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The map label for this gene is norR [H]

Identifier: 170679621

GI number: 170679621

Start: 2906002

End: 2907516

Strand: Reverse

Name: norR [H]

Synonym: EcSMS35_2831

Alternate gene names: 170679621

Gene position: 2907516-2906002 (Counterclockwise)

Preceding gene: 170680945

Following gene: 170680146

Centisome position: 57.37

GC content: 57.23

Gene sequence:

>1515_bases
ATGAGTTTTTCCGTTGATGTGCTGGCGAATATCGCCATCGAATTGCAGCGTGGGATTGGTCATCAGGATCGTTTTCAGCG
CCTGATCACCACGCTGCGTCAGGTGCTGGAGTGTGATGCCTCTGCGTTGCTACGTTATGACTCGCGGCAGTTTATTCCGC
TTGCCATCGACGGGCTGGCGAAGGATGTACTCGGTAGACGCTTTGCGCTGGAAGGGCATCCACGGCTGGAAGCGATTGCC
CGCGCCGGGGACGTGGTGCGCTTTCCCGCAGACAGCGAATTGCCCGATCCCTATGACGGTTTGATTCCCGGGCAGGAGAG
TCTGAAGGTTCACGCCTGCGTTGGTCTGCCATTGTTTGCCGGGCAAAACCTGATCGGCGCATTGACGCTCGACGGGATGC
AGCCCGATCAGTTCGATGTTTTCAGCGACGAAGAGTTACGCCTGATTGCCGCGCTGGCGGCGGGAGCGTTAAGCAATGCG
TTGCTGATTGAGCAACTGGAAAGCCAGAATATGCTGCCGGGCGATGCCGCGCCGTTTGAAGCGGTGAAACAGACGCAGAT
GATCGGTCTGTCGCCAGGCATGACGCAATTGAAAAAAGAGATTGAGATTGTGGCGGCGTCCGATCTCAACGTCTTAATCA
GCGGTGAGACGGGAACCGGTAAGGAGCTGGTGGCGAAAGCGATTCATGAAGCCTCGCCAAGGGCGGTGAATCCGCTGGTC
TATCTCAACTGTGCCGCACTGCCGGAAAGTGTGGCGGAAAGTGAGTTGTTCGGGCACGTGAAAGGGGCGTTTACTGGCGC
TATCAGTAACCGCAGCGGGAAGTTTGAAATGGCGGATAACGGCACGCTGTTTCTGGATGAGATCGGCGAGTTGTCGTTGG
CATTGCAGGCCAAGCTGCTGCGGGTGTTGCAGTATGGCGATATTCAGCGCGTTGGCGATGACCGCAGTTTGCGGGTCGAT
GTGCGCGTGCTGGCGGCGACTAACCGTGACTTACGCGAAGAGGTACTGGCAGGGCGATTTCGCGCTGACTTGTTCCACCG
CCTGAGCGTGTTTCCACTTTCAGTGCCGCCGCTGCGTGAGCGGGGCGATGATGTCATTCTGCTGGCGGGGTATTTCTGCG
AACAGTGCCGCCTGCGGTTGGGGCTCTCCCGCGTGGTATTAAGTGCCAGAGCGCGAAATTTACTGCAACACTACAATTTT
CCGGGGAACGTTCGTGAACTGGAACATGCTATTCATCGGGCGGTAGTGCTGGCGAGAGCCACTCGCAGCGGCGATGAAGT
GATTCTTGAAGCGCAACATTTTGCTTTTCCTGAGGTGACGTTGCCGCCGCCAGAAGCGGCGGCGGTGCCTATCGTTAAGC
AAAACCTGCGTGAAGCGACAGAAGCGTTCCAGCGTGAAACCATTCGTCAGGCACTGGCACAAAATCATCACAACTGGGCT
GCCAGCGCACGGATGCTGGAAACCGACGTCGCCAACTTGCATCGGTTGGCGAAACGTCTGGGGCTGAAGGATTAA

Upstream 100 bases:

>100_bases
TGTATAAATTAATTCATGCTCATTAATGAGTAGTCAAAATGACTATTAATCAAATGGTCGATATGACAATATCTATAGTC
AAATTGACAGTGAGGCAAAG

Downstream 100 bases:

>100_bases
ATAATCCCGGCCTGATAGAAATCCTGCAGGTTAATTGCGCCGGTGAGTTTGCCGTTTTCATCCACTACCGGTGCGGCGGT
GATTTTGCGTTTCATCAGGA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNF
PGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD

Sequences:

>Translated_504_residues
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNF
PGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD
>Mature_503_residues
SFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIAR
AGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNAL
LIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVY
LNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDV
RVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNFP
GNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWAA
SARMLETDVANLHRLAKRLGLKD

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=504, Percent_Identity=98.2142857142857, Blast_Score=993, Evalue=0.0,
Organism=Escherichia coli, GI1789087, Length=357, Percent_Identity=40.8963585434174, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=47.1518987341772, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=47.1153846153846, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788550, Length=299, Percent_Identity=45.819397993311, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790299, Length=336, Percent_Identity=40.7738095238095, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=39.5569620253165, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1789233, Length=333, Percent_Identity=39.3393393393393, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=39.1304347826087, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787583, Length=338, Percent_Identity=37.5739644970414, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=243, Percent_Identity=46.5020576131687, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789828, Length=248, Percent_Identity=36.2903225806452, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081858, Length=207, Percent_Identity=34.2995169082126, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55268; Mature: 55137

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCEEEEEHHHHHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNFPGNVRELEHAIHRAVVLARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWA
CCCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCEEEEEHHHHHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNFPGNVRELEHAIHRAVVLARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWA
CCCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA