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The map label for this gene is solA [H]

Identifier: 170749712

GI number: 170749712

Start: 3512139

End: 3513311

Strand: Reverse

Name: solA [H]

Synonym: Mrad2831_3311

Alternate gene names: 170749712

Gene position: 3513311-3512139 (Counterclockwise)

Preceding gene: 170749714

Following gene: 170749711

Centisome position: 57.81

GC content: 72.72

Gene sequence:

>1173_bases
GTGCCGGCCGTGAGTCGCCGCTACGATGTCGCTGTCCTGGGCCTCGGCGCGATGGGCAGCGCCGCGCTCTACCAGCTGGC
GAAACGGGGCGCCTCGGTGATCGGGCTCGACCGCTTCGCGCCGCCCCACGCCCTCGGGTCCAGCCACGGCGAGACGCGGA
TCACCCGCCAGGCGGTCGGCGAGGGCGCCGACTACGTCCCCTTCGTCACCGCCTCGCACCGCATCTGGCGCGAGCTGGAG
GCCGAAACCGGCGAGACTTTGCTGAACGCCTGCGGGGCGCTCGTCATGGCCCCGGGCCACGGCGTCTCCTCGCATCACGG
CAAGCCGGACTTCGTCGGACGCTCCATCAGCGCCGCTGAGGGCGCCGGCATCGTCCACGAGGTGCTCGACGGCGCGGAGG
TGGCCCGCCGGTTCCCGCAATTCCTCAACCTCGCGGGCGACGAGAAGGCCTATTACGAGCCGGGCGGCGGCTACGTGTTC
CCGGAGCGCTGCCTCGCGGCGCAGCTCGGCCGCGCGGGTGCCGCGGGTGCCGAGATCCGCACGAACTGCGCGGTGGTCGG
GCTTCAGCAGGACGGGAGCGGCGTCCGCGTCGACACGGCGGAGGGGACCATCCTGGCCGACCGCGCCGTCGTGGCCGCGG
GCGCCTGGACGGCCCCGCTGCTCGGGAGCCCGTTCGACCGACTGCTGACCGTCCGCCGGCAGCTCCTGCACTGGTACGCG
CTCGCGGACGAGACCGCCTACGGGCCGCACGCGCCGGTCTTCATCTGGATGTACGGGACGAGCGACACGGAATACCTCTA
CGGCTTCCCGCCGCTGGACGGGTCCATCAAGGTCGCGACGGAGCAGTACAGCACCACCACCACCGCCGACGGGGTGGCGC
GTCGCGTCGATCCGTCGGAATCCGACGAGATGTACCGGCTGCGCGTCGCGAACCGGCTGGCCGGCGCGACTCCGGAGCTC
GTCCAGGCCGCGGCCTGCGTCTACACGGTCACCCCCGACCGCGGCTTCATCATCGACCGGCATCCCGAGATGGAGCGCGT
GCGGGTGGTGTCCGCCTGCTCGGGGCACGGGTTCAAGCACTCGGCCGGCATCGGCGAGGCCGTCGCGGCTGAGCTGGCCG
GGACCGGCAGCACCGTCGATCTCGCGCCCTTCGCCCTGGCACGTTTCAGTTGA

Upstream 100 bases:

>100_bases
CGTCTTCCTGTGCCGCGCGAGACCGCCCCCGGATGCCTCGACCTGCCGATCTTCCTCCGTTCCGCGCTGCGGCGGTGTCC
CGTCCCGGCAGCGAGCGGGC

Downstream 100 bases:

>100_bases
TGCGCCGGCTAATGGCTCGTGGATTGCTTGAAACCGTGCCAAGATCAGTCGACCCGAGCAGGAAAGACCCGATGCGTCTC
ACGATCCGCACCCTTCTGAC

Product: N-methyltryptophan oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPAVSRRYDVAVLGLGAMGSAALYQLAKRGASVIGLDRFAPPHALGSSHGETRITRQAVGEGADYVPFVTASHRIWRELE
AETGETLLNACGALVMAPGHGVSSHHGKPDFVGRSISAAEGAGIVHEVLDGAEVARRFPQFLNLAGDEKAYYEPGGGYVF
PERCLAAQLGRAGAAGAEIRTNCAVVGLQQDGSGVRVDTAEGTILADRAVVAAGAWTAPLLGSPFDRLLTVRRQLLHWYA
LADETAYGPHAPVFIWMYGTSDTEYLYGFPPLDGSIKVATEQYSTTTTADGVARRVDPSESDEMYRLRVANRLAGATPEL
VQAAACVYTVTPDRGFIIDRHPEMERVRVVSACSGHGFKHSAGIGEAVAAELAGTGSTVDLAPFALARFS

Sequences:

>Translated_390_residues
MPAVSRRYDVAVLGLGAMGSAALYQLAKRGASVIGLDRFAPPHALGSSHGETRITRQAVGEGADYVPFVTASHRIWRELE
AETGETLLNACGALVMAPGHGVSSHHGKPDFVGRSISAAEGAGIVHEVLDGAEVARRFPQFLNLAGDEKAYYEPGGGYVF
PERCLAAQLGRAGAAGAEIRTNCAVVGLQQDGSGVRVDTAEGTILADRAVVAAGAWTAPLLGSPFDRLLTVRRQLLHWYA
LADETAYGPHAPVFIWMYGTSDTEYLYGFPPLDGSIKVATEQYSTTTTADGVARRVDPSESDEMYRLRVANRLAGATPEL
VQAAACVYTVTPDRGFIIDRHPEMERVRVVSACSGHGFKHSAGIGEAVAAELAGTGSTVDLAPFALARFS
>Mature_389_residues
PAVSRRYDVAVLGLGAMGSAALYQLAKRGASVIGLDRFAPPHALGSSHGETRITRQAVGEGADYVPFVTASHRIWRELEA
ETGETLLNACGALVMAPGHGVSSHHGKPDFVGRSISAAEGAGIVHEVLDGAEVARRFPQFLNLAGDEKAYYEPGGGYVFP
ERCLAAQLGRAGAAGAEIRTNCAVVGLQQDGSGVRVDTAEGTILADRAVVAAGAWTAPLLGSPFDRLLTVRRQLLHWYAL
ADETAYGPHAPVFIWMYGTSDTEYLYGFPPLDGSIKVATEQYSTTTTADGVARRVDPSESDEMYRLRVANRLAGATPELV
QAAACVYTVTPDRGFIIDRHPEMERVRVVSACSGHGFKHSAGIGEAVAAELAGTGSTVDLAPFALARFS

Specific function: Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L- alanine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=401, Percent_Identity=29.6758104738155, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1787298, Length=392, Percent_Identity=29.5918367346939, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI115535191, Length=401, Percent_Identity=27.930174563591, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25147318, Length=405, Percent_Identity=28.1481481481481, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41212; Mature: 41081

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVSRRYDVAVLGLGAMGSAALYQLAKRGASVIGLDRFAPPHALGSSHGETRITRQAVG
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHC
EGADYVPFVTASHRIWRELEAETGETLLNACGALVMAPGHGVSSHHGKPDFVGRSISAAE
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
GAGIVHEVLDGAEVARRFPQFLNLAGDEKAYYEPGGGYVFPERCLAAQLGRAGAAGAEIR
CCHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCCEECHHHHHHHHHCCCCCCCCEEE
TNCAVVGLQQDGSGVRVDTAEGTILADRAVVAAGAWTAPLLGSPFDRLLTVRRQLLHWYA
CCEEEEEEEECCCCEEEECCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
LADETAYGPHAPVFIWMYGTSDTEYLYGFPPLDGSIKVATEQYSTTTTADGVARRVDPSE
HHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCC
SDEMYRLRVANRLAGATPELVQAAACVYTVTPDRGFIIDRHPEMERVRVVSACSGHGFKH
CCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCC
SAGIGEAVAAELAGTGSTVDLAPFALARFS
CCCCCHHHHHHHCCCCCCEEHHHHHHHHCC
>Mature Secondary Structure 
PAVSRRYDVAVLGLGAMGSAALYQLAKRGASVIGLDRFAPPHALGSSHGETRITRQAVG
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHC
EGADYVPFVTASHRIWRELEAETGETLLNACGALVMAPGHGVSSHHGKPDFVGRSISAAE
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
GAGIVHEVLDGAEVARRFPQFLNLAGDEKAYYEPGGGYVFPERCLAAQLGRAGAAGAEIR
CCHHHHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCCEECHHHHHHHHHCCCCCCCCEEE
TNCAVVGLQQDGSGVRVDTAEGTILADRAVVAAGAWTAPLLGSPFDRLLTVRRQLLHWYA
CCEEEEEEEECCCCEEEECCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
LADETAYGPHAPVFIWMYGTSDTEYLYGFPPLDGSIKVATEQYSTTTTADGVARRVDPSE
HHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCC
SDEMYRLRVANRLAGATPELVQAAACVYTVTPDRGFIIDRHPEMERVRVVSACSGHGFKH
CCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCC
SAGIGEAVAAELAGTGSTVDLAPFALARFS
CCCCCHHHHHHHCCCCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10220347; 10913293; 11087383; 10368302 [H]