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The map label for this gene is ndhB

Identifier: 170079141

GI number: 170079141

Start: 2655171

End: 2656751

Strand: Direct

Name: ndhB

Synonym: SYNPCC7002_A2547

Alternate gene names: 170079141

Gene position: 2655171-2656751 (Clockwise)

Preceding gene: 170079138

Following gene: 170079142

Centisome position: 88.27

GC content: 52.56

Gene sequence:

>1581_bases
ATGGATTTTTCAAGCACTGTGGCAAGCCAGTTGTACACTGGGGCAATTCTGCCGGAAAGTATCGTTATTTTGACCCTCAT
CGTTGTCTTGGTGGGGGATTTAATTGTCGGACGCGCCCGTTCGGGTTGGATTCCCTACGCGGCGATCGCCGGACTGTTGG
GGTCAGTATTCGCCTTGTACCTCGGTTGGGATAATCCCCATCCCGTTGCCTTTTTGGGGGCATTTAACAGCGATAACCTC
AGTATTTTATTCCGGGGCATCATTGTCCTGTCTACGGCCTTCACGATCATGATGTCGGTGCGCTATGTGGAACGTTCCGG
CACCGCCCTCTCTGAATTTATCTGCATCTTGCTCACGGCCACCCTGGGGGGGATGTTCCTCTCTGGGGCGAATGAGTTGG
TGATGATTTTTGTCTCCCTCGAAATGCTTAGTATCTCGTCTTATCTACTGACGGGCTACATGAAGCGAGACCCCCGTTCC
AATGAGGCCGCCCTCAAGTATTTGTTAATTGGGGCCGCGAGTTCGGCGATTTTCCTCTACGGTGTGTCTTTGCTCTATGG
CCTATCGGGTGGCAAGACAATTCTCAGTGAGATTGCCCTTGGATTTACGGATCCCCAGGGGGGCCAGTCCCTGGCGTTGG
CGATCGCCCTGGTCTTTGCGATCGCCGGGATCGCCTTCAAGATTTCCGCTGTGCCCTTCCACCAATGGACCCCTGACGTT
TACGAAGGTTCGCCTACCCCCGTTGTTGCGTTTCTCTCGGTGGGTTCTAAGGCCGCTGGTTTCGCCCTGGCGATCCGTTT
GTTGGTAACGGTCTTTAACCCCGTGAGCGAAGAATGGCACTTCATTTTCACAGCTTTGGCAATCCTCAGTATGGTCTTGG
GGAACGTGGTGGCTCTGGCGCAAACCAGCATGAAGCGGATGTTGGCCTATTCTTCCATTGCCCAGGCGGGTTTTGTGATG
ATTGGCCTCGTTGCGGGGACTGATGCGGGCTATTCCAGCGTAATTTTCTATCTGCTGGTGTATTTGTTCATGAACCTCGG
TGCATTTACCTGTGTGATTCTTTTCTCTCTCCGGACGGGCACAGACCAAATCGCGGAGTACGCAGGACTTTACCAAAAAG
ATCCGTTACTAACCCTCGGCCTTAGTGTTTGCCTACTCTCCCTTGGGGGCATTCCGCCATTAGCTGGGTTCTTCGGGAAA
ATTTATCTGTTCTGGGCTGGCTGGCAAGCGGGCCTCTATGGCTTAGTGCTGCTGGGTTTGATCACCAGTGTAATTTCAAT
CTACTACTACATCCGTGTGATCAAGATGATGGTGGTCAAGGAACCCCAGGAAATGTCTGATTCTGTGCGCAATTATCCAG
CGGTCACTTGGACGGCTGTGGGGATGAAACCTTTACