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The map label for this gene is lepB [H]

Identifier: 170749856

GI number: 170749856

Start: 3670741

End: 3671556

Strand: Reverse

Name: lepB [H]

Synonym: Mrad2831_3456

Alternate gene names: 170749856

Gene position: 3671556-3670741 (Counterclockwise)

Preceding gene: 170749857

Following gene: 170749855

Centisome position: 60.41

GC content: 63.97

Gene sequence:

>816_bases
ATGCACCTCAACCGAAGACGGAACGCGCGCGTGGATTACGACGGCAAGCCGCTCAGGAAACCCGCCGAGACCGGCACCTG
GGCCAGCATCCGCGAGACGCTGAAGGTCGGCATCCAGGCGCTGCTGATCGCCCTGGTGGTGCGGACGCTCCTGTTCCAGC
CGTTCAACATCCCTTCGGGCTCGCTGGTGCCGACGCTGCTGATCGGTGACTACCTGTTCGTGTCGAAATATTCCTACGGC
TATTCCAAGTACTCGCTGCCTCTCTCGGAATACATTCCGATCCAGGCCGACGGCCGGATCTGGGGAGCCGACCCGAAGCG
CGGCGACATCGCGGTGTTCAAGCTGCCCAAGGACAACTCGACCGACTACATCAAGCGCGTGATCGGCCTGCCGGGCGACA
AGATCCAGATGATCGACGGCGTGCTCAACATCAACGGCAAGGCGGTCAAGCGCGAGCGGATCGCCGACTACGAGACCACC
GACCCCTACGGCCAGCCGACCAAGGTGCCCCAGTACCTGGAGACCCTGCCCAACGGCGTGGTCCACCGGGTGATCGAGCG
CGACGGCGACAACGGGTTCTGGGACAAGACCGAGCTGTACACGGTCCCGCCCGGTCACTTTTTCATGATGGGCGACAACC
GCGACAACTCCACCGATTCGCGCGATCTCGCCAATGTCGGCTACGTGCCCTTCGCCAACCTGGTCGGGCGCGCCGAGATG
ATCTTCTTCTCGATCGACGAGGGCACGCCGGCGTGGCAGGTCTGGAACTGGCCGGCCCACGTGCGCTGGTCGCGCCTGTT
CACGACGATCCATTGA

Upstream 100 bases:

>100_bases
CTAGACCGCCGGTCACGGCGGACACGATTGCGGCGCATTCCTCGGGACAACCGCACATCAGGCCGCGCGCGGCGGGGCCG
CGCCCCGCTGAGCGCGGGCG

Downstream 100 bases:

>100_bases
CCGGCCCGGACTTGGACGACGCCGCGCAGCCCCGGGCGAACGCCCGATCCCGGCGGGCCCACAAGCCGCGCCCGCCCCTG
ACCGCCCTCGAGGAGCGGAT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MHLNRRRNARVDYDGKPLRKPAETGTWASIRETLKVGIQALLIALVVRTLLFQPFNIPSGSLVPTLLIGDYLFVSKYSYG
YSKYSLPLSEYIPIQADGRIWGADPKRGDIAVFKLPKDNSTDYIKRVIGLPGDKIQMIDGVLNINGKAVKRERIADYETT
DPYGQPTKVPQYLETLPNGVVHRVIERDGDNGFWDKTELYTVPPGHFFMMGDNRDNSTDSRDLANVGYVPFANLVGRAEM
IFFSIDEGTPAWQVWNWPAHVRWSRLFTTIH

Sequences:

>Translated_271_residues
MHLNRRRNARVDYDGKPLRKPAETGTWASIRETLKVGIQALLIALVVRTLLFQPFNIPSGSLVPTLLIGDYLFVSKYSYG
YSKYSLPLSEYIPIQADGRIWGADPKRGDIAVFKLPKDNSTDYIKRVIGLPGDKIQMIDGVLNINGKAVKRERIADYETT
DPYGQPTKVPQYLETLPNGVVHRVIERDGDNGFWDKTELYTVPPGHFFMMGDNRDNSTDSRDLANVGYVPFANLVGRAEM
IFFSIDEGTPAWQVWNWPAHVRWSRLFTTIH
>Mature_271_residues
MHLNRRRNARVDYDGKPLRKPAETGTWASIRETLKVGIQALLIALVVRTLLFQPFNIPSGSLVPTLLIGDYLFVSKYSYG
YSKYSLPLSEYIPIQADGRIWGADPKRGDIAVFKLPKDNSTDYIKRVIGLPGDKIQMIDGVLNINGKAVKRERIADYETT
DPYGQPTKVPQYLETLPNGVVHRVIERDGDNGFWDKTELYTVPPGHFFMMGDNRDNSTDSRDLANVGYVPFANLVGRAEM
IFFSIDEGTPAWQVWNWPAHVRWSRLFTTIH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=295, Percent_Identity=37.2881355932203, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30791; Mature: 30791

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLNRRRNARVDYDGKPLRKPAETGTWASIRETLKVGIQALLIALVVRTLLFQPFNIPSG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SLVPTLLIGDYLFVSKYSYGYSKYSLPLSEYIPIQADGRIWGADPKRGDIAVFKLPKDNS
CCHHHHHHHCCCEEECCCCCCEEECCCHHHCCCEEECCEEECCCCCCCCEEEEECCCCCC
TDYIKRVIGLPGDKIQMIDGVLNINGKAVKRERIADYETTDPYGQPTKVPQYLETLPNGV
HHHHHHHHCCCCCCEEEEHHEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHH
VHRVIERDGDNGFWDKTELYTVPPGHFFMMGDNRDNSTDSRDLANVGYVPFANLVGRAEM
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHCCEEE
IFFSIDEGTPAWQVWNWPAHVRWSRLFTTIH
EEEEECCCCCCEEEECCCCHHHHHHHHEECC
>Mature Secondary Structure
MHLNRRRNARVDYDGKPLRKPAETGTWASIRETLKVGIQALLIALVVRTLLFQPFNIPSG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SLVPTLLIGDYLFVSKYSYGYSKYSLPLSEYIPIQADGRIWGADPKRGDIAVFKLPKDNS
CCHHHHHHHCCCEEECCCCCCEEECCCHHHCCCEEECCEEECCCCCCCCEEEEECCCCCC
TDYIKRVIGLPGDKIQMIDGVLNINGKAVKRERIADYETTDPYGQPTKVPQYLETLPNGV
HHHHHHHHCCCCCCEEEEHHEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHH
VHRVIERDGDNGFWDKTELYTVPPGHFFMMGDNRDNSTDSRDLANVGYVPFANLVGRAEM
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHCCEEE
IFFSIDEGTPAWQVWNWPAHVRWSRLFTTIH
EEEEECCCCCCEEEECCCCHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA