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The map label for this gene is purE [H]

Identifier: 170079412

GI number: 170079412

Start: 2949666

End: 2950190

Strand: Reverse

Name: purE [H]

Synonym: SYNPCC7002_A2826

Alternate gene names: 170079412

Gene position: 2950190-2949666 (Counterclockwise)

Preceding gene: 170079414

Following gene: 170079411

Centisome position: 98.08

GC content: 52.19

Gene sequence:

>525_bases
ATGAGTGTAATTAATCCCCTGGTTGGCATCATTATGGGGAGCGATTCTGATCTTCCCACGATGGAAGCGGCGATCGCCAT
CTGTAGACAATTTAATATTCCCCACGAGGTTGGCATTGTGTCTGCCCATCGTACCCCGGAGCGCATGGTGGAATACGCCC
AAACAGCCCATGAACGGGGTTTAAAGGTGATTATTGCTGGGGCAGGTGGAGCCGCGCATTTACCGGGGATGGTTGCTGCT
CTGACGCCTTTGCCGGTGATTGGGGTGCCCGTCAAAACCAGTACCCTCAGCGGTGTGGATTCTCTCTACTCCATTGTGCA
AATGCCCCGTGGTATTCCGGTGGCGACAGTGGCGATCGGAAATGCGACCAATGCCGGTTTGTTGGCGGTGCAAATGTTAG
GGGCGTTCGATCCAGCGCTATTGAAACAGGTGCAAGCCTATCGTCAAAGTCTCAAGGAGATGGTGCTCGATAAACAAACT
CAATTAACGGCGATTGGTTATGAGGATTACCTCAAGCAAATGTAG

Upstream 100 bases:

>100_bases
ACCTTCTAAACCAACAAGACGCGCCCTGATCAGGGTTTGTGCAGAGTTCTCCCTTTGTTTATGATGGTTAGTCGGCATGA
CATACATGAGCTAAAAACCT

Downstream 100 bases:

>100_bases
TGTTTTGCAAAATGGAGGAAGTTGCTACAGGAAATTAGTAGATGAGCGACATTGCTTTTGAAGAAACTTTTGTTGATTCT
TTTGTGACCTATTCTGTGGA

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSVINPLVGIIMGSDSDLPTMEAAIAICRQFNIPHEVGIVSAHRTPERMVEYAQTAHERGLKVIIAGAGGAAHLPGMVAA
LTPLPVIGVPVKTSTLSGVDSLYSIVQMPRGIPVATVAIGNATNAGLLAVQMLGAFDPALLKQVQAYRQSLKEMVLDKQT
QLTAIGYEDYLKQM

Sequences:

>Translated_174_residues
MSVINPLVGIIMGSDSDLPTMEAAIAICRQFNIPHEVGIVSAHRTPERMVEYAQTAHERGLKVIIAGAGGAAHLPGMVAA
LTPLPVIGVPVKTSTLSGVDSLYSIVQMPRGIPVATVAIGNATNAGLLAVQMLGAFDPALLKQVQAYRQSLKEMVLDKQT
QLTAIGYEDYLKQM
>Mature_173_residues
SVINPLVGIIMGSDSDLPTMEAAIAICRQFNIPHEVGIVSAHRTPERMVEYAQTAHERGLKVIIAGAGGAAHLPGMVAAL
TPLPVIGVPVKTSTLSGVDSLYSIVQMPRGIPVATVAIGNATNAGLLAVQMLGAFDPALLKQVQAYRQSLKEMVLDKQTQ
LTAIGYEDYLKQM

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=114, Percent_Identity=63.1578947368421, Blast_Score=147, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6324702, Length=172, Percent_Identity=63.953488372093, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 18404; Mature: 18273

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVINPLVGIIMGSDSDLPTMEAAIAICRQFNIPHEVGIVSAHRTPERMVEYAQTAHERG
CCHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCHHHCEEECCCCHHHHHHHHHHHHHCC
LKVIIAGAGGAAHLPGMVAALTPLPVIGVPVKTSTLSGVDSLYSIVQMPRGIPVATVAIG
CEEEEECCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
NATNAGLLAVQMLGAFDPALLKQVQAYRQSLKEMVLDKQTQLTAIGYEDYLKQM
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHCC
>Mature Secondary Structure 
SVINPLVGIIMGSDSDLPTMEAAIAICRQFNIPHEVGIVSAHRTPERMVEYAQTAHERG
CHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCCHHHCEEECCCCHHHHHHHHHHHHHCC
LKVIIAGAGGAAHLPGMVAALTPLPVIGVPVKTSTLSGVDSLYSIVQMPRGIPVATVAIG
CEEEEECCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
NATNAGLLAVQMLGAFDPALLKQVQAYRQSLKEMVLDKQTQLTAIGYEDYLKQM
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]