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The map label for this gene is plsC [C]

Identifier: 170750145

GI number: 170750145

Start: 3986644

End: 3987378

Strand: Direct

Name: plsC [C]

Synonym: Mrad2831_3747

Alternate gene names: 170750145

Gene position: 3986644-3987378 (Clockwise)

Preceding gene: 170750142

Following gene: 170750148

Centisome position: 65.59

GC content: 74.15

Gene sequence:

>735_bases
ATGGCACACGCCCGCTCGCTCCTGTTCGCCGTCTACTGGGCCGCCTGGACGACCCTGTTCCTCGCGCCGCTGGCGATCTT
CCTCCTGTCCGGATCGCCGCAGCGGCCGATCCGCCGGGCGACGCGGCTCTGGGCGCGCGGGATCCTCGGCGGGCTGCGGC
GGATCGTCGGGCTGCGCTACGTCGAGGAGGGCCGCCAGCACCTGCCGGACGAGCCCTGCCTGATCGTCGCCAACCACCAG
TCGACCTGGGAGACCCTGGCCTTCCTGGTCCTGGTGCCGGACGTGGCGATCGTCGCGAAGCGGGAACTGCTGGCGATCCC
GGTGGTCGGCTGGTTCCTCCGCCGCTCGCCGATGATCGTCATCGACCGGGCCAAGGGCACCCAGGCCCTGCGCACCATGA
TCGACGGCGGTCGGGAGGCGGTCGCGGCGGGCCGGTCGGTGCTGATCTTCCCCGAGGGCACCCGCGGCGCGATCGGCGAG
CCGCTGCGCTTCAAGCGCGGCGTCGAGTTGCTCTACGGCCGGCTCGGCCTGCCGGTGGTGCCGGTGGCGCTCAACTCCGG
CCTGTTCTGGCCCGGGGGCGCGGCGACCCGGTCCGGCACGGTGGTGGTGAGCTACCTCGCCGCCCTGGCTCCCGGCCTGC
CGACCGCGGAGTTCCTGCACGGGACGGAAGGCGCGATCGATCGGGAGTTGAACCGGTGGCGGCCCGGCGGCGCGGCCGGG
CTCGGCGCCTCCTGA

Upstream 100 bases:

>100_bases
AGTCCGCTCACCGTTTGCCGGGCGAAAGGCCGTGCGCGATCGACCGGCAGGCGCTATGCCCGGGCCCTGCCCTGTCCCGG
GCCCCTCGTCGAGGCCCGCC

Downstream 100 bases:

>100_bases
GGGGCGCCCCCGTCACTTCTGCGATTGCTGGATCTGCTGCTGCATCGCCTTGTCCTCGGAGCGCCCGTAATTGATGAAGA
ACAGGCTGCCGTCGACGCTC

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAHARSLLFAVYWAAWTTLFLAPLAIFLLSGSPQRPIRRATRLWARGILGGLRRIVGLRYVEEGRQHLPDEPCLIVANHQ
STWETLAFLVLVPDVAIVAKRELLAIPVVGWFLRRSPMIVIDRAKGTQALRTMIDGGREAVAAGRSVLIFPEGTRGAIGE
PLRFKRGVELLYGRLGLPVVPVALNSGLFWPGGAATRSGTVVVSYLAALAPGLPTAEFLHGTEGAIDRELNRWRPGGAAG
LGAS

Sequences:

>Translated_244_residues
MAHARSLLFAVYWAAWTTLFLAPLAIFLLSGSPQRPIRRATRLWARGILGGLRRIVGLRYVEEGRQHLPDEPCLIVANHQ
STWETLAFLVLVPDVAIVAKRELLAIPVVGWFLRRSPMIVIDRAKGTQALRTMIDGGREAVAAGRSVLIFPEGTRGAIGE
PLRFKRGVELLYGRLGLPVVPVALNSGLFWPGGAATRSGTVVVSYLAALAPGLPTAEFLHGTEGAIDRELNRWRPGGAAG
LGAS
>Mature_243_residues
AHARSLLFAVYWAAWTTLFLAPLAIFLLSGSPQRPIRRATRLWARGILGGLRRIVGLRYVEEGRQHLPDEPCLIVANHQS
TWETLAFLVLVPDVAIVAKRELLAIPVVGWFLRRSPMIVIDRAKGTQALRTMIDGGREAVAAGRSVLIFPEGTRGAIGEP
LRFKRGVELLYGRLGLPVVPVALNSGLFWPGGAATRSGTVVVSYLAALAPGLPTAEFLHGTEGAIDRELNRWRPGGAAGL
GAS

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=172, Percent_Identity=33.1395348837209, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI5453718, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15100175, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568319, Length=167, Percent_Identity=30.5389221556886, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=173, Percent_Identity=29.4797687861272, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641614, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641612, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 26353; Mature: 26222

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHARSLLFAVYWAAWTTLFLAPLAIFLLSGSPQRPIRRATRLWARGILGGLRRIVGLRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEGRQHLPDEPCLIVANHQSTWETLAFLVLVPDVAIVAKRELLAIPVVGWFLRRSPMIV
HHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
IDRAKGTQALRTMIDGGREAVAAGRSVLIFPEGTRGAIGEPLRFKRGVELLYGRLGLPVV
EECCCCHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEE
PVALNSGLFWPGGAATRSGTVVVSYLAALAPGLPTAEFLHGTEGAIDRELNRWRPGGAAG
EHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCC
LGAS
CCCC
>Mature Secondary Structure 
AHARSLLFAVYWAAWTTLFLAPLAIFLLSGSPQRPIRRATRLWARGILGGLRRIVGLRY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEGRQHLPDEPCLIVANHQSTWETLAFLVLVPDVAIVAKRELLAIPVVGWFLRRSPMIV
HHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
IDRAKGTQALRTMIDGGREAVAAGRSVLIFPEGTRGAIGEPLRFKRGVELLYGRLGLPVV
EECCCCHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEE
PVALNSGLFWPGGAATRSGTVVVSYLAALAPGLPTAEFLHGTEGAIDRELNRWRPGGAAG
EHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCC
LGAS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA