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The map label for this gene is murG

Identifier: 170748774

GI number: 170748774

Start: 2492742

End: 2493851

Strand: Reverse

Name: murG

Synonym: Mrad2831_2356

Alternate gene names: 170748774

Gene position: 2493851-2492742 (Counterclockwise)

Preceding gene: 170748775

Following gene: 170748773

Centisome position: 41.03

GC content: 74.32

Gene sequence:

>1110_bases
GTGACGGTCTTCACGCCCACGATCCTGCTCTGTGCCGGCGGCACCGGCGGCCATCTCTTCCCCGCCGAGAGTCTCGCCCA
CGCGCTGCGGGCCCGCGGCATCCGGGTGGCCCTCGCCACCGACGCCCGGGTCGATTCCATCGCGTCCGAGTTCCCGGCCT
CCGAGGTGGTGACCATCGCGTCGGCGACGCCGTCCGGCCGCTCGCCGCTCAAGCGGGCCGGCGCCGTGCTGACCCTCGGC
CGCGGGTTCGGCGTGGCCGCGAAGGAGATCCGCCGGATCAACCCGGCGGCCATCGTTGGCTTCGGTGGCTACCCGACAGT
CCCACCGGTGCTCGCCGGCCAGATCCTGCGCGTGCCGACGATCCTGCACGAGCAGAACGCCGTGATGGGCCGGGCCAACG
CTTTCCTGGCGCGGGGCGCCCGCACCATCGCCACCGGCTTCAAGGTCGTGCGCGGCGTGCCCGACAAGGCGAGAGCCCCG
CGGATCCACACCGGCAACCCGCTCCGCCCGGCGGTGATCGAGGCGGCGAAGGTCCCGTATCCCGCTTTCGGACCGGACGA
CGCCCTGCGGCTCCTGGTGTTCGGCGGTAGCCAGGGCGCCCGCGTGATGGGCGAGGTCGTGCCCGAGGCGATCGCCCGCC
TGCCCGACGCACTGCGCGCCCGGCTGCACCTCGTCCAGCAGGTCCGCCCCGAGGACCTGACGGCGGTGCAGAACCGCTAC
CTCGCCATGGGGCTCGCCGGGATCGAGGCGGCGCCGTTCTTCAAGGACCTGCCGGCACGGATGGCCGCGAGCCACCTCGT
GGTCTCGCGCTCGGGCGCCTCGACGGTCTCGGAACTGGCGGCGATCGGCCGCCCGGCGATCCTCGTGCCGCTGCCCGGCT
CCCTCGACCAGGACCAGGCCGCCAACGCCGCGACCCTCGACGCGATCGGCGCGGCGCTGGCCGTGAAGCAGCCGGATTTC
ACGCCGGAGCGCCTCGCCGCGGAGCTGACCGCCTGCTTCGCGACGCCGGCAAAATTGACCGCGGCGGCCGATGCGGCCAG
AAGCGCGGGCATCCACGACGCCGCCGAGCGGCTGGCCGAGGTCGTCGTCGAGACGGCCGCCCGCACCTGA

Upstream 100 bases:

>100_bases
CCGGCTTCCTCGTCGCCCTGACCCGCAAGCGCCCCCGCACCGTGATGCTCAGCCAGAAGCCCCCCGGCACCGCGCCCGCC
ACCGTCGCCGGAGTGATGCG

Downstream 100 bases:

>100_bases
TCCTCAAGGGATTCCGCACCGGCGGTCCCGCCACCAGACGGTTCGACCCATGAAGCTGCCCGACAAGCTCGGCCCCATCC
ACTTCATCGGCATCGGCGGC

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTVFTPTILLCAGGTGGHLFPAESLAHALRARGIRVALATDARVDSIASEFPASEVVTIASATPSGRSPLKRAGAVLTLG
RGFGVAAKEIRRINPAAIVGFGGYPTVPPVLAGQILRVPTILHEQNAVMGRANAFLARGARTIATGFKVVRGVPDKARAP
RIHTGNPLRPAVIEAAKVPYPAFGPDDALRLLVFGGSQGARVMGEVVPEAIARLPDALRARLHLVQQVRPEDLTAVQNRY
LAMGLAGIEAAPFFKDLPARMAASHLVVSRSGASTVSELAAIGRPAILVPLPGSLDQDQAANAATLDAIGAALAVKQPDF
TPERLAAELTACFATPAKLTAAADAARSAGIHDAAERLAEVVVETAART

Sequences:

>Translated_369_residues
MTVFTPTILLCAGGTGGHLFPAESLAHALRARGIRVALATDARVDSIASEFPASEVVTIASATPSGRSPLKRAGAVLTLG
RGFGVAAKEIRRINPAAIVGFGGYPTVPPVLAGQILRVPTILHEQNAVMGRANAFLARGARTIATGFKVVRGVPDKARAP
RIHTGNPLRPAVIEAAKVPYPAFGPDDALRLLVFGGSQGARVMGEVVPEAIARLPDALRARLHLVQQVRPEDLTAVQNRY
LAMGLAGIEAAPFFKDLPARMAASHLVVSRSGASTVSELAAIGRPAILVPLPGSLDQDQAANAATLDAIGAALAVKQPDF
TPERLAAELTACFATPAKLTAAADAARSAGIHDAAERLAEVVVETAART
>Mature_368_residues
TVFTPTILLCAGGTGGHLFPAESLAHALRARGIRVALATDARVDSIASEFPASEVVTIASATPSGRSPLKRAGAVLTLGR
GFGVAAKEIRRINPAAIVGFGGYPTVPPVLAGQILRVPTILHEQNAVMGRANAFLARGARTIATGFKVVRGVPDKARAPR
IHTGNPLRPAVIEAAKVPYPAFGPDDALRLLVFGGSQGARVMGEVVPEAIARLPDALRARLHLVQQVRPEDLTAVQNRYL
AMGLAGIEAAPFFKDLPARMAASHLVVSRSGASTVSELAAIGRPAILVPLPGSLDQDQAANAATLDAIGAALAVKQPDFT
PERLAAELTACFATPAKLTAAADAARSAGIHDAAERLAEVVVETAART

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=363, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_METRJ (B1LXZ4)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001755034.1
- ProteinModelPortal:   B1LXZ4
- SMR:   B1LXZ4
- GeneID:   6138388
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2356
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   CLSK2331425
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38116; Mature: 37984

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFTPTILLCAGGTGGHLFPAESLAHALRARGIRVALATDARVDSIASEFPASEVVTIA
CCEECCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEE
SATPSGRSPLKRAGAVLTLGRGFGVAAKEIRRINPAAIVGFGGYPTVPPVLAGQILRVPT
ECCCCCCCHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHH
ILHEQNAVMGRANAFLARGARTIATGFKVVRGVPDKARAPRIHTGNPLRPAVIEAAKVPY
HHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHCCCC
PAFGPDDALRLLVFGGSQGARVMGEVVPEAIARLPDALRARLHLVQQVRPEDLTAVQNRY
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHH
LAMGLAGIEAAPFFKDLPARMAASHLVVSRSGASTVSELAAIGRPAILVPLPGSLDQDQA
HHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHC
ANAATLDAIGAALAVKQPDFTPERLAAELTACFATPAKLTAAADAARSAGIHDAAERLAE
CCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
VVVETAART
HHHHHHCCC
>Mature Secondary Structure 
TVFTPTILLCAGGTGGHLFPAESLAHALRARGIRVALATDARVDSIASEFPASEVVTIA
CEECCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCEEEEE
SATPSGRSPLKRAGAVLTLGRGFGVAAKEIRRINPAAIVGFGGYPTVPPVLAGQILRVPT
ECCCCCCCHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHH
ILHEQNAVMGRANAFLARGARTIATGFKVVRGVPDKARAPRIHTGNPLRPAVIEAAKVPY
HHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHCCCC
PAFGPDDALRLLVFGGSQGARVMGEVVPEAIARLPDALRARLHLVQQVRPEDLTAVQNRY
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHH
LAMGLAGIEAAPFFKDLPARMAASHLVVSRSGASTVSELAAIGRPAILVPLPGSLDQDQA
HHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHC
ANAATLDAIGAALAVKQPDFTPERLAAELTACFATPAKLTAAADAARSAGIHDAAERLAE
CCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
VVVETAART
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA