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The map label for this gene is ydcR [C]

Identifier: 170749692

GI number: 170749692

Start: 3490275

End: 3491666

Strand: Reverse

Name: ydcR [C]

Synonym: Mrad2831_3290

Alternate gene names: 170749692

Gene position: 3491666-3490275 (Counterclockwise)

Preceding gene: 170749695

Following gene: 170749691

Centisome position: 57.45

GC content: 73.2

Gene sequence:

>1392_bases
ATGTTGGAATCCTGGAGCCCGACAATCGCCGGCGAGACCGGGCCCAAGTACCTCGCCATCGTCCGGGCGCTGACCGCGGA
CATCCGTGCCGGCCGGCTCGCGCCGGGAGCGCGCCTGCCGCCGCAGCGCGCGCTGGCGAAGCAGCTGAACGTCGATCTCA
CGACGGTGACGCGCGCCTTCAACGAGGCGCGCCGAGTGGGATTGATCGACGCGACGGCTGGCCGGGGCAGTTTCGTCCGG
GGGCCCCGGTCGCCGGCCGCGGAGGTGCCCCGGCCTGATCCGTCCGGCAGCATCGACTTCAGCATGAACATGCCGCCCCA
GCCCGCGGCGGCGCGACTGGCGGAGCGCCTGGAGGCAGGTCTGTCGCGGCTCGCCGGATCGTCCGGCTTCCTCGCCCGAA
TGCAGTACCAGGACAGTGCCGGGAACCTGGCCGACCGGGCGGCGGCGGCCCACTGGCTCGGTCAACGGCTCGGGACACTC
CCGGTGCAGCGCGTCCTCGTGGCGGGCGGTGCCCAGGTCGTGCTCGCCGCCGTGCTCGCCGCCATCCTGAAGCCGGGCGA
CGCCCTCTGCGTCCCGGCGCTCACCTATCCCGGGCTGCGCACGGCCGCGGAGCGCCGCGGAGTCCGCCTCGTGCCGGTGG
CCGGCGACGCGGAAGGGCTCGAGCCGGACGCCTTCCGCGAACGCTGCGAAACCGAGCGTCCGCGGGCTCTGTACCTCGTT
CCGACGCTCGACAACCCAACCACCGCGACCCTGCCGGCGGTCCGGCGGCGGCAGATTGCCGAGATTGCCAGAACGCACGG
CGTCGCCATCATCGAGGACGACGCGTACGGCGCACTGCCCCTGGACGCTCCGGCTCCCATCGCGTCCCAGGCGAGCGACA
TCACGTGGCACATCGCGACGCTGTCCAAATGCGCGAGTCCCGGCCTGCGCGTCGCCTACGTCGCGGTCCCGGGAACGAAC
GAGGCGGTGCGGCTGGCGGCCGAACTGCGCGCCATCAACTTGATGGCCTCGCCTCTCACGGCCGCGCTCGCCTCACACTG
GATCGCCGAGGGCGAGCTCGACGCCGTCGTCGCGGCGATCCGGCAGGAGAACGCGCTCAGGCAGGCCGTCGCGCGCGAGA
CGCTCCAGGGTCTCGACGTCCGGGGGCATCCGTGCGGGCACCATCTGTGGCTCCGGCTTCCCGCTTTCTGGCGTCGCGGC
GAGTTCGGCGCCCACGCGCGGCAGCTCGGCGTGTCGGTCATCCCGAGCGACGCCTTCGCGGTCGGGCCTGCTCCGGAAGC
CATCCGCGTCTCCCTGGGCGCGGCGCCGGACGCCGAGACGCTCCGATACGGCCTCAGCCTGCTCGCGACGTTGCTGGCGC
ATCCGCCCGGCGCGATCTCGACCGTTGTCTGA

Upstream 100 bases:

>100_bases
CGACCCGGCGAATCGTCCGCCGAGCGCGGAACGGACGCACGGCTGTGCTCGCCGGTCGTACTCTGAATGTATGCATACGC
TAGCGCGAGAACAGGGGTCA

Downstream 100 bases:

>100_bases
GCCGGCCGAGGCGGCCCGTGCCTCGCGCGTTCGGGCAGTCCGCGCCGCCCGGACGAGCGCTGTCCCTCGATCGTCGGCCG
ACTCCTGCTGGGGGAGGCGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLESWSPTIAGETGPKYLAIVRALTADIRAGRLAPGARLPPQRALAKQLNVDLTTVTRAFNEARRVGLIDATAGRGSFVR
GPRSPAAEVPRPDPSGSIDFSMNMPPQPAAARLAERLEAGLSRLAGSSGFLARMQYQDSAGNLADRAAAAHWLGQRLGTL
PVQRVLVAGGAQVVLAAVLAAILKPGDALCVPALTYPGLRTAAERRGVRLVPVAGDAEGLEPDAFRERCETERPRALYLV
PTLDNPTTATLPAVRRRQIAEIARTHGVAIIEDDAYGALPLDAPAPIASQASDITWHIATLSKCASPGLRVAYVAVPGTN
EAVRLAAELRAINLMASPLTAALASHWIAEGELDAVVAAIRQENALRQAVARETLQGLDVRGHPCGHHLWLRLPAFWRRG
EFGAHARQLGVSVIPSDAFAVGPAPEAIRVSLGAAPDAETLRYGLSLLATLLAHPPGAISTVV

Sequences:

>Translated_463_residues
MLESWSPTIAGETGPKYLAIVRALTADIRAGRLAPGARLPPQRALAKQLNVDLTTVTRAFNEARRVGLIDATAGRGSFVR
GPRSPAAEVPRPDPSGSIDFSMNMPPQPAAARLAERLEAGLSRLAGSSGFLARMQYQDSAGNLADRAAAAHWLGQRLGTL
PVQRVLVAGGAQVVLAAVLAAILKPGDALCVPALTYPGLRTAAERRGVRLVPVAGDAEGLEPDAFRERCETERPRALYLV
PTLDNPTTATLPAVRRRQIAEIARTHGVAIIEDDAYGALPLDAPAPIASQASDITWHIATLSKCASPGLRVAYVAVPGTN
EAVRLAAELRAINLMASPLTAALASHWIAEGELDAVVAAIRQENALRQAVARETLQGLDVRGHPCGHHLWLRLPAFWRRG
EFGAHARQLGVSVIPSDAFAVGPAPEAIRVSLGAAPDAETLRYGLSLLATLLAHPPGAISTVV
>Mature_463_residues
MLESWSPTIAGETGPKYLAIVRALTADIRAGRLAPGARLPPQRALAKQLNVDLTTVTRAFNEARRVGLIDATAGRGSFVR
GPRSPAAEVPRPDPSGSIDFSMNMPPQPAAARLAERLEAGLSRLAGSSGFLARMQYQDSAGNLADRAAAAHWLGQRLGTL
PVQRVLVAGGAQVVLAAVLAAILKPGDALCVPALTYPGLRTAAERRGVRLVPVAGDAEGLEPDAFRERCETERPRALYLV
PTLDNPTTATLPAVRRRQIAEIARTHGVAIIEDDAYGALPLDAPAPIASQASDITWHIATLSKCASPGLRVAYVAVPGTN
EAVRLAAELRAINLMASPLTAALASHWIAEGELDAVVAAIRQENALRQAVARETLQGLDVRGHPCGHHLWLRLPAFWRRG
EFGAHARQLGVSVIPSDAFAVGPAPEAIRVSLGAAPDAETLRYGLSLLATLLAHPPGAISTVV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=313, Percent_Identity=26.517571884984, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI33469970, Length=313, Percent_Identity=26.517571884984, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI1787710, Length=440, Percent_Identity=24.5454545454545, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790797, Length=480, Percent_Identity=24.7916666666667, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 48740; Mature: 48740

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00024 HEMOPEXIN ; PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESWSPTIAGETGPKYLAIVRALTADIRAGRLAPGARLPPQRALAKQLNVDLTTVTRAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
NEARRVGLIDATAGRGSFVRGPRSPAAEVPRPDPSGSIDFSMNMPPQPAAARLAERLEAG
HHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
LSRLAGSSGFLARMQYQDSAGNLADRAAAAHWLGQRLGTLPVQRVLVAGGAQVVLAAVLA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHH
AILKPGDALCVPALTYPGLRTAAERRGVRLVPVAGDAEGLEPDAFRERCETERPRALYLV
HHHCCCCCEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEE
PTLDNPTTATLPAVRRRQIAEIARTHGVAIIEDDAYGALPLDAPAPIASQASDITWHIAT
ECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHH
LSKCASPGLRVAYVAVPGTNEAVRLAAELRAINLMASPLTAALASHWIAEGELDAVVAAI
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RQENALRQAVARETLQGLDVRGHPCGHHLWLRLPAFWRRGEFGAHARQLGVSVIPSDAFA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECHHHHHCCCCCHHHHHCCCEECCCCCEE
VGPAPEAIRVSLGAAPDAETLRYGLSLLATLLAHPPGAISTVV
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLESWSPTIAGETGPKYLAIVRALTADIRAGRLAPGARLPPQRALAKQLNVDLTTVTRAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
NEARRVGLIDATAGRGSFVRGPRSPAAEVPRPDPSGSIDFSMNMPPQPAAARLAERLEAG
HHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
LSRLAGSSGFLARMQYQDSAGNLADRAAAAHWLGQRLGTLPVQRVLVAGGAQVVLAAVLA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHH
AILKPGDALCVPALTYPGLRTAAERRGVRLVPVAGDAEGLEPDAFRERCETERPRALYLV
HHHCCCCCEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEE
PTLDNPTTATLPAVRRRQIAEIARTHGVAIIEDDAYGALPLDAPAPIASQASDITWHIAT
ECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHH
LSKCASPGLRVAYVAVPGTNEAVRLAAELRAINLMASPLTAALASHWIAEGELDAVVAAI
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RQENALRQAVARETLQGLDVRGHPCGHHLWLRLPAFWRRGEFGAHARQLGVSVIPSDAFA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECHHHHHCCCCCHHHHHCCCEECCCCCEE
VGPAPEAIRVSLGAAPDAETLRYGLSLLATLLAHPPGAISTVV
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400197 [H]