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The map label for this gene is ppiD [H]

Identifier: 170749508

GI number: 170749508

Start: 3281145

End: 3283046

Strand: Reverse

Name: ppiD [H]

Synonym: Mrad2831_3103

Alternate gene names: 170749508

Gene position: 3283046-3281145 (Counterclockwise)

Preceding gene: 170749510

Following gene: 170749507

Centisome position: 54.02

GC content: 69.19

Gene sequence:

>1902_bases
ATGCTTCAGGGCATCCGCAACGCCAGCCAGCACTGGCTCGGCAAGATCGTCTTGACGATCATCTTCACGCTGCTGATCGC
CGGTGTCGGCATCTTCGGGGTCGAGGAGTTCTTCCGCGGCGGCGCGAGCAACAAGGTGGCCACGGTCGGCAGCACGCCGA
TCACCGCCGAGCAGGTGCGCCAAGCCTACCAGAACCAGCTCCAGCGCTATCAGACGCAGCTGAAGCGTCCGCTCACGCCC
GATCAGGCGCGGATGCTCGGTCTGGACCGGCAGGTGATGTCGCAGCTGATCACCGAGGCCGCCCTCGATCAGAAGACCCA
CGATCTCGGCCTCGCCGTGCCGGATGCCTCGGTGATCAAGGCGATCCACGAGGAGAAGAGCTTCCAGAACCAGCAGGGTC
AGTTCGAGCCGCAGCTCTTCTACCAGACCCTGCAGCGCGCCGGCCTCAACGAGGGCCTGTTCGTGCGCGAGCAGCGCTCG
GTGATCGCCCGCCTTCAGCTGGCCGAGGCCGTGTCGTCGGACCTGCACGTGCCGCTCGCCATGCGCGAGGCCGTTCACCG
CTACACCACCGAGCGCCGCGCGGCCGCCTACCTGATGCTGACCCCTTCGGTGGCCGGCCAGATCCCCGATCCGACGGACG
ACGAGCTCAAGACTTGGTACGAGGCCAACAAGTCCGGCTTCCGGGCGCCGGAATTCCGGTCGGTCAACCTCCTCGTGGTC
GAGCCCGAGGCGATGGCGAAGCCCGACGCGATCACGGAGGCCGACGCCCGCGCCGCCTACGCGCTGAACAAGGACCGCTA
CGGCACGCCCGAGAAGCGCACCATCCAGCAGATCGTGTTCCCCGACGCGGCCGCCGCCGAGGCGGCCCGCAAGGCGATTA
CGGACGGCTCCAAGACCTTCGACGCGGTGGCGGCCGAGCGCGGCACCGACGAGAAGGACCTGACCCTCGGCACGCTGACC
AAGAGCGAGCTGTTCGACAAGGCCGTCGCCGACGCCGCCTTCGCGCTGCCGGAGGGCGGCGTGAGCCAGCCGGTCCAGGG
CCGGTTCGGCACGGTGCTGCTGCGCGTGACCAAGATCGAGGCCGGGACGGTGAAGCCGTTCGAGGCGGTGGAGGGAGAGA
TCCGCAAGGCCCTCGCCCTGGCCCGTGCCCGCGACGCCATGGAGACCACCCGCGACGCGATTGAGGACCAGCGCGCCGGC
GCCAAGCCCCTCGCCGACATCGCCGCGGAGCGCGGCCTCAAGATCGTCACCGTGAAGGCCGTGGACGCCAACGGCAAGGG
ACCGGACGGGCAGCGGGTCACCGACATTCCCGATGCGGAGACCACCCTGCCGGCCCTGTTCCGCGCCGAGATCGGCGGCG
ACAACGAGCCCCTGCGGACCAAGACCGGCGGCTACGTCTGGTACGACGTGACCGGGATCGACGCCGCCCACGACAAGCCC
CTCGATCAGGTCAAGGACGGCGTGAAGGCTGGCTGGACCGCGACCGAGATCGCCAAGCGCCTTCAGGCCAAGGGTCGCGA
GCTCGTCGAGAAGATCAACAAGGGCGAGACCATGGAGGCGGCCGCCCAGGAGGTCGGCGTCAACCTGCAGGAGGCGCAGG
ATCTCGCGCGCAACCAGGCCAAGGACATGCTCACGGCGGACGTCGTGAACCTGATCTTCGCGACCCCGGTCGGCAAGGCC
GGCACGGCGGCCGCGGGCGATTCGCGCGCGGTCTTCAAGGTCACGGCGGCGACGGTGCCGGCCTTCGTGGCCGATAGCCC
GAGCGACAAGCAGATCACGCAGAGCTTCCAGGCGTCGCTCGCCGATGACGTGCTGTCCCAGTACATCAGCGAGGTCCAGA
AGAACGCGGGCGTGAAGGTCGACCCGGCGGCCCTGCGGCGCGCCATCGGCGGCGAGTACTGA

Upstream 100 bases:

>100_bases
AGCCTTTGCCTGTGGACGCGAATGGTCTATCGCGGTCGGCTCTCAGGGACAGCGCCGGCCCGGTGACGGGGCGGCTGCCG
AAGGTACTCGATCACAGACC

Downstream 100 bases:

>100_bases
GGCATGGCCGAAGCGCCCGATTACGCGGCCTTCGCGGCGCGCTACGAGGCCGGGCAGCCGAGCCTCGTGGCGGTAAGCCT
CGTCGCGGACCTCGAGACGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MLQGIRNASQHWLGKIVLTIIFTLLIAGVGIFGVEEFFRGGASNKVATVGSTPITAEQVRQAYQNQLQRYQTQLKRPLTP
DQARMLGLDRQVMSQLITEAALDQKTHDLGLAVPDASVIKAIHEEKSFQNQQGQFEPQLFYQTLQRAGLNEGLFVREQRS
VIARLQLAEAVSSDLHVPLAMREAVHRYTTERRAAAYLMLTPSVAGQIPDPTDDELKTWYEANKSGFRAPEFRSVNLLVV
EPEAMAKPDAITEADARAAYALNKDRYGTPEKRTIQQIVFPDAAAAEAARKAITDGSKTFDAVAAERGTDEKDLTLGTLT
KSELFDKAVADAAFALPEGGVSQPVQGRFGTVLLRVTKIEAGTVKPFEAVEGEIRKALALARARDAMETTRDAIEDQRAG
AKPLADIAAERGLKIVTVKAVDANGKGPDGQRVTDIPDAETTLPALFRAEIGGDNEPLRTKTGGYVWYDVTGIDAAHDKP
LDQVKDGVKAGWTATEIAKRLQAKGRELVEKINKGETMEAAAQEVGVNLQEAQDLARNQAKDMLTADVVNLIFATPVGKA
GTAAAGDSRAVFKVTAATVPAFVADSPSDKQITQSFQASLADDVLSQYISEVQKNAGVKVDPAALRRAIGGEY

Sequences:

>Translated_633_residues
MLQGIRNASQHWLGKIVLTIIFTLLIAGVGIFGVEEFFRGGASNKVATVGSTPITAEQVRQAYQNQLQRYQTQLKRPLTP
DQARMLGLDRQVMSQLITEAALDQKTHDLGLAVPDASVIKAIHEEKSFQNQQGQFEPQLFYQTLQRAGLNEGLFVREQRS
VIARLQLAEAVSSDLHVPLAMREAVHRYTTERRAAAYLMLTPSVAGQIPDPTDDELKTWYEANKSGFRAPEFRSVNLLVV
EPEAMAKPDAITEADARAAYALNKDRYGTPEKRTIQQIVFPDAAAAEAARKAITDGSKTFDAVAAERGTDEKDLTLGTLT
KSELFDKAVADAAFALPEGGVSQPVQGRFGTVLLRVTKIEAGTVKPFEAVEGEIRKALALARARDAMETTRDAIEDQRAG
AKPLADIAAERGLKIVTVKAVDANGKGPDGQRVTDIPDAETTLPALFRAEIGGDNEPLRTKTGGYVWYDVTGIDAAHDKP
LDQVKDGVKAGWTATEIAKRLQAKGRELVEKINKGETMEAAAQEVGVNLQEAQDLARNQAKDMLTADVVNLIFATPVGKA
GTAAAGDSRAVFKVTAATVPAFVADSPSDKQITQSFQASLADDVLSQYISEVQKNAGVKVDPAALRRAIGGEY
>Mature_633_residues
MLQGIRNASQHWLGKIVLTIIFTLLIAGVGIFGVEEFFRGGASNKVATVGSTPITAEQVRQAYQNQLQRYQTQLKRPLTP
DQARMLGLDRQVMSQLITEAALDQKTHDLGLAVPDASVIKAIHEEKSFQNQQGQFEPQLFYQTLQRAGLNEGLFVREQRS
VIARLQLAEAVSSDLHVPLAMREAVHRYTTERRAAAYLMLTPSVAGQIPDPTDDELKTWYEANKSGFRAPEFRSVNLLVV
EPEAMAKPDAITEADARAAYALNKDRYGTPEKRTIQQIVFPDAAAAEAARKAITDGSKTFDAVAAERGTDEKDLTLGTLT
KSELFDKAVADAAFALPEGGVSQPVQGRFGTVLLRVTKIEAGTVKPFEAVEGEIRKALALARARDAMETTRDAIEDQRAG
AKPLADIAAERGLKIVTVKAVDANGKGPDGQRVTDIPDAETTLPALFRAEIGGDNEPLRTKTGGYVWYDVTGIDAAHDKP
LDQVKDGVKAGWTATEIAKRLQAKGRELVEKINKGETMEAAAQEVGVNLQEAQDLARNQAKDMLTADVVNLIFATPVGKA
GTAAAGDSRAVFKVTAATVPAFVADSPSDKQITQSFQASLADDVLSQYISEVQKNAGVKVDPAALRRAIGGEY

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=408, Percent_Identity=24.2647058823529, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68402; Mature: 68402

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQGIRNASQHWLGKIVLTIIFTLLIAGVGIFGVEEFFRGGASNKVATVGSTPITAEQVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHH
QAYQNQLQRYQTQLKRPLTPDQARMLGLDRQVMSQLITEAALDQKTHDLGLAVPDASVIK
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHCCEECCCHHHHH
AIHEEKSFQNQQGQFEPQLFYQTLQRAGLNEGLFVREQRSVIARLQLAEAVSSDLHVPLA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHH
MREAVHRYTTERRAAAYLMLTPSVAGQIPDPTDDELKTWYEANKSGFRAPEFRSVNLLVV
HHHHHHHHHHHHHHEEEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EPEAMAKPDAITEADARAAYALNKDRYGTPEKRTIQQIVFPDAAAAEAARKAITDGSKTF
CCHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
DAVAAERGTDEKDLTLGTLTKSELFDKAVADAAFALPEGGVSQPVQGRFGTVLLRVTKIE
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEC
AGTVKPFEAVEGEIRKALALARARDAMETTRDAIEDQRAGAKPLADIAAERGLKIVTVKA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEE
VDANGKGPDGQRVTDIPDAETTLPALFRAEIGGDNEPLRTKTGGYVWYDVTGIDAAHDKP
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCCCCCCC
LDQVKDGVKAGWTATEIAKRLQAKGRELVEKINKGETMEAAAQEVGVNLQEAQDLARNQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KDMLTADVVNLIFATPVGKAGTAAAGDSRAVFKVTAATVPAFVADSPSDKQITQSFQASL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
ADDVLSQYISEVQKNAGVKVDPAALRRAIGGEY
HHHHHHHHHHHHHHCCCCEECHHHHHHHHCCCC
>Mature Secondary Structure
MLQGIRNASQHWLGKIVLTIIFTLLIAGVGIFGVEEFFRGGASNKVATVGSTPITAEQVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHH
QAYQNQLQRYQTQLKRPLTPDQARMLGLDRQVMSQLITEAALDQKTHDLGLAVPDASVIK
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHCCEECCCHHHHH
AIHEEKSFQNQQGQFEPQLFYQTLQRAGLNEGLFVREQRSVIARLQLAEAVSSDLHVPLA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHH
MREAVHRYTTERRAAAYLMLTPSVAGQIPDPTDDELKTWYEANKSGFRAPEFRSVNLLVV
HHHHHHHHHHHHHHEEEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EPEAMAKPDAITEADARAAYALNKDRYGTPEKRTIQQIVFPDAAAAEAARKAITDGSKTF
CCHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
DAVAAERGTDEKDLTLGTLTKSELFDKAVADAAFALPEGGVSQPVQGRFGTVLLRVTKIE
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEC
AGTVKPFEAVEGEIRKALALARARDAMETTRDAIEDQRAGAKPLADIAAERGLKIVTVKA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEE
VDANGKGPDGQRVTDIPDAETTLPALFRAEIGGDNEPLRTKTGGYVWYDVTGIDAAHDKP
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCCCCCCC
LDQVKDGVKAGWTATEIAKRLQAKGRELVEKINKGETMEAAAQEVGVNLQEAQDLARNQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KDMLTADVVNLIFATPVGKAGTAAAGDSRAVFKVTAATVPAFVADSPSDKQITQSFQASL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
ADDVLSQYISEVQKNAGVKVDPAALRRAIGGEY
HHHHHHHHHHHHHHCCCCEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]