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The map label for this gene is 170747807

Identifier: 170747807

GI number: 170747807

Start: 1449170

End: 1451068

Strand: Reverse

Name: 170747807

Synonym: Mrad2831_1389

Alternate gene names: NA

Gene position: 1451068-1449170 (Counterclockwise)

Preceding gene: 170747808

Following gene: 170747806

Centisome position: 23.87

GC content: 77.46

Gene sequence:

>1899_bases
ATGAGCCAGCAGCCCGGCAGCCTGACCCGCCAGCAGCTCTACGACCGGATCCGCGAGAGCTCGAAGGACGAGGTCATCCT
CGAGGAGATGATCCGGCTCGGCTTCTGGCCGGACGGGGAAGCGCAGCCCAACCCGCCGGACGACCTGATCCGCCGCCGCG
GCGAGATCGCCCGCGCCCTCGCCGACCTCCACCGGCGGGAGGCGGCGTGGCGCGACCCCGAGGCCGCCCTCAAGGAGATG
CATCGCCGCCGCAAGACGGCGGCGCTGGAGCGGCGGCGCGAGACGAGGCTGCGCAACGCCCGCGACCGCCACGCCCGGGC
GCAGGCGTGGCACGCGCGCCGGGAGGCCGAGATCCTCCATCTCGGGGACGGCGTCTCGGCCGGACTCTCGGCCGGGCTCG
CGCACGCGGCTCCGGACGCGGGCACGCCCGCGCGCGGGCCCGCCCCCGGGCTCCCGCCCCTGGCGAGCCCGAAGGCGCTG
GCCGAGGCCATGGGGATCGGCCTCGGCGAGCTGCGCTTCCTCGCCTACGACCGGGCGCTCAGCACGGTGAGCCATTACCG
GCGCTTCACCATCCCCAAGAAGGCGGGCGGGCTGCGCCGCATCTCGGCGCCGATGCCGCGCCTGAAGCGGGCGCAGTACT
GGATCCTCGACGCGCTCCTCGCCCACGCCCCCGTGCACCCGGCGGCCCACGGCTTCGTGCCGGGCCGCTCGATCGTCACC
AACGCCGCCGCCCATGTCGGGCGGGACGTCGTGGTCAATCTCGACCTCAAGGACTTCTTCCCGAGCCTCGACTATCGGCG
GATCAAGGGGAAGTTCCGGGGCCTGGGCTACGCCGAGCCGGTGGCGACCGTGCTGGCGCTGCTGTGCACCGAGCCGGACG
TGGACGCGGTCGAGATCGACGGCGCCCGCCTCTACGCCGCCCGGGGGCCCCGCCGGCTGCCGCAGGGCGCGCCGACGAGC
CCCGCGCTCACCAACCTCGTCTGCACCCGGCTCGACGCCCGGCTCTCCGGGCTCGCCGGCAGCCTCGGCTTCACCTACAC
GCGCTACGCCGACGACCTGACCTTCTCGGCCTCGGGCGAGGCCGCCGGGAAGGTCGGCGCGCTGCTCAAGTACGTCCACG
CCATCGTCGCCGGGGAGGGCTTCACCGTCCATCCGGACAAGACCCGGGTGATGCGCCGCGGCCGGCACCAGGAGGTGACC
GGGCTGACCGTCAACGAGCGGGTCGGCGTGCCCCGCGAGACCCTGCGCCGCTTCCGCGCCCTCCTGCACGGGCTCGAGCG
GCACGGACCGGTCGGGCGCCGCTGGGGCGCGGCCGGCGAGGCGGGCGTGCTCCGCGCCGCCGTCGGCTTCGCGCAGTTCG
TCCGGATGGTCACGCCGGAGACCGGCGCGCCGCTGCTGGCGCGGGCCCGCGCCCTCGCGGACCGCCACGCGGACCGCCCC
TCGGCCCGTCCGGGGGCCCGGCCGCTGCCGGATTTCCGCGCCCGGTCCGCCCGGGGCGAGGTGCCGCTCGCCCGCTGGTG
GGCGCCCGCCCCCCGCCCCGCGCCCGAGCCGGACCCGATCCTGGCCGAGGCCGAGGCGGCCGCCGCGCGGGAGGCGGAGG
AGGCCGCGGCCAGGGCTGCGGCCCGCGCGGCCGCGCCGGTGCCGGGCCGCAGCGGCGTCCCGGTCTCCGGGCGCCCGCGT
CTCGGCGCGCCGGAACCGACCGCCCGCGCGGAGGTCGCCCCGGACACGGGCGCGGAGCCCGACGACGCCCCGATGAAGCC
CTGGAAGGTCATCCTGGGGATCTTCGTCCTGTTCCAGGCCGCCGCCCTGCTGCACCCGGCGCTCGGGCTGCTCGTCCTCG
CGGTCGCCCTGCTGCTCGGTCTCCGACGCCTGCTGCGCCGCTGGCGACGGCGCCGATGA

Upstream 100 bases:

>100_bases
TCGTGCCGGCGTCGAGTGGACCGGGCCAGTCCCGAGACTTGACGAAGGCATCCCGGCCGACGTCCCCCGTCACGCCTCCT
GCCCGCGCCGGAGGTTGCCG

Downstream 100 bases:

>100_bases
GGCTCGCCCGGCGCCTCCCGGCCGGGCACCTCCGGACCAGCCTCGCCGCGCTCTTCGCCCTGGCCCCGGTCCTCTCGCTC
GGACCGGGGGCGTCCCGGGC

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Mx162-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MSQQPGSLTRQQLYDRIRESSKDEVILEEMIRLGFWPDGEAQPNPPDDLIRRRGEIARALADLHRREAAWRDPEAALKEM
HRRRKTAALERRRETRLRNARDRHARAQAWHARREAEILHLGDGVSAGLSAGLAHAAPDAGTPARGPAPGLPPLASPKAL
AEAMGIGLGELRFLAYDRALSTVSHYRRFTIPKKAGGLRRISAPMPRLKRAQYWILDALLAHAPVHPAAHGFVPGRSIVT
NAAAHVGRDVVVNLDLKDFFPSLDYRRIKGKFRGLGYAEPVATVLALLCTEPDVDAVEIDGARLYAARGPRRLPQGAPTS
PALTNLVCTRLDARLSGLAGSLGFTYTRYADDLTFSASGEAAGKVGALLKYVHAIVAGEGFTVHPDKTRVMRRGRHQEVT
GLTVNERVGVPRETLRRFRALLHGLERHGPVGRRWGAAGEAGVLRAAVGFAQFVRMVTPETGAPLLARARALADRHADRP
SARPGARPLPDFRARSARGEVPLARWWAPAPRPAPEPDPILAEAEAAAAREAEEAAARAAARAAAPVPGRSGVPVSGRPR
LGAPEPTARAEVAPDTGAEPDDAPMKPWKVILGIFVLFQAAALLHPALGLLVLAVALLLGLRRLLRRWRRRR

Sequences:

>Translated_632_residues
MSQQPGSLTRQQLYDRIRESSKDEVILEEMIRLGFWPDGEAQPNPPDDLIRRRGEIARALADLHRREAAWRDPEAALKEM
HRRRKTAALERRRETRLRNARDRHARAQAWHARREAEILHLGDGVSAGLSAGLAHAAPDAGTPARGPAPGLPPLASPKAL
AEAMGIGLGELRFLAYDRALSTVSHYRRFTIPKKAGGLRRISAPMPRLKRAQYWILDALLAHAPVHPAAHGFVPGRSIVT
NAAAHVGRDVVVNLDLKDFFPSLDYRRIKGKFRGLGYAEPVATVLALLCTEPDVDAVEIDGARLYAARGPRRLPQGAPTS
PALTNLVCTRLDARLSGLAGSLGFTYTRYADDLTFSASGEAAGKVGALLKYVHAIVAGEGFTVHPDKTRVMRRGRHQEVT
GLTVNERVGVPRETLRRFRALLHGLERHGPVGRRWGAAGEAGVLRAAVGFAQFVRMVTPETGAPLLARARALADRHADRP
SARPGARPLPDFRARSARGEVPLARWWAPAPRPAPEPDPILAEAEAAAAREAEEAAARAAARAAAPVPGRSGVPVSGRPR
LGAPEPTARAEVAPDTGAEPDDAPMKPWKVILGIFVLFQAAALLHPALGLLVLAVALLLGLRRLLRRWRRRR
>Mature_631_residues
SQQPGSLTRQQLYDRIRESSKDEVILEEMIRLGFWPDGEAQPNPPDDLIRRRGEIARALADLHRREAAWRDPEAALKEMH
RRRKTAALERRRETRLRNARDRHARAQAWHARREAEILHLGDGVSAGLSAGLAHAAPDAGTPARGPAPGLPPLASPKALA
EAMGIGLGELRFLAYDRALSTVSHYRRFTIPKKAGGLRRISAPMPRLKRAQYWILDALLAHAPVHPAAHGFVPGRSIVTN
AAAHVGRDVVVNLDLKDFFPSLDYRRIKGKFRGLGYAEPVATVLALLCTEPDVDAVEIDGARLYAARGPRRLPQGAPTSP
ALTNLVCTRLDARLSGLAGSLGFTYTRYADDLTFSASGEAAGKVGALLKYVHAIVAGEGFTVHPDKTRVMRRGRHQEVTG
LTVNERVGVPRETLRRFRALLHGLERHGPVGRRWGAAGEAGVLRAAVGFAQFVRMVTPETGAPLLARARALADRHADRPS
ARPGARPLPDFRARSARGEVPLARWWAPAPRPAPEPDPILAEAEAAAAREAEEAAARAAARAAAPVPGRSGVPVSGRPRL
GAPEPTARAEVAPDTGAEPDDAPMKPWKVILGIFVLFQAAALLHPALGLLVLAVALLLGLRRLLRRWRRRR

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 68684; Mature: 68553

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQPGSLTRQQLYDRIRESSKDEVILEEMIRLGFWPDGEAQPNPPDDLIRRRGEIARAL
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADLHRREAAWRDPEAALKEMHRRRKTAALERRRETRLRNARDRHARAQAWHARREAEILH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LGDGVSAGLSAGLAHAAPDAGTPARGPAPGLPPLASPKALAEAMGIGLGELRFLAYDRAL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
STVSHYRRFTIPKKAGGLRRISAPMPRLKRAQYWILDALLAHAPVHPAAHGFVPGRSIVT
HHHHHHHHHCCCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
NAAAHVGRDVVVNLDLKDFFPSLDYRRIKGKFRGLGYAEPVATVLALLCTEPDVDAVEID
HHHHHCCCCEEEECCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEC
GARLYAARGPRRLPQGAPTSPALTNLVCTRLDARLSGLAGSLGFTYTRYADDLTFSASGE
CCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCC
AAGKVGALLKYVHAIVAGEGFTVHPDKTRVMRRGRHQEVTGLTVNERVGVPRETLRRFRA
HHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHH
LLHGLERHGPVGRRWGAAGEAGVLRAAVGFAQFVRMVTPETGAPLLARARALADRHADRP
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SARPGARPLPDFRARSARGEVPLARWWAPAPRPAPEPDPILAEAEAAAAREAEEAAARAA
CCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ARAAAPVPGRSGVPVSGRPRLGAPEPTARAEVAPDTGAEPDDAPMKPWKVILGIFVLFQA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AALLHPALGLLVLAVALLLGLRRLLRRWRRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQQPGSLTRQQLYDRIRESSKDEVILEEMIRLGFWPDGEAQPNPPDDLIRRRGEIARAL
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
ADLHRREAAWRDPEAALKEMHRRRKTAALERRRETRLRNARDRHARAQAWHARREAEILH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LGDGVSAGLSAGLAHAAPDAGTPARGPAPGLPPLASPKALAEAMGIGLGELRFLAYDRAL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
STVSHYRRFTIPKKAGGLRRISAPMPRLKRAQYWILDALLAHAPVHPAAHGFVPGRSIVT
HHHHHHHHHCCCHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
NAAAHVGRDVVVNLDLKDFFPSLDYRRIKGKFRGLGYAEPVATVLALLCTEPDVDAVEID
HHHHHCCCCEEEECCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEC
GARLYAARGPRRLPQGAPTSPALTNLVCTRLDARLSGLAGSLGFTYTRYADDLTFSASGE
CCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCC
AAGKVGALLKYVHAIVAGEGFTVHPDKTRVMRRGRHQEVTGLTVNERVGVPRETLRRFRA
HHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHH
LLHGLERHGPVGRRWGAAGEAGVLRAAVGFAQFVRMVTPETGAPLLARARALADRHADRP
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SARPGARPLPDFRARSARGEVPLARWWAPAPRPAPEPDPILAEAEAAAAREAEEAAARAA
CCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ARAAAPVPGRSGVPVSGRPRLGAPEPTARAEVAPDTGAEPDDAPMKPWKVILGIFVLFQA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AALLHPALGLLVLAVALLLGLRRLLRRWRRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2465092; 2465091 [H]