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The map label for this gene is arcB [C]

Identifier: 170749193

GI number: 170749193

Start: 2924406

End: 2926289

Strand: Reverse

Name: arcB [C]

Synonym: Mrad2831_2786

Alternate gene names: 170749193

Gene position: 2926289-2924406 (Counterclockwise)

Preceding gene: 170749195

Following gene: 170749192

Centisome position: 48.15

GC content: 71.5

Gene sequence:

>1884_bases
ATGGTCCATACTGGCTACAACCCGGCGCTGGTCGCCCTGTCGATCGGCCTCGCCGTCTTCGCGTCCTACACCGCGCTGGA
CCTGGGGGCGCGGATCCGCGGGCCCGTCGCGGGGCCGCGCTGGCCATGGATCGCCGGTGCCGCACTCGCCATGGGCGGCG
GCATCTGGTCGATGCACTTCGTCGGCATGCTGGCCTTCGAGATGGGCATGCCGGCCGCCTACGACATCGGCCTCACCCTC
CTGTCTCTCGCGATCGCCGTCGCGGTGACCGGGGCCGCCTTCCTGTGGGTGGCGCGCGTCGGCGAGGGGCCGGGCGGACT
TCTCGTGGCCGGCCCCCTGATGGGTCTGGGCGTCGCCGGCATGCATTACACCGGCATGGCGGCGCTCCGGATCCCGGGCG
ACCTCGCCTACAGCCCGGCGGTGGTCGCGCTCTCGGTGGCGATCGCCGTGACCGCGGCGACCGCGGCCCTGTGGCTCTCC
TTCCGGCAGCACGGCGTCTGGCAGAAGCTCGCCGCGGCGTGTGTGATGGGCCTCGCGGTGGCGGGGATGCACTACACCGG
CATGGCCGCGGCGACGATCACCGTCGAGGCGGCCGGCGCCCACGCCGCCCACGCGGCCACCGGCGTTCCGGGCCAGCAGA
ACCTCGCCCTCTACGTCGCCGGCGCGACGTTCCTCATCCTGTTCCTCGCGATGCTCGCCTCCTCGCTGGACCAGCAGCGC
GTGCAGCGCGAACTCCAGGCGAGCGAGGCGCGGTTCCGCGCCGCCGTGCAGGCGGTGCGCGGCGTGCTCTGGACCAACGA
TGCCGAGGGCCGGATGCTCGGCGAGCAGCCGGGCTGGAGCGCGATCACCGGTCAGACGCGGGACCAGTATCAGGGCTACG
GCTGGGCCGACGCGGTCCATCCCGACGACATGGAATCGTCCATCGAGACCTGGAACGCGACCGTCCGGGCACGGCGTACC
TACGTCCACGAGCACCGGGTCCGGTCCCGCGACGGAACGTGGCGACATTTCGCGATCCGCGCCATCCCGGTCTTCGACGC
GCGGGGCGAGATCCGCGAGTGGGTCGGCGTCCACACGGACATCACCGAGCAGAGACTGGCCGAATCCGATCTGCGCGAGT
CCAACGAGGAGATCCAGCGCTACGCCTACATCGTCAGCCACGACCTCCGCGCGCCGCTGGTCAACGTGATGGGATTCACG
AGCGAACTGGAGGCGACCCGGACCGAGATCGCCGCGGCCCTCCGGGGACATCCGGAGGCGGATCGGCTCGACGCCGATCT
CGGCGAGGCGCTCGGCTTCATCAAGGCGGCGGTGAACCGGATGGAAGGGCTGATCGCCGCCATCCTGAAGCTCTCGCGGG
AGGGGCGGCGACAGTTCTCGCCCGAGCCCCTCGACATGTCCGGCCTGCTGCGCGGCGTGGCCGATGCCCAGCGGCATCAG
GCGGAGGCGGTCGGCGCCACGGTGACGATCGCCCGCGACCTGCCCGAGATCGTCGCCGACCGGCTCGCGATCGAGCAGGT
CTTCGGCAACCTGCTGGACAACGCCGTGAAATACCTCGACCCGAGTCGGCCCGGACGCATCACCGTGACGGCCAAGGCCG
TGGGCGAGCGCGGCGTCTGCTTCTCCGTCGCCGACAACGGTCGGGGCATCGCCGCCCGGGACCACGCCCGCGTCTTCGAG
CTTTTCCGCCGATCGGGCACACAGGACCGCCCGGGCGAGGGGATCGGCCTGGCCCACGTGAAGGCGCTGGTGCGCTCGTT
CGGCGGCCGGATCGAGATCCGTTCAGAACTCGGCGTCGGCACGACGTTCGACGTGACCTTGCCGCGCGGGACAGCTACAG
CGGTCCGGTTAGACCCTGAACCGGCGCCCATCGCCGCCGAATGA

Upstream 100 bases:

>100_bases
TCGGTATCTCGGAGACTTGGCCGGCTCCGAATCGCGATGGCGCCCGCCATCTACCCGGGATACATCGCGAGGAGCGCCCC
TCACGCGTCGATCGCAGTCG

Downstream 100 bases:

>100_bases
GCGTGGAGCCGCCCGTGCACCCCGTCAGCATCGTGATGATCGAGGATGACGAGGGACATGCGCGCCTGATCGAGCGGAAC
ATTCGCCGCGCCGGCGTCAA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MVHTGYNPALVALSIGLAVFASYTALDLGARIRGPVAGPRWPWIAGAALAMGGGIWSMHFVGMLAFEMGMPAAYDIGLTL
LSLAIAVAVTGAAFLWVARVGEGPGGLLVAGPLMGLGVAGMHYTGMAALRIPGDLAYSPAVVALSVAIAVTAATAALWLS
FRQHGVWQKLAAACVMGLAVAGMHYTGMAAATITVEAAGAHAAHAATGVPGQQNLALYVAGATFLILFLAMLASSLDQQR
VQRELQASEARFRAAVQAVRGVLWTNDAEGRMLGEQPGWSAITGQTRDQYQGYGWADAVHPDDMESSIETWNATVRARRT
YVHEHRVRSRDGTWRHFAIRAIPVFDARGEIREWVGVHTDITEQRLAESDLRESNEEIQRYAYIVSHDLRAPLVNVMGFT
SELEATRTEIAAALRGHPEADRLDADLGEALGFIKAAVNRMEGLIAAILKLSREGRRQFSPEPLDMSGLLRGVADAQRHQ
AEAVGATVTIARDLPEIVADRLAIEQVFGNLLDNAVKYLDPSRPGRITVTAKAVGERGVCFSVADNGRGIAARDHARVFE
LFRRSGTQDRPGEGIGLAHVKALVRSFGGRIEIRSELGVGTTFDVTLPRGTATAVRLDPEPAPIAAE

Sequences:

>Translated_627_residues
MVHTGYNPALVALSIGLAVFASYTALDLGARIRGPVAGPRWPWIAGAALAMGGGIWSMHFVGMLAFEMGMPAAYDIGLTL
LSLAIAVAVTGAAFLWVARVGEGPGGLLVAGPLMGLGVAGMHYTGMAALRIPGDLAYSPAVVALSVAIAVTAATAALWLS
FRQHGVWQKLAAACVMGLAVAGMHYTGMAAATITVEAAGAHAAHAATGVPGQQNLALYVAGATFLILFLAMLASSLDQQR
VQRELQASEARFRAAVQAVRGVLWTNDAEGRMLGEQPGWSAITGQTRDQYQGYGWADAVHPDDMESSIETWNATVRARRT
YVHEHRVRSRDGTWRHFAIRAIPVFDARGEIREWVGVHTDITEQRLAESDLRESNEEIQRYAYIVSHDLRAPLVNVMGFT
SELEATRTEIAAALRGHPEADRLDADLGEALGFIKAAVNRMEGLIAAILKLSREGRRQFSPEPLDMSGLLRGVADAQRHQ
AEAVGATVTIARDLPEIVADRLAIEQVFGNLLDNAVKYLDPSRPGRITVTAKAVGERGVCFSVADNGRGIAARDHARVFE
LFRRSGTQDRPGEGIGLAHVKALVRSFGGRIEIRSELGVGTTFDVTLPRGTATAVRLDPEPAPIAAE
>Mature_627_residues
MVHTGYNPALVALSIGLAVFASYTALDLGARIRGPVAGPRWPWIAGAALAMGGGIWSMHFVGMLAFEMGMPAAYDIGLTL
LSLAIAVAVTGAAFLWVARVGEGPGGLLVAGPLMGLGVAGMHYTGMAALRIPGDLAYSPAVVALSVAIAVTAATAALWLS
FRQHGVWQKLAAACVMGLAVAGMHYTGMAAATITVEAAGAHAAHAATGVPGQQNLALYVAGATFLILFLAMLASSLDQQR
VQRELQASEARFRAAVQAVRGVLWTNDAEGRMLGEQPGWSAITGQTRDQYQGYGWADAVHPDDMESSIETWNATVRARRT
YVHEHRVRSRDGTWRHFAIRAIPVFDARGEIREWVGVHTDITEQRLAESDLRESNEEIQRYAYIVSHDLRAPLVNVMGFT
SELEATRTEIAAALRGHPEADRLDADLGEALGFIKAAVNRMEGLIAAILKLSREGRRQFSPEPLDMSGLLRGVADAQRHQ
AEAVGATVTIARDLPEIVADRLAIEQVFGNLLDNAVKYLDPSRPGRITVTAKAVGERGVCFSVADNGRGIAARDHARVFE
LFRRSGTQDRPGEGIGLAHVKALVRSFGGRIEIRSELGVGTTFDVTLPRGTATAVRLDPEPAPIAAE

Specific function: Member Of The Two-Component Regulatory System Arcb/Arca. Sensor-Regulator Protein For Anaerobic Repression Of The Arc Modulon. Activates Arca Via A Four-Step Phosphorelay. Arcb Can Also Dephosphorylate Arca By A Reverse Phosphorelay Involving His- 717 And

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=380, Percent_Identity=23.9473684210526, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789149, Length=268, Percent_Identity=27.6119402985075, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=28.3842794759825, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=27.007299270073, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=28.6219081272085, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=28.8617886178862, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=27.2, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=27.5303643724696, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=29.1512915129151, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 66904; Mature: 66904

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50924 MHYT ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHTGYNPALVALSIGLAVFASYTALDLGARIRGPVAGPRWPWIAGAALAMGGGIWSMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
VGMLAFEMGMPAAYDIGLTLLSLAIAVAVTGAAFLWVARVGEGPGGLLVAGPLMGLGVAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCCC
MHYTGMAALRIPGDLAYSPAVVALSVAIAVTAATAALWLSFRQHGVWQKLAAACVMGLAV
CHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGMHYTGMAAATITVEAAGAHAAHAATGVPGQQNLALYVAGATFLILFLAMLASSLDQQR
HCCHHCCEEEEEEEEEECCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
VQRELQASEARFRAAVQAVRGVLWTNDAEGRMLGEQPGWSAITGQTRDQYQGYGWADAVH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
PDDMESSIETWNATVRARRTYVHEHRVRSRDGTWRHFAIRAIPVFDARGEIREWVGVHTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHCCCCC
ITEQRLAESDLRESNEEIQRYAYIVSHDLRAPLVNVMGFTSELEATRTEIAAALRGHPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
DRLDADLGEALGFIKAAVNRMEGLIAAILKLSREGRRQFSPEPLDMSGLLRGVADAQRHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AEAVGATVTIARDLPEIVADRLAIEQVFGNLLDNAVKYLDPSRPGRITVTAKAVGERGVC
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCE
FSVADNGRGIAARDHARVFELFRRSGTQDRPGEGIGLAHVKALVRSFGGRIEIRSELGVG
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCC
TTFDVTLPRGTATAVRLDPEPAPIAAE
CEEEEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MVHTGYNPALVALSIGLAVFASYTALDLGARIRGPVAGPRWPWIAGAALAMGGGIWSMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
VGMLAFEMGMPAAYDIGLTLLSLAIAVAVTGAAFLWVARVGEGPGGLLVAGPLMGLGVAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCCC
MHYTGMAALRIPGDLAYSPAVVALSVAIAVTAATAALWLSFRQHGVWQKLAAACVMGLAV
CHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGMHYTGMAAATITVEAAGAHAAHAATGVPGQQNLALYVAGATFLILFLAMLASSLDQQR
HCCHHCCEEEEEEEEEECCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
VQRELQASEARFRAAVQAVRGVLWTNDAEGRMLGEQPGWSAITGQTRDQYQGYGWADAVH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
PDDMESSIETWNATVRARRTYVHEHRVRSRDGTWRHFAIRAIPVFDARGEIREWVGVHTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHCCCCC
ITEQRLAESDLRESNEEIQRYAYIVSHDLRAPLVNVMGFTSELEATRTEIAAALRGHPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
DRLDADLGEALGFIKAAVNRMEGLIAAILKLSREGRRQFSPEPLDMSGLLRGVADAQRHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AEAVGATVTIARDLPEIVADRLAIEQVFGNLLDNAVKYLDPSRPGRITVTAKAVGERGVC
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCE
FSVADNGRGIAARDHARVFELFRRSGTQDRPGEGIGLAHVKALVRSFGGRIEIRSELGVG
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCC
TTFDVTLPRGTATAVRLDPEPAPIAAE
CEEEEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]