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The map label for this gene is pepN [H]

Identifier: 170683651

GI number: 170683651

Start: 2194212

End: 2196824

Strand: Reverse

Name: pepN [H]

Synonym: EcSMS35_2187

Alternate gene names: 170683651

Gene position: 2196824-2194212 (Counterclockwise)

Preceding gene: 170684174

Following gene: 170679821

Centisome position: 43.34

GC content: 54.5

Gene sequence:

>2613_bases
ATGACTCAACAGCCACAAGCCAAATACCGTCACGATTATCGTGCGCCGGATTACCAGATTACTGATATTGACTTGACCTT
TGACCTGGACGCGCAAAAGACGGTCGTTACCGCGGTCAGCCAGGCTGTCCGTCATGGTGCATCAGATGCTCCGCTTCGTC
TTGATGGCGAAGATCTTAAACTGGTTTCTGTTCATATTAATGATGAGCCGTGGACCGCCTGGAAAGAAGAAGAGGGCGCA
CTGGTCATCAGTAATTTGCCGGAGCGTTTTACGCTTAAGATCGTTAATGAAATTAGCCCGGCGACGAATACCGCGCTGGA
AGGGCTTTATCAGTCAGGCGATGCGCTTTGCACCCAGTGTGAAGCCGAAGGTTTCCGCCATATTACGTATTATCTCGACC
GCCCGGACGTGCTGGCGCGTTTTACCACCAAAATTATTGCCGATAAAACCCAATATCCCTTCCTGCTTTCCAACGGTAAC
CGCGTTGCGCAAGGCGAACTGGAAAACGGACGTCACTGGGTACAGTGGCAGGACCCGTTCCCTAAACCGTGCTACCTGTT
TGCGCTGGTGGCAGGCGACTTCGACGTGCTGCGCGACACCTTCACCACGCGTTCTGGTCGCGAAGTTGCGCTGGAGCTGT
ACGTCGATCGCGGCAACCTTGATCGTGCGCCGTGGGCGATGACCTCGCTGAAAAACTCCATGAAATGGGATGAAGAGCGC
TTCGGCCTGGAGTATGACCTCGACATCTATATGATCGTCGCGGTGGATTTCTTCAATATGGGCGCAATGGAGAATAAGGG
TCTGAATATCTTTAACTCCAAATATGTGCTGGCCCGCACCGATACCGCCACCGACAAAGATTACCTCGATATTGAACGCG
TTATCGGCCATGAATATTTCCATAACTGGACCGGTAACCGAGTGACCTGCCGCGACTGGTTCCAGCTCAGCCTGAAAGAA
GGTTTAACCGTCTTCCGCGATCAGGAGTTCAGCTCTGACCTTGGTTCTCGCGCGGTAAACCGTATCAACAACGTGCGCAC
CATGCGCGGATTGCAGTTTGCGGAAGACGCCAGCCCGATGGCGCACCCGATCCGCCCGGATATGGTCATTGAGATGAACA
ACTTCTACACCCTGACCGTTTACGAGAAGGGCGCGGAAGTCATTCGCATGATCCACACCCTGCTGGGCGAAGAAAACTTC
CAGAAAGGGATGCAGCTCTATTTCGAGCGCCATGATGGCAGCGCGGCAACCTGCGACGACTTTGTTCAGGCGATGGAAGA
TGCGTCGAATGTCGATCTCTCTCATTTCCGCCGTTGGTACAGCCAGTCCGGTACGCCGGTTGTGACCGTCAAAGACGACT
ATAATCCGGAAACCGAGCAGTACACCCTGACCATCAGCCAGCGTACGCCTGCTACGCCGGATCAGGCAGAAAAACAGCCG
CTGCATATTCCGTTTGCCATCGAACTGTATGACAACGAAGGCAAAGTGATCCCGTTGCAAAAAGGCGGTCATCCGGTGAA
TTCGGTGCTGAACGTCACCCAGGCGGAACAGACCTTTGTCTTTGATAATGTCTACTTTCAGCCGGTGCCTGCGCTGCTGT
GCGAATTCTCTGCGCCAGTGAAACTGGAATATAAGTGGAGCGATCAGCAACTGACCTTCCTGATGCGCCATGCGCGTAAT
GATTTCTCCCGCTGGGATGCGGCGCAAAGCCTGCTGGCAACCTACATCAAGCTAAACGTCGCCCGTCATCAGCAAGGGCA
GCCGCTGTCTCTGCCGGTGCATGTGGCTGACGCTTTCCGCGCGGTGCTGCTCGATGAGAAGATTGATCCGGCGCTGGCGG
CAGAAATCCTGACGCTGCCTTCTGTCAATGAAATGGCTGAACTGTTCGATATCATCGACCCGATTGCTATTGCCGAAGTA
CGCGAAGCACTCACTCGTACTCTGGCGACTGAACTGGCGGATGAGCTGCTGGCTATTTACAACGCGAATTACCAGAGCGA
GTACCGTGTTGAGCATGAAGATATTGCGAAACGCACTCTGCGTAATGCCTGCCTGCGCTTCCTTGCTTTTGGTGAAACGC
ATCTGGCTGACGTGCTGGTGAGCAAGCAGTTCCACGAAGCGAACAATATGACCGATGCGCTGGCGGCGCTTTCTGCGGCG
GTTGCCGCACAACTGCCATGCCGTGATGCGCTGATGCAGGAATACGACGATAAGTGGCATCTGGACGGTCTGGTGATGGA
TAAATGGTTTATCCTGCAAGCCACCAGCCCGGCGGCGAATGTGCTGGAGACGGTGCGCGGTCTGTTGCAGCATCGCTCAT
TTACCATGAGCAACCCGAACCGCATTCGTTCGTTGATTGGCGCGTTTGCGGGCAGCAACCCGGCAGCGTTCCATGCCGAA
GATGGCAGCGGTTATCAGTTCCTTGTGGAAATGCTTACCGACCTCAACAGCCGTAACCCGCAGGTGGCATCGCGCCTGAT
TGAGCCGCTGATTCGCCTGAAACGTTACGATGCCAAACGTCAGGAGAAAATGCGCGCGGCGCTGGAGCAGTTGAAAGGGC
TGGAAAATCTCTCTGGCGATCTGTACGAGAAGATCACCAAAGCACTGGCTTGA

Upstream 100 bases:

>100_bases
AGGCGTTTGTACCTGAAAAGATGAAGATTCTGCATAGCGCGATTTACGCAACAGGAATAGACTGAACACCAGACTCTATA
AAAGATGCTAAAGGTTATTT

Downstream 100 bases:

>100_bases
TAAATAACCGAATGGCGGCAATAGCGCCGCCATTCGGGGAATTTACCCCTGTTTTCTCAGGCGAATTTCAGATTCACCAC
GCTGCATCACCCTTTGCAAC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 870; Mature: 869

Protein sequence:

>870_residues
MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLDGEDLKLVSVHINDEPWTAWKEEEGA
LVISNLPERFTLKIVNEISPATNTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGN
RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEER
FGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENF
QKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQP
LHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARN
DFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEV
REALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAA
VAAQLPCRDALMQEYDDKWHLDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAE
DGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA

Sequences:

>Translated_870_residues
MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLDGEDLKLVSVHINDEPWTAWKEEEGA
LVISNLPERFTLKIVNEISPATNTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGN
RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEER
FGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENF
QKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQP
LHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARN
DFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEV
REALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAA
VAAQLPCRDALMQEYDDKWHLDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAE
DGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA
>Mature_869_residues
TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLDGEDLKLVSVHINDEPWTAWKEEEGAL
VISNLPERFTLKIVNEISPATNTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGNR
VAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERF
GLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEG
LTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQ
KGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQPL
HIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARND
FSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVR
EALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAV
AAQLPCRDALMQEYDDKWHLDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAED
GSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=389, Percent_Identity=26.4781491002571, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI132814467, Length=410, Percent_Identity=27.3170731707317, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI61742777, Length=376, Percent_Identity=25.7978723404255, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI61742775, Length=376, Percent_Identity=25.7978723404255, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI194239713, Length=353, Percent_Identity=28.328611898017, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI194306629, Length=497, Percent_Identity=24.5472837022133, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI11641261, Length=497, Percent_Identity=24.5472837022133, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310123622, Length=347, Percent_Identity=26.5129682997118, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310133497, Length=347, Percent_Identity=26.5129682997118, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI7019561, Length=336, Percent_Identity=27.3809523809524, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI94818901, Length=370, Percent_Identity=24.5945945945946, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI94818891, Length=370, Percent_Identity=24.5945945945946, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4505029, Length=457, Percent_Identity=25.164113785558, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI157266300, Length=211, Percent_Identity=27.4881516587678, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI1787163, Length=870, Percent_Identity=98.9655172413793, Blast_Score=1798, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=475, Percent_Identity=25.8947368421053, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71989071, Length=475, Percent_Identity=25.8947368421053, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17569221, Length=385, Percent_Identity=25.1948051948052, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17569225, Length=289, Percent_Identity=27.3356401384083, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115533276, Length=373, Percent_Identity=26.0053619302949, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533278, Length=373, Percent_Identity=26.0053619302949, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565628, Length=404, Percent_Identity=26.980198019802, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193206928, Length=368, Percent_Identity=26.3586956521739, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193206926, Length=368, Percent_Identity=26.3586956521739, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI133903840, Length=378, Percent_Identity=24.3386243386243, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71990873, Length=327, Percent_Identity=23.2415902140673, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=345, Percent_Identity=26.3768115942029, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321837, Length=385, Percent_Identity=26.7532467532467, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324283, Length=455, Percent_Identity=23.956043956044, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655252, Length=478, Percent_Identity=25.3138075313808, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24655257, Length=478, Percent_Identity=25.3138075313808, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24655274, Length=478, Percent_Identity=25.3138075313808, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24655260, Length=478, Percent_Identity=25.3138075313808, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24655265, Length=478, Percent_Identity=25.3138075313808, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24655268, Length=478, Percent_Identity=25.3138075313808, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646516, Length=369, Percent_Identity=27.10027100271, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646518, Length=385, Percent_Identity=27.012987012987, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646514, Length=349, Percent_Identity=27.5071633237822, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24651025, Length=386, Percent_Identity=26.9430051813472, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651023, Length=386, Percent_Identity=26.9430051813472, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651021, Length=386, Percent_Identity=26.9430051813472, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21358341, Length=304, Percent_Identity=28.2894736842105, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221379089, Length=337, Percent_Identity=28.1899109792285, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651016, Length=241, Percent_Identity=28.6307053941909, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648786, Length=370, Percent_Identity=25.4054054054054, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646512, Length=284, Percent_Identity=25, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646510, Length=284, Percent_Identity=25, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571901, Length=382, Percent_Identity=24.0837696335079, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161078673, Length=382, Percent_Identity=24.0837696335079, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550850, Length=378, Percent_Identity=25.1322751322751, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650973, Length=378, Percent_Identity=25.1322751322751, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571792, Length=361, Percent_Identity=24.3767313019391, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330574, Length=224, Percent_Identity=30.8035714285714, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648784, Length=381, Percent_Identity=22.8346456692913, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648790, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584504, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 98912; Mature: 98781

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLDGEDLK
CCCCCCCHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCEE
LVSVHINDEPWTAWKEEEGALVISNLPERFTLKIVNEISPATNTALEGLYQSGDALCTQC
EEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
EAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGNRVAQGELENGRHWVQWQDPF
HHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCEEEEECCCC
PKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEER
CCCCEEEEEHHCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
FGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYF
CCCEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEEECCCCCCCHHHHHHHHHHHHHH
HNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPM
HCCCCCEEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
AHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDD
CCCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCHHH
FVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQP
HHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCC
LHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPV
EECEEEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCE
KLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFR
EEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
AVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADELLAIY
HHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAA
CCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAAQLPCRDALMQEYDDKWHLDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPN
HHHCCCHHHHHHHHCCCCCCCCCEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHH
RIRSLIGAFAGSNPAAFHAEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKR
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHH
QEKMRAALEQLKGLENLSGDLYEKITKALA
HHHHHHHHHHHHCHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLDGEDLK
CCCCCCHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCCEE
LVSVHINDEPWTAWKEEEGALVISNLPERFTLKIVNEISPATNTALEGLYQSGDALCTQC
EEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
EAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGNRVAQGELENGRHWVQWQDPF
HHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCEEEEECCCC
PKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEER
CCCCEEEEEHHCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
FGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYF
CCCEECCCEEEEEEEHHHCCCCCCCCCCEEECCEEEEEECCCCCCCHHHHHHHHHHHHHH
HNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPM
HCCCCCEEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
AHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDD
CCCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCHHH
FVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQP
HHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCC
LHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPV
EECEEEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCE
KLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFR
EEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
AVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADELLAIY
HHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAA
CCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VAAQLPCRDALMQEYDDKWHLDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPN
HHHCCCHHHHHHHHCCCCCCCCCEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHH
RIRSLIGAFAGSNPAAFHAEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKR
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHH
QEKMRAALEQLKGLENLSGDLYEKITKALA
HHHHHHHHHHHHCHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]