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The map label for this gene is yciR [C]

Identifier: 170749422

GI number: 170749422

Start: 3171388

End: 3173721

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_3015

Alternate gene names: 170749422

Gene position: 3173721-3171388 (Counterclockwise)

Preceding gene: 170749424

Following gene: 170749419

Centisome position: 52.22

GC content: 69.11

Gene sequence:

>2334_bases
ATGTTGATTTCTTTCCTGATCGATACCGATCGCAAGGCGGATCCACTCGACGCGAACCTTCGCGCGCGCGCCCGCGTCGA
GCAGCTGGACGTCGCGCTGCGCTTGGTACCCTTCACGATTCTTGTGAGTCTCAGCGTCGTACAGGTCATCGTCTACCTGT
TCTGGAACCCGGCCAATCGCGCCTATCTCGCCGGTCTCGAAACGCTCATCCTGCCGCTGGCGGTGGTCTCGCTCCAGCAG
TGCTGGCGCTGGCGCTCCCGTCCCAAGCCGCTCCAGGTGCCGTCGTCGTTCGTGCAGGGCGTCGTGCTGGCCGCGCAGGC
CTACGGGTTTCTCCTGGCCTCCATCCCGGTCATGCTCTTCTCCGGCGCCGACGCGCACGGGCGGCTGCTGATCGCCTCCA
GCATCGCGGGCCTGATCGCGACCGGCATGAGCGCGGCGGTGCTGCCGCGGGTCGCCATCGGCTATTCCGGCCTGATCATC
CTCGGCTCGTTCATCGCCCTCGCGACGACCGGGGAGGCCTTCTACATCTACGTCGCGGTCCTGCTGTTCTTCTACGCGAT
CTTCATCTGCTTCACGATCCTGCATCTGAGCCGGCTCCTGACGATGCGGGTCATCGCGCAGATCGAGCTGGAACGGCAGC
AGGAGTTCACCCACCTCCTGCTCAACGAGTTCGAGGAGAGCGCCAGCGACTGGCTCTGGGAGACCGATGCCGACCTGCGC
CTCCAGCACGTCTCGCCGCGCCTGATCGAGGTCGCCGGCTCCTCCGAGCGCCAGCTGATGGGCCTGCCGCTGGAGCGGCT
GCTGCTGCCGCCGGTGGCGCCGCCCAGGAGCCACTCGAGCACCACCCTCTGGAGCTGCATCGCCGAGCGGCGGGCCTTCC
GGAACCTGCACCTGCAGCTCGATATCGCCGGCGAGCGGCGGACTTGGTGCCTCAGCGGGAAGCCGACCTTCGACCGGGCC
GGCGCCTTCTCGGGTTACCGCGGCGTCGGCTCGGACGTGACGGAGAAGCGGCGCTCCGAGGAGCGCCTGTCCTATCTCGC
TCTGCACGATTCCCTGACGGATCTGCCCAACCGGGTCCTGTTCCACCAGCTCCAGGAAGCGGCGCGGGAACGGCTCGCGC
AGGGCGATCGGTTCGCCGTGCTGGCCCTCGACCTCGACGAGTTCAAGAGCGTCAACGACACGTTCGGCCACGCGGCCGGC
GACAAGCTCCTGAAGTCGGTCGCCGAGCGGCTCCGGAGCTTCGAGGCCTCCGATGTCCAGCTCGCCCGCCTCGCGGGCGA
CGAGTTCGCGGTCCTCGCCACCGGCCGGAGCGCCCGGGACCTGCACGCGATCGAGGCGCTCGCCAACGGCATCGTGGAGG
CGCTCGCGTCGCCGTTCACCATCGACGGCATCCGGCTGACCGTCAGCGTCAGCATCGGGATCGCGATCGCTCCGCAGGAC
GGTTGCCAGGAGATCATGCGGCGCGCCGATCTCGCGCTCTACCGCATGAAGAGCGAGGGCCGGAACGGCTACCGCTTCTA
CGAGGCCGAGATGGACGAGCGGATCGAGGCCCGCCGCGCCCTGACGGCCGATCTGCGGGGCGCCCTCGATCGGGACGAGT
TCGTCCTCTACTTCCAGCCGATCGTGGCGGCCAAGGAGTGCCGCGTGCGCGGCTTCGAGGCGCTGATCCGGTGGAAGCAC
CCGGTGCGCGGCTTCGTCTCGCCCGGCGAGTTCATCCCCCTCGCCGAGGAGACCGGGGTGATCATACCGCTGGGCGAGTG
GATCCTGCGGGAGGCATGCCGGATCGCGGCCGGCTGGCCGGGGGATGTCCGCATCGCCGTCAACCTGTCCCCGCGGCAGT
TCCGGCACTCGGACCTGACCCAGCTCGTCCGGTCCGCCCTGCGCACGAGCGGGCTGGCCGCCGCGCGCCTGGAGCTCGAG
GTGACCGAGTCGGTGTTCCTGGAGGCCACGCCGGCGATCAACGCCACGCTCTCGAAACTGCGCGAGATGGGCGTGCGGCT
GTCGCTCGACGATTTCGGAACCGGCTATTCGAGCTTGAGCTACCTGCGCCGGATCGCCTTCGACAAGATCAAGATCGACC
AGAGCTTCGTCCGGGACCTGCCGCAGGAGCGCGGCGCGGCGGCGATCGTGAGCGCGATCATCGACATGGCGACGAGTCTC
GACATGACCATCACCGCCGAGGGCGTGGAGACGGACGCGCAGCGCGCCTGCCTGCTGGAGCAGGGCTGCCACGAATTCCA
GGGCTACCTGTTCAGCAAGCCGCTGCCGGCCGAGCAGGCCGCGGCGCTGGCGCGCAGCCGTCAGCTCCTCCCGGCGGCGG
TCCGGGCGGCGTGA

Upstream 100 bases:

>100_bases
CTTGTACTTGTGCAAGCGAGCGATCGTGTATGCATCTAAACAGCCTTAGCCCCAGTTTTCGATCGTAAAGGCTTTTCAGA
AGGCGTTTGCGTCGCGCGAG

Downstream 100 bases:

>100_bases
GTCGGCCTCAGACGCCGAGGGGCGCGACCTCGGTCGGGCCGCCCCCACCCGCGACGGCGTGCGGAGACGTCTTCGGCCAG
TACGGCAGGAAGCCCTCGAT

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MLISFLIDTDRKADPLDANLRARARVEQLDVALRLVPFTILVSLSVVQVIVYLFWNPANRAYLAGLETLILPLAVVSLQQ
CWRWRSRPKPLQVPSSFVQGVVLAAQAYGFLLASIPVMLFSGADAHGRLLIASSIAGLIATGMSAAVLPRVAIGYSGLII
LGSFIALATTGEAFYIYVAVLLFFYAIFICFTILHLSRLLTMRVIAQIELERQQEFTHLLLNEFEESASDWLWETDADLR
LQHVSPRLIEVAGSSERQLMGLPLERLLLPPVAPPRSHSSTTLWSCIAERRAFRNLHLQLDIAGERRTWCLSGKPTFDRA
GAFSGYRGVGSDVTEKRRSEERLSYLALHDSLTDLPNRVLFHQLQEAARERLAQGDRFAVLALDLDEFKSVNDTFGHAAG
DKLLKSVAERLRSFEASDVQLARLAGDEFAVLATGRSARDLHAIEALANGIVEALASPFTIDGIRLTVSVSIGIAIAPQD
GCQEIMRRADLALYRMKSEGRNGYRFYEAEMDERIEARRALTADLRGALDRDEFVLYFQPIVAAKECRVRGFEALIRWKH
PVRGFVSPGEFIPLAEETGVIIPLGEWILREACRIAAGWPGDVRIAVNLSPRQFRHSDLTQLVRSALRTSGLAAARLELE
VTESVFLEATPAINATLSKLREMGVRLSLDDFGTGYSSLSYLRRIAFDKIKIDQSFVRDLPQERGAAAIVSAIIDMATSL
DMTITAEGVETDAQRACLLEQGCHEFQGYLFSKPLPAEQAAALARSRQLLPAAVRAA

Sequences:

>Translated_777_residues
MLISFLIDTDRKADPLDANLRARARVEQLDVALRLVPFTILVSLSVVQVIVYLFWNPANRAYLAGLETLILPLAVVSLQQ
CWRWRSRPKPLQVPSSFVQGVVLAAQAYGFLLASIPVMLFSGADAHGRLLIASSIAGLIATGMSAAVLPRVAIGYSGLII
LGSFIALATTGEAFYIYVAVLLFFYAIFICFTILHLSRLLTMRVIAQIELERQQEFTHLLLNEFEESASDWLWETDADLR
LQHVSPRLIEVAGSSERQLMGLPLERLLLPPVAPPRSHSSTTLWSCIAERRAFRNLHLQLDIAGERRTWCLSGKPTFDRA
GAFSGYRGVGSDVTEKRRSEERLSYLALHDSLTDLPNRVLFHQLQEAARERLAQGDRFAVLALDLDEFKSVNDTFGHAAG
DKLLKSVAERLRSFEASDVQLARLAGDEFAVLATGRSARDLHAIEALANGIVEALASPFTIDGIRLTVSVSIGIAIAPQD
GCQEIMRRADLALYRMKSEGRNGYRFYEAEMDERIEARRALTADLRGALDRDEFVLYFQPIVAAKECRVRGFEALIRWKH
PVRGFVSPGEFIPLAEETGVIIPLGEWILREACRIAAGWPGDVRIAVNLSPRQFRHSDLTQLVRSALRTSGLAAARLELE
VTESVFLEATPAINATLSKLREMGVRLSLDDFGTGYSSLSYLRRIAFDKIKIDQSFVRDLPQERGAAAIVSAIIDMATSL
DMTITAEGVETDAQRACLLEQGCHEFQGYLFSKPLPAEQAAALARSRQLLPAAVRAA
>Mature_777_residues
MLISFLIDTDRKADPLDANLRARARVEQLDVALRLVPFTILVSLSVVQVIVYLFWNPANRAYLAGLETLILPLAVVSLQQ
CWRWRSRPKPLQVPSSFVQGVVLAAQAYGFLLASIPVMLFSGADAHGRLLIASSIAGLIATGMSAAVLPRVAIGYSGLII
LGSFIALATTGEAFYIYVAVLLFFYAIFICFTILHLSRLLTMRVIAQIELERQQEFTHLLLNEFEESASDWLWETDADLR
LQHVSPRLIEVAGSSERQLMGLPLERLLLPPVAPPRSHSSTTLWSCIAERRAFRNLHLQLDIAGERRTWCLSGKPTFDRA
GAFSGYRGVGSDVTEKRRSEERLSYLALHDSLTDLPNRVLFHQLQEAARERLAQGDRFAVLALDLDEFKSVNDTFGHAAG
DKLLKSVAERLRSFEASDVQLARLAGDEFAVLATGRSARDLHAIEALANGIVEALASPFTIDGIRLTVSVSIGIAIAPQD
GCQEIMRRADLALYRMKSEGRNGYRFYEAEMDERIEARRALTADLRGALDRDEFVLYFQPIVAAKECRVRGFEALIRWKH
PVRGFVSPGEFIPLAEETGVIIPLGEWILREACRIAAGWPGDVRIAVNLSPRQFRHSDLTQLVRSALRTSGLAAARLELE
VTESVFLEATPAINATLSKLREMGVRLSLDDFGTGYSSLSYLRRIAFDKIKIDQSFVRDLPQERGAAAIVSAIIDMATSL
DMTITAEGVETDAQRACLLEQGCHEFQGYLFSKPLPAEQAAALARSRQLLPAAVRAA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=39.9538106235566, Blast_Score=315, Evalue=1e-86,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=34.4988344988345, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI226510982, Length=429, Percent_Identity=31.002331002331, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87081845, Length=235, Percent_Identity=37.4468085106383, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1786507, Length=268, Percent_Identity=31.3432835820896, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1788502, Length=239, Percent_Identity=33.8912133891213, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=36.9747899159664, Blast_Score=149, Evalue=9e-37,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=34.1666666666667, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1787055, Length=255, Percent_Identity=34.5098039215686, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI87081980, Length=246, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=31.9391634980989, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI87082096, Length=419, Percent_Identity=26.9689737470167, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788381, Length=325, Percent_Identity=30.4615384615385, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=36.9318181818182, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=32.9479768786127, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=36.4197530864198, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1787802, Length=161, Percent_Identity=34.1614906832298, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=33.974358974359, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787410, Length=154, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1789650, Length=435, Percent_Identity=20.2298850574713, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=32.9192546583851, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=33.7209302325581, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=31.547619047619, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=29.7619047619048, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 86028; Mature: 86028

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISFLIDTDRKADPLDANLRARARVEQLDVALRLVPFTILVSLSVVQVIVYLFWNPANR
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYLAGLETLILPLAVVSLQQCWRWRSRPKPLQVPSSFVQGVVLAAQAYGFLLASIPVMLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SGADAHGRLLIASSIAGLIATGMSAAVLPRVAIGYSGLIILGSFIALATTGEAFYIYVAV
CCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
LLFFYAIFICFTILHLSRLLTMRVIAQIELERQQEFTHLLLNEFEESASDWLWETDADLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LQHVSPRLIEVAGSSERQLMGLPLERLLLPPVAPPRSHSSTTLWSCIAERRAFRNLHLQL
EECCCCCEEEECCCCCCEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEE
DIAGERRTWCLSGKPTFDRAGAFSGYRGVGSDVTEKRRSEERLSYLALHDSLTDLPNRVL
EECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHQLQEAARERLAQGDRFAVLALDLDEFKSVNDTFGHAAGDKLLKSVAERLRSFEASDVQ
HHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
LARLAGDEFAVLATGRSARDLHAIEALANGIVEALASPFTIDGIRLTVSVSIGIAIAPQD
EEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEEEEEEECCCH
GCQEIMRRADLALYRMKSEGRNGYRFYEAEMDERIEARRALTADLRGALDRDEFVLYFQP
HHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
IVAAKECRVRGFEALIRWKHPVRGFVSPGEFIPLAEETGVIIPLGEWILREACRIAAGWP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHHHHHCCCCC
GDVRIAVNLSPRQFRHSDLTQLVRSALRTSGLAAARLELEVTESVFLEATPAINATLSKL
CCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHEECCCCHHHHHHHH
REMGVRLSLDDFGTGYSSLSYLRRIAFDKIKIDQSFVRDLPQERGAAAIVSAIIDMATSL
HHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHCC
DMTITAEGVETDAQRACLLEQGCHEFQGYLFSKPLPAEQAAALARSRQLLPAAVRAA
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLISFLIDTDRKADPLDANLRARARVEQLDVALRLVPFTILVSLSVVQVIVYLFWNPANR
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AYLAGLETLILPLAVVSLQQCWRWRSRPKPLQVPSSFVQGVVLAAQAYGFLLASIPVMLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SGADAHGRLLIASSIAGLIATGMSAAVLPRVAIGYSGLIILGSFIALATTGEAFYIYVAV
CCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
LLFFYAIFICFTILHLSRLLTMRVIAQIELERQQEFTHLLLNEFEESASDWLWETDADLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LQHVSPRLIEVAGSSERQLMGLPLERLLLPPVAPPRSHSSTTLWSCIAERRAFRNLHLQL
EECCCCCEEEECCCCCCEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEE
DIAGERRTWCLSGKPTFDRAGAFSGYRGVGSDVTEKRRSEERLSYLALHDSLTDLPNRVL
EECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHQLQEAARERLAQGDRFAVLALDLDEFKSVNDTFGHAAGDKLLKSVAERLRSFEASDVQ
HHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
LARLAGDEFAVLATGRSARDLHAIEALANGIVEALASPFTIDGIRLTVSVSIGIAIAPQD
EEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEEEEEEECCCH
GCQEIMRRADLALYRMKSEGRNGYRFYEAEMDERIEARRALTADLRGALDRDEFVLYFQP
HHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
IVAAKECRVRGFEALIRWKHPVRGFVSPGEFIPLAEETGVIIPLGEWILREACRIAAGWP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHHHHHCCCCC
GDVRIAVNLSPRQFRHSDLTQLVRSALRTSGLAAARLELEVTESVFLEATPAINATLSKL
CCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHEECCCCHHHHHHHH
REMGVRLSLDDFGTGYSSLSYLRRIAFDKIKIDQSFVRDLPQERGAAAIVSAIIDMATSL
HHCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHCC
DMTITAEGVETDAQRACLLEQGCHEFQGYLFSKPLPAEQAAALARSRQLLPAAVRAA
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]