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The map label for this gene is exoX

Identifier: 170681411

GI number: 170681411

Start: 1333311

End: 1333973

Strand: Reverse

Name: exoX

Synonym: EcSMS35_1342

Alternate gene names: 170681411

Gene position: 1333973-1333311 (Counterclockwise)

Preceding gene: 170683686

Following gene: 170684011

Centisome position: 26.32

GC content: 51.89

Gene sequence:

>663_bases
ATGTTGCGCATTATCGATACAGAAACCTGCGGTTTGCAGGGAGGGATCGTTGAGATTGCCTCTGTTGATGTCATTGACGG
AAAAATCGTCAACCCCATGAGCCACCTGGTGCGCCCCGATCGTCCTATTAGTCCACAAGCGATGGCGATTCATCGCATCA
CCGAAGCCATGGTCGCCGATAAACCGTGGATTGAAGATGTGATCCCGCACTATTACGGTAGTGAATGGTATGTCGCGCAC
AACGCCAGCTTTGACCGCCGCGTACTGCCTGAGATGCCCGGTGAGTGGATTTGCACTATGAAACTGGCCCGTCGTTTGTG
GCCAGGGATCAAGTATAGCAATATGGCGTTATATAAAACACGGAAGCTCAATGTACAGACGCCGCCGGGCCTGCATCATC
ACCGCGCGTTGTATGACTGTTATATCACCGCTGCGTTGCTTATCGATATTATGAACACCTCCGGCTGGACGGCAGAACAG
ATGGCCGATATCACCGGACGTCCGTCGTTGATGACGACCTTCACCTTTGGCAAATACCGTGGCAAAGCGGTTTCCGACGT
TGCCGAACGCGATCCGGGCTATCTGCGCTGGTTGTTTAATAACCTGGACAGCATGAGCCCGGAGCTGCGTTTAACACTGA
AACATTATCTGGAAAATACTTAA

Upstream 100 bases:

>100_bases
CCGATCGTGGTTCATTATTGTTAGTCGGTCAGCGTTCATCACAGGGTTGGCAAGGCGATATCATTCCATTACGCTAGGCT
TTTTCGGCCTGGAGCATGCC

Downstream 100 bases:

>100_bases
TCCTCAGGCGTAGCGGGTAATGTTCCCTGCGCCAGCGCGACCAGAAAAGCATATTCCATCGCTACGCCTTCGTACGATTT
AAAGCGGCCAGATTTACCGC

Product: exodeoxyribonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT

Sequences:

>Translated_220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
>Mature_220_residues
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=220, Percent_Identity=100, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EXOX_ECOL6 (P0AEK1)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_754148.2
- ProteinModelPortal:   P0AEK1
- SMR:   P0AEK1
- EnsemblBacteria:   EBESCT00000041919
- GeneID:   1036778
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c2254
- GeneTree:   EBGT00050000009156
- HOGENOM:   HBG416046
- OMA:   QEMERIG
- ProtClustDB:   PRK07983
- GO:   GO:0005622
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.11.- [C]

Molecular weight: Translated: 25133; Mature: 25133

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKT
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEE
RKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQMADITGRPSLMTTFTFGKYR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCC
GKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
CCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPISPQAMAIHRITEAMVAD
CEEEEECCCCCCCCCEEEEEEEEEECCEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKT
CCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEEEEEE
RKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQMADITGRPSLMTTFTFGKYR
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCCC
GKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
CCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157