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The map label for this gene is yiaY [H]

Identifier: 170750185

GI number: 170750185

Start: 4028261

End: 4029424

Strand: Direct

Name: yiaY [H]

Synonym: Mrad2831_3787

Alternate gene names: 170750185

Gene position: 4028261-4029424 (Clockwise)

Preceding gene: 170750184

Following gene: 170750188

Centisome position: 66.28

GC content: 73.97

Gene sequence:

>1164_bases
ATGGTCGCCTCGATCGCCCTGCCCCGGCTGATGCGCGTCGGCGCCGGCGCCTCGCGGCTCCTGCCGGAGGTGCTCGGCCA
GCTCGGCCTGTCGCGCCCCTTCGTGGTCACCGACCCCTACCTCGCCGGCAGCGGCCGCACCGACACGCTGCTCGAGCGGC
TCACCGCGGCGGGCGCGCGTGCCACGATCTTCTCCGAGACCGTGCCGGACCCGACCGTCGCCTCCGTGGAGGCGGCGCTG
GCGGCCCTCCAGGCGGGCGACTTCGACTGCGTGGTCGGCTTCGGCGGCGGCAGCCCGATGGACACCGCCAAGGCGGTGGC
GGTGCTCGCCCGCCACGGCGGCCACATGCGCGACTACAAGGCGCCCCGCCAGCAGGACGAGTCCGGCCTGCCGATCGTGG
CGATCCCGACCACCGCCGGCACCGGCTCGGAGGCGACCCGCTTCACCATCGTGACCGACGAGGCCTCGGACGAGAAGATG
CTCTGCATCGGCCTCGCCTACCTGCCGGTCGCGGCCCTGGTCGATTACGAGCTGACGCTCACCAAGCCGAAGCGGCTCAC
GGCGGACACCGGCATCGACGCCCTGACCCACGCGATCGAGGCCTACGTCTCGCGCAAGTCGAACCTGTTCTCGGACGGGC
TGGCGCTGCAGGCGATGCGGCTGATCGCCCCGAACCTGCGCCGGGTCTGGACCGATCCCGGCGACCGGGCGGCGCGCGAG
GCGATGATGCTCGGCGCCACCCAGGCGGGCATCGCGTTCTCGAACGCCTCGGTGGCGCTGGTCCACGGCATGAGCCGGCC
GATCGGCGCGCATTTCCACGTGGCGCACGGGCTCTCGAACGCGATGCTGCTGCCGGCGGTGACGGCCTTCTCGGCCCCGG
CCGCCGTCGACCGGTACGCCGCCTGTGCCCGCGCCATGAAGATCGCCGGCCCCGACACCGACGATCGCTCGGCGGTGTCG
GCCCTGGTGGCCGAGCTCGAGGCACTGAACGACGACCTCGACGTGCCGGGGCCGCGGGAATACGGGATCGACCCGGCCCG
CTGGGAGGCGCTGCTGCCCACCATGGCGGCCCAGGCGCTGGCCTCCGGCTCCCCGGCCAACAACCCGGTGGAGCCCACCG
CCGACGAGATCGTGGCGCTGTACCGGCGCGTCTGGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCCGGCAGTGTAAGCGCCGGCAGTTTCGCCCGGCGCGCGCAGGTCCTAAGATCGCCGTCCCGGCGGACCAGCAGAGGCGC
CGGGAGGGAGAAGCAACAGA

Downstream 100 bases:

>100_bases
CGACGGCGTCCTATCGGCGGCCCGCGAGCGCCGTCGTCTCCGCGAGCGGAGCGAGACGCCTGAGCAGCGCCACGCTCTCC
GAGGCCGCGTAGCGCTCAGT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MVASIALPRLMRVGAGASRLLPEVLGQLGLSRPFVVTDPYLAGSGRTDTLLERLTAAGARATIFSETVPDPTVASVEAAL
AALQAGDFDCVVGFGGGSPMDTAKAVAVLARHGGHMRDYKAPRQQDESGLPIVAIPTTAGTGSEATRFTIVTDEASDEKM
LCIGLAYLPVAALVDYELTLTKPKRLTADTGIDALTHAIEAYVSRKSNLFSDGLALQAMRLIAPNLRRVWTDPGDRAARE
AMMLGATQAGIAFSNASVALVHGMSRPIGAHFHVAHGLSNAMLLPAVTAFSAPAAVDRYAACARAMKIAGPDTDDRSAVS
ALVAELEALNDDLDVPGPREYGIDPARWEALLPTMAAQALASGSPANNPVEPTADEIVALYRRVWAG

Sequences:

>Translated_387_residues
MVASIALPRLMRVGAGASRLLPEVLGQLGLSRPFVVTDPYLAGSGRTDTLLERLTAAGARATIFSETVPDPTVASVEAAL
AALQAGDFDCVVGFGGGSPMDTAKAVAVLARHGGHMRDYKAPRQQDESGLPIVAIPTTAGTGSEATRFTIVTDEASDEKM
LCIGLAYLPVAALVDYELTLTKPKRLTADTGIDALTHAIEAYVSRKSNLFSDGLALQAMRLIAPNLRRVWTDPGDRAARE
AMMLGATQAGIAFSNASVALVHGMSRPIGAHFHVAHGLSNAMLLPAVTAFSAPAAVDRYAACARAMKIAGPDTDDRSAVS
ALVAELEALNDDLDVPGPREYGIDPARWEALLPTMAAQALASGSPANNPVEPTADEIVALYRRVWAG
>Mature_387_residues
MVASIALPRLMRVGAGASRLLPEVLGQLGLSRPFVVTDPYLAGSGRTDTLLERLTAAGARATIFSETVPDPTVASVEAAL
AALQAGDFDCVVGFGGGSPMDTAKAVAVLARHGGHMRDYKAPRQQDESGLPIVAIPTTAGTGSEATRFTIVTDEASDEKM
LCIGLAYLPVAALVDYELTLTKPKRLTADTGIDALTHAIEAYVSRKSNLFSDGLALQAMRLIAPNLRRVWTDPGDRAARE
AMMLGATQAGIAFSNASVALVHGMSRPIGAHFHVAHGLSNAMLLPAVTAFSAPAAVDRYAACARAMKIAGPDTDDRSAVS
ALVAELEALNDDLDVPGPREYGIDPARWEALLPTMAAQALASGSPANNPVEPTADEIVALYRRVWAG

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=341, Percent_Identity=32.258064516129, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI48994951, Length=377, Percent_Identity=37.1352785145889, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789163, Length=388, Percent_Identity=34.5360824742268, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI87082107, Length=380, Percent_Identity=36.3157894736842, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787493, Length=397, Percent_Identity=34.5088161209068, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789386, Length=340, Percent_Identity=23.2352941176471, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537053, Length=385, Percent_Identity=27.7922077922078, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=390, Percent_Identity=34.8717948717949, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24657991, Length=334, Percent_Identity=29.940119760479, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40420; Mature: 40420

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVASIALPRLMRVGAGASRLLPEVLGQLGLSRPFVVTDPYLAGSGRTDTLLERLTAAGAR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCEECCCCCHHHHHHHHHHCCCH
ATIFSETVPDPTVASVEAALAALQAGDFDCVVGFGGGSPMDTAKAVAVLARHGGHMRDYK
HEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
APRQQDESGLPIVAIPTTAGTGSEATRFTIVTDEASDEKMLCIGLAYLPVAALVDYELTL
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHCCEEEE
TKPKRLTADTGIDALTHAIEAYVSRKSNLFSDGLALQAMRLIAPNLRRVWTDPGDRAARE
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCHHHHHCCCCCHHHHHH
AMMLGATQAGIAFSNASVALVHGMSRPIGAHFHVAHGLSNAMLLPAVTAFSAPAAVDRYA
HHHHCCHHHCEEECCCCEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHH
ACARAMKIAGPDTDDRSAVSALVAELEALNDDLDVPGPREYGIDPARWEALLPTMAAQAL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ASGSPANNPVEPTADEIVALYRRVWAG
HCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVASIALPRLMRVGAGASRLLPEVLGQLGLSRPFVVTDPYLAGSGRTDTLLERLTAAGAR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCEECCCCCHHHHHHHHHHCCCH
ATIFSETVPDPTVASVEAALAALQAGDFDCVVGFGGGSPMDTAKAVAVLARHGGHMRDYK
HEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
APRQQDESGLPIVAIPTTAGTGSEATRFTIVTDEASDEKMLCIGLAYLPVAALVDYELTL
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHCCEEEE
TKPKRLTADTGIDALTHAIEAYVSRKSNLFSDGLALQAMRLIAPNLRRVWTDPGDRAARE
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCHHHHHCCCCCHHHHHH
AMMLGATQAGIAFSNASVALVHGMSRPIGAHFHVAHGLSNAMLLPAVTAFSAPAAVDRYA
HHHHCCHHHCEEECCCCEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHH
ACARAMKIAGPDTDDRSAVSALVAELEALNDDLDVPGPREYGIDPARWEALLPTMAAQAL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ASGSPANNPVEPTADEIVALYRRVWAG
HCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]