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The map label for this gene is aspC [H]

Identifier: 170749805

GI number: 170749805

Start: 3613182

End: 3614387

Strand: Direct

Name: aspC [H]

Synonym: Mrad2831_3404

Alternate gene names: 170749805

Gene position: 3613182-3614387 (Clockwise)

Preceding gene: 170749801

Following gene: 170749806

Centisome position: 59.45

GC content: 69.32

Gene sequence:

>1206_bases
ATGACCTCGCTGTTCGCCGGCATCCAGGACGCGCCGCTCGACCCGATCATGCGCCTGTTCGAGGCCTTCAACGCCGACCC
GAGCCCGAAGAAGCTGAATCTCGTCGTCGGCGTGTACACGGACGCGGACGGCAAGGTGCCGCGCCTGCGCGCCGTGCAGA
CCGCCGAGAAGCGCTGGATCGAGAAGGGCCTGCCCAAGACCTACCGGCCGATCGAGGGCACGAAGCCGTTCCGCGACGCC
GTCCAGGAGCTGCTGTTCGGCAAGGGTGCGCCGATCCTGTCCCAGAACCGGGCCGCGACGCTCCAGAGCATCGGCGGCAC
CGGCGCCCTGAAGACCGGCGCCGACCTGCTGGCCAAACTCTACCCAGGCGCCACCGTGGCGGTGAGCAACCCGAGCTGGG
AGAACCACAAGGCCCTGTTCAGCCAGGCCGGCTTCACCGTGGTCGACTACCCCTACTTCTCGGCCGAGACCGGCGGCGCC
GATTACCCGGCCATGAAGGCAAATCTCCAGGATCTGCCGAAGGGCTCGATCGTGGTGCTGCACGCCTGCTGCCACAACCC
GACCGGCGCCGATCTCAGCCTCGACGAGTGGCGCGACCTCGTGCCCCTGATGGCCGAGCGCGGCCTGATCCCGTTCCTCG
ACATCGCCTACCAGGGCTTCGGCAACGGCCTCGACGCCGACGCCGAGCCGGTGCGCCTGTTCGCGGAGTCCGGCCAGGAG
TTCCTCGTCGCCTCCTCGTTCTCGAAGTCGTTCTCGCTCTACGGCGAGCGCGTCGGCGCGCTGACCATCGTGGCCGAGAG
CCCGGCCGCGAAGGCCAAGGTCGAGGCCTTCGCCAAGCGCCTCGTCCGGGCGAGCTACTCGAACCCGCACACCCACGGTG
CGGCGATCGTCGAGATCGTGCTGACCGATCCGGAGCTGCGCGCCGACTGGGAGCGGGAGCTCGCCGAGATGCGCGACCGG
ATCCGCGCCATGCGCGAGCGGATGGCCGACAGCCTGCAGCAGCGCCACCCCGAGCGCGGCTTCGACGCCATCAAGGCGCA
GAAGGGCATGTTCTCCTACACGGGCCTGAGCCCCGCCGAAGCCACCCGCCTGCGCGAGGAGCACGAGGTCTACGCTCTGG
AGACCGGCCGGATCTGCGTGGCCGCGGTCAACACCCACAACATCGACCACGTCATCGACGCGATCGACGCGGTGGTGAAG
GGCTGA

Upstream 100 bases:

>100_bases
CGCGATGTGCGGAATAAGGGCATCGGCCCGGCCCGTCGCCGGGCGTGCCGGCACCTCTCCACGCGTGGCCGGCCGAGACC
CTCTGGGACGATTGACGATC

Downstream 100 bases:

>100_bases
TCCCGCGTGGCGGTCCGCAAGCGCGTCTGCCGATTCAACGTCTGGATCAACCCGGTCTTCGACGCGCGCCTGGGGGCCGA
GCCCGACATCGACCTGCAGG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTSLFAGIQDAPLDPIMRLFEAFNADPSPKKLNLVVGVYTDADGKVPRLRAVQTAEKRWIEKGLPKTYRPIEGTKPFRDA
VQELLFGKGAPILSQNRAATLQSIGGTGALKTGADLLAKLYPGATVAVSNPSWENHKALFSQAGFTVVDYPYFSAETGGA
DYPAMKANLQDLPKGSIVVLHACCHNPTGADLSLDEWRDLVPLMAERGLIPFLDIAYQGFGNGLDADAEPVRLFAESGQE
FLVASSFSKSFSLYGERVGALTIVAESPAAKAKVEAFAKRLVRASYSNPHTHGAAIVEIVLTDPELRADWERELAEMRDR
IRAMRERMADSLQQRHPERGFDAIKAQKGMFSYTGLSPAEATRLREEHEVYALETGRICVAAVNTHNIDHVIDAIDAVVK
G

Sequences:

>Translated_401_residues
MTSLFAGIQDAPLDPIMRLFEAFNADPSPKKLNLVVGVYTDADGKVPRLRAVQTAEKRWIEKGLPKTYRPIEGTKPFRDA
VQELLFGKGAPILSQNRAATLQSIGGTGALKTGADLLAKLYPGATVAVSNPSWENHKALFSQAGFTVVDYPYFSAETGGA
DYPAMKANLQDLPKGSIVVLHACCHNPTGADLSLDEWRDLVPLMAERGLIPFLDIAYQGFGNGLDADAEPVRLFAESGQE
FLVASSFSKSFSLYGERVGALTIVAESPAAKAKVEAFAKRLVRASYSNPHTHGAAIVEIVLTDPELRADWERELAEMRDR
IRAMRERMADSLQQRHPERGFDAIKAQKGMFSYTGLSPAEATRLREEHEVYALETGRICVAAVNTHNIDHVIDAIDAVVK
G
>Mature_400_residues
TSLFAGIQDAPLDPIMRLFEAFNADPSPKKLNLVVGVYTDADGKVPRLRAVQTAEKRWIEKGLPKTYRPIEGTKPFRDAV
QELLFGKGAPILSQNRAATLQSIGGTGALKTGADLLAKLYPGATVAVSNPSWENHKALFSQAGFTVVDYPYFSAETGGAD
YPAMKANLQDLPKGSIVVLHACCHNPTGADLSLDEWRDLVPLMAERGLIPFLDIAYQGFGNGLDADAEPVRLFAESGQEF
LVASSFSKSFSLYGERVGALTIVAESPAAKAKVEAFAKRLVRASYSNPHTHGAAIVEIVLTDPELRADWERELAEMRDRI
RAMRERMADSLQQRHPERGFDAIKAQKGMFSYTGLSPAEATRLREEHEVYALETGRICVAAVNTHNIDHVIDAIDAVVKG

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4504067, Length=407, Percent_Identity=41.031941031941, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI73486658, Length=395, Percent_Identity=38.4810126582278, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI117414139, Length=396, Percent_Identity=26.5151515151515, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1790488, Length=387, Percent_Identity=48.578811369509, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=45.4545454545455, Blast_Score=361, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71981858, Length=397, Percent_Identity=38.7909319899244, Blast_Score=309, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=38.8471177944862, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17569539, Length=401, Percent_Identity=37.9052369077307, Blast_Score=287, Evalue=9e-78,
Organism=Caenorhabditis elegans, GI17569537, Length=404, Percent_Identity=31.1881188118812, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17550384, Length=271, Percent_Identity=33.9483394833948, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=37.5586854460094, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=36.1179361179361, Blast_Score=262, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6322743, Length=439, Percent_Identity=31.4350797266515, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24580972, Length=402, Percent_Identity=40.0497512437811, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24580970, Length=401, Percent_Identity=40.1496259351621, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=40.5612244897959, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24654046, Length=403, Percent_Identity=39.7022332506204, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI19922362, Length=403, Percent_Identity=39.7022332506204, Blast_Score=295, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43725; Mature: 43594

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLFAGIQDAPLDPIMRLFEAFNADPSPKKLNLVVGVYTDADGKVPRLRAVQTAEKRWI
CCCHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
EKGLPKTYRPIEGTKPFRDAVQELLFGKGAPILSQNRAATLQSIGGTGALKTGADLLAKL
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHH
YPGATVAVSNPSWENHKALFSQAGFTVVDYPYFSAETGGADYPAMKANLQDLPKGSIVVL
CCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHCCHHHCCCCCEEEE
HACCHNPTGADLSLDEWRDLVPLMAERGLIPFLDIAYQGFGNGLDADAEPVRLFAESGQE
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCE
FLVASSFSKSFSLYGERVGALTIVAESPAAKAKVEAFAKRLVRASYSNPHTHGAAIVEIV
EEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
LTDPELRADWERELAEMRDRIRAMRERMADSLQQRHPERGFDAIKAQKGMFSYTGLSPAE
ECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCCHHH
ATRLREEHEVYALETGRICVAAVNTHNIDHVIDAIDAVVKG
HHHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLFAGIQDAPLDPIMRLFEAFNADPSPKKLNLVVGVYTDADGKVPRLRAVQTAEKRWI
CCHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
EKGLPKTYRPIEGTKPFRDAVQELLFGKGAPILSQNRAATLQSIGGTGALKTGADLLAKL
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHH
YPGATVAVSNPSWENHKALFSQAGFTVVDYPYFSAETGGADYPAMKANLQDLPKGSIVVL
CCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHCCHHHCCCCCEEEE
HACCHNPTGADLSLDEWRDLVPLMAERGLIPFLDIAYQGFGNGLDADAEPVRLFAESGQE
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCE
FLVASSFSKSFSLYGERVGALTIVAESPAAKAKVEAFAKRLVRASYSNPHTHGAAIVEIV
EEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
LTDPELRADWERELAEMRDRIRAMRERMADSLQQRHPERGFDAIKAQKGMFSYTGLSPAE
ECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCCHHH
ATRLREEHEVYALETGRICVAAVNTHNIDHVIDAIDAVVKG
HHHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]