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The map label for this gene is 170747247

Identifier: 170747247

GI number: 170747247

Start: 857751

End: 859049

Strand: Reverse

Name: 170747247

Synonym: Mrad2831_0814

Alternate gene names: NA

Gene position: 859049-857751 (Counterclockwise)

Preceding gene: 170747248

Following gene: 170747245

Centisome position: 14.13

GC content: 77.75

Gene sequence:

>1299_bases
TTGGACCGGAGCGAAACCCTCGCCGCCCTGCGGCGCGGCGAACTCGGCGGCGCGCGGGAGCTGCGGCTGCCCGACGGGCT
GACGGCGGTGCCGCGCGAGGTCTTCGCCCTCGCCGACACGCTGGAGGTGCTGGATCTCGGCCGGGGCAGCCTCGTCGACC
TGCCGGACGATTTCGGCCGCCTCCACCGCCTGCGCGTCCTGTTCTGCTCCGGCAACCCGTTCCCGCGCCTGCCGCCGGTG
CTCGGCGCCTGCCCGGCGCTGAGCCAGCTGGGCTTCCGCGGCTGCGGCATCCGCGAGGTTCCGGCGGAGTCGCTGCCGCG
CGAGCTGCGCTGGCTGACGCTGACCGACAACGCGATCGCCGAGCTGCCCGCCGCCCTCGGCGAGCGGCCGCGCCTGCGGA
AGCTGATGCTGGCGGGCAATCGGCTCAGCGCGCTGCCCGACAGCCTGTCGGGGGCGGACGAACTCGAGCTGATCCGAGTC
GCCTGCAACCGTCTCGTGGCGCTCCCGCCGTGGCTCGCGCGCCTGCCCCGCCTCGCCTGGATCGCCTACGCCGGCAACCC
CGCCGAGCCGCCGACGGCGCCGGTGGCAGCGCCCGCGGTGCTGTGGGCCGACCTCGCCCTCGGCGAGCTGCTCGGCGAGG
GCGCCTCGGGGCGGGTCCACCGGGCCCGCTGGCGGGGGCCGGCCGGCGGGGAGGACGTGGCCCTGAAGCTGTTCAAGGGC
GCGATGACCAGCGACGGCCTGCCCGAGCGGGAGATGGAGGCCTGCCTCGCCGCCGGGATGCACCCGGCCCTCACGGGCGC
GCTCGGCCGGCTCGACGGCCATCCCGACGGCGCGACGGGACTGCTGCTCCGGCTCCTGCCGGCGCACTGGCGCCCGCTCG
CCGGGCCGCCGAGCCTCGCGAGCTGCAGCCGCGACGTCTACGACCCGGACCTGCGCCTCGACGGCGACGCGGCCCTGCGG
ATCGCCCGCGCCGTGGCCGAGGCGGTGGCGCACCTGCACGGGCGGGGCCTGCTGCACGGCGACGTCTACGCCCACAACAC
GCTCTGGGACGCCGGAACCGGCGCGGCCGTGCTCAGCGATTTCGGGGCGGCCTCGGCCCTGCCGGACGGGCCGCTCGGCG
CGGCTCGGGCGCGGGTCGAGGTCCGCGCCGTCGGCATCCTGATCGGCGAGCTGCTCGACCGCTGCGCGGCGCCGCCGGAA
ACCCTGCGCGCCCTGGCGCAGGCGTGCACGGGGCCGGATGTCGACGGGCGGCCGGACCTCGGGGCGGTGATCGCCGAGAT
CGGGCGGCTCCAGGCCTGA

Upstream 100 bases:

>100_bases
CGCGCTCCTGCGCGCCGAGATCGCCCGGCTCGAGGCGGCGCGGGCCGCCAAGCAGGCGGCGCAGGGCGCGGCCGACGCCT
TCTTCAAGCGGGGCTGAGGC

Downstream 100 bases:

>100_bases
GCGCGGCGTCGACCGGTCCCGGGACCCTTCCGCCGCCCTCGCCGCGGCTCAGTCCGGGATGTCGCCCTGCCCGCGCGCGA
CCACCGCGAACAGGTCGCCG

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: Protein Kinase; Leucine-Rich Repeat-Containing Protein Kinase; Leucine-Rich Repeat Protein; Kinase; Serine/Threonine-Protein Kinase-Like Domain Protein; Serine/Threonine-Protein Kinase-Like Domain; Cytoplasmic Membrane Protein; Leucine-Rich Repeat-Containing Protein; Protein Kinase Domain-Containing Protein; Protein KinaseLeucine-Rich Repeat Protein

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MDRSETLAALRRGELGGARELRLPDGLTAVPREVFALADTLEVLDLGRGSLVDLPDDFGRLHRLRVLFCSGNPFPRLPPV
LGACPALSQLGFRGCGIREVPAESLPRELRWLTLTDNAIAELPAALGERPRLRKLMLAGNRLSALPDSLSGADELELIRV
ACNRLVALPPWLARLPRLAWIAYAGNPAEPPTAPVAAPAVLWADLALGELLGEGASGRVHRARWRGPAGGEDVALKLFKG
AMTSDGLPEREMEACLAAGMHPALTGALGRLDGHPDGATGLLLRLLPAHWRPLAGPPSLASCSRDVYDPDLRLDGDAALR
IARAVAEAVAHLHGRGLLHGDVYAHNTLWDAGTGAAVLSDFGAASALPDGPLGAARARVEVRAVGILIGELLDRCAAPPE
TLRALAQACTGPDVDGRPDLGAVIAEIGRLQA

