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The map label for this gene is bmrU [H]

Identifier: 170750504

GI number: 170750504

Start: 4364764

End: 4365717

Strand: Reverse

Name: bmrU [H]

Synonym: Mrad2831_4111

Alternate gene names: 170750504

Gene position: 4365717-4364764 (Counterclockwise)

Preceding gene: 170750508

Following gene: 170750503

Centisome position: 71.83

GC content: 71.7

Gene sequence:

>954_bases
ATGAGCACGCAAAGGCGTCGGGCCCTGCTGCTCTGCAACGCCAAGGCGCGCAACGGCGCCCTGGATCTGGACGAGGTGCG
GGGAATCCTGCGGGCGGGCGGCATCGAGCCGGAGGAGCCGCCGCCGGAGGCCGATTGCCGCGACGTGATCCGTGACCGGG
CCGGCGCGGTCGACCTCGTGATCCTCGGCGGCGGCGACGGCACCATGAACTACGCCGCGCCCGCCCTGGTGGAGAGCGGT
CTGCCCTTCGCGATCCTGCCGCTCGGCACGGCCAACGACCTCGCCCGCTCCCTCAACCTGCCGCTCGACCCCCTGGCGGC
GGCCCGCTTCATCCCGACCGCGCAGGCGCGGCCGGTGGATCTCGGCTGGGTCAACGGCCACTACTACTTCAACGTGGCGA
GCATCGGCTTCTCGGCGGAGCTCGCCGGCGAGCTGACCGCCGAATCCAAGAAGACCTGGGGCGTGCTCGGCTACGCGGTG
GCGGCGGTGCGGGTGCTGCGCCGGGTCCGGCCCTTCACGGTGACGATCGAGCACGACGGGGTGGTCGAGAAGGTCACCAC
CATCCAGGTCTCGGTGGGCAACGGCCGCCACTACGGCGGTGGCATGACCGTGGAGGAGAGTGCCGCGGTCGACGACGGCA
AGCTCGATTTCTACAGCCTGGAGATCAATCACTGGTGGCGTCTCCTCGCGCTGCTGCCCGCCCTGCGGCGGGGAACGCAG
GGGCGGGCGGGCGACGTGCGGGCGTTCCACACGCGGGAGATCCGGCTCTCGACCCGCAAGCCGCGGCCGGTGAACACCGA
CGGCGAGCTGACCACGCACACGCCCGCCCACTTCAAGGTCTTCCCGAAGATCCTGCAGGTCCTGGCCCCCGAACCGGTGC
GCGGTCCCACCCCCTTCGACCTCACCGCCCTGGGCAACCGCCTGTTCCCGACCAGCGAGGCGCCCCGCCTGTGA

Upstream 100 bases:

>100_bases
ATACCGCGTTCCAGACCGCCCGCTCCCTGCCGTGCCCCGAGGATCCCTTGTCCCGACCTGAGACCGAGTCGCCCCCCGGC
CCGCTTCCCGGGGGCACGCG

Downstream 100 bases:

>100_bases
CCGACCTGATCGAGCTCGCCAGCCAGCCCGCCGTCTGGGCCGCGCTCGCCACCCTGGTGGTGATGGAGGTGGTGCTCGGT
GTCGACAACCTGATCTTCAT

Product: putative lipid kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSTQRRRALLLCNAKARNGALDLDEVRGILRAGGIEPEEPPPEADCRDVIRDRAGAVDLVILGGGDGTMNYAAPALVESG
LPFAILPLGTANDLARSLNLPLDPLAAARFIPTAQARPVDLGWVNGHYYFNVASIGFSAELAGELTAESKKTWGVLGYAV
AAVRVLRRVRPFTVTIEHDGVVEKVTTIQVSVGNGRHYGGGMTVEESAAVDDGKLDFYSLEINHWWRLLALLPALRRGTQ
GRAGDVRAFHTREIRLSTRKPRPVNTDGELTTHTPAHFKVFPKILQVLAPEPVRGPTPFDLTALGNRLFPTSEAPRL

Sequences:

>Translated_317_residues
MSTQRRRALLLCNAKARNGALDLDEVRGILRAGGIEPEEPPPEADCRDVIRDRAGAVDLVILGGGDGTMNYAAPALVESG
LPFAILPLGTANDLARSLNLPLDPLAAARFIPTAQARPVDLGWVNGHYYFNVASIGFSAELAGELTAESKKTWGVLGYAV
AAVRVLRRVRPFTVTIEHDGVVEKVTTIQVSVGNGRHYGGGMTVEESAAVDDGKLDFYSLEINHWWRLLALLPALRRGTQ
GRAGDVRAFHTREIRLSTRKPRPVNTDGELTTHTPAHFKVFPKILQVLAPEPVRGPTPFDLTALGNRLFPTSEAPRL
>Mature_316_residues
STQRRRALLLCNAKARNGALDLDEVRGILRAGGIEPEEPPPEADCRDVIRDRAGAVDLVILGGGDGTMNYAAPALVESGL
PFAILPLGTANDLARSLNLPLDPLAAARFIPTAQARPVDLGWVNGHYYFNVASIGFSAELAGELTAESKKTWGVLGYAVA
AVRVLRRVRPFTVTIEHDGVVEKVTTIQVSVGNGRHYGGGMTVEESAAVDDGKLDFYSLEINHWWRLLALLPALRRGTQG
RAGDVRAFHTREIRLSTRKPRPVNTDGELTTHTPAHFKVFPKILQVLAPEPVRGPTPFDLTALGNRLFPTSEAPRL

Specific function: May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=251, Percent_Identity=27.0916334661355, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 34360; Mature: 34229

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQRRRALLLCNAKARNGALDLDEVRGILRAGGIEPEEPPPEADCRDVIRDRAGAVDLV
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEE
ILGGGDGTMNYAAPALVESGLPFAILPLGTANDLARSLNLPLDPLAAARFIPTAQARPVD
EEECCCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHCCCCCCCCCEE
LGWVNGHYYFNVASIGFSAELAGELTAESKKTWGVLGYAVAAVRVLRRVRPFTVTIEHDG
EEEECCEEEEEEEECCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
VVEKVTTIQVSVGNGRHYGGGMTVEESAAVDDGKLDFYSLEINHWWRLLALLPALRRGTQ
CEEEEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCC
GRAGDVRAFHTREIRLSTRKPRPVNTDGELTTHTPAHFKVFPKILQVLAPEPVRGPTPFD
CCCCCEEEEEEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEE
LTALGNRLFPTSEAPRL
HHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STQRRRALLLCNAKARNGALDLDEVRGILRAGGIEPEEPPPEADCRDVIRDRAGAVDLV
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEE
ILGGGDGTMNYAAPALVESGLPFAILPLGTANDLARSLNLPLDPLAAARFIPTAQARPVD
EEECCCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHCCCCCCCCCEE
LGWVNGHYYFNVASIGFSAELAGELTAESKKTWGVLGYAVAAVRVLRRVRPFTVTIEHDG
EEEECCEEEEEEEECCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
VVEKVTTIQVSVGNGRHYGGGMTVEESAAVDDGKLDFYSLEINHWWRLLALLPALRRGTQ
CEEEEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCC
GRAGDVRAFHTREIRLSTRKPRPVNTDGELTTHTPAHFKVFPKILQVLAPEPVRGPTPFD
CCCCCEEEEEEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEE
LTALGNRLFPTSEAPRL
HHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377 [H]