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The map label for this gene is mglC [H]

Identifier: 170680415

GI number: 170680415

Start: 2322457

End: 2323467

Strand: Reverse

Name: mglC [H]

Synonym: EcSMS35_2295

Alternate gene names: 170680415

Gene position: 2323467-2322457 (Counterclockwise)

Preceding gene: 170679772

Following gene: 170680883

Centisome position: 45.84

GC content: 50.15

Gene sequence:

>1011_bases
ATGAGTGCGTTAAATAAGAAAAGTTTTCTTACTTACCTGAAAGAAGGCGGTATTTACGTCGTTCTTTTAGTTTTGCTGGC
AATTATTATTTTCCAGGACCCAACATTTTTAAGTCTGTTGAACTTAAGTAATATTCTCACCCAGTCATCGGTGCGTATTA
TTATCGCGCTCGGTGTGGCAGGGTTAATTGTCACCCAGGGGACCGACCTTTCTGCAGGTCGCCAGGTGGGGCTGGCGGCA
GTAGTAGCGGCGACGTTGTTGCAGTCCATGGATAACGCCAACAAAGTGTTCCCGGAAATGGCGACGATGCCGATTGCGCT
GGTTATTCTGATTGTCTGTGCCATTGGTGCGGTGATCGGTTTGATTAACGGCCTGATTATCGCTTATCTCAACGTGACGC
CATTCATTACCACGCTCGGCACGATGATCATCGTCTATGGCATCAACTCGCTCTATTACGACTTTGTCGGGGCGTCGCCA
ATTTCTGGTTTTGACAGTGGCTTCTCTACCTTTGCTCAGGGCTTTGTCGCGCTGGGGAGTTTCCGTCTCTCTTACATCAC
CTTCTATGCGTTGATTGCGGTGGTGTTTGTCTGGGTGTTGTGGAACAAAACCCGCTTCGGTAAGAACATTTTTGCCATTG
GCGGTAACCCGGAAGCGGCGAAAGTATCTGGTGTCAACGTCGGCCTGAACCTGCTGATGATCTACGCGTTGTCTGGTGTG
TTCTATGCCTTCGGCGGGATGTTAGAAGCCGGACGTATCGGCTCAGCCACCAATAACCTCGGCTTTATGTATGAGCTGGA
TGCTATCGCGGCGTGCGTGGTAGGCGGCGTATCGTTCAGCGGCGGTGTGGGGACGGTGATTGGCGTGGTGACCGGGGTAA
TTATTTTTACCGTCATCAACTATGGCCTGACGTATATCGGCGTAAACCCATACTGGCAGTACATCATCAAAGGGGCGATT
ATTATCTTCGCCGTAGCGCTGGATTCACTGAAATACGCGCGTAAGAAATGA

Upstream 100 bases:

>100_bases
GAGCAATGGTCTCGTTTCCGGAATTGTCGATACAAAAACAACAACGCAAAACGAAATTCTGCGTCTTGCGTCTTTGCACC
TTTAAGATTAGGGGCTTCCC

Downstream 100 bases:

>100_bases
TGTGAATGTGGGTATTGCCGGATGCGCTGCATCCGGCATTCGGTGCCAAATGCCGGATGTGACGCGGGTTCTACAACGTT
ACCGGGTGTTCTTTCTCGCC

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK

Sequences:

>Translated_336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK
>Mature_335_residues
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAV
VAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPI
SGFDSGFSTFAQGFVALGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGVF
YAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAII
IFAVALDSLKYARKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=99.7023809523809, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=323, Percent_Identity=34.984520123839, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789992, Length=376, Percent_Identity=30.8510638297872, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790524, Length=332, Percent_Identity=33.433734939759, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788896, Length=332, Percent_Identity=31.9277108433735, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693152, Length=321, Percent_Identity=30.2180685358255, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787794, Length=304, Percent_Identity=31.9078947368421, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787793, Length=307, Percent_Identity=29.6416938110749, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=31.9078947368421, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693214, Length=269, Percent_Identity=31.5985130111524, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35579; Mature: 35448

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHH
GLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSGFSTFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHH
GLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSGFSTFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1719366; 9278503 [H]