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The map label for this gene is 170747244

Identifier: 170747244

GI number: 170747244

Start: 854990

End: 855892

Strand: Reverse

Name: 170747244

Synonym: Mrad2831_0811

Alternate gene names: NA

Gene position: 855892-854990 (Counterclockwise)

Preceding gene: 170747245

Following gene: 170747243

Centisome position: 14.08

GC content: 71.98

Gene sequence:

>903_bases
ATGACACGTCTCCTCACCGCGCTCGCTAGCCTCCTCTGCCTCGGGCTCGCCGCGTTCGGCTTCACCGCTGCCTCGCCGCT
CGCGCTGTTCGACGCGATCGGCCCGCGCGATCCGGGAGGGCGGCTCGCCGCGAAGGACCAGCCCTTCGGCGAGGGCCCGC
GGCGGCGGCTCGACGTCTACGTACCCACCGCGGGCGCCGAGAACGCGCCGGTCCTGGTGTTCTTCTACGGCGGCTCCTGG
CAGAGCGGCGCCAAGGACGACTACGCCTTCGTCGGGCACGCCCTCGCGGCGCAGGGCTTCGTCACGGTGCTGCCAGATTA
CCGGCTCTACCCGGAGGCGCCGTTCCCCGGTTTCCTCGAGGATGGCGCCGAGGCCATCGCGTGGGTGCGCGACAACATCG
CCGGATACGGCGGCGACCCGCGCCGCATCGTGCTCGCCGGCCACTCGGCGGGCGCCTACAACGCCGTGATGCTCGGCCTC
GACCCGCGCTACGTGATCGCCGCCGGGGTCGATCCCAAGGTGATCAAGGCCGTCGCCGGCCTGTCCGGCCCCTACGATTT
CCTGCCGTTCGATCAGGACACCACCGTCAAGGTGTTCGGCAAGGCCCCCGACCCGGAGGCCACGCAGCCCGTCGCCTTCG
CGGGCCCGCTCTCGCCCCCCGCCTTCCTGGCGACCGGCGACGCCGACACCGTGGTGAAGCCGCGGCACACGGTCAGCCTC
GCCGCCAAGCTGCGGGCGGAGCACGTTCCGGTCCAAGAGCGGCTCTACCCGGGCCTCGACCACAAGGACACGCTGCTGGC
GCTGTCCGTCACCTTCCGCTCGAAGGCGCCGGAACTCGCCGAGATGGCGTCCTTCCTGATGCGGCAATCCGCCGGGCGCT
CGCAGTACACGATGCGGCGGTGA

Upstream 100 bases:

>100_bases
TCGTGCTGCGGACCTGATTTTTCGTGATCCGCCCCGAGACCGTCATCAATCCGCCCCGAGGGCGGTGCGGTATGGCCCGG
TCGGGACAACCGGATGGGAT

Downstream 100 bases:

>100_bases
TCGCCCCGGGCCCGCGTCAAGGTTATCGGGCGATCGTCGGCCGCAACCGTCCGATTTCCCGTCGCCCGGCACCCGCGGCC
CGCTAGAATGATCCTGGCCG

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTRLLTALASLLCLGLAAFGFTAASPLALFDAIGPRDPGGRLAAKDQPFGEGPRRRLDVYVPTAGAENAPVLVFFYGGSW
QSGAKDDYAFVGHALAAQGFVTVLPDYRLYPEAPFPGFLEDGAEAIAWVRDNIAGYGGDPRRIVLAGHSAGAYNAVMLGL
DPRYVIAAGVDPKVIKAVAGLSGPYDFLPFDQDTTVKVFGKAPDPEATQPVAFAGPLSPPAFLATGDADTVVKPRHTVSL
AAKLRAEHVPVQERLYPGLDHKDTLLALSVTFRSKAPELAEMASFLMRQSAGRSQYTMRR

Sequences:

>Translated_300_residues
MTRLLTALASLLCLGLAAFGFTAASPLALFDAIGPRDPGGRLAAKDQPFGEGPRRRLDVYVPTAGAENAPVLVFFYGGSW
QSGAKDDYAFVGHALAAQGFVTVLPDYRLYPEAPFPGFLEDGAEAIAWVRDNIAGYGGDPRRIVLAGHSAGAYNAVMLGL
DPRYVIAAGVDPKVIKAVAGLSGPYDFLPFDQDTTVKVFGKAPDPEATQPVAFAGPLSPPAFLATGDADTVVKPRHTVSL
AAKLRAEHVPVQERLYPGLDHKDTLLALSVTFRSKAPELAEMASFLMRQSAGRSQYTMRR
>Mature_299_residues
TRLLTALASLLCLGLAAFGFTAASPLALFDAIGPRDPGGRLAAKDQPFGEGPRRRLDVYVPTAGAENAPVLVFFYGGSWQ
SGAKDDYAFVGHALAAQGFVTVLPDYRLYPEAPFPGFLEDGAEAIAWVRDNIAGYGGDPRRIVLAGHSAGAYNAVMLGLD
PRYVIAAGVDPKVIKAVAGLSGPYDFLPFDQDTTVKVFGKAPDPEATQPVAFAGPLSPPAFLATGDADTVVKPRHTVSLA
AKLRAEHVPVQERLYPGLDHKDTLLALSVTFRSKAPELAEMASFLMRQSAGRSQYTMRR

Specific function: Unknown

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-B carboxylesterase/lipase family [H]

Homologues:

Organism=Homo sapiens, GI224465228, Length=143, Percent_Identity=34.2657342657343, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI192807282, Length=143, Percent_Identity=34.2657342657343, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557351, Length=117, Percent_Identity=35.042735042735, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI310117651, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310117649, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI148536848, Length=137, Percent_Identity=32.8467153284672, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639611, Length=159, Percent_Identity=32.7044025157233, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737825, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002018
- InterPro:   IPR019826 [H]

Pfam domain/function: PF00135 COesterase [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 31919; Mature: 31788

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLLTALASLLCLGLAAFGFTAASPLALFDAIGPRDPGGRLAAKDQPFGEGPRRRLDVY
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEE
VPTAGAENAPVLVFFYGGSWQSGAKDDYAFVGHALAAQGFVTVLPDYRLYPEAPFPGFLE
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCCEECCCCCCCCHHH
DGAEAIAWVRDNIAGYGGDPRRIVLAGHSAGAYNAVMLGLDPRYVIAAGVDPKVIKAVAG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHC
LSGPYDFLPFDQDTTVKVFGKAPDPEATQPVAFAGPLSPPAFLATGDADTVVKPRHTVSL
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCCCCEECCCHHHHH
AAKLRAEHVPVQERLYPGLDHKDTLLALSVTFRSKAPELAEMASFLMRQSAGRSQYTMRR
HHHHHHHCCCHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRLLTALASLLCLGLAAFGFTAASPLALFDAIGPRDPGGRLAAKDQPFGEGPRRRLDVY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEE
VPTAGAENAPVLVFFYGGSWQSGAKDDYAFVGHALAAQGFVTVLPDYRLYPEAPFPGFLE
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCCEECCCCCCCCHHH
DGAEAIAWVRDNIAGYGGDPRRIVLAGHSAGAYNAVMLGLDPRYVIAAGVDPKVIKAVAG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHC
LSGPYDFLPFDQDTTVKVFGKAPDPEATQPVAFAGPLSPPAFLATGDADTVVKPRHTVSL
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCCCCEECCCHHHHH
AAKLRAEHVPVQERLYPGLDHKDTLLALSVTFRSKAPELAEMASFLMRQSAGRSQYTMRR
HHHHHHHCCCHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA