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The map label for this gene is yciR [C]

Identifier: 170748846

GI number: 170748846

Start: 2591407

End: 2593014

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_2428

Alternate gene names: 170748846

Gene position: 2593014-2591407 (Counterclockwise)

Preceding gene: 170748847

Following gene: 170748844

Centisome position: 42.66

GC content: 70.58

Gene sequence:

>1608_bases
ATGTTTCGCGCTGACGCTGGAAACCGGGTCCTGACCATGCCGATCGAGACGTCGAAAGCTTGGGGCCGCGGCGAGCTGTA
CGAGACCCTGTGCCTGCTCGTGATCGGCGTCGGGATCTGGTTCGTCGGCGTCACGCTGGGGACCTTCGCGTATCTCAACA
CCCTGGTCGCCACCTACAACCTCACGGATCTCCTCCTGCTCGCCGCCTGCATGGGCGTGGCGCAGTGGGGCGCCAGCATC
CGCAAGTCGATCATCCTCCGGCGGCTCATGCTCGAGCGCGCCGCCGCGGCGGCGCAGGCCGAGGCGATCGCCCGGCACGA
CGGGCTGACCGGTCTCGCGAACCGCCGCCGCTTCATCGACGCCGTGGAGCGGGCGCACGCGTCGGGCGCCGGGGACGCGG
CGGTGCTGCTCATCGACCTCGACCGGTTCAAGCCGGTCAACGACCTCTACGGCCACGCGGCCGGGAACGCGGTCCTGTGC
GCCGTGGCCGAGCGCCTCCAGCAGCTCGTGCCGTCGGGCGGCCTGGCGGCCCGGCTGGGCGGCGACGAGTTCGCCATGCT
GGTCCCGCTCCGCTACGAGAGCGAGGCGCTGAGGCGTCTCGCCCAGGCGGTCATCGGGCGCATCGCCGAGCCGGTGACGT
GGAGCCAGAACGACCTCAAGGTCGGCGCGACGGTCGGCGTCGCCGCGGTGTCGGCCGAGCACGGGGACGCCGACGCGATC
CTGCACGCGGCCGACCTCGCCATGTACCAGGGCAAGAAGGACGGGCGCGGCAATTTCCGGTTCTTCCGCAGCGCCATGGA
CGCGGAGCTGCGCGCCCGCGCCCGCATGGAGACGGAACTCCGCGGCGCCATCGAGACGGGCGCGATCGAGCCCTTCTACC
AGCCGGTGGTGTCGCTCCCCGAGCGGGAGATCGTCGGCGTCGAGGTGCTGGCGCGCTGGCGCCACCCGTCGCGCGGGCTG
GTCGGACCGAGCGAGTTCATCCCGGTGGCCGAGGAGACCGGGATGATCGCGGATCTCAGCTACACGTTGATCCGCCGCGC
GTGCCTGGATGCCCGCGCCTGGCCGCCCCACCTGATCCTGGCGGTGAACATCGCCCCGCAGCAGTTCCAGGACGCGTGGC
TCGCCCAGCGCATCCTGGGGATCCTGACCGAGACCGGCTTCCCGCCGCAGCGCCTGGAGGTCGAGATCACCGAGAGTGCT
CTGATCCAGGACCTGGAGGCGACACGGACGACCCTGCTGTCCCTGCGCGAACTCGGCGTGCGCATCGCGCTGGACGATTT
CGGTACCGGCTATTCCAGCCTGTACCACCTGCGCGAACTCAAGTTCGACAAGCTGAAGATCGACCGCAGCTACGTGGACG
CCATCACGATGAGCGACGAGCGGGCGAAGCTGGTCGACGCCATCATCAAGCTCGGGGCGAGCCTCGGCCTCTCCACCACC
GCCGAGGGGATCGAGACCGACGCCAGCCTCGACTGGCTGTCCGACCAGGGCTGCCATTTCGGCCAGGGCTACCTGTTCGG
CCACGCCATGCCGAAGGCCGAGATGGACGACGTGCTCGCCGCCGCGCGATCCCCGGCCCCGTTCCCGGATCTGGCGCGGG
CCTCGTGA

Upstream 100 bases:

>100_bases
AGTGCAGGCATTAATTCAAATTAAACCAAGACAAAGTCACGTAACGATGTAGATAGGCGCCCGCGTCCGGAGGCTGTTTT
ACAGCGCATGAGCGGACAGC

Downstream 100 bases:

>100_bases
GGCGTGGGACGCCGCCCGCGCGGCGTCGCGCGGGTCAGCGCGGCGCCCGGTAGGCGGAGCCGTCGGCGGCCCCGAGCGGG
TGCTCCACGAACCGGCCCGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MFRADAGNRVLTMPIETSKAWGRGELYETLCLLVIGVGIWFVGVTLGTFAYLNTLVATYNLTDLLLLAACMGVAQWGASI
RKSIILRRLMLERAAAAAQAEAIARHDGLTGLANRRRFIDAVERAHASGAGDAAVLLIDLDRFKPVNDLYGHAAGNAVLC
AVAERLQQLVPSGGLAARLGGDEFAMLVPLRYESEALRRLAQAVIGRIAEPVTWSQNDLKVGATVGVAAVSAEHGDADAI
LHAADLAMYQGKKDGRGNFRFFRSAMDAELRARARMETELRGAIETGAIEPFYQPVVSLPEREIVGVEVLARWRHPSRGL
VGPSEFIPVAEETGMIADLSYTLIRRACLDARAWPPHLILAVNIAPQQFQDAWLAQRILGILTETGFPPQRLEVEITESA
LIQDLEATRTTLLSLRELGVRIALDDFGTGYSSLYHLRELKFDKLKIDRSYVDAITMSDERAKLVDAIIKLGASLGLSTT
AEGIETDASLDWLSDQGCHFGQGYLFGHAMPKAEMDDVLAAARSPAPFPDLARAS

Sequences:

>Translated_535_residues
MFRADAGNRVLTMPIETSKAWGRGELYETLCLLVIGVGIWFVGVTLGTFAYLNTLVATYNLTDLLLLAACMGVAQWGASI
RKSIILRRLMLERAAAAAQAEAIARHDGLTGLANRRRFIDAVERAHASGAGDAAVLLIDLDRFKPVNDLYGHAAGNAVLC
AVAERLQQLVPSGGLAARLGGDEFAMLVPLRYESEALRRLAQAVIGRIAEPVTWSQNDLKVGATVGVAAVSAEHGDADAI
LHAADLAMYQGKKDGRGNFRFFRSAMDAELRARARMETELRGAIETGAIEPFYQPVVSLPEREIVGVEVLARWRHPSRGL
VGPSEFIPVAEETGMIADLSYTLIRRACLDARAWPPHLILAVNIAPQQFQDAWLAQRILGILTETGFPPQRLEVEITESA
LIQDLEATRTTLLSLRELGVRIALDDFGTGYSSLYHLRELKFDKLKIDRSYVDAITMSDERAKLVDAIIKLGASLGLSTT
AEGIETDASLDWLSDQGCHFGQGYLFGHAMPKAEMDDVLAAARSPAPFPDLARAS
>Mature_535_residues
MFRADAGNRVLTMPIETSKAWGRGELYETLCLLVIGVGIWFVGVTLGTFAYLNTLVATYNLTDLLLLAACMGVAQWGASI
RKSIILRRLMLERAAAAAQAEAIARHDGLTGLANRRRFIDAVERAHASGAGDAAVLLIDLDRFKPVNDLYGHAAGNAVLC
AVAERLQQLVPSGGLAARLGGDEFAMLVPLRYESEALRRLAQAVIGRIAEPVTWSQNDLKVGATVGVAAVSAEHGDADAI
LHAADLAMYQGKKDGRGNFRFFRSAMDAELRARARMETELRGAIETGAIEPFYQPVVSLPEREIVGVEVLARWRHPSRGL
VGPSEFIPVAEETGMIADLSYTLIRRACLDARAWPPHLILAVNIAPQQFQDAWLAQRILGILTETGFPPQRLEVEITESA
LIQDLEATRTTLLSLRELGVRIALDDFGTGYSSLYHLRELKFDKLKIDRSYVDAITMSDERAKLVDAIIKLGASLGLSTT
AEGIETDASLDWLSDQGCHFGQGYLFGHAMPKAEMDDVLAAARSPAPFPDLARAS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=428, Percent_Identity=34.3457943925234, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=29.4663573085847, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=34.3220338983051, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081743, Length=252, Percent_Identity=35.7142857142857, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=36.3265306122449, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI226510982, Length=411, Percent_Identity=27.4939172749392, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788502, Length=260, Percent_Identity=34.6153846153846, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787055, Length=264, Percent_Identity=32.1969696969697, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=32.1888412017167, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=32.156862745098, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=28.9156626506024, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788381, Length=427, Percent_Identity=27.4004683840749, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=36.6863905325444, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081977, Length=185, Percent_Identity=36.7567567567568, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=33.5443037974684, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=29.045643153527, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI145693134, Length=176, Percent_Identity=32.3863636363636, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=37.5757575757576, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786584, Length=167, Percent_Identity=31.7365269461078, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=233, Percent_Identity=29.6137339055794, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787410, Length=132, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789650, Length=425, Percent_Identity=21.4117647058824, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082007, Length=204, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 58145; Mature: 58145

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRADAGNRVLTMPIETSKAWGRGELYETLCLLVIGVGIWFVGVTLGTFAYLNTLVATYN
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDLLLLAACMGVAQWGASIRKSIILRRLMLERAAAAAQAEAIARHDGLTGLANRRRFID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVERAHASGAGDAAVLLIDLDRFKPVNDLYGHAAGNAVLCAVAERLQQLVPSGGLAARLG
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
GDEFAMLVPLRYESEALRRLAQAVIGRIAEPVTWSQNDLKVGATVGVAAVSAEHGDADAI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCHHHH
LHAADLAMYQGKKDGRGNFRFFRSAMDAELRARARMETELRGAIETGAIEPFYQPVVSLP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
EREIVGVEVLARWRHPSRGLVGPSEFIPVAEETGMIADLSYTLIRRACLDARAWPPHLIL
CCHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
AVNIAPQQFQDAWLAQRILGILTETGFPPQRLEVEITESALIQDLEATRTTLLSLRELGV
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
RIALDDFGTGYSSLYHLRELKFDKLKIDRSYVDAITMSDERAKLVDAIIKLGASLGLSTT
EEEEECCCCCHHHHHHHHHCCHHHHHHCHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCC
AEGIETDASLDWLSDQGCHFGQGYLFGHAMPKAEMDDVLAAARSPAPFPDLARAS
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFRADAGNRVLTMPIETSKAWGRGELYETLCLLVIGVGIWFVGVTLGTFAYLNTLVATYN
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDLLLLAACMGVAQWGASIRKSIILRRLMLERAAAAAQAEAIARHDGLTGLANRRRFID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVERAHASGAGDAAVLLIDLDRFKPVNDLYGHAAGNAVLCAVAERLQQLVPSGGLAARLG
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEC
GDEFAMLVPLRYESEALRRLAQAVIGRIAEPVTWSQNDLKVGATVGVAAVSAEHGDADAI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCHHHH
LHAADLAMYQGKKDGRGNFRFFRSAMDAELRARARMETELRGAIETGAIEPFYQPVVSLP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
EREIVGVEVLARWRHPSRGLVGPSEFIPVAEETGMIADLSYTLIRRACLDARAWPPHLIL
CCHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
AVNIAPQQFQDAWLAQRILGILTETGFPPQRLEVEITESALIQDLEATRTTLLSLRELGV
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
RIALDDFGTGYSSLYHLRELKFDKLKIDRSYVDAITMSDERAKLVDAIIKLGASLGLSTT
EEEEECCCCCHHHHHHHHHCCHHHHHHCHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCC
AEGIETDASLDWLSDQGCHFGQGYLFGHAMPKAEMDDVLAAARSPAPFPDLARAS
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]