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The map label for this gene is prk [H]

Identifier: 170079259

GI number: 170079259

Start: 2795202

End: 2796203

Strand: Reverse

Name: prk [H]

Synonym: SYNPCC7002_A2665

Alternate gene names: 170079259

Gene position: 2796203-2795202 (Counterclockwise)

Preceding gene: 170079261

Following gene: 170079256

Centisome position: 92.96

GC content: 50.7

Gene sequence:

>1002_bases
ATGACCAGTCAGACAGACCGTGTAGTTATTATTGGTGTTGCCGGGGACTCCGGCTGCGGAAAATCTACCTTTTTACGCCG
GCTTACCGATCTGTTCGGCGAAGAGTTCATGACGGTAATCTGCCTTGATGACTACCATAGCCTTGACCGCAAAGGCCGCA
AAGAAGCTGGGGTAACTGCCCTCAATCCCAAGGCCAACAATTTTGATCTCATGGCAGAGCAAATCCGTGATCTAAAAAAC
GGAAAGGCCATTGATAAGCCCATCTACAACCACGAAACCGGGGAAATTGACCCGCCCGAACGCATTGAACCCAACAAAGT
TGTTGTGATCGAAGGGCTACATCCCCTCTACGATGCCCGGGTGCGGGAATTAGTCGATTTCGGCGTGTACCTCGACATCA
GCGATGAAGTCAAAATCCAGTGGAAGATTCAACGAGATATGGCAGAACGGGGCCACACCTACGAGGATGTTCTCGCTTCA
ATTAATGCCCGGAAACCGGATTTCAGCGCCTATATCGAACCCCAACGGGAATTTGCCGATGTGGTGATCCAGGTGCTCCC
CACTGAGCTTGTCGATGACAAAGAAGGAAAATATCTCCGGGTACGCCTCGTCCAAAAAGAAGGAGTTGCAGGCTTCGAAC
CAGCCTATCTCTTTGATGAAGGCTCCACCATCAACTGGCGTCCCTGTGGCCGGAAGCTCACCTGTAACTATCCCGGCATC
AAGATGTACTATGGCCCCGATAACTACTTCGGCAATGAGGTTTCTGTCCTAGAAGTAGACGGGAAATTCGATAATCTCGA
AGAAATGATTTACATCGAAAGCCACCTCAGCAAAACGGGCACCAAGTATTACGGTGAAATGACTGAGCTGCTTCTGAAGC
ACAAGGACTACCCCGGTTCTGACAATGGCACAGGTCTGTTCCAAGTGCTCGTTGGCCTCAAGATGCGCCAAACCTATGAA
TATCTCACCACTGGGAAAGGGGCGATCGCCGCAAGCGTATAG

Upstream 100 bases:

>100_bases
TACACGCCTGAGCCTCGCGAATAAACCGATTCGTCACGAGTTCCCGCCATAGATAACGGATGAGTTTAAAACATAAAATT
TGCAGATCCAGAGGAAATTT

Downstream 100 bases:

>100_bases
AAAAAATCAACACCAATAAGTAGTTGTAGGGGCCTGCCATGGCAAGCCCCTACATTTTTTTTATGGCAATGACGATATAT
GGCGCTTTACATCTGGGATT

Product: phosphoribulokinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTSQTDRVVIIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRKGRKEAGVTALNPKANNFDLMAEQIRDLKN
GKAIDKPIYNHETGEIDPPERIEPNKVVVIEGLHPLYDARVRELVDFGVYLDISDEVKIQWKIQRDMAERGHTYEDVLAS
INARKPDFSAYIEPQREFADVVIQVLPTELVDDKEGKYLRVRLVQKEGVAGFEPAYLFDEGSTINWRPCGRKLTCNYPGI
KMYYGPDNYFGNEVSVLEVDGKFDNLEEMIYIESHLSKTGTKYYGEMTELLLKHKDYPGSDNGTGLFQVLVGLKMRQTYE
YLTTGKGAIAASV

Sequences:

>Translated_333_residues
MTSQTDRVVIIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRKGRKEAGVTALNPKANNFDLMAEQIRDLKN
GKAIDKPIYNHETGEIDPPERIEPNKVVVIEGLHPLYDARVRELVDFGVYLDISDEVKIQWKIQRDMAERGHTYEDVLAS
INARKPDFSAYIEPQREFADVVIQVLPTELVDDKEGKYLRVRLVQKEGVAGFEPAYLFDEGSTINWRPCGRKLTCNYPGI
KMYYGPDNYFGNEVSVLEVDGKFDNLEEMIYIESHLSKTGTKYYGEMTELLLKHKDYPGSDNGTGLFQVLVGLKMRQTYE
YLTTGKGAIAASV
>Mature_332_residues
TSQTDRVVIIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRKGRKEAGVTALNPKANNFDLMAEQIRDLKNG
KAIDKPIYNHETGEIDPPERIEPNKVVVIEGLHPLYDARVRELVDFGVYLDISDEVKIQWKIQRDMAERGHTYEDVLASI
NARKPDFSAYIEPQREFADVVIQVLPTELVDDKEGKYLRVRLVQKEGVAGFEPAYLFDEGSTINWRPCGRKLTCNYPGIK
MYYGPDNYFGNEVSVLEVDGKFDNLEEMIYIESHLSKTGTKYYGEMTELLLKHKDYPGSDNGTGLFQVLVGLKMRQTYEY
LTTGKGAIAASV

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=187, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI57863312, Length=187, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI18699734, Length=187, Percent_Identity=26.2032085561497, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI13899253, Length=190, Percent_Identity=24.7368421052632, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082034, Length=191, Percent_Identity=34.0314136125654, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17539892, Length=180, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17539894, Length=180, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71981181, Length=193, Percent_Identity=29.5336787564767, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324339, Length=170, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550449, Length=180, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573516, Length=180, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573514, Length=180, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573512, Length=180, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221458995, Length=188, Percent_Identity=27.6595744680851, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649624, Length=188, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 37679; Mature: 37548

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00567 PHOSPHORIBULOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQTDRVVIIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRKGRKEAGVTA
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCHHEEEEEEECCHHHHHHCCCHHCCCEE
LNPKANNFDLMAEQIRDLKNGKAIDKPIYNHETGEIDPPERIEPNKVVVIEGLHPLYDAR
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
VRELVDFGVYLDISDEVKIQWKIQRDMAERGHTYEDVLASINARKPDFSAYIEPQREFAD
HHHHHHCCEEEEECCCEEEEEEEEHHHHHCCCCHHHHHHHCCCCCCCCCEEECCHHHHHH
VVIQVLPTELVDDKEGKYLRVRLVQKEGVAGFEPAYLFDEGSTINWRPCGRKLTCNYPGI
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEECCCCE
KMYYGPDNYFGNEVSVLEVDGKFDNLEEMIYIESHLSKTGTKYYGEMTELLLKHKDYPGS
EEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
DNGTGLFQVLVGLKMRQTYEYLTTGKGAIAASV
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
TSQTDRVVIIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRKGRKEAGVTA
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCHHEEEEEEECCHHHHHHCCCHHCCCEE
LNPKANNFDLMAEQIRDLKNGKAIDKPIYNHETGEIDPPERIEPNKVVVIEGLHPLYDAR
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
VRELVDFGVYLDISDEVKIQWKIQRDMAERGHTYEDVLASINARKPDFSAYIEPQREFAD
HHHHHHCCEEEEECCCEEEEEEEEHHHHHCCCCHHHHHHHCCCCCCCCCEEECCHHHHHH
VVIQVLPTELVDDKEGKYLRVRLVQKEGVAGFEPAYLFDEGSTINWRPCGRKLTCNYPGI
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEECCCCE
KMYYGPDNYFGNEVSVLEVDGKFDNLEEMIYIESHLSKTGTKYYGEMTELLLKHKDYPGS
EEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
DNGTGLFQVLVGLKMRQTYEYLTTGKGAIAASV
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]