359680, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI62473388, Length=343, Percent_Identity=24.7813411078717, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007112, Length=349, Percent_Identity=21.4899713467049, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007114, Length=349, Percent_Identity=21.4899713467049, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644257, Length=303, Percent_Identity=24.4224422442244, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 42083; Mature: 41952

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRSAGRRRGGAPARVLSLCLSLSLCFAAAAPLAAAPVRAETADAAPALRTGEPETWRV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEE
ATHPVPPLVMDEDGRLRGFSIDLWNAVARELGVRTAYVRVDDLPALFAAVSDGRADLAIA
ECCCCCCEEECCCCCEEEEEEHHHHHHHHHHCCEEEEEEECCHHHHHHHHCCCCCCEEEE
AVSITAERERRFDFSVTMLETGLRIAVRAEPDATGSATARALRALLSDAAFLQVLLGLAA
EEEEEHHHHHCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LILAVAALVWWLERRHPGGMAARSGPARGFAHVVWWALSSLAAQAEEMPRSPLARAVTVV
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WLFTCIALVAWFTAGLTSTATVERLRGAVNGPQDLPGKRVGTVADTTSVAYLADHFATPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
SFATLEAACAALQAGTVAAVVYDAPALGYYATRPGHEALRLVGGAFNRQSYGILFPANDP
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCH
RRKRVNQALLGLREDGRYDEIYGRWFGSESGESQGR
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PGRSAGRRRGGAPARVLSLCLSLSLCFAAAAPLAAAPVRAETADAAPALRTGEPETWRV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEE
ATHPVPPLVMDEDGRLRGFSIDLWNAVARELGVRTAYVRVDDLPALFAAVSDGRADLAIA
ECCCCCCEEECCCCCEEEEEEHHHHHHHHHHCCEEEEEEECCHHHHHHHHCCCCCCEEEE
AVSITAERERRFDFSVTMLETGLRIAVRAEPDATGSATARALRALLSDAAFLQVLLGLAA
EEEEEHHHHHCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LILAVAALVWWLERRHPGGMAARSGPARGFAHVVWWALSSLAAQAEEMPRSPLARAVTVV
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WLFTCIALVAWFTAGLTSTATVERLRGAVNGPQDLPGKRVGTVADTTSVAYLADHFATPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
SFATLEAACAALQAGTVAAVVYDAPALGYYATRPGHEALRLVGGAFNRQSYGILFPANDP
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCH
RRKRVNQALLGLREDGRYDEIYGRWFGSESGESQGR
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]