Click here to switch to the map view.

The map label for this gene is yeeJ [C]

Identifier: 170681535

GI number: 170681535

Start: 2729183

End: 2731357

Strand: Reverse

Name: yeeJ [C]

Synonym: EcSMS35_2661

Alternate gene names: 170681535

Gene position: 2731357-2729183 (Counterclockwise)

Preceding gene: 170680650

Following gene: 170680922

Centisome position: 53.89

GC content: 47.63

Gene sequence:

>2175_bases
ATGCTGCGATGGACACGCTGTATTATGCTAACATTTATCTCTGGGGCTGCTTTTGCGGCTCCAGAGATAAATGTTGAGCA
TAAAGAATCATTACCTGATTTAGGTAGTCAGGCCGCACAACAAGAAGAACAAACCAACAAGGGGAAATCGCTAAAAGAGC
GTGGTGCCGATTACGTCATTAACTCCGCTACGCAAGGGTTTGAAAACCTGACACCCGAGGCGCTGGAGTCCCAGGCCAGA
AGCTATCTGCAAAGTCAAATTACCTCTACGACACAATCTTATATTGAGGATACACTCTCCCCCTACGGTAAGGTTCGAAC
GAATCTTTCTCTTGGCCAGGGCGGCGATCTGGATGGCAGTTCCATCGACTATTTTGTTCCCTGGTATGATAATCAAACTA
CTGTTTATTTCAGCCAATTTTCTGCACAACGAAAAGAAGATCGTACGATCGGGAATATTGGGCTTGGTGTAAGACATAAT
TTTGATAAATGGTTGTTGGGTGGAAATATATTTTATGATTATGATTTTACCCGTGGGCATCGCCGTTTAGGTTTAGGTGT
CGAAGCGTGGACTGATTATTTAAAATTCTCTGGCAACTATTATCACCCGCTTTCTGACTGGAAAGACTCCGAAGATTTCG
ATTTTTATGAGGAGCGTCCTGCGCGCGGCTGGGATATTCGCGCCGAAGCCTGGCTTCCCGCTTATCCGCAGCTTGGTGGT
AAAATTGTTTTCGAACAGTATTACGGTAATGAAGTCGCGCTTTTTGGCACTGATAATCTGGAGAAAGATCCCTTCGCTGT
CACGCTGGGTGTGAAATACCAGCCCGTTCCGCTCATTGCTGTCGGTACAGATTTCAAAGCTGGCACTGGCGATAATACCG
ATCTTTCTGTTAACGCAACGCTTAATTATCAGTTTGGCGTCCCGCTCAAAGACCAGCTTGATCCTGACAAAGTGAGCGCT
GCTCACTCGCTTATGGGCAGCCGTCATGACTTTGTTGAACGTAACAACTTTATTGTTCTGGAATACAAAGAAAAAGATCC
CCTCGACGTCACTTTGTGGCTGAAAGCCGACGCCACGAATGAACATCCCGAGTGCGTGATTAAAGATACGCCTGAAGAAG
CTATCGGGCTGGAAAAATGTAAATGGACCATTAACGCGCTCATTAACCATCACTACAAAATCGTCGCTGCCTCCTGGCAG
GCGAAAAACAATGCTGCACGTACGCTGGTGATGCCGGTTATCAAAGAAAACACGCTTACCGAAGGTAACAACAACCACTG
GAATCTGGTGCTGCCTGCCTGGCAGTACAGTTCTGATAAAGCCGAACAAGAAAAACTCAATACCTGGCGGGTTCGTCTGG
CGCTGGAAGATGAAAAAGGTAATCGACAGAATTCCGGCGTGGTGGAAATCACCGTTCAGCAGGATCGCAAAATTGAGCTC
ATCGTTAACAACATCGCCGATGTACCAGATGAGAACAATCACAGTCATGAAGCCAGCGCACAGGCCGATGGTGTAGATGG
TGTGGTGATGGATCTCGATATTACTGATAGCTTTGGCGACAACACTGACCGCAACGGTAATGTCTTGCCGCAGGATAATC
TCAACCCGCAGTTGTTTGACGCCAACGATAAAAAAGTGACGCTGACGAATAAACCCTGCACTACCGAGACTCCCTGTGTC
TTTATCGCCAAACAAGATAAAGAAAAGGGGACCGTTACGCTCTCCAGTACATTGCCTGGCACCTTCCGTTGGAAGGCGAA
AGCCGCTCCCTATGATGACAGTAACTATGTTGACGTAACGTTCCTGGGTTCTGACATCGGCGGGCTGAATGCCTTTATCT
ATCGTGTTGGTGCGGCTAAGCCCGTGAATCTTATCGGCAATAAAGAGCCGTTGCCTCTCAATAGCAGCTATCGCTTTGTG
TTGTGGCGTGACGCTAACAAAGACGGCGTGTTCCAGCTATCAGAGAAATTCACTGAAGAGGAGATGAAACAGTATGACTA
TCAGTGGGAATTCACGGGACATAGCGTGAATGGCAATACCGGTGCGCAAGCCAATACCACTAACGCCGATATAGAGATCC
CGGCAACGAACAAGGACGCGGCAACGAAGTTTAGTGCCCAGGTAACCGATGGCGTGCAGGGATACGGTTTGCAGGTCAAT
TACAGCAAGAAATAG

Upstream 100 bases:

>100_bases
AATAATGATATATTTATCCTTTCTGGCATGCCTTTCTGAATAATCAGGGATACAATATTAAAGCTTATTTTTGACTTTAT
CATTGTCACAGGAAAAGTGC

Downstream 100 bases:

>100_bases
GATCAGCGCCATGGCTGATCGGGCCACCGCTGAATGTTAACCAAGGAGAGTGTTTATGAAACCTCATATGAAACGTGGCC
TGACAAGAGTCGCGCTGGCA

Product: putative adhesin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEALESQAR
SYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
FDKWLLGGNIFYDYDFTRGHRRLGLGVEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGG
KIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLDPDKVSA
AHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQ
AKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQDRKIEL
IVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNKPCTTETPCV
FIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFV
LWRDANKDGVFQLSEKFTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVN
YSKK

Sequences:

>Translated_724_residues
MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEALESQAR
SYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
FDKWLLGGNIFYDYDFTRGHRRLGLGVEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGG
KIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLDPDKVSA
AHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQ
AKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQDRKIEL
IVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNKPCTTETPCV
FIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFV
LWRDANKDGVFQLSEKFTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVN
YSKK
>Mature_724_residues
MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLTPEALESQAR
SYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
FDKWLLGGNIFYDYDFTRGHRRLGLGVEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGG
KIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLDPDKVSA
AHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQ
AKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQDRKIEL
IVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNKPCTTETPCV
FIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFV
LWRDANKDGVFQLSEKFTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVN
YSKK

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=407, Percent_Identity=34.8894348894349, Blast_Score=255, Evalue=8e-69,
Organism=Escherichia coli, GI145693120, Length=444, Percent_Identity=31.3063063063063, Blast_Score=202, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 81148; Mature: 81148

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVI
CCCHHHHHHHHHHCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEE
NSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGS
ECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCC
SIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHNFDKWLLGGNIFYDYDFTRGH
CEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCCCEECCCCCEEECCEEEEEECCCCCC
RRLGLGVEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGG
EEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCC
KIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNAT
EEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCCCCCEEEEEEE
LNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATN
EEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEEEEEEEECCCC
EHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLVMPVIKENTLT
CCCCEEEECCCHHHHCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCCCC
EGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQDRKIEL
CCCCCEEEEEEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEE
IVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFD
EEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEC
ANDKKVTLTNKPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVT
CCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEE
FLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFVLWRDANKDGVFQLSEKFTEE
EECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHH
EMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVN
HHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEECCCCCCCEEEEE
YSKK
ECCC
>Mature Secondary Structure
MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVI
CCCHHHHHHHHHHCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEE
NSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGS
ECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCC
SIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHNFDKWLLGGNIFYDYDFTRGH
CEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCCCEECCCCCEEECCEEEEEECCCCCC
RRLGLGVEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGG
EEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCC
KIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNAT
EEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCCCCCEEEEEEE
LNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATN
EEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEEEEEEEECCCC
EHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLVMPVIKENTLT
CCCCEEEECCCHHHHCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCCCC
EGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEITVQQDRKIEL
CCCCCEEEEEEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEE
IVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFD
EEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEC
ANDKKVTLTNKPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVT
CCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEE
FLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFVLWRDANKDGVFQLSEKFTEE
EECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHH
EMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVN
HHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEECCCCCCCEEEEE
YSKK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]