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The map label for this gene is ttuB [H]

Identifier: 170750530

GI number: 170750530

Start: 4393755

End: 4395074

Strand: Reverse

Name: ttuB [H]

Synonym: Mrad2831_4137

Alternate gene names: 170750530

Gene position: 4395074-4393755 (Counterclockwise)

Preceding gene: 170750531

Following gene: 170750529

Centisome position: 72.31

GC content: 69.39

Gene sequence:

>1320_bases
GTGAACGTCTCCGAACACGCCAAGCATCCGCTCGAGGCCGCGACCATGCGCCGGGTCATTCTCCGGCTCGTGCCGTTCCT
GATGCTCTGCTACTTCTTCGCGTTGCTGGATCGGGTGAACGTGGGCTTCGCCGCCCTGCAGATGAACAAGGATCTCGGGC
TCACCCCGGCCATGTTCGGCTTCGCGGCGAGCCTGTTCTTCGTGTCCTACTTCCTGGTCGAAGTCCCGAGCAACCTCGCC
CTGCAGAAGGTCGGGGCGCGGCGCTGGATCGCCCGGATCATGATCACCTGGGGCCTCGTCACCATCGGCATGGCCCTCGT
GACCGGGCCCCACTCCCTCTACGTGATGCGCTTCATCCTGGGCGCGGCGGAGGCCGGGTTCTTCCCGGGCGCGATCCTCT
ACCTGACCTACTGGCTGCCGAGCGCCTACCGGGCGCGGATCCTGGCGACCTTCACGGTCTCGATCCCGCTGGCGACCTTC
CTCGGCTCGCCCCTGTCGGTCACGCTCCTCGAACTCGACGGCCTGCTCGGCCTCAAGGGCTGGCAGTGGCTGTTCGTGCT
GGAGGGCCTGCCGACCGTGTGCCTCGGCATCGCCTGCCTGTTCGTCCTGACCGACCGCCCCCGCGACGCGCGCTGGCTGA
AGGACGACGAGCGCGCCTGGCTCGTCGGGCGCCTCGACGACGAGGCGGGCAAGCGCAAGCCCATCGGCCACATCTCCCTG
TGGCAGCTCGCCCGCAACAAGTACTTCCTGACGATGGCTCTGGTCTGCTCCGGCGCTTCAGCGACGGGGAGCGTGCTCTC
GGTCTGGCAGCCGCAGATGATCAAGTCCTTCGGCCTGACGAACCTCCAGACCGGCTTCGTCAACGCGATCCCCTACGGCA
TCGCCACGGTGCTGATGGTGCTCTGGGGCCGCCACTCCGACCGCCGGGGCGAGCGGCGCTGGCACACGGCGATCCCGCTG
CTGCTCGCGTCCTTCGGGCTCGCGTATCTGAACCTCACCGCGGGCATCGCGACGGCCGTCATGGCCGTGACCTTCGCCCT
CGTCGGCGCCTACTCCTTCAAGGGGCCGTTCTGGGCGCTCTCCGCCGGGTGGCTGTCCCCGGGGACGCTGGCGGCCGGGC
TCGCCGGCATCAACGCCATCGCCAATCTGATCGGCGGCGGCCTGATGGTGAACGTGGTCGGCCTCGTGAAGGACGCCACC
GGCAGCTTCGCCCTCGGGATGCTCCCCGTCGCCGCGCTGGATGCCGCCGCCGCGATCTGCGTGATCCTGATCAGCCGCGC
CCATGCCCGCGAGGCCCGGACGGCGGCGCTGCCAGCCTGA

Upstream 100 bases:

>100_bases
GCGAGGGGATCTGATCCCCTCCGGGCAGGACCGCACCACCGGGGCTCAAGGGCGCGGGACGTCACGCGAGCCGCATCTCG
ACAACAAGGGAGGTTGGGAC

Downstream 100 bases:

>100_bases
TCCACCGCTCCCGCACCCACACCGAGGCCACGCGATGTCGTTCTTCGCTCCCCCGCCGGCCGTGACGGCCGAGGTCTTCA
CGCGCCTGCCCGACCGCTTC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNVSEHAKHPLEAATMRRVILRLVPFLMLCYFFALLDRVNVGFAALQMNKDLGLTPAMFGFAASLFFVSYFLVEVPSNLA
LQKVGARRWIARIMITWGLVTIGMALVTGPHSLYVMRFILGAAEAGFFPGAILYLTYWLPSAYRARILATFTVSIPLATF
LGSPLSVTLLELDGLLGLKGWQWLFVLEGLPTVCLGIACLFVLTDRPRDARWLKDDERAWLVGRLDDEAGKRKPIGHISL
WQLARNKYFLTMALVCSGASATGSVLSVWQPQMIKSFGLTNLQTGFVNAIPYGIATVLMVLWGRHSDRRGERRWHTAIPL
LLASFGLAYLNLTAGIATAVMAVTFALVGAYSFKGPFWALSAGWLSPGTLAAGLAGINAIANLIGGGLMVNVVGLVKDAT
GSFALGMLPVAALDAAAAICVILISRAHAREARTAALPA

Sequences:

