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The map label for this gene is 170749619

Identifier: 170749619

GI number: 170749619

Start: 3401546

End: 3402982

Strand: Reverse

Name: 170749619

Synonym: Mrad2831_3216

Alternate gene names: NA

Gene position: 3402982-3401546 (Counterclockwise)

Preceding gene: 170749620

Following gene: 170749618

Centisome position: 55.99

GC content: 74.18

Gene sequence:

>1437_bases
ATGGACCAGATCCGCACGACCCGGACCGATCTCGGCGAGATGGACGCGGTGGAGCTCGGGGCGCTGTTCGCGTCCGGCCG
GGTCTCGCCGGTGGAGGCCGCGCAGGCGGCGCTGGCACGCATCGAGCGGTTCAACCCGCAGGTGAATGCCTTCGCGTATG
TCGCGCCCGAACCGGCGCTCGAGGCCGCGCGGGCCTCGGAGGCGCGCTGGGCGAAGGGCGAGGCGCTGAGCCCGATCGAC
GGGGTGCCGACGACGATCAAGGAACTGACCGCCGTCAAGGGCATCCCGTGGCGGCGGGGCTCGAAGCTCACCGGCGAGGC
CCCGGCCACCGACGAGATCCTGGTGATGCGGCGCCTGCGCGCCGCCGGGGCGGTCATCCTCGGCACGACCACGTCGCCGG
AATTCGGCTGGAAGGGCGTGACCCACGGCCCGGCCTTCGGCAACACCGTCAATCCCTGGGGCACCGATCGGGCCTCGGGG
GGCTCCTCGGGCGGGGCCGGCGTCGCCGCCGCCCTGAACATGGGCGTGCTGCACGAGGGATCCGACGGGGCGGGCTCGAT
CCGCATCCCGTCGTCGTTCTGCGGCGTCTTCGGGATCAAGCCGACCTTCGGCTGGCTGGCCACCGACGCGCCGACGCCGC
TGCGGGACATGGCCCATCGCGGCCCGCTCACCCGGACGGTGGCGGATTCCGCCCTGTTCCTGAACGCCGTCACGGGCCCG
TCCCCGGACGGCCTGTACGGCGACTGCCCGAGCCCCGTCCCGGACTGGACGGAGGCCGCCCGCGGCGGCGTCGCGGGCCT
GCGCATCGGCTACAGCCGGACCTTCGGCTACGCCCGCGTCGATCCCGAGGTCGCCGCCGCGGTGGACCGGGCCGCCGCCC
GCCTCGCCGCGATGGGCGCCGTCGTCGAGGAGGCCGATCCCGGCTTCGCCTCGCCCCTGGAGGCGCTGCGGGTGATCTGG
TTCTCCGCCATGGCGGTCCTCGTGGATCGCTTCGCCCCCACCGAGACGGATCGCGCGCGCATGGATCCCGGATTCGTCGC
CGTCGCCGAGATCGGGCGCCGCACCAGCGCGGCGGACCTCCTGGCGGCGGAGCAGGTCCGGGCCGAGCTGAAGGTCACGA
TGGCGCGCTTCCACGCGCGCTACGACCTGCTCCTCTCCCCGACCATGCCGGTCACCGCGATCCCGGCGGGCATCGACTTC
CCCGAGGGGCAGGGCATGACCGACTGGACCGACTGGAGCCCCTTCACCTACCCGTTCAACATGACCGGCCAGGCCGCACT
CTCGGTGCCCTGCGGCTTCGATTCGGGCGGCCTGCCGATCGGGCTGCAGATGGTCGCCGCCCGGTTCCGGGACGACCTCG
TCCTGCGGGCCGCCGCGGCCTACCAAGCCGCCTACCCGGAGGCGTTCCCGGACGCCCCTGTGGTCCGGCCCGCCTGA

Upstream 100 bases:

>100_bases
CCCTGTGCTTCTGCCCGCCGCTGATCATCACCGCGGAGCAGATCGGCGCGATGTTCGACGCCGTCGGCCGTGCCCTCGAC
ACGATCGCCGCGTGAGCCCG

Downstream 100 bases:

>100_bases
GGGCGCAGGGCGCGCCGGTCTCGAAGCACCTGTCTGGATCCCCGATGTCCCATCCCACGATCGACGCCCCCGAGAGCGGC
ATCGGCGCCGGCCTGTCGGT

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MDQIRTTRTDLGEMDAVELGALFASGRVSPVEAAQAALARIERFNPQVNAFAYVAPEPALEAARASEARWAKGEALSPID
GVPTTIKELTAVKGIPWRRGSKLTGEAPATDEILVMRRLRAAGAVILGTTTSPEFGWKGVTHGPAFGNTVNPWGTDRASG
GSSGGAGVAAALNMGVLHEGSDGAGSIRIPSSFCGVFGIKPTFGWLATDAPTPLRDMAHRGPLTRTVADSALFLNAVTGP
SPDGLYGDCPSPVPDWTEAARGGVAGLRIGYSRTFGYARVDPEVAAAVDRAAARLAAMGAVVEEADPGFASPLEALRVIW
FSAMAVLVDRFAPTETDRARMDPGFVAVAEIGRRTSAADLLAAEQVRAELKVTMARFHARYDLLLSPTMPVTAIPAGIDF
PEGQGMTDWTDWSPFTYPFNMTGQAALSVPCGFDSGGLPIGLQMVAARFRDDLVLRAAAAYQAAYPEAFPDAPVVRPA

Sequences:

>Translated_478_residues
MDQIRTTRTDLGEMDAVELGALFASGRVSPVEAAQAALARIERFNPQVNAFAYVAPEPALEAARASEARWAKGEALSPID
GVPTTIKELTAVKGIPWRRGSKLTGEAPATDEILVMRRLRAAGAVILGTTTSPEFGWKGVTHGPAFGNTVNPWGTDRASG
GSSGGAGVAAALNMGVLHEGSDGAGSIRIPSSFCGVFGIKPTFGWLATDAPTPLRDMAHRGPLTRTVADSALFLNAVTGP
SPDGLYGDCPSPVPDWTEAARGGVAGLRIGYSRTFGYARVDPEVAAAVDRAAARLAAMGAVVEEADPGFASPLEALRVIW
FSAMAVLVDRFAPTETDRARMDPGFVAVAEIGRRTSAADLLAAEQVRAELKVTMARFHARYDLLLSPTMPVTAIPAGIDF
PEGQGMTDWTDWSPFTYPFNMTGQAALSVPCGFDSGGLPIGLQMVAARFRDDLVLRAAAAYQAAYPEAFPDAPVVRPA
>Mature_478_residues
MDQIRTTRTDLGEMDAVELGALFASGRVSPVEAAQAALARIERFNPQVNAFAYVAPEPALEAARASEARWAKGEALSPID
GVPTTIKELTAVKGIPWRRGSKLTGEAPATDEILVMRRLRAAGAVILGTTTSPEFGWKGVTHGPAFGNTVNPWGTDRASG
GSSGGAGVAAALNMGVLHEGSDGAGSIRIPSSFCGVFGIKPTFGWLATDAPTPLRDMAHRGPLTRTVADSALFLNAVTGP
SPDGLYGDCPSPVPDWTEAARGGVAGLRIGYSRTFGYARVDPEVAAAVDRAAARLAAMGAVVEEADPGFASPLEALRVIW
FSAMAVLVDRFAPTETDRARMDPGFVAVAEIGRRTSAADLLAAEQVRAELKVTMARFHARYDLLLSPTMPVTAIPAGIDF
PEGQGMTDWTDWSPFTYPFNMTGQAALSVPCGFDSGGLPIGLQMVAARFRDDLVLRAAAAYQAAYPEAFPDAPVVRPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=506, Percent_Identity=27.6679841897233, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI195972892, Length=502, Percent_Identity=24.5019920318725, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI166795287, Length=230, Percent_Identity=33.4782608695652, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538252, Length=331, Percent_Identity=27.7945619335347, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17537465, Length=502, Percent_Identity=24.3027888446215, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17556264, Length=310, Percent_Identity=27.0967741935484, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556276, Length=309, Percent_Identity=28.4789644012945, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17556278, Length=309, Percent_Identity=28.4789644012945, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71990152, Length=293, Percent_Identity=28.6689419795222, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17543272, Length=432, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=305, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=410, Percent_Identity=24.6341463414634, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320448, Length=220, Percent_Identity=32.2727272727273, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644968, Length=510, Percent_Identity=28.0392156862745, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24648113, Length=478, Percent_Identity=28.6610878661088, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24648435, Length=499, Percent_Identity=24.4488977955912, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24648437, Length=499, Percent_Identity=24.4488977955912, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45550774, Length=499, Percent_Identity=24.4488977955912, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161078093, Length=506, Percent_Identity=26.8774703557312, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356731, Length=502, Percent_Identity=24.5019920318725, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24648441, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648439, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24652985, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922090, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652981, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652983, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 50170; Mature: 50170

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIRTTRTDLGEMDAVELGALFASGRVSPVEAAQAALARIERFNPQVNAFAYVAPEPAL
CCCCCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHH
EAARASEARWAKGEALSPIDGVPTTIKELTAVKGIPWRRGSKLTGEAPATDEILVMRRLR
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAGAVILGTTTSPEFGWKGVTHGPAFGNTVNPWGTDRASGGSSGGAGVAAALNMGVLHEG
HCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCEEECC
SDGAGSIRIPSSFCGVFGIKPTFGWLATDAPTPLRDMAHRGPLTRTVADSALFLNAVTGP
CCCCCEEECCHHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHEEEECCCC
SPDGLYGDCPSPVPDWTEAARGGVAGLRIGYSRTFGYARVDPEVAAAVDRAAARLAAMGA
CCCCCCCCCCCCCCCHHHHHCCCCCEEEECHHHCCCCEECCHHHHHHHHHHHHHHHHHHH
VVEEADPGFASPLEALRVIWFSAMAVLVDRFAPTETDRARMDPGFVAVAEIGRRTSAADL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEHHHHCCCCHHHHH
LAAEQVRAELKVTMARFHARYDLLLSPTMPVTAIPAGIDFPEGQGMTDWTDWSPFTYPFN
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECC
MTGQAALSVPCGFDSGGLPIGLQMVAARFRDDLVLRAAAAYQAAYPEAFPDAPVVRPA
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQIRTTRTDLGEMDAVELGALFASGRVSPVEAAQAALARIERFNPQVNAFAYVAPEPAL
CCCCCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHH
EAARASEARWAKGEALSPIDGVPTTIKELTAVKGIPWRRGSKLTGEAPATDEILVMRRLR
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AAGAVILGTTTSPEFGWKGVTHGPAFGNTVNPWGTDRASGGSSGGAGVAAALNMGVLHEG
HCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCEEECC
SDGAGSIRIPSSFCGVFGIKPTFGWLATDAPTPLRDMAHRGPLTRTVADSALFLNAVTGP
CCCCCEEECCHHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHEEEECCCC
SPDGLYGDCPSPVPDWTEAARGGVAGLRIGYSRTFGYARVDPEVAAAVDRAAARLAAMGA
CCCCCCCCCCCCCCCHHHHHCCCCCEEEECHHHCCCCEECCHHHHHHHHHHHHHHHHHHH
VVEEADPGFASPLEALRVIWFSAMAVLVDRFAPTETDRARMDPGFVAVAEIGRRTSAADL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEHHHHCCCCHHHHH
LAAEQVRAELKVTMARFHARYDLLLSPTMPVTAIPAGIDFPEGQGMTDWTDWSPFTYPFN
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECC
MTGQAALSVPCGFDSGGLPIGLQMVAARFRDDLVLRAAAAYQAAYPEAFPDAPVVRPA
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]