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The map label for this gene is ygfZ [C]

Identifier: 170750384

GI number: 170750384

Start: 4238233

End: 4239084

Strand: Direct

Name: ygfZ [C]

Synonym: Mrad2831_3987

Alternate gene names: 170750384

Gene position: 4238233-4239084 (Clockwise)

Preceding gene: 170750383

Following gene: 170750385

Centisome position: 69.73

GC content: 76.88

Gene sequence:

>852_bases
ATGCCCGTCGCCCTGCTGCCGGATCGCGCCCTGGTCACCGTCACCGGGCCGGACGCCACGACGCTGCTCCAGGGCGTCCT
GACCTGCAACGTCGAGACGCTCCGGCCCGGTGAGGCGCGCCTCGGCGCCCTGCTGACGCCGCAGGGCAAGATCCTGTTCG
ATTTCCTGATCTCGCGGATCCCGGACGGCTTCCGGTTCGACGTGCTGGCCGACAGGGCCGCGGACCTCGCCAAGCGCCTG
ACGCTCTACCGCCTGCGCGCGCAGGCGACCATCGCGGCCGACCCGACCGTCGCGGTCGCGGCGGCCTGGGCCGGCGCCAC
CCCGCCCGCCGCGGAGGCCGTGGCCGATACCCGCGCCGTCGATCTCGGTGCCCGCCTCTACGCCGCCGCGGGCGCCTTCT
CGGCGGACGCCGCCGAGGCCGACTACCACGCGCACCGGATCGCCCTCGGCGTGCCCGAGGGCGGGCGCGACTTCGCCTTC
GGCGACGCCTTCCCGCACGAGGCGCTGATGGATCAGCTCGGCGGCGTCGACTTCCGCAAGGGCTGCTATGTCGGCCAGGA
GGTGGTCTCGCGGATGCAGCACCGGGGCACGGCCCGGACCCGCATCCTGGCCGCAGCCTACCCGGACGCGGCGCCCGCGC
CCGGCACCGAGATCACGGCGGGCGGCAAGGTCCTCGGCACCGCGGGCAGCGCGGCCGGGAACCGCGGCCTCGCCACGATC
CGCCTCGACCGCCTGGGCGACGCGCTGGCCGCCGGCGAGACCCCGCGCGCGGGCGACCGCCCCGTGACGCTGGAGCGCCC
GGCCTGCGCGACCTTCGCCATGCCGGACGCGGCGACGAGCGCGGCCGAGTAG

Upstream 100 bases:

>100_bases
CGCGTGAGCGCGGACGGTTGAGGCGCGGGCGGTCAGCGACTACGTCCCGGATCCGCGGTCCGGCCCGCCGGACCGCCCGC
TCCCCGAGGAATCGCCGCCC

Downstream 100 bases:

>100_bases
GACCGCGAGGCGGCGGACGGGCTCGGCGCGGGGGCAGCGGCTCGTCCCGGCGCGCCGAAGCGGCCGCGGAAGCCGGTGCT
CGCCCCGGCGGTGGCGTTCC

Product: folate-binding protein YgfZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MPVALLPDRALVTVTGPDATTLLQGVLTCNVETLRPGEARLGALLTPQGKILFDFLISRIPDGFRFDVLADRAADLAKRL
TLYRLRAQATIAADPTVAVAAAWAGATPPAAEAVADTRAVDLGARLYAAAGAFSADAAEADYHAHRIALGVPEGGRDFAF
GDAFPHEALMDQLGGVDFRKGCYVGQEVVSRMQHRGTARTRILAAAYPDAAPAPGTEITAGGKVLGTAGSAAGNRGLATI
RLDRLGDALAAGETPRAGDRPVTLERPACATFAMPDAATSAAE

Sequences:

>Translated_283_residues
MPVALLPDRALVTVTGPDATTLLQGVLTCNVETLRPGEARLGALLTPQGKILFDFLISRIPDGFRFDVLADRAADLAKRL
TLYRLRAQATIAADPTVAVAAAWAGATPPAAEAVADTRAVDLGARLYAAAGAFSADAAEADYHAHRIALGVPEGGRDFAF
GDAFPHEALMDQLGGVDFRKGCYVGQEVVSRMQHRGTARTRILAAAYPDAAPAPGTEITAGGKVLGTAGSAAGNRGLATI
RLDRLGDALAAGETPRAGDRPVTLERPACATFAMPDAATSAAE
>Mature_282_residues
PVALLPDRALVTVTGPDATTLLQGVLTCNVETLRPGEARLGALLTPQGKILFDFLISRIPDGFRFDVLADRAADLAKRLT
LYRLRAQATIAADPTVAVAAAWAGATPPAAEAVADTRAVDLGARLYAAAGAFSADAAEADYHAHRIALGVPEGGRDFAFG
DAFPHEALMDQLGGVDFRKGCYVGQEVVSRMQHRGTARTRILAAAYPDAAPAPGTEITAGGKVLGTAGSAAGNRGLATIR
LDRLGDALAAGETPRAGDRPVTLERPACATFAMPDAATSAAE

Specific function: Folate-binding protein involved in regulating the level of ATP-dnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA-modifying ygfZ family [H]

Homologues:

Organism=Homo sapiens, GI58197556, Length=282, Percent_Identity=30.8510638297872, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71985951, Length=199, Percent_Identity=30.6532663316583, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24645123, Length=273, Percent_Identity=30.03663003663, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017703
- InterPro:   IPR006222 [H]

Pfam domain/function: PF01571 GCV_T [H]

EC number: NA

Molecular weight: Translated: 29183; Mature: 29052

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVALLPDRALVTVTGPDATTLLQGVLTCNVETLRPGEARLGALLTPQGKILFDFLISRI
CCEEECCCCEEEEEECCCHHHHHHHHHHCCCEECCCCCHHHCEEECCCCHHHHHHHHHHC
PDGFRFDVLADRAADLAKRLTLYRLRAQATIAADPTVAVAAAWAGATPPAAEAVADTRAV
CCCCEEHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEHHCCCCCCHHHHHHHHHHH
DLGARLYAAAGAFSADAAEADYHAHRIALGVPEGGRDFAFGDAFPHEALMDQLGGVDFRK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHH
GCYVGQEVVSRMQHRGTARTRILAAAYPDAAPAPGTEITAGGKVLGTAGSAAGNRGLATI
CCHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCEEECCCEEEECCCCCCCCCCEEEE
RLDRLGDALAAGETPRAGDRPVTLERPACATFAMPDAATSAAE
EHHHHCCHHHCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
PVALLPDRALVTVTGPDATTLLQGVLTCNVETLRPGEARLGALLTPQGKILFDFLISRI
CEEECCCCEEEEEECCCHHHHHHHHHHCCCEECCCCCHHHCEEECCCCHHHHHHHHHHC
PDGFRFDVLADRAADLAKRLTLYRLRAQATIAADPTVAVAAAWAGATPPAAEAVADTRAV
CCCCEEHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEHHCCCCCCHHHHHHHHHHH
DLGARLYAAAGAFSADAAEADYHAHRIALGVPEGGRDFAFGDAFPHEALMDQLGGVDFRK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHH
GCYVGQEVVSRMQHRGTARTRILAAAYPDAAPAPGTEITAGGKVLGTAGSAAGNRGLATI
CCHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCEEECCCEEEECCCCCCCCCCEEEE
RLDRLGDALAAGETPRAGDRPVTLERPACATFAMPDAATSAAE
EHHHHCCHHHCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA