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The map label for this gene is fchA [H]

Identifier: 170750066

GI number: 170750066

Start: 3898846

End: 3899487

Strand: Reverse

Name: fchA [H]

Synonym: Mrad2831_3667

Alternate gene names: 170750066

Gene position: 3899487-3898846 (Counterclockwise)

Preceding gene: 170750067

Following gene: 170750065

Centisome position: 64.16

GC content: 69.78

Gene sequence:

>642_bases
GTGACCGAGACGCATCGCCCCGAGGGCGACAGCATCGAGAAGTTCCTGACGGAGCTGGCGAGCGCCGCCCCGACCCCCGG
GGGCGGCGGCGCGGCGGCGATCTCCGGCGCCATGGGCGCGGCCCTGGTGTCGATGGTCTGCAACCTCACCATCGGCAAGA
AGAAGTACGTCGAGGTCGAGGCCGAGCTGAAGGACGTCCTGGCCAAGTCCGAGGGCCTGCGGGTCGTGCTGACCGGCATG
ATCGGCGAGGACGTCCAGGCCTTCGACGCCGTGATGGGCGCTTACGGGATGCCCAAGAACACCGACGACGAGAAGGCGGC
CCGCGCGGAGAGGATCCAGGCGGCGCTCAAGACCGCCTGCGACGTGCCGCTCGCCTGCTGCCGGGCCTGCCGCGCGGTGA
TCGACCTCGCGGCGATCACCGCCGACAAGGGCAATCTCAACGTCGTGTCGGACGCCGGCGTGGCGGTGCTCTCCGCCTAT
GCCGGCCTGCGCAGCGCGGCGCTCAACGTCTACGTCAACGCCAAGGGTCTCGAGGACCGCGACTTCGCCGACGAGCGGCT
GAAGGAGCTCGAGGAGCTGCTCGGCGAGGCCGGTGCGCTGACCGAGAAGGTCTACGGGATCGTGAAGGCCAAGGTGAACT
GA

Upstream 100 bases:

>100_bases
CACCGGGCCTGCGTCGGCCAGCTCTTCGAGAGCACCGACAAGGTGCTCGACGCCGAGGAGATCTACGCCCTCGCCAAGAC
GATGGCTTGAGGAGGCGCCG

Downstream 100 bases:

>100_bases
GAGGGCCGCCCTGCGTCCTTCGCAGGGGGAGGGCGCGTGCCCGCTGCGGCGGCGCCAAGCTGGACAGCGTGTCCGGTTGA
TCCCGTCGACGCCGCCGTCT

Product: formiminotransferase-cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTETHRPEGDSIEKFLTELASAAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVEAELKDVLAKSEGLRVVLTGM
IGEDVQAFDAVMGAYGMPKNTDDEKAARAERIQAALKTACDVPLACCRACRAVIDLAAITADKGNLNVVSDAGVAVLSAY
AGLRSAALNVYVNAKGLEDRDFADERLKELEELLGEAGALTEKVYGIVKAKVN

Sequences:

>Translated_213_residues
MTETHRPEGDSIEKFLTELASAAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVEAELKDVLAKSEGLRVVLTGM
IGEDVQAFDAVMGAYGMPKNTDDEKAARAERIQAALKTACDVPLACCRACRAVIDLAAITADKGNLNVVSDAGVAVLSAY
AGLRSAALNVYVNAKGLEDRDFADERLKELEELLGEAGALTEKVYGIVKAKVN
>Mature_212_residues
TETHRPEGDSIEKFLTELASAAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVEAELKDVLAKSEGLRVVLTGMI
GEDVQAFDAVMGAYGMPKNTDDEKAARAERIQAALKTACDVPLACCRACRAVIDLAAITADKGNLNVVSDAGVAVLSAYA
GLRSAALNVYVNAKGLEDRDFADERLKELEELLGEAGALTEKVYGIVKAKVN

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=156, Percent_Identity=29.4871794871795, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI11140815, Length=156, Percent_Identity=29.4871794871795, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22148; Mature: 22016

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETHRPEGDSIEKFLTELASAAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVE
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEHH
AELKDVLAKSEGLRVVLTGMIGEDVQAFDAVMGAYGMPKNTDDEKAARAERIQAALKTAC
HHHHHHHHCCCCCEEEEECHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
DVPLACCRACRAVIDLAAITADKGNLNVVSDAGVAVLSAYAGLRSAALNVYVNAKGLEDR
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHEEEEEECCCCCCC
DFADERLKELEELLGEAGALTEKVYGIVKAKVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TETHRPEGDSIEKFLTELASAAPTPGGGGAAAISGAMGAALVSMVCNLTIGKKKYVEVE
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEHH
AELKDVLAKSEGLRVVLTGMIGEDVQAFDAVMGAYGMPKNTDDEKAARAERIQAALKTAC
HHHHHHHHCCCCCEEEEECHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
DVPLACCRACRAVIDLAAITADKGNLNVVSDAGVAVLSAYAGLRSAALNVYVNAKGLEDR
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHEEEEEECCCCCCC
DFADERLKELEELLGEAGALTEKVYGIVKAKVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]