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The map label for this gene is tag [H]

Identifier: 170750385

GI number: 170750385

Start: 4239160

End: 4239825

Strand: Direct

Name: tag [H]

Synonym: Mrad2831_3988

Alternate gene names: 170750385

Gene position: 4239160-4239825 (Clockwise)

Preceding gene: 170750384

Following gene: 170750386

Centisome position: 69.75

GC content: 72.22

Gene sequence:

>666_bases
GTGCTCGCCCCGGCGGTGGCGTTCCGCTCCTGTTCTCGTTACCATCGCCGCATGTCCGAGACCGGCCTCATCGATCATCC
CGACGGCTGCCCGCGCTGCTGGTGGGCCGGCCTCGACCCGCTCTACGTCGCCTATCACGACACCGAGTGGGGCGTGCCCG
AGCATGACGGCCGCGCCCTCTACGAGAAGCTGATCCTCGACGGCTTCCAGGCCGGCCTGTCGTGGATCACCATCCTGCGC
CGCCGGGACGGGTTCCGCGACGCCTTCGCCGGGTTCGATCCGGAGCGGATCGCCCGCTTCACCGAGGCGGACGTCGCGCG
GCTGATGGCCGACACCCGCATCATCCGCAACCGCGCCAAGATCCAGGGCACCGTCGCGGGCGCCCGGGCCTGGCTGCGGA
TCGAGGAGCGCGGCCCCGGCTTCGCGCGCTTCCTGTGGGACTTCGTCGACGGCCGGCCGGTCCAGGGCACCGCCCGGACC
CGCGCGGAGATCGCCACCGAGACGCCGGTCTCCCGGGCGATCGGGAAGGCCCTGAAGGCGGAGGGCTTCTCCTTCTGCGG
GCCGACGATCGTGCACGCCTTCATGCAGGCGGTGGGCATGGTCAACGACCACCTCGTCGGCTGCCACCGGCACGGGCCCT
GCGCCGAACTGGGCCGGATCCGGTGA

Upstream 100 bases:

>100_bases
CGCGGCGACGAGCGCGGCCGAGTAGGACCGCGAGGCGGCGGACGGGCTCGGCGCGGGGGCAGCGGCTCGTCCCGGCGCGC
CGAAGCGGCCGCGGAAGCCG

Downstream 100 bases:

>100_bases
GCGCGCCGCCGCGCGCGTGGCAGCGCATGCTCTCCGGCCGGCGCCTAGACCTCCTCGACCCGGCGCCCGGGGACATCGAG
ATCGCCGACATCGCCCACGG

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MLAPAVAFRSCSRYHRRMSETGLIDHPDGCPRCWWAGLDPLYVAYHDTEWGVPEHDGRALYEKLILDGFQAGLSWITILR
RRDGFRDAFAGFDPERIARFTEADVARLMADTRIIRNRAKIQGTVAGARAWLRIEERGPGFARFLWDFVDGRPVQGTART
RAEIATETPVSRAIGKALKAEGFSFCGPTIVHAFMQAVGMVNDHLVGCHRHGPCAELGRIR

Sequences:

>Translated_221_residues
MLAPAVAFRSCSRYHRRMSETGLIDHPDGCPRCWWAGLDPLYVAYHDTEWGVPEHDGRALYEKLILDGFQAGLSWITILR
RRDGFRDAFAGFDPERIARFTEADVARLMADTRIIRNRAKIQGTVAGARAWLRIEERGPGFARFLWDFVDGRPVQGTART
RAEIATETPVSRAIGKALKAEGFSFCGPTIVHAFMQAVGMVNDHLVGCHRHGPCAELGRIR
>Mature_221_residues
MLAPAVAFRSCSRYHRRMSETGLIDHPDGCPRCWWAGLDPLYVAYHDTEWGVPEHDGRALYEKLILDGFQAGLSWITILR
RRDGFRDAFAGFDPERIARFTEADVARLMADTRIIRNRAKIQGTVAGARAWLRIEERGPGFARFLWDFVDGRPVQGTART
RAEIATETPVSRAIGKALKAEGFSFCGPTIVHAFMQAVGMVNDHLVGCHRHGPCAELGRIR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=177, Percent_Identity=52.5423728813559, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 24793; Mature: 24793

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPAVAFRSCSRYHRRMSETGLIDHPDGCPRCWWAGLDPLYVAYHDTEWGVPEHDGRAL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHH
YEKLILDGFQAGLSWITILRRRDGFRDAFAGFDPERIARFTEADVARLMADTRIIRNRAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGTVAGARAWLRIEERGPGFARFLWDFVDGRPVQGTARTRAEIATETPVSRAIGKALKA
HHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
EGFSFCGPTIVHAFMQAVGMVNDHLVGCHRHGPCAELGRIR
CCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCC
>Mature Secondary Structure
MLAPAVAFRSCSRYHRRMSETGLIDHPDGCPRCWWAGLDPLYVAYHDTEWGVPEHDGRAL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHH
YEKLILDGFQAGLSWITILRRRDGFRDAFAGFDPERIARFTEADVARLMADTRIIRNRAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGTVAGARAWLRIEERGPGFARFLWDFVDGRPVQGTARTRAEIATETPVSRAIGKALKA
HHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
EGFSFCGPTIVHAFMQAVGMVNDHLVGCHRHGPCAELGRIR
CCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]