BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is gudP [H]

Identifier: 170749322

GI number: 170749322

Start: 3072346

End: 3073638

Strand: Reverse

Name: gudP [H]

Synonym: Mrad2831_2915

Alternate gene names: 170749322

Gene position: 3073638-3072346 (Counterclockwise)

Preceding gene: 170749323

Following gene: 170749321

Centisome position: 50.57

GC content: 68.68

Gene sequence:

>1293_bases
ATGTCGAAGCGCTTCAGCGCCACGAACGGCGTGCTCGGCCTGCTCTGTGTGATGTACTTCATCACCTATCTGGACCGGGT
GAACATCGCCACGGCCGGCGCGGAGATCATGCGCGATTTCGGCATGTCGAAGACCGATTTCGGTCTGATCCTGTCGGCCT
TCGCCTACCCGTACGCGATCTTCCAGGTGATCGGCGGGTCGGTCGGCGACAAGTTCGGCGCCCGGCGCACGCTGCTCGCC
TGCGGGGTGATCTGGGCCTCGGCGACCATCCTGACCGGCATGGTCGGCGGTCTCGTGAGCCTGTTCTTGGCCCGGGTGCT
GCTCGGCTTCGGCGAGGGCGCGACCTTCCCGACCGCCACCCGCGCCATGCAGAACTGGACGGCGCCCGGCCGGCGCGGCT
TCGCGCAGGGCATCACCCACGCCTTCGCGCGGCTCGGCAACGCGGTGGCGCCCCCGATCGTCGCCTTCCTGATCTACCAT
TTCGGCTGGCGGACCAGCTTCGTGATCCTCGGCGCGGTGAGCTTCGTCTGGGTCGCGATCTGGTGGCTGTACTTCCGTGA
CGACCCGTCCGAGCATCCGGCGATCACCAAGGCGGAGCTCGACACGCTGCCGCCGCCCCGCAAGGTCGGCGCGAAGCAGA
GCGTGCCGTGGGGCGCCCTGACCCGCCGCATGCTGCCGGTCTCCATCACGTATTTCTGCTACGGCTGGACCCTGTGGCTG
TTCCTCGGCTGGCTCCCGAGCTTCTTCAAGGAGAACTACAGCCTCGACCTGAAGAACTCGGCCCTGTTCGCCTCGGGCGT
GTTCTTCGCGGGCGTCGTCGGCGACACGGTCGGCGGCATGCTCAGCGACTCGATCCTGCACCGCACCGGCAACGTGAAGC
TCGCGCGCCTGTCGGTGATCGTGATCGGCTTCCTCGGGGCCGCCGCCAGCCTCGCCGGCGTGTTCATGACGCGGGACCTG
ACGCTCGTGGCGCTGCTCCTGTCCTCCGGCTTCTTCTTCGCCGAGCTCGTGATCGGACCGATCTGGTCCGTGCCGATGGA
TATCGCGCCGAAATATGCCGGGACCGCCAGCGGGCTGATGAACACCGGCTCGGCCGTGGCGGCGATCGTCTCGCCGATCG
TCTTCGGCGTCATCGTGGACGCGACCGGGAGCTGGACGCTGCCCTTCGTCGGCTCGATCGGCCTGTGCCTGCTCGGCGCC
GCGCTGGCCTTCACCATGCACCCCGAGCGGGAGTTCGTGGATCCCGTCACGCCGCCGGTCGCCCCCGCGGCCACCGTGCC
GGCCGGGGAGTAG

Upstream 100 bases:

>100_bases
TCGCAACGCGTTTGAATAATGCATTACGAGAAGGTGCCCGGCCGCGACGCCGAGGCGCCCGGCGACCGCGAGAGGCGGCG
CCCCATGGGAGGAACGGTCG

Downstream 100 bases:

>100_bases
GGCGCGATGGCGGAAACGATGAAGCGGTCGGGCCCGCTCGCCGGGATGCGGGTGATCGAGCTCGCCCACATCATGGCCGG
GCCGGTCTGCGGGTTGATGC

Product: major facilitator transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSKRFSATNGVLGLLCVMYFITYLDRVNIATAGAEIMRDFGMSKTDFGLILSAFAYPYAIFQVIGGSVGDKFGARRTLLA
CGVIWASATILTGMVGGLVSLFLARVLLGFGEGATFPTATRAMQNWTAPGRRGFAQGITHAFARLGNAVAPPIVAFLIYH
FGWRTSFVILGAVSFVWVAIWWLYFRDDPSEHPAITKAELDTLPPPRKVGAKQSVPWGALTRRMLPVSITYFCYGWTLWL
FLGWLPSFFKENYSLDLKNSALFASGVFFAGVVGDTVGGMLSDSILHRTGNVKLARLSVIVIGFLGAAASLAGVFMTRDL
TLVALLLSSGFFFAELVIGPIWSVPMDIAPKYAGTASGLMNTGSAVAAIVSPIVFGVIVDATGSWTLPFVGSIGLCLLGA
ALAFTMHPEREFVDPVTPPVAPAATVPAGE

Sequences:

>Translated_430_residues
MSKRFSATNGVLGLLCVMYFITYLDRVNIATAGAEIMRDFGMSKTDFGLILSAFAYPYAIFQVIGGSVGDKFGARRTLLA
CGVIWASATILTGMVGGLVSLFLARVLLGFGEGATFPTATRAMQNWTAPGRRGFAQGITHAFARLGNAVAPPIVAFLIYH
FGWRTSFVILGAVSFVWVAIWWLYFRDDPSEHPAITKAELDTLPPPRKVGAKQSVPWGALTRRMLPVSITYFCYGWTLWL
FLGWLPSFFKENYSLDLKNSALFASGVFFAGVVGDTVGGMLSDSILHRTGNVKLARLSVIVIGFLGAAASLAGVFMTRDL
TLVALLLSSGFFFAELVIGPIWSVPMDIAPKYAGTASGLMNTGSAVAAIVSPIVFGVIVDATGSWTLPFVGSIGLCLLGA
ALAFTMHPEREFVDPVTPPVAPAATVPAGE
>Mature_429_residues
SKRFSATNGVLGLLCVMYFITYLDRVNIATAGAEIMRDFGMSKTDFGLILSAFAYPYAIFQVIGGSVGDKFGARRTLLAC
GVIWASATILTGMVGGLVSLFLARVLLGFGEGATFPTATRAMQNWTAPGRRGFAQGITHAFARLGNAVAPPIVAFLIYHF
GWRTSFVILGAVSFVWVAIWWLYFRDDPSEHPAITKAELDTLPPPRKVGAKQSVPWGALTRRMLPVSITYFCYGWTLWLF
LGWLPSFFKENYSLDLKNSALFASGVFFAGVVGDTVGGMLSDSILHRTGNVKLARLSVIVIGFLGAAASLAGVFMTRDLT
LVALLLSSGFFFAELVIGPIWSVPMDIAPKYAGTASGLMNTGSAVAAIVSPIVFGVIVDATGSWTLPFVGSIGLCLLGAA
LAFTMHPEREFVDPVTPPVAPAATVPAGE

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=399, Percent_Identity=26.8170426065163, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI6912666, Length=386, Percent_Identity=26.4248704663212, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI9966811, Length=396, Percent_Identity=22.7272727272727, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21322234, Length=361, Percent_Identity=25.207756232687, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI9945322, Length=367, Percent_Identity=23.9782016348774, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI148743791, Length=290, Percent_Identity=23.7931034482759, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4885441, Length=358, Percent_Identity=24.5810055865922, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI148728191, Length=263, Percent_Identity=24.3346007604563, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI223718438, Length=170, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI154800443, Length=364, Percent_Identity=22.2527472527473, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=28.1818181818182, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789515, Length=416, Percent_Identity=29.0865384615385, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI2367379, Length=404, Percent_Identity=28.7128712871287, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI87082320, Length=391, Percent_Identity=28.3887468030691, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI2367193, Length=373, Percent_Identity=26.0053619302949, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082310, Length=285, Percent_Identity=24.5614035087719, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=364, Percent_Identity=28.8461538461538, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17535049, Length=403, Percent_Identity=26.0545905707196, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI115533554, Length=390, Percent_Identity=25.8974358974359, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115533556, Length=390, Percent_Identity=25.8974358974359, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17554148, Length=360, Percent_Identity=26.3888888888889, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17554962, Length=415, Percent_Identity=23.1325301204819, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71997452, Length=379, Percent_Identity=23.2189973614776, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569727, Length=379, Percent_Identity=24.802110817942, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=373, Percent_Identity=23.0563002680965, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=349, Percent_Identity=23.4957020057307, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=332, Percent_Identity=24.0963855421687, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25151055, Length=348, Percent_Identity=21.264367816092, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=223, Percent_Identity=24.2152466367713, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=220, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25141341, Length=295, Percent_Identity=22.7118644067797, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=295, Percent_Identity=22.7118644067797, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17570335, Length=347, Percent_Identity=21.3256484149856, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=296, Percent_Identity=21.9594594594595, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648416, Length=392, Percent_Identity=28.3163265306122, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356189, Length=392, Percent_Identity=28.3163265306122, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573708, Length=394, Percent_Identity=26.3959390862944, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573707, Length=394, Percent_Identity=26.3959390862944, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=25.2747252747253, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45550460, Length=414, Percent_Identity=24.6376811594203, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641682, Length=420, Percent_Identity=23.0952380952381, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655255, Length=371, Percent_Identity=23.7196765498652, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24658674, Length=416, Percent_Identity=23.7980769230769, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583789, Length=366, Percent_Identity=25.1366120218579, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24580790, Length=375, Percent_Identity=24.5333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920686, Length=387, Percent_Identity=25.3229974160207, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639764, Length=403, Percent_Identity=23.3250620347395, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658666, Length=405, Percent_Identity=23.7037037037037, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573299, Length=397, Percent_Identity=25.6926952141058, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI62484226, Length=414, Percent_Identity=24.6376811594203, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24658658, Length=412, Percent_Identity=24.0291262135922, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45550495, Length=421, Percent_Identity=22.5653206650831, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655271, Length=453, Percent_Identity=23.841059602649, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130135, Length=427, Percent_Identity=24.1217798594848, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654215, Length=382, Percent_Identity=24.869109947644, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19922400, Length=382, Percent_Identity=24.869109947644, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20130167, Length=360, Percent_Identity=23.6111111111111, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20129235, Length=365, Percent_Identity=26.8493150684932, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281361682, Length=350, Percent_Identity=21.4285714285714, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658689, Length=454, Percent_Identity=21.5859030837004, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550364, Length=407, Percent_Identity=21.8673218673219, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552797, Length=361, Percent_Identity=22.4376731301939, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653727, Length=416, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45897; Mature: 45766

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCC
>Mature Secondary Structure 
SKRFSATNGVLGLLCVMYFITYLDRVNIATAGAEIMRDFGMSKTDFGLILSAFAYPYAI
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FQVIGGSVGDKFGARRTLLACGVIWASATILTGMVGGLVSLFLARVLLGFGEGATFPTAT
HHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RAMQNWTAPGRRGFAQGITHAFARLGNAVAPPIVAFLIYHFGWRTSFVILGAVSFVWVAI
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWLYFRDDPSEHPAITKAELDTLPPPRKVGAKQSVPWGALTRRMLPVSITYFCYGWTLWL
HHHHHCCCCCCCCCCCHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLGWLPSFFKENYSLDLKNSALFASGVFFAGVVGDTVGGMLSDSILHRTGNVKLARLSVI
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHH
VIGFLGAAASLAGVFMTRDLTLVALLLSSGFFFAELVIGPIWSVPMDIAPKYAGTASGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHH
NTGSAVAAIVSPIVFGVIVDATGSWTLPFVGSIGLCLLGAALAFTMHPEREFVDPVTPPV
CCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
APAATVPAGE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]