BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is exuT [H]

Identifier: 170749813

GI number: 170749813

Start: 3623534

End: 3624829

Strand: Direct

Name: exuT [H]

Synonym: Mrad2831_3412

Alternate gene names: 170749813

Gene position: 3623534-3624829 (Clockwise)

Preceding gene: 170749812

Following gene: 170749814

Centisome position: 59.62

GC content: 69.29

Gene sequence:

>1296_bases
ATGTTCGCCAAGCGTTACAGATTCCTGATCGCGTTCCTGCTGTTCATCGCCGGTATCATCAACTACATGGACCGGGCCGC
GCTCGGCGTCGCCGCGCCCTTCGTCAAGGAGGACCTGAACCTGTCGCCCTCGGAGCTGGGGGTGATCTTCAGCACGTTCT
TCTTCGGCTACGCGCTGTTCGCCTTCGTGGGCGGCCAGCTCGCCGACCGCTACGGGCCGCGCAGCGTCTACAGCTGGGCC
GCCGCCGCGTGGTCGGTCCTGTGCATGCTCACCGGCGCGGTGACCGGCTTCGCCCAGATGTTCGTCGTCCGCGCCCTGTT
CGGCTTCGCCGAGGGTCCGATGAACTCGACCACGAACCGCACCATCACCACGTGGTTCCCCCGCGAGGAGACCGCCCGGA
CCATCGGCTTCACCTTCTCGGGCCAGACGGTGGGCAGCGCCATCGCGGCGCCGGTCGTCGGCCTGCTGGCGATCCAGTAC
GGCTGGCGGGTGGCGTTCGTGGCCATCGGCGCCGTCGGCCTGCTCTGGGTCGTGGCGTGGCGGATGCTCATGACCGACCG
GCCGCAGGACAATCCCCGGGTCGATCCGGAGGAGATCGCCCTCGTGGAGCGGAGCCGGGCCGTCACGCACCTCGCGCCGT
CCGACCATGCCCGGTCGCTCAAGGAATACCTGTTCCTGCCGAGCACCCTGTCGCTCGGGCTCGGCATGTTCGCGGTGAAT
TACACCCTCTACATCTTCCTCTCGTGGCTCCCGAGCTACCTCACCGACGCGCTGCACATGCCGGTGAAGGAGATGGCGCT
GGTCGCCTCGATTCCCTGGGCCTGCGGCTTCGTCGGATACGTCGGCGGGGGCGTGGTGGCGGACTTCGTCTACACGCGCA
TGGGCGACAAGCTCGCCGCGCGGAAGATCACCACGATCGTGCCGCTGGCCGTCGCGGGCGTCGCCCTGCTCGCCGTCAAC
GCCGCGACCAGCACCGCCATGGCGGTCTCGCTCATCGCGCTCGCCGTGCTGATGCTGACCAGCTCGGTGCAATCCTGCTG
GGCGACGATCCACGAGCTGGTGCCCGAGGCGCGGGTCGGCGGCGTCAGCGGCTTCATCCACCTCCTGAGCAACATCTCGG
GCATCATCGGGCCGACCGCCACGGGGCTGGCCGTGCAGTATCTCGGGGGCTACGCCAGCGCCTTCGTGATCGCCGCCCTG
ATCGCGGCGGCCGGCGTCGTCGCGATGGCGATCTTCGTGCGGCGGCCGCGCAACCCGGCGGAAGCCGGTCCCCTCACCGC
GGCCAAGGCCGTCTGA

Upstream 100 bases:

>100_bases
GGAGAGGCGGAGCCGGCGGCGGTCGAACCGTGACCTCTGGCCGCCGGGCCGCACCGAGCAATCAAGAAAAGAAAACCATA
AATATTTCGGAGGATGCCCA

Downstream 100 bases:

>100_bases
CCGAGGCCGTCTGATCAAGGCTGCCCGACCAGGCCGCCGGAATCTGGAGCAGCGTCCCATGAGTGCCGAGACCGTCCCGT
CCAAACCCGTCCTCCTGACC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFAKRYRFLIAFLLFIAGIINYMDRAALGVAAPFVKEDLNLSPSELGVIFSTFFFGYALFAFVGGQLADRYGPRSVYSWA
AAAWSVLCMLTGAVTGFAQMFVVRALFGFAEGPMNSTTNRTITTWFPREETARTIGFTFSGQTVGSAIAAPVVGLLAIQY
GWRVAFVAIGAVGLLWVVAWRMLMTDRPQDNPRVDPEEIALVERSRAVTHLAPSDHARSLKEYLFLPSTLSLGLGMFAVN
YTLYIFLSWLPSYLTDALHMPVKEMALVASIPWACGFVGYVGGGVVADFVYTRMGDKLAARKITTIVPLAVAGVALLAVN
AATSTAMAVSLIALAVLMLTSSVQSCWATIHELVPEARVGGVSGFIHLLSNISGIIGPTATGLAVQYLGGYASAFVIAAL
IAAAGVVAMAIFVRRPRNPAEAGPLTAAKAV

Sequences:

>Translated_431_residues
MFAKRYRFLIAFLLFIAGIINYMDRAALGVAAPFVKEDLNLSPSELGVIFSTFFFGYALFAFVGGQLADRYGPRSVYSWA
AAAWSVLCMLTGAVTGFAQMFVVRALFGFAEGPMNSTTNRTITTWFPREETARTIGFTFSGQTVGSAIAAPVVGLLAIQY
GWRVAFVAIGAVGLLWVVAWRMLMTDRPQDNPRVDPEEIALVERSRAVTHLAPSDHARSLKEYLFLPSTLSLGLGMFAVN
YTLYIFLSWLPSYLTDALHMPVKEMALVASIPWACGFVGYVGGGVVADFVYTRMGDKLAARKITTIVPLAVAGVALLAVN
AATSTAMAVSLIALAVLMLTSSVQSCWATIHELVPEARVGGVSGFIHLLSNISGIIGPTATGLAVQYLGGYASAFVIAAL
IAAAGVVAMAIFVRRPRNPAEAGPLTAAKAV
>Mature_431_residues
MFAKRYRFLIAFLLFIAGIINYMDRAALGVAAPFVKEDLNLSPSELGVIFSTFFFGYALFAFVGGQLADRYGPRSVYSWA
AAAWSVLCMLTGAVTGFAQMFVVRALFGFAEGPMNSTTNRTITTWFPREETARTIGFTFSGQTVGSAIAAPVVGLLAIQY
GWRVAFVAIGAVGLLWVVAWRMLMTDRPQDNPRVDPEEIALVERSRAVTHLAPSDHARSLKEYLFLPSTLSLGLGMFAVN
YTLYIFLSWLPSYLTDALHMPVKEMALVASIPWACGFVGYVGGGVVADFVYTRMGDKLAARKITTIVPLAVAGVALLAVN
AATSTAMAVSLIALAVLMLTSSVQSCWATIHELVPEARVGGVSGFIHLLSNISGIIGPTATGLAVQYLGGYASAFVIAAL
IAAAGVVAMAIFVRRPRNPAEAGPLTAAKAV

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=379, Percent_Identity=24.2744063324538, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI9966811, Length=436, Percent_Identity=23.6238532110092, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI9945322, Length=448, Percent_Identity=22.5446428571429, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI21322234, Length=428, Percent_Identity=22.8971962616822, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI154350196, Length=409, Percent_Identity=22.9828850855746, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI148743791, Length=351, Percent_Identity=24.5014245014245, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4885441, Length=383, Percent_Identity=23.4986945169713, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI223718438, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI5031955, Length=279, Percent_Identity=26.8817204301075, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI148728191, Length=264, Percent_Identity=24.6212121212121, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI154800443, Length=387, Percent_Identity=24.2894056847545, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI2367379, Length=422, Percent_Identity=31.9905213270142, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789515, Length=422, Percent_Identity=30.5687203791469, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=28.6697247706422, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87082320, Length=416, Percent_Identity=29.0865384615385, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI2367193, Length=301, Percent_Identity=23.9202657807309, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082310, Length=238, Percent_Identity=25.6302521008403, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533556, Length=419, Percent_Identity=24.8210023866348, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115533554, Length=419, Percent_Identity=24.8210023866348, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17552542, Length=411, Percent_Identity=26.0340632603406, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71997452, Length=427, Percent_Identity=22.248243559719, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71991448, Length=363, Percent_Identity=25.068870523416, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71991453, Length=412, Percent_Identity=24.0291262135922, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535049, Length=389, Percent_Identity=22.6221079691517, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32565916, Length=254, Percent_Identity=24.4094488188976, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=256, Percent_Identity=24.21875, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17554148, Length=418, Percent_Identity=20.8133971291866, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=358, Percent_Identity=20.9497206703911, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=358, Percent_Identity=20.9497206703911, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=319, Percent_Identity=21.0031347962382, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554962, Length=356, Percent_Identity=20.7865168539326, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17569727, Length=260, Percent_Identity=23.4615384615385, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560966, Length=381, Percent_Identity=21.7847769028871, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=261, Percent_Identity=21.8390804597701, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25141341, Length=289, Percent_Identity=20.0692041522491, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641682, Length=395, Percent_Identity=24.3037974683544, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24648416, Length=310, Percent_Identity=24.5161290322581, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356189, Length=310, Percent_Identity=24.5161290322581, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550460, Length=459, Percent_Identity=24.1830065359477, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655255, Length=433, Percent_Identity=24.4803695150115, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24655271, Length=445, Percent_Identity=24.9438202247191, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20130135, Length=400, Percent_Identity=25, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24654215, Length=374, Percent_Identity=25.4010695187166, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19922400, Length=373, Percent_Identity=24.9329758713137, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24658658, Length=447, Percent_Identity=25.7270693512304, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24653727, Length=403, Percent_Identity=21.3399503722084, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24583789, Length=311, Percent_Identity=25.4019292604502, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573708, Length=243, Percent_Identity=26.3374485596708, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573707, Length=243, Percent_Identity=26.3374485596708, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24584153, Length=361, Percent_Identity=22.1606648199446, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20130167, Length=395, Percent_Identity=22.2784810126582, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24658666, Length=423, Percent_Identity=23.6406619385343, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24639764, Length=416, Percent_Identity=22.3557692307692, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573299, Length=316, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550495, Length=443, Percent_Identity=22.5733634311512, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281361682, Length=339, Percent_Identity=23.598820058997, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920686, Length=431, Percent_Identity=23.8979118329466, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI20129235, Length=385, Percent_Identity=23.3766233766234, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI62484226, Length=390, Percent_Identity=23.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658689, Length=451, Percent_Identity=22.6164079822616, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658674, Length=285, Percent_Identity=24.2105263157895, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45552797, Length=401, Percent_Identity=22.6932668329177, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580790, Length=274, Percent_Identity=21.5328467153285, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45550364, Length=416, Percent_Identity=24.5192307692308, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221474708, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45963; Mature: 45963

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCHHCCC
>Mature Secondary Structure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CCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]