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The map label for this gene is desA [H]

Identifier: 170079347

GI number: 170079347

Start: 2879706

End: 2880749

Strand: Reverse

Name: desA [H]

Synonym: SYNPCC7002_A2756

Alternate gene names: 170079347

Gene position: 2880749-2879706 (Counterclockwise)

Preceding gene: 170079353

Following gene: 170079344

Centisome position: 95.77

GC content: 48.47

Gene sequence:

>1044_bases
ATGACATCAGTTACTGTGCGCCCTAGTGCCACAACTCTTTTAGAAAAGCATCCAAATCTACGGCTCCGGGATATCCTCGA
TACATTGCCCCGTTCCGTCTACGAAATAAATCCGCTAAAAGCTTGGTCTAGGGTGCTGTTAAGTGTGGCGGCGGTGGTGG
GTTGTTATGCCCTCTTGGCGATCGCCCCTTGGTATTTACTTTTACCCGTTTGGTTTTTAACTGGAACTACCCTAACGGGT
TTTTTTGTGATTGGCCATGATTGCGGCCACCGCTCCTTTTCCCGCAAAAATTGGGTCAATAATTTAGTCGGTCACCTTGC
CTTTTTGCCTTTAATCTATCCTTTCCATAGCTGGCGCATTCTCCATAATCATCACCATCGCTACACCAACAATATGGATG
AGGACAATGCCTGGGCTCCCTTTACCCCTGAGCTATACGATGACTCTCCGGCGTTTATCAAAGCTGTTTACCGGGCGATC
CGGGGCAAACTGTGGTGGCTCGCTTCGGTGATTCACCAACTGAAACTCCACTTCAATTGGTTCGCCTTTGAAGGAAAACA
ACGGGAACAAGTTCGTTTTTCTGCCCTATTTGTGATTATTGCTGGGGCGATCGCCTTTCCGGTGATGTTCTACACCCTCG
GCGTTTGGGGCGTTGTAAAATTCTGGCTGATGCCTTGGCTTGGCTATCATTTCTGGATGAGCACCTTTACCCTCGTGCAC
CACACCGTACCGGAAATTCCCTTTAGCTACCGGGACAAATGGAATGAGGCGATCGCCCAACTGTCTGGAACTGTCCATTG
CGACTATCCCAAGTGGGTTGAAGTCCTTTGCCACGACATCAATGTCCATGTGCCCCACCACCTTTCTACAGGGATTCCCT
CCTACAATCTCCGTAAAGCCTACGCCAGCATCAAGCAAAATTGGGGTGAATATCTCTACGAAACCAAATTTTCTTGGGAG
TTGATGAAAGCGATCACCGAGCAATGTCACCTCTATGACGCTGAGCACAATTACATTTCCTTTGCGCAACATCAAAAACG
CTAA

Upstream 100 bases:

>100_bases
AGACTCGCCAAGAGCCAGACCCGGTAATCGAAAAAAAACGCTTGCATAGTGATCGTGGTATAACCTTTAGAAACCATGTT
ACATTTCGCAAACAATATCA

Downstream 100 bases:

>100_bases
TTTCAGTAAAACAATTTTTTAAAAAACGAAAATATTGCCGACTGAGCTTTTGTTTCGACACCCTAAAACCTAGGGTGTTT
TTTATGTAAAAAAAATCCCC

Product: phosphatidylcholine desaturase

Products: NA

Alternate protein names: Delta(12) desaturase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTSVTVRPSATTLLEKHPNLRLRDILDTLPRSVYEINPLKAWSRVLLSVAAVVGCYALLAIAPWYLLLPVWFLTGTTLTG
FFVIGHDCGHRSFSRKNWVNNLVGHLAFLPLIYPFHSWRILHNHHHRYTNNMDEDNAWAPFTPELYDDSPAFIKAVYRAI
RGKLWWLASVIHQLKLHFNWFAFEGKQREQVRFSALFVIIAGAIAFPVMFYTLGVWGVVKFWLMPWLGYHFWMSTFTLVH
HTVPEIPFSYRDKWNEAIAQLSGTVHCDYPKWVEVLCHDINVHVPHHLSTGIPSYNLRKAYASIKQNWGEYLYETKFSWE
LMKAITEQCHLYDAEHNYISFAQHQKR

Sequences:

>Translated_347_residues
MTSVTVRPSATTLLEKHPNLRLRDILDTLPRSVYEINPLKAWSRVLLSVAAVVGCYALLAIAPWYLLLPVWFLTGTTLTG
FFVIGHDCGHRSFSRKNWVNNLVGHLAFLPLIYPFHSWRILHNHHHRYTNNMDEDNAWAPFTPELYDDSPAFIKAVYRAI
RGKLWWLASVIHQLKLHFNWFAFEGKQREQVRFSALFVIIAGAIAFPVMFYTLGVWGVVKFWLMPWLGYHFWMSTFTLVH
HTVPEIPFSYRDKWNEAIAQLSGTVHCDYPKWVEVLCHDINVHVPHHLSTGIPSYNLRKAYASIKQNWGEYLYETKFSWE
LMKAITEQCHLYDAEHNYISFAQHQKR
>Mature_346_residues
TSVTVRPSATTLLEKHPNLRLRDILDTLPRSVYEINPLKAWSRVLLSVAAVVGCYALLAIAPWYLLLPVWFLTGTTLTGF
FVIGHDCGHRSFSRKNWVNNLVGHLAFLPLIYPFHSWRILHNHHHRYTNNMDEDNAWAPFTPELYDDSPAFIKAVYRAIR
GKLWWLASVIHQLKLHFNWFAFEGKQREQVRFSALFVIIAGAIAFPVMFYTLGVWGVVKFWLMPWLGYHFWMSTFTLVHH
TVPEIPFSYRDKWNEAIAQLSGTVHCDYPKWVEVLCHDINVHVPHHLSTGIPSYNLRKAYASIKQNWGEYLYETKFSWEL
MKAITEQCHLYDAEHNYISFAQHQKR

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17542730, Length=306, Percent_Identity=28.4313725490196, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71999459, Length=333, Percent_Identity=23.7237237237237, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804
- InterPro:   IPR005803 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 40655; Mature: 40524

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00888 CNMP_BINDING_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVTVRPSATTLLEKHPNLRLRDILDTLPRSVYEINPLKAWSRVLLSVAAVVGCYALLA
CCCEECCCCHHHHHHCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHH
IAPWYLLLPVWFLTGTTLTGFFVIGHDCGHRSFSRKNWVNNLVGHLAFLPLIYPFHSWRI
HHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHNHHHRYTNNMDEDNAWAPFTPELYDDSPAFIKAVYRAIRGKLWWLASVIHQLKLHFNW
HHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FAFEGKQREQVRFSALFVIIAGAIAFPVMFYTLGVWGVVKFWLMPWLGYHFWMSTFTLVH
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTVPEIPFSYRDKWNEAIAQLSGTVHCDYPKWVEVLCHDINVHVPHHLSTGIPSYNLRKA
HHCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHH
YASIKQNWGEYLYETKFSWELMKAITEQCHLYDAEHNYISFAQHQKR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TSVTVRPSATTLLEKHPNLRLRDILDTLPRSVYEINPLKAWSRVLLSVAAVVGCYALLA
CCEECCCCHHHHHHCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2118597; 8905231 [H]