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The map label for this gene is cimH [H]

Identifier: 170750522

GI number: 170750522

Start: 4384798

End: 4386162

Strand: Direct

Name: cimH [H]

Synonym: Mrad2831_4129

Alternate gene names: 170750522

Gene position: 4384798-4386162 (Clockwise)

Preceding gene: 170750519

Following gene: 170750523

Centisome position: 72.14

GC content: 69.23

Gene sequence:

>1365_bases
ATGACTGCGCGTGCCGCTGCCGGGTCCACGGTCGCGACCTCGACCCGCTCGATATCGACGCCGAAACCCTTCTGGACTCA
GGCCATGGAGACGCGGGTCGGCATCGTCCCGCTGCCCGTCTATGTGCTGCTGCTGGCCCTCATCGCGGCCTTCGCCGTCA
GGGGTAAGATCTCGGGCGAAGTGACGGTGATGATCGCCGTACTGGTCGCGGGGGGCTTCACCTGCGCCGAGATCGGCCGG
CGGATCCCGCTGCTGCGGGCGGTCGGCGGATCGTCCCTGGTGACGATCTTCCTGCCCTCGTTCCTCGTCGCCCACCAGCT
CCTGCCGGCGCCGCTGGTGCAGTCGGTGACGACCTTCACCAAGTCGACGAACTTCATCTACCTGTTCATCACTGCCGTGG
TGGTCGGCTCGATCCTGAGCATGGACCGTCGGGTGCTGATCCAGGGCTTCGCCAAGATCTTCGTGCCCCTGGCGCTGGGG
TCGCTCGCCGGCCTCCTCGTGGGCGGAAGTGTCGGCTGGCTCGTCGGCATCGGCTTCTGGCGGTCGATCCTCTACGTCGT
GGTGCCCGTGATGGCCGGGGGCGTCGGCGAGGGCGCGATCCCGCTCTCGGTCGGCTACGCGGAGGCGCTGGGCGTCGACC
ACGGCGGGATGCTGGGGCAGATCCTGCCGCTGGTGTTCTTCGGGAACCTCGTCGCCATCGTCATCTGCGGCGCCCTGAAC
ACGCTGGGCAAGCGCCGCCCCGACCTCACCGGCAACGGCCGGCTCCAGCCCGCCGCTGACGGAGACACGGATGCCGACCA
CGGTGCGGCTCACCGCAACACCTCCGGGATCGACGTCGCCACCGTCGCGGCCGGCGGCATCACCGGCATCGCCGTCTACG
TCTTCGGCACGCTGATCCACGCGCTGATCGGATTACCCGCGCCGGTGGCGATGCTGTTCCTCGTCGTCCTCGCGAAGCTG
CTGCGGGCGGTTCCGGCCTCGCTGGAGGAAGGCGCCCGCGTGGTGTTCCGCTTCTTCGTGGTGGCGGTGACCTATCCGCT
GCTGTTCAGCACGGCGGTGGCGCTGACTCCCTGGCACGAGCTGGTCGAGGCGTTCCACCCGGCCAACCTCGTCACCATCG
TGGCGACCGTGCTCGCGCTGACCGGCACCGGCTACGTCGTCGGGCGCTGGCTCGCCATGTACCCGATCGAGACCGCGATC
GTGAACGCCTGCCACAGCGGCCTCGGCGGCACGGGCGACGTGATGATCCTGACCGCCGCCGAGCGGATGGAACTGATGCC
CTTCGCCCAGGTCGCGACGCGGATCGGCGGGGCCCTCACCGTCACCGTGGCCATCGTCGCGATGGCGCATTTCAAGATCG
CCTGA

Upstream 100 bases:

>100_bases
TTCATTTTACTCGACCATGCCGCTGCGGGACAAGGCGCGGGGCGACGCCTGCCCGACACGATGCGACTCCGGCTGAACAC
GGGGCGATGCGGAGGAAACG

Downstream 100 bases:

>100_bases
CGGAGGCGCGCCGTGCTGATGCGCTCCAAGCTGTTCGTCCCGGCCTCCCGGCCCGAATTGTTCGCGAAGGCCGCCACCGG
CCCCGCCGACGCCCTCTCCT

Product: citrate carrier protein

Products: NA

Alternate protein names: Citrate/malate-proton symporter [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTARAAAGSTVATSTRSISTPKPFWTQAMETRVGIVPLPVYVLLLALIAAFAVRGKISGEVTVMIAVLVAGGFTCAEIGR
RIPLLRAVGGSSLVTIFLPSFLVAHQLLPAPLVQSVTTFTKSTNFIYLFITAVVVGSILSMDRRVLIQGFAKIFVPLALG
SLAGLLVGGSVGWLVGIGFWRSILYVVVPVMAGGVGEGAIPLSVGYAEALGVDHGGMLGQILPLVFFGNLVAIVICGALN
TLGKRRPDLTGNGRLQPAADGDTDADHGAAHRNTSGIDVATVAAGGITGIAVYVFGTLIHALIGLPAPVAMLFLVVLAKL
LRAVPASLEEGARVVFRFFVVAVTYPLLFSTAVALTPWHELVEAFHPANLVTIVATVLALTGTGYVVGRWLAMYPIETAI
VNACHSGLGGTGDVMILTAAERMELMPFAQVATRIGGALTVTVAIVAMAHFKIA

Sequences:

>Translated_454_residues
MTARAAAGSTVATSTRSISTPKPFWTQAMETRVGIVPLPVYVLLLALIAAFAVRGKISGEVTVMIAVLVAGGFTCAEIGR
RIPLLRAVGGSSLVTIFLPSFLVAHQLLPAPLVQSVTTFTKSTNFIYLFITAVVVGSILSMDRRVLIQGFAKIFVPLALG
SLAGLLVGGSVGWLVGIGFWRSILYVVVPVMAGGVGEGAIPLSVGYAEALGVDHGGMLGQILPLVFFGNLVAIVICGALN
TLGKRRPDLTGNGRLQPAADGDTDADHGAAHRNTSGIDVATVAAGGITGIAVYVFGTLIHALIGLPAPVAMLFLVVLAKL
LRAVPASLEEGARVVFRFFVVAVTYPLLFSTAVALTPWHELVEAFHPANLVTIVATVLALTGTGYVVGRWLAMYPIETAI
VNACHSGLGGTGDVMILTAAERMELMPFAQVATRIGGALTVTVAIVAMAHFKIA
>Mature_453_residues
TARAAAGSTVATSTRSISTPKPFWTQAMETRVGIVPLPVYVLLLALIAAFAVRGKISGEVTVMIAVLVAGGFTCAEIGRR
IPLLRAVGGSSLVTIFLPSFLVAHQLLPAPLVQSVTTFTKSTNFIYLFITAVVVGSILSMDRRVLIQGFAKIFVPLALGS
LAGLLVGGSVGWLVGIGFWRSILYVVVPVMAGGVGEGAIPLSVGYAEALGVDHGGMLGQILPLVFFGNLVAIVICGALNT
LGKRRPDLTGNGRLQPAADGDTDADHGAAHRNTSGIDVATVAAGGITGIAVYVFGTLIHALIGLPAPVAMLFLVVLAKLL
RAVPASLEEGARVVFRFFVVAVTYPLLFSTAVALTPWHELVEAFHPANLVTIVATVLALTGTGYVVGRWLAMYPIETAIV
NACHSGLGGTGDVMILTAAERMELMPFAQVATRIGGALTVTVAIVAMAHFKIA

Specific function: Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions. Is strictl

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 47099; Mature: 46967

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARAAAGSTVATSTRSISTPKPFWTQAMETRVGIVPLPVYVLLLALIAAFAVRGKISGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
VTVMIAVLVAGGFTCAEIGRRIPLLRAVGGSSLVTIFLPSFLVAHQLLPAPLVQSVTTFT
HHHHHHHHHHCCCHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
KSTNFIYLFITAVVVGSILSMDRRVLIQGFAKIFVPLALGSLAGLLVGGSVGWLVGIGFW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RSILYVVVPVMAGGVGEGAIPLSVGYAEALGVDHGGMLGQILPLVFFGNLVAIVICGALN
HHHHHHHHHHHHCCCCCCCCEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLGKRRPDLTGNGRLQPAADGDTDADHGAAHRNTSGIDVATVAAGGITGIAVYVFGTLIH
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHH
ALIGLPAPVAMLFLVVLAKLLRAVPASLEEGARVVFRFFVVAVTYPLLFSTAVALTPWHE
HHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LVEAFHPANLVTIVATVLALTGTGYVVGRWLAMYPIETAIVNACHSGLGGTGDVMILTAA
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEH
ERMELMPFAQVATRIGGALTVTVAIVAMAHFKIA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARAAAGSTVATSTRSISTPKPFWTQAMETRVGIVPLPVYVLLLALIAAFAVRGKISGE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 11566984 [H]