>Translated_439_residues
MNVSEHAKHPLEAATMRRVILRLVPFLMLCYFFALLDRVNVGFAALQMNKDLGLTPAMFGFAASLFFVSYFLVEVPSNLA
LQKVGARRWIARIMITWGLVTIGMALVTGPHSLYVMRFILGAAEAGFFPGAILYLTYWLPSAYRARILATFTVSIPLATF
LGSPLSVTLLELDGLLGLKGWQWLFVLEGLPTVCLGIACLFVLTDRPRDARWLKDDERAWLVGRLDDEAGKRKPIGHISL
WQLARNKYFLTMALVCSGASATGSVLSVWQPQMIKSFGLTNLQTGFVNAIPYGIATVLMVLWGRHSDRRGERRWHTAIPL
LLASFGLAYLNLTAGIATAVMAVTFALVGAYSFKGPFWALSAGWLSPGTLAAGLAGINAIANLIGGGLMVNVVGLVKDAT
GSFALGMLPVAALDAAAAICVILISRAHAREARTAALPA
>Mature_439_residues
MNVSEHAKHPLEAATMRRVILRLVPFLMLCYFFALLDRVNVGFAALQMNKDLGLTPAMFGFAASLFFVSYFLVEVPSNLA
LQKVGARRWIARIMITWGLVTIGMALVTGPHSLYVMRFILGAAEAGFFPGAILYLTYWLPSAYRARILATFTVSIPLATF
LGSPLSVTLLELDGLLGLKGWQWLFVLEGLPTVCLGIACLFVLTDRPRDARWLKDDERAWLVGRLDDEAGKRKPIGHISL
WQLARNKYFLTMALVCSGASATGSVLSVWQPQMIKSFGLTNLQTGFVNAIPYGIATVLMVLWGRHSDRRGERRWHTAIPL
LLASFGLAYLNLTAGIATAVMAVTFALVGAYSFKGPFWALSAGWLSPGTLAAGLAGINAIANLIGGGLMVNVVGLVKDAT
GSFALGMLPVAALDAAAAICVILISRAHAREARTAALPA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=434, Percent_Identity=34.5622119815668, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082320, Length=447, Percent_Identity=24.6085011185682, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367379, Length=429, Percent_Identity=23.3100233100233, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789152, Length=330, Percent_Identity=23.030303030303, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789515, Length=355, Percent_Identity=25.9154929577465, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=199, Percent_Identity=28.643216080402, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=324, Percent_Identity=23.1481481481481, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324410, Length=168, Percent_Identity=27.9761904761905, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=304, Percent_Identity=23.3552631578947, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=182, Percent_Identity=28.021978021978, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=238, Percent_Identity=24.3697478991597, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=317, Percent_Identity=23.6593059936909, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47429; Mature: 47429

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSEHAKHPLEAATMRRVILRLVPFLMLCYFFALLDRVNVGFAALQMNKDLGLTPAMFG
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
FAASLFFVSYFLVEVPSNLALQKVGARRWIARIMITWGLVTIGMALVTGPHSLYVMRFIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAAEAGFFPGAILYLTYWLPSAYRARILATFTVSIPLATFLGSPLSVTLLELDGLLGLKG
HHHHCCCCCHHHHHHHHHCCHHHHHHHHEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCC
WQWLFVLEGLPTVCLGIACLFVLTDRPRDARWLKDDERAWLVGRLDDEAGKRKPIGHISL
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHH
WQLARNKYFLTMALVCSGASATGSVLSVWQPQMIKSFGLTNLQTGFVNAIPYGIATVLMV
HHHHCCCHHEEHHHHHCCCCCCCCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LWGRHSDRRGERRWHTAIPLLLASFGLAYLNLTAGIATAVMAVTFALVGAYSFKGPFWAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
SAGWLSPGTLAAGLAGINAIANLIGGGLMVNVVGLVKDATGSFALGMLPVAALDAAAAIC
ECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VILISRAHAREARTAALPA
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNVSEHAKHPLEAATMRRVILRLVPFLMLCYFFALLDRVNVGFAALQMNKDLGLTPAMFG
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
FAASLFFVSYFLVEVPSNLALQKVGARRWIARIMITWGLVTIGMALVTGPHSLYVMRFIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAAEAGFFPGAILYLTYWLPSAYRARILATFTVSIPLATFLGSPLSVTLLELDGLLGLKG
HHHHCCCCCHHHHHHHHHCCHHHHHHHHEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCC
WQWLFVLEGLPTVCLGIACLFVLTDRPRDARWLKDDERAWLVGRLDDEAGKRKPIGHISL
CHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHH
WQLARNKYFLTMALVCSGASATGSVLSVWQPQMIKSFGLTNLQTGFVNAIPYGIATVLMV
HHHHCCCHHEEHHHHHCCCCCCCCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LWGRHSDRRGERRWHTAIPLLLASFGLAYLNLTAGIATAVMAVTFALVGAYSFKGPFWAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
SAGWLSPGTLAAGLAGINAIANLIGGGLMVNVVGLVKDATGSFALGMLPVAALDAAAAIC
ECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VILISRAHAREARTAALPA
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]