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The map label for this gene is blaA [H]

Identifier: 170750475

GI number: 170750475

Start: 4335081

End: 4335959

Strand: Direct

Name: blaA [H]

Synonym: Mrad2831_4082

Alternate gene names: 170750475

Gene position: 4335081-4335959 (Clockwise)

Preceding gene: 170750473

Following gene: 170750476

Centisome position: 71.33

GC content: 76.34

Gene sequence:

>879_bases
ATGATCGTCTGGACCCGCCGCGCCGTCGGCCTCGGCCTGCTCGCCGCGCCCTTCGCCCTCCCCGCGCGCGCCGTCGAGGC
GGAGCCGGACTGGACCGCGATCGAGCGCCGACTCGGTGGCCGCCTCGGGATCGCGGCCGCCTCGGCGGACCGCGTCCTCG
CCGCCTACCGCGCCGACGCGCGCTTCCCGATGTGCAGCACCTTCAAGGTCCTGGCGGCCGCGGCGGTGCTGGCGCGGGTC
GATGCCGGCCGCGAGACCCTCGGCCGGATCGTCACCTACGGTCCCGGCGATCTCCTGAGCTACGCCCCGGTCACCCGGAA
GGCGCTGGAGGCCGGCGGCGGGACCGGGCGGATGAGCGTCGCCGACCTGTGCGCGGCGACGCTGGTCTGGAGCGACAACG
CGGCCGCCAACCTGCTCCTGGCGGATCTCGGCGGCCCCGCAGCGCTGACCGCGTGGCTGCGGACGACCGGCGATCCCGTC
ACCCGCCTCGACCGGACCGAGCCGACCCTCAACACCGCCCTGCCCGGCGACCCGCGCGACACGACCACGCCGGACGCCAT
GCGGGCGACCCTGGGTCGGATCCTCCTCGGGACGACCCTGTCGCCGGCCTCGCGCGACCGGCTGGAGGCCTGGATGGTCG
CCTGCGAGACCGGCCGGAAACGCCTGCGGGCCGGCCTGCCGCCGGATTGGAGCGCGGGCGACAAGACCGGGAGCGGCGAC
AACGGCACCGTCAACGACGTGGCGATCCTGCGGCCGCCGGGGCGTGCGCCGATCCTCGTGGCGGTCTACGTCACGGGATC
GACGGCCTCCCCCGACACCTGCGCGGCGGCCTACGCGGAGATCGCCCGCCTCATCGCCGCGCGCGCCCAGTCCACCTGA

Upstream 100 bases:

>100_bases
GGGGCGGAGTTTCACGTGAAACACGCGCGGCCGCCCTATACCATCCCGGCGTCGCGGTGACGCGCCCGGGCGCGCGGCCG
CGATCTCGAACGGGGATGCC

Downstream 100 bases:

>100_bases
CCGAACGAGCCATGAAGACGCCCGCCAGGACATCTGCCAAGACGACCCGCGCCACGCTCGCCCTCGACAAGGCCGGCATC
CGCCACGGCCTCCACGTCTA

Product: beta-lactamase

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIVWTRRAVGLGLLAAPFALPARAVEAEPDWTAIERRLGGRLGIAAASADRVLAAYRADARFPMCSTFKVLAAAAVLARV
DAGRETLGRIVTYGPGDLLSYAPVTRKALEAGGGTGRMSVADLCAATLVWSDNAAANLLLADLGGPAALTAWLRTTGDPV
TRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRDRLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGD
NGTVNDVAILRPPGRAPILVAVYVTGSTASPDTCAAAYAEIARLIAARAQST

Sequences:

>Translated_292_residues
MIVWTRRAVGLGLLAAPFALPARAVEAEPDWTAIERRLGGRLGIAAASADRVLAAYRADARFPMCSTFKVLAAAAVLARV
DAGRETLGRIVTYGPGDLLSYAPVTRKALEAGGGTGRMSVADLCAATLVWSDNAAANLLLADLGGPAALTAWLRTTGDPV
TRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRDRLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGD
NGTVNDVAILRPPGRAPILVAVYVTGSTASPDTCAAAYAEIARLIAARAQST
>Mature_292_residues
MIVWTRRAVGLGLLAAPFALPARAVEAEPDWTAIERRLGGRLGIAAASADRVLAAYRADARFPMCSTFKVLAAAAVLARV
DAGRETLGRIVTYGPGDLLSYAPVTRKALEAGGGTGRMSVADLCAATLVWSDNAAANLLLADLGGPAALTAWLRTTGDPV
TRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRDRLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGD
NGTVNDVAILRPPGRAPILVAVYVTGSTASPDTCAAAYAEIARLIAARAQST

Specific function: Unknown

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30372; Mature: 30372

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVWTRRAVGLGLLAAPFALPARAVEAEPDWTAIERRLGGRLGIAAASADRVLAAYRADA
CEEECCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHCCC
RFPMCSTFKVLAAAAVLARVDAGRETLGRIVTYGPGDLLSYAPVTRKALEAGGGTGRMSV
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCHHHHCCHHHHHHHHCCCCCCCHHH
ADLCAATLVWSDNAAANLLLADLGGPAALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRD
HHHHHHHHEECCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCC
TTTPDAMRATLGRILLGTTLSPASRDRLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGD
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NGTVNDVAILRPPGRAPILVAVYVTGSTASPDTCAAAYAEIARLIAARAQST
CCCCCCEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVWTRRAVGLGLLAAPFALPARAVEAEPDWTAIERRLGGRLGIAAASADRVLAAYRADA
CEEECCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHCCC
RFPMCSTFKVLAAAAVLARVDAGRETLGRIVTYGPGDLLSYAPVTRKALEAGGGTGRMSV
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCHHHHCCHHHHHHHHCCCCCCCHHH
ADLCAATLVWSDNAAANLLLADLGGPAALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRD
HHHHHHHHEECCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCC
TTTPDAMRATLGRILLGTTLSPASRDRLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGD
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NGTVNDVAILRPPGRAPILVAVYVTGSTASPDTCAAAYAEIARLIAARAQST
CCCCCCEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1886608 [H]