Click here to switch to the map view.

The map label for this gene is tsx2 [H]

Identifier: 170682215

GI number: 170682215

Start: 4471225

End: 4472085

Strand: Reverse

Name: tsx2 [H]

Synonym: EcSMS35_4384

Alternate gene names: 170682215

Gene position: 4472085-4471225 (Counterclockwise)

Preceding gene: 170683900

Following gene: 170684185

Centisome position: 88.23

GC content: 40.07

Gene sequence:

>861_bases
ATGTGTATAAAAAAGCACGGGATAGCTTTATCGATTCTATTAATACCTTGCATTGGAAACGCTCAGGAAATTAAAAGTGA
GGAAGGCTGGTTACATCAAAGCTTGAATGTCATTGGTCGCACAGACTCTCGCTTTGGCCCAAGGCTGACTAACGACCTCT
ACCCTGAATATACTGTAGCAGGAAGAAAAGACTGGTTTGATTTTTATGGTTATGTTGATCTACCAAAATTCTTTGGCGTC
GGCAGTCACTATGATGTTGGGATCTGGGATGAGGGCTCACCACTATTTACGGAAATAGAACCTCGGTTTTCCATTGACAA
ATTGACCGGATTAAATCTTGCGTTCGGCCCTTTTAAAGAATGGTTCATTGCAAACAACTATGTCTATGATATGGGTGACA
ACCAGTCATCCCGGCAAAGTACATGGTATATGGGGCTTGGTACAGATATCGACACGGGTCTACCAATTAAGCTTTCTGCC
AATATATACGCCAAGTATCAGTGGCAAAACTATGGTGCCGCTAATGAAAATGAATGGGACGGATATCGATTCAAAATAAA
ATATAGCATTCCTCTTACCCATTTATTCGGAGGGCGATTGGTATACAATAGTTTTACTAACTTTGATTTTGGCTCCGATC
TTGCGGACAAATCACACAATAATAAACGAACCAGTAATGCTATTGCTTCAAGCCATATCCTTTCCCTGCTATATGAACAC
TGGAAATTTGCATTTACACTACGTTATTTTCACAACGGTGGACAATGGAATGCTGGGGAGAAAGTTAACTTCGGAGATGG
TCCATTTGAATTAAAAAACACAGGATGGGGAACCTATACTACTATTGGTTATCAATTTTAA

Upstream 100 bases:

>100_bases
TGCGGGTGGACGTTAGCAAATAATAAAAAAATTATAATGCCATTCATTCACTGAATGGCATTATTTTCTCTAAATCAACA
ATAGATAATGAGATATATTT

Downstream 100 bases:

>100_bases
ATCAGGTGATGTTTTAGATATTTTTACTTAATGCCATTTTGTAATTGTCATAAATAACTTCACCATTCACACTGTGAATT
CATCGCTCAACACAAAAGCC

Product: nucleoside-specific channel-forming protein Tsx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MCIKKHGIALSILLIPCIGNAQEIKSEEGWLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGV
GSHYDVGIWDEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTDIDTGLPIKLSA
NIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTHLFGGRLVYNSFTNFDFGSDLADKSHNNKRTSNAIASSHILSLLYEH
WKFAFTLRYFHNGGQWNAGEKVNFGDGPFELKNTGWGTYTTIGYQF

Sequences:

>Translated_286_residues
MCIKKHGIALSILLIPCIGNAQEIKSEEGWLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGV
GSHYDVGIWDEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTDIDTGLPIKLSA
NIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTHLFGGRLVYNSFTNFDFGSDLADKSHNNKRTSNAIASSHILSLLYEH
WKFAFTLRYFHNGGQWNAGEKVNFGDGPFELKNTGWGTYTTIGYQF
>Mature_286_residues
MCIKKHGIALSILLIPCIGNAQEIKSEEGWLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGV
GSHYDVGIWDEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTDIDTGLPIKLSA
NIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTHLFGGRLVYNSFTNFDFGSDLADKSHNNKRTSNAIASSHILSLLYEH
WKFAFTLRYFHNGGQWNAGEKVNFGDGPFELKNTGWGTYTTIGYQF

Specific function: Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides [H]

COG id: COG3248

COG function: function code M; Nucleoside-binding outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786612, Length=262, Percent_Identity=64.5038167938931, Blast_Score=353, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003055
- InterPro:   IPR018013 [H]

Pfam domain/function: PF03502 Channel_Tsx [H]

EC number: NA

Molecular weight: Translated: 32769; Mature: 32769

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIKKHGIALSILLIPCIGNAQEIKSEEGWLHQSLNVIGRTDSRFGPRLTNDLYPEYTVA
CCCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCEEEC
GRKDWFDFYGYVDLPKFFGVGSHYDVGIWDEGSPLFTEIEPRFSIDKLTGLNLAFGPFKE
CCCCCHHHCCEEECHHHHCCCCCCEEEEECCCCCCEEECCCCCCHHHCCCCEEECCCCHH
WFIANNYVYDMGDNQSSRQSTWYMGLGTDIDTGLPIKLSANIYAKYQWQNYGAANENEWD
HEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCC
GYRFKIKYSIPLTHLFGGRLVYNSFTNFDFGSDLADKSHNNKRTSNAIASSHILSLLYEH
CEEEEEEEECCHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
WKFAFTLRYFHNGGQWNAGEKVNFGDGPFELKNTGWGTYTTIGYQF
HEEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEEC
>Mature Secondary Structure
MCIKKHGIALSILLIPCIGNAQEIKSEEGWLHQSLNVIGRTDSRFGPRLTNDLYPEYTVA
CCCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCEEEC
GRKDWFDFYGYVDLPKFFGVGSHYDVGIWDEGSPLFTEIEPRFSIDKLTGLNLAFGPFKE
CCCCCHHHCCEEECHHHHCCCCCCEEEEECCCCCCEEECCCCCCHHHCCCCEEECCCCHH
WFIANNYVYDMGDNQSSRQSTWYMGLGTDIDTGLPIKLSANIYAKYQWQNYGAANENEWD
HEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCC
GYRFKIKYSIPLTHLFGGRLVYNSFTNFDFGSDLADKSHNNKRTSNAIASSHILSLLYEH
CEEEEEEEECCHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
WKFAFTLRYFHNGGQWNAGEKVNFGDGPFELKNTGWGTYTTIGYQF
HEEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]