Sequences:

>Translated_432_residues
MDRSETLAALRRGELGGARELRLPDGLTAVPREVFALADTLEVLDLGRGSLVDLPDDFGRLHRLRVLFCSGNPFPRLPPV
LGACPALSQLGFRGCGIREVPAESLPRELRWLTLTDNAIAELPAALGERPRLRKLMLAGNRLSALPDSLSGADELELIRV
ACNRLVALPPWLARLPRLAWIAYAGNPAEPPTAPVAAPAVLWADLALGELLGEGASGRVHRARWRGPAGGEDVALKLFKG
AMTSDGLPEREMEACLAAGMHPALTGALGRLDGHPDGATGLLLRLLPAHWRPLAGPPSLASCSRDVYDPDLRLDGDAALR
IARAVAEAVAHLHGRGLLHGDVYAHNTLWDAGTGAAVLSDFGAASALPDGPLGAARARVEVRAVGILIGELLDRCAAPPE
TLRALAQACTGPDVDGRPDLGAVIAEIGRLQA
>Mature_432_residues
MDRSETLAALRRGELGGARELRLPDGLTAVPREVFALADTLEVLDLGRGSLVDLPDDFGRLHRLRVLFCSGNPFPRLPPV
LGACPALSQLGFRGCGIREVPAESLPRELRWLTLTDNAIAELPAALGERPRLRKLMLAGNRLSALPDSLSGADELELIRV
ACNRLVALPPWLARLPRLAWIAYAGNPAEPPTAPVAAPAVLWADLALGELLGEGASGRVHRARWRGPAGGEDVALKLFKG
AMTSDGLPEREMEACLAAGMHPALTGALGRLDGHPDGATGLLLRLLPAHWRPLAGPPSLASCSRDVYDPDLRLDGDAALR
IARAVAEAVAHLHGRGLLHGDVYAHNTLWDAGTGAAVLSDFGAASALPDGPLGAARARVEVRAVGILIGELLDRCAAPPE
TLRALAQACTGPDVDGRPDLGAVIAEIGRLQA

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI238908508, Length=233, Percent_Identity=26.6094420600858, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI157743290, Length=162, Percent_Identity=32.7160493827161, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI122937315, Length=225, Percent_Identity=29.7777777777778, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI110825984, Length=163, Percent_Identity=32.5153374233129, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI95113664, Length=186, Percent_Identity=30.6451612903226, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI45827731, Length=171, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI45827729, Length=170, Percent_Identity=31.1764705882353, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71991531, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71991525, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71993783, Length=203, Percent_Identity=30.5418719211823, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71993778, Length=203, Percent_Identity=30.5418719211823, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24650334, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650332, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650330, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362653, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362657, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472958, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650336, Length=199, Percent_Identity=31.1557788944724, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362651, Length=207, Percent_Identity=30.9178743961353, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007092, Length=207, Percent_Identity=30.9178743961353, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281362655, Length=207, Percent_Identity=30.9178743961353, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45423; Mature: 45423

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRSETLAALRRGELGGARELRLPDGLTAVPREVFALADTLEVLDLGRGSLVDLPDDFGR
CCHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHH
LHRLRVLFCSGNPFPRLPPVLGACPALSQLGFRGCGIREVPAESLPRELRWLTLTDNAIA
HEEEEEEEECCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCHHHCCHHCEEEEECCHHHH
ELPAALGERPRLRKLMLAGNRLSALPDSLSGADELELIRVACNRLVALPPWLARLPRLAW
HHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHEE
IAYAGNPAEPPTAPVAAPAVLWADLALGELLGEGASGRVHRARWRGPAGGEDVALKLFKG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHH
AMTSDGLPEREMEACLAAGMHPALTGALGRLDGHPDGATGLLLRLLPAHWRPLAGPPSLA
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
SCSRDVYDPDLRLDGDAALRIARAVAEAVAHLHGRGLLHGDVYAHNTLWDAGTGAAVLSD
HHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCCCCCHHHHHH
FGAASALPDGPLGAARARVEVRAVGILIGELLDRCAAPPETLRALAQACTGPDVDGRPDL
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
GAVIAEIGRLQA
HHHHHHHHHCCC
>Mature Secondary Structure
MDRSETLAALRRGELGGARELRLPDGLTAVPREVFALADTLEVLDLGRGSLVDLPDDFGR
CCHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHH
LHRLRVLFCSGNPFPRLPPVLGACPALSQLGFRGCGIREVPAESLPRELRWLTLTDNAIA
HEEEEEEEECCCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCHHHCCHHCEEEEECCHHHH
ELPAALGERPRLRKLMLAGNRLSALPDSLSGADELELIRVACNRLVALPPWLARLPRLAW
HHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHEE
IAYAGNPAEPPTAPVAAPAVLWADLALGELLGEGASGRVHRARWRGPAGGEDVALKLFKG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHH
AMTSDGLPEREMEACLAAGMHPALTGALGRLDGHPDGATGLLLRLLPAHWRPLAGPPSLA
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
SCSRDVYDPDLRLDGDAALRIARAVAEAVAHLHGRGLLHGDVYAHNTLWDAGTGAAVLSD
HHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEECCEEECCCCCCCCCCHHHHHH
FGAASALPDGPLGAARARVEVRAVGILIGELLDRCAAPPETLRALAQACTGPDVDGRPDL
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
GAVIAEIGRLQA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA