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The map label for this gene is srpA [H]

Identifier: 170748306

GI number: 170748306

Start: 2013708

End: 2014694

Strand: Reverse

Name: srpA [H]

Synonym: Mrad2831_1888

Alternate gene names: 170748306

Gene position: 2014694-2013708 (Counterclockwise)

Preceding gene: 170748307

Following gene: 170748303

Centisome position: 33.15

GC content: 71.73

Gene sequence:

>987_bases
ATGCCGCGTTCGAGATCGGGTTTCGCCCTCCTGCTGAGCACCGCGCTCACGGTCGCCGCCCCGGCCCTGGCCCAGGAGGC
CTCCACCGCCGAGCAGACGATCGACGTGATGAACACGCTGTTCGGGAAGCATCCCGGGGCGCGGGCCAACCACGCCAAGG
GCGTCGTCGCCGAGGGCAGCTTCACCCCGTCGCCCGAGGCGGCGAAGATCAGCAAGGCGTCCCTGTTCCGGGGGCCGGCG
GTGCCGGTGACGGTCCGGTTCTCGGACGCCACCGGCGTCCCGACCATCCCGGACGGCGCCGCCGACGCCAACCCGCACGG
CCTCGCGCTCAAGTTCAAGCTGAGCGACGGCTCCGAGATGGACGTCGTCACCAACGCGCTGAAGTACTTCCCCGTCGCCA
CGGGCGAGGAGTTCCGCGACCTCCTCAAGGCCGCCGCCGAGAGCGGCCCGACGGCCGCCCATCCGACCGCGCTGGAGCGC
TTCGCCGCCGCCCACCCGGCCGCCGCCACCGCGGGCGGAACCGCCAAGACCCCGTCGAGCCTCGCCCGGCAGACCTACAA
CGGCGTCAACGCCTTCATCCTGGTGGACGCCGCCGGCAAGCGGCAGCCGTTCCGGTTCCGCTTCGTGCCGGTGGAGGGCG
AGGAGATCCTCGCCCCCGAGGAGGCGGCCAAGCGCGATCCGAACTTCCTGATGGCCGAGATCGGCCCGCGGGTCGCCAAG
ACTCCCGCGAAGTTCAGGATGCTGGCCCAGCTCGCCGAGCCGGGCGATCCGACCAACGACGCCACCAAGCCCTGGCCGGA
CGACCGCAGGACCGTCGATCTCGGCACCGTGACGGTGAGCAAGGTCGTGCCCGACAGCGCCGAGGCCGAGAAGGCGCTGC
TGTTCATGCCCAACAACCTCACCGACGGGATCGAGGTCTCGGACGACCCGCTGATCGACGCCCGCGTCCAGGCCTACGCG
GTCTCGTTCAGCCGCCGCTCGCAGTAG

Upstream 100 bases:

>100_bases
GGCATAGCTTTTGGTTGTGCCCTCGTTGCCTGGCTCCCTAGAAGATGGGCCGGTCCGCATTGATCGGCTCCCGTGAGCCC
GCGCTGCCGAGAGGTTCCCC

Downstream 100 bases:

>100_bases
CGCGGTCCGGCCGGACGGGATTTCCGGCTCGCGTCCTCACCCTGAGGCACCCGCCTCAGGATGAGGTCGAGGGTTGGGCG
GTCGCCCGGACCGGGCGGAT

Product: catalase domain-containing protein

Products: O2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPRSRSGFALLLSTALTVAAPALAQEASTAEQTIDVMNTLFGKHPGARANHAKGVVAEGSFTPSPEAAKISKASLFRGPA
VPVTVRFSDATGVPTIPDGAADANPHGLALKFKLSDGSEMDVVTNALKYFPVATGEEFRDLLKAAAESGPTAAHPTALER
FAAAHPAAATAGGTAKTPSSLARQTYNGVNAFILVDAAGKRQPFRFRFVPVEGEEILAPEEAAKRDPNFLMAEIGPRVAK
TPAKFRMLAQLAEPGDPTNDATKPWPDDRRTVDLGTVTVSKVVPDSAEAEKALLFMPNNLTDGIEVSDDPLIDARVQAYA
VSFSRRSQ

Sequences:

>Translated_328_residues
MPRSRSGFALLLSTALTVAAPALAQEASTAEQTIDVMNTLFGKHPGARANHAKGVVAEGSFTPSPEAAKISKASLFRGPA
VPVTVRFSDATGVPTIPDGAADANPHGLALKFKLSDGSEMDVVTNALKYFPVATGEEFRDLLKAAAESGPTAAHPTALER
FAAAHPAAATAGGTAKTPSSLARQTYNGVNAFILVDAAGKRQPFRFRFVPVEGEEILAPEEAAKRDPNFLMAEIGPRVAK
TPAKFRMLAQLAEPGDPTNDATKPWPDDRRTVDLGTVTVSKVVPDSAEAEKALLFMPNNLTDGIEVSDDPLIDARVQAYA
VSFSRRSQ
>Mature_327_residues
PRSRSGFALLLSTALTVAAPALAQEASTAEQTIDVMNTLFGKHPGARANHAKGVVAEGSFTPSPEAAKISKASLFRGPAV
PVTVRFSDATGVPTIPDGAADANPHGLALKFKLSDGSEMDVVTNALKYFPVATGEEFRDLLKAAAESGPTAAHPTALERF
AAAHPAAATAGGTAKTPSSLARQTYNGVNAFILVDAAGKRQPFRFRFVPVEGEEILAPEEAAKRDPNFLMAEIGPRVAKT
PAKFRMLAQLAEPGDPTNDATKPWPDDRRTVDLGTVTVSKVVPDSAEAEKALLFMPNNLTDGIEVSDDPLIDARVQAYAV
SFSRRSQ

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Escherichia coli, GI48994891, Length=296, Percent_Identity=28.3783783783784, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321525, Length=294, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6

Molecular weight: Translated: 34544; Mature: 34413

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSRSGFALLLSTALTVAAPALAQEASTAEQTIDVMNTLFGKHPGARANHAKGVVAEGS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
FTPSPEAAKISKASLFRGPAVPVTVRFSDATGVPTIPDGAADANPHGLALKFKLSDGSEM
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCH
DVVTNALKYFPVATGEEFRDLLKAAAESGPTAAHPTALERFAAAHPAAATAGGTAKTPSS
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCHHH
LARQTYNGVNAFILVDAAGKRQPFRFRFVPVEGEEILAPEEAAKRDPNFLMAEIGPRVAK
HHHHHHCCCEEEEEEECCCCCCCEEEEEEEECCCCEECCHHHHCCCCCEEEECCCCHHHC
TPAKFRMLAQLAEPGDPTNDATKPWPDDRRTVDLGTVTVSKVVPDSAEAEKALLFMPNNL
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECEEEEEHHCCCCCCCCEEEEECCCCC
TDGIEVSDDPLIDARVQAYAVSFSRRSQ
CCCCCCCCCCCHHHHHHEEEEEHHHCCC
>Mature Secondary Structure 
PRSRSGFALLLSTALTVAAPALAQEASTAEQTIDVMNTLFGKHPGARANHAKGVVAEGS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
FTPSPEAAKISKASLFRGPAVPVTVRFSDATGVPTIPDGAADANPHGLALKFKLSDGSEM
CCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCH
DVVTNALKYFPVATGEEFRDLLKAAAESGPTAAHPTALERFAAAHPAAATAGGTAKTPSS
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCHHH
LARQTYNGVNAFILVDAAGKRQPFRFRFVPVEGEEILAPEEAAKRDPNFLMAEIGPRVAK
HHHHHHCCCEEEEEEECCCCCCCEEEEEEEECCCCEECCHHHHCCCCCEEEECCCCHHHC
TPAKFRMLAQLAEPGDPTNDATKPWPDDRRTVDLGTVTVSKVVPDSAEAEKALLFMPNNL
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECEEEEEHHCCCCCCCCEEEEECCCCC
TDGIEVSDDPLIDARVQAYAVSFSRRSQ
CCCCCCCCCCCHHHHHHEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: H2O2

Specific reaction: 2 H2O2 = O2 + 2 H2O

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]