| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is hppA [H]
Identifier: 170750373
GI number: 170750373
Start: 4228890
End: 4231034
Strand: Reverse
Name: hppA [H]
Synonym: Mrad2831_3976
Alternate gene names: 170750373
Gene position: 4231034-4228890 (Counterclockwise)
Preceding gene: 170750375
Following gene: 170750372
Centisome position: 69.61
GC content: 69.65
Gene sequence:
>2145_bases ATGATTCCCTTGGTCCTGATCATCGCGGGCGGGCTCTGCGCCGTCGCCTACGGCATCGTCACGATCCTCGACGTGATGCG GCGCGACGCCGGCACGCAGCGCATGCAGGAGATCGCCGCCGCCATCGCCGAGGGCGCGCAGGCCTATCTCCGCCGGCAGT ACACGACGATCGGCCTCGTCGGCGTCGTCCTGTTCGTCCTCCTCGCCGTCTTCCTCGGGATCAAGGTCGCGGTCGGCTTC CTGATCGGCGCCGTGCTGTCGGGCGCGGCCGGCTTCATCGGCATGAACGTCTCGGTGCGGGCCAATGTCCGCACCGCCCA GGCCGCCTCGACCTCGCTGGGCGGCGGCCTCGACGTCGCCTTCAAGTCGGGGGCGGTGACCGGCATGCTGGTCGCGGGCC TCGCGCTCCTCGGCGTCGCCCTCTACTACCTGTTCCTCACCCGCGCGGCCCATCTCGAGCCGTCGAGCCGCGAGGTGATC GACGCCCTCGTGGCGCTGGGCTTCGGCGCCTCGCTGATCTCGATCTTCGCCCGCCTCGGCGGCGGCATCTTCACCAAGGG GGCCGATGTCGGCGGCGACCTCGTCGGCAAGGTCGAGGCCGGCATCCCGGAGGACGATCCGCGCAACCCCGCCACCATCG CCGACAACGTCGGTGACAATGTCGGCGACTGCGCCGGCATGGCGGCCGACCTGTTCGAGACCTACGCGGTGACGGTCGTC GCCACGATGGTGCTGGCCGCGATCTTCTTCTCGGGCGCGGGCGGCAGTGACCGAAACGTCCTCGAGCCGATGATGCTGTA CCCGCTCGCCATCGGCTCGGCCTGCATCCTCACCTCCATCGCCGGCACCTACGCGGTGCGGCTCGGCGCCAACCAGTCGA TCATGGGCGCCCTCTACAAGGGGCTGATCGCCGCCGGCGTGCTCTCCATCGCGGCGATCGCGGCGGTCAACATGACCCTG TTCGGCGGCTTCTCGACGAGCTTCACCACCTCCACCGGCCTGACCTTCACGTCGGGCGCCCTGTTCGGCTGCGCGGTGAT CGGGCTCGCCATCACGGCGCTGATCGTGGTGATCACCGAGTACTACACGGGCACCAACTTCCGCCCGGTGAAGTCGATCG CCGACGCGTCGGTGACCGGGCACGGCACCAACGTGATCCAGGGGCTGGCGATCTCGCTCGAATCGACCGCGCTGCCGGCC ATCGTGATCGTGGCGGGCATCATCAGCACCTACGCGCTCGCCGGCCTGTTCGGCATCGCCATCGCGGTCACCGCCATGCT GGCGCTGGCCGGCTTCATCGTCGCCCTCGACGCGTTCGGACCCGTCACCGACAATGCCGGCGGCATCGCCGAGATGGCGG GCCTGCCCGCCGAGGTGCGCAAGTCGACCGACGCCCTCGACGCGGTCGGCAACACCACCAAGGCGGTGACCAAGGGCTAC GCGATCGGCTCGGCGGGCCTCGGCGCGCTGGTGCTGTTCGCCGCCTACACGTCGGACCTGAACTACTTCATCGCCCATGC GAGCCCGACGCAGTACCGCTTCTTCCAGGGGGTCAGCGTCGATTTCTCGCTCTCCAACCCGTACGTGGTGGTCGGGCTGC TGCTCGGCGGCCTGATCCCGTTCCTGTTCGCCGGCATCGCCATGACGGCGGTCGGGCGCGCGGCGGGCGCGGTGGTCGAG GAGGTCCGGCGCCAGTTCCGGGCCAAGCCCGGGATCATGCAGGGGACCGACCGGCCGGATTACGGGCGGGCGGTGGACAT GCTGACCCGCGCGGCGATCAAGGAGATGATCGTCCCCTCGCTGCTGCCGGTCCTGTCGCCGGTGGTGCTGTTCTTCGTGA TCCAGTTCATCGCCGGGAAGAGCCAGGCCTTCGCCACCGTGGGCGCGAGCCTGCTCGGCGTGATCCTCACCGGGCTCTAC GTGGCGATCTCGATGACCTCGGGCGGCGGCGCCTGGGACAACGCCAAGAAGTACATCGAGGACGGCCACCACGGCGGCAA GGGGTCCGAGGCCCACAAGGCGGCGGTGACCGGCGACACGGTCGGCGACCCCTACAAGGACACCGCCGGTCCGGCGGTGA ACCCGGCGATCAAGATCACCAACATCATCGCCCTCCTGCTGCTCGCCGTGCTGGCGCATAGCTGA
Upstream 100 bases:
>100_bases AAGCCCCGGATCCGAGCACCGCGTCCCATGGCCGTCGTCCGGCGGCCAAGCTCGACAATCACAAGCCCACGCCAGGCACG ATAATAACAAGGACGGTCGA
Downstream 100 bases:
>100_bases GTTCCGCGGGGCTGGGGCGCGTCGACGGGGCCGGGCTCTTCGCAGAGCCCGGCCCTTCCCGTCTCGCCGTGTGCGTACCC GCACGCGACGGTCAGTCCTG
Product: membrane-bound proton-translocating pyrophosphatase
Products: NA
Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]
Number of amino acids: Translated: 714; Mature: 714
Protein sequence:
>714_residues MIPLVLIIAGGLCAVAYGIVTILDVMRRDAGTQRMQEIAAAIAEGAQAYLRRQYTTIGLVGVVLFVLLAVFLGIKVAVGF LIGAVLSGAAGFIGMNVSVRANVRTAQAASTSLGGGLDVAFKSGAVTGMLVAGLALLGVALYYLFLTRAAHLEPSSREVI DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFSGAGGSDRNVLEPMMLYPLAIGSACILTSIAGTYAVRLGANQSIMGALYKGLIAAGVLSIAAIAAVNMTL FGGFSTSFTTSTGLTFTSGALFGCAVIGLAITALIVVITEYYTGTNFRPVKSIADASVTGHGTNVIQGLAISLESTALPA IVIVAGIISTYALAGLFGIAIAVTAMLALAGFIVALDAFGPVTDNAGGIAEMAGLPAEVRKSTDALDAVGNTTKAVTKGY AIGSAGLGALVLFAAYTSDLNYFIAHASPTQYRFFQGVSVDFSLSNPYVVVGLLLGGLIPFLFAGIAMTAVGRAAGAVVE EVRRQFRAKPGIMQGTDRPDYGRAVDMLTRAAIKEMIVPSLLPVLSPVVLFFVIQFIAGKSQAFATVGASLLGVILTGLY VAISMTSGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPAIKITNIIALLLLAVLAHS
Sequences:
>Translated_714_residues MIPLVLIIAGGLCAVAYGIVTILDVMRRDAGTQRMQEIAAAIAEGAQAYLRRQYTTIGLVGVVLFVLLAVFLGIKVAVGF LIGAVLSGAAGFIGMNVSVRANVRTAQAASTSLGGGLDVAFKSGAVTGMLVAGLALLGVALYYLFLTRAAHLEPSSREVI DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFSGAGGSDRNVLEPMMLYPLAIGSACILTSIAGTYAVRLGANQSIMGALYKGLIAAGVLSIAAIAAVNMTL FGGFSTSFTTSTGLTFTSGALFGCAVIGLAITALIVVITEYYTGTNFRPVKSIADASVTGHGTNVIQGLAISLESTALPA IVIVAGIISTYALAGLFGIAIAVTAMLALAGFIVALDAFGPVTDNAGGIAEMAGLPAEVRKSTDALDAVGNTTKAVTKGY AIGSAGLGALVLFAAYTSDLNYFIAHASPTQYRFFQGVSVDFSLSNPYVVVGLLLGGLIPFLFAGIAMTAVGRAAGAVVE EVRRQFRAKPGIMQGTDRPDYGRAVDMLTRAAIKEMIVPSLLPVLSPVVLFFVIQFIAGKSQAFATVGASLLGVILTGLY VAISMTSGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPAIKITNIIALLLLAVLAHS >Mature_714_residues MIPLVLIIAGGLCAVAYGIVTILDVMRRDAGTQRMQEIAAAIAEGAQAYLRRQYTTIGLVGVVLFVLLAVFLGIKVAVGF LIGAVLSGAAGFIGMNVSVRANVRTAQAASTSLGGGLDVAFKSGAVTGMLVAGLALLGVALYYLFLTRAAHLEPSSREVI DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV ATMVLAAIFFSGAGGSDRNVLEPMMLYPLAIGSACILTSIAGTYAVRLGANQSIMGALYKGLIAAGVLSIAAIAAVNMTL FGGFSTSFTTSTGLTFTSGALFGCAVIGLAITALIVVITEYYTGTNFRPVKSIADASVTGHGTNVIQGLAISLESTALPA IVIVAGIISTYALAGLFGIAIAVTAMLALAGFIVALDAFGPVTDNAGGIAEMAGLPAEVRKSTDALDAVGNTTKAVTKGY AIGSAGLGALVLFAAYTSDLNYFIAHASPTQYRFFQGVSVDFSLSNPYVVVGLLLGGLIPFLFAGIAMTAVGRAAGAVVE EVRRQFRAKPGIMQGTDRPDYGRAVDMLTRAAIKEMIVPSLLPVLSPVVLFFVIQFIAGKSQAFATVGASLLGVILTGLY VAISMTSGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPAIKITNIIALLLLAVLAHS
Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]
COG id: COG3808
COG function: function code C; Inorganic pyrophosphatase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004131 [H]
Pfam domain/function: PF03030 H_PPase [H]
EC number: =3.6.1.1 [H]
Molecular weight: Translated: 72616; Mature: 72616
Theoretical pI: Translated: 6.41; Mature: 6.41
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIPLVLIIAGGLCAVAYGIVTILDVMRRDAGTQRMQEIAAAIAEGAQAYLRRQYTTIGLV CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVVLFVLLAVFLGIKVAVGFLIGAVLSGAAGFIGMNVSVRANVRTAQAASTSLGGGLDVA HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEEECCCHHHHHHCCCCCCCEEH FKSGAVTGMLVAGLALLGVALYYLFLTRAAHLEPSSREVIDALVALGFGASLISIFARLG CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH ATMVLAAIFFSGAGGSDRNVLEPMMLYPLAIGSACILTSIAGTYAVRLGANQSIMGALYK HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHH GLIAAGVLSIAAIAAVNMTLFGGFSTSFTTSTGLTFTSGALFGCAVIGLAITALIVVITE HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH YYTGTNFRPVKSIADASVTGHGTNVIQGLAISLESTALPAIVIVAGIISTYALAGLFGIA HHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IAVTAMLALAGFIVALDAFGPVTDNAGGIAEMAGLPAEVRKSTDALDAVGNTTKAVTKGY HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCC AIGSAGLGALVLFAAYTSDLNYFIAHASPTQYRFFQGVSVDFSLSNPYVVVGLLLGGLIP CCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHH FLFAGIAMTAVGRAAGAVVEEVRRQFRAKPGIMQGTDRPDYGRAVDMLTRAAIKEMIVPS HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH LLPVLSPVVLFFVIQFIAGKSQAFATVGASLLGVILTGLYVAISMTSGGGAWDNAKKYIE HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH DGHHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPAIKITNIIALLLLAVLAHS CCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MIPLVLIIAGGLCAVAYGIVTILDVMRRDAGTQRMQEIAAAIAEGAQAYLRRQYTTIGLV CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVVLFVLLAVFLGIKVAVGFLIGAVLSGAAGFIGMNVSVRANVRTAQAASTSLGGGLDVA HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCEEEEECCCHHHHHHCCCCCCCEEH FKSGAVTGMLVAGLALLGVALYYLFLTRAAHLEPSSREVIDALVALGFGASLISIFARLG CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH ATMVLAAIFFSGAGGSDRNVLEPMMLYPLAIGSACILTSIAGTYAVRLGANQSIMGALYK HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHH GLIAAGVLSIAAIAAVNMTLFGGFSTSFTTSTGLTFTSGALFGCAVIGLAITALIVVITE HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH YYTGTNFRPVKSIADASVTGHGTNVIQGLAISLESTALPAIVIVAGIISTYALAGLFGIA HHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IAVTAMLALAGFIVALDAFGPVTDNAGGIAEMAGLPAEVRKSTDALDAVGNTTKAVTKGY HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCC AIGSAGLGALVLFAAYTSDLNYFIAHASPTQYRFFQGVSVDFSLSNPYVVVGLLLGGLIP CCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHH FLFAGIAMTAVGRAAGAVVEEVRRQFRAKPGIMQGTDRPDYGRAVDMLTRAAIKEMIVPS HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH LLPVLSPVVLFFVIQFIAGKSQAFATVGASLLGVILTGLYVAISMTSGGGAWDNAKKYIE HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH DGHHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPAIKITNIIALLLLAVLAHS CCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12597275 [H]