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The map label for this gene is dmsB_2 [H]

Identifier: 170680702

GI number: 170680702

Start: 2243194

End: 2243811

Strand: Reverse

Name: dmsB_2 [H]

Synonym: EcSMS35_2225

Alternate gene names: 170680702

Gene position: 2243811-2243194 (Counterclockwise)

Preceding gene: 170680161

Following gene: 170683650

Centisome position: 44.27

GC content: 52.27

Gene sequence:

>618_bases
ATGACAACCCAGTATGGATTTTTTATTGATTCCAGCCGTTGCACCGGTTGCAAAACCTGCGAGCTGGCCTGTAAAGACTA
CAAAGATTTGACGCCAGAAGTCAGTTTCCGCCGCATTTATGAATATGCTGGCGGCGACTGGCAGGAAGATAACGGTGTCT
GGCACCAGAACGTGTTTGCCTACTATCTGTCGATTTCATGTAACCACTGCGAAGATCCGGCTTGTACTAAAGTCTGCCCG
AGCGGTGCGATGCATAAACGTGAAGATGGTTTTGTTGTGGTCGATGAAGATGTGTGCATTGGCTGCCGCTACTGCCATAT
GGCTTGCCCGTATGGCGCACCGCAATATAACGAAACGAAAGGCCGTATGACCAAATGCGATGGTTGTTATGACCGTGTTG
CGGAGGGGAAAAAGCCGATCTGTGTTGAATCTTGCCCGCTGCGGGCGCTGGATTTCGGCCCTATCGACGAGCTGCGTAAA
AAACATGGCGATCTGGCGGCCGTTGCGCCGTTGCCGCGAGCTCACTTTACCAAACCGAATATTGTGATCAAACCCAATGC
CAACAGCCGCCCGACCGGGGATACCACTGGCTATCTGGCAAACCCGAAGGAGGTGTGA

Upstream 100 bases:

>100_bases
TGTATCAACGTACTGACCACTCAACGTCCGTCTCCTCTCGCTAAGGGGAATCCGTCACATACAAACCTTGTTCAGGTTGA
AAAGGTGTAAGGAGTAACCG

Downstream 100 bases:

>100_bases
GATGGGAAGTGGATGGCATGAATGGCCGCTGATGATCTTCACGGTCTTCGGGCAATGTGTAGCGGGTGGTTTTATCGTTC
TGGCTTTGGCGCTGCTCAAA

Product: dimethylsulfoxide reductase, B subunit

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCP
SGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGRMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV

Sequences:

>Translated_205_residues
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCP
SGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGRMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV
>Mature_204_residues
TTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPS
GAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGRMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRKK
HGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=205, Percent_Identity=99.5121951219512, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1787872, Length=205, Percent_Identity=93.6585365853659, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1787749, Length=164, Percent_Identity=35.9756097560976, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789370, Length=198, Percent_Identity=33.8383838383838, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI226510944, Length=155, Percent_Identity=38.7096774193548, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790326, Length=161, Percent_Identity=32.2981366459627, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI2367345, Length=188, Percent_Identity=33.5106382978723, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367245, Length=163, Percent_Identity=32.5153374233129, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1787478, Length=99, Percent_Identity=43.4343434343434, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787740, Length=101, Percent_Identity=41.5841584158416, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789067, Length=177, Percent_Identity=32.7683615819209, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87082179, Length=162, Percent_Identity=31.4814814814815, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788811, Length=158, Percent_Identity=31.6455696202532, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787963, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI87082180, Length=153, Percent_Identity=28.7581699346405, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22888; Mature: 22757

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
9.8 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFA
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHCEEE
YYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETK
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEECCHHHEEECCCCCCCCCCCC
GRMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRKKHGDLAAVAPLPRAHFTKPN
CCEECCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCC
IVIKPNANSRPTGDTTGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFA
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHCEEE
YYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETK
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEECCHHHEEECCCCCCCCCCCC
GRMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRKKHGDLAAVAPLPRAHFTKPN
CCEECCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCC
IVIKPNANSRPTGDTTGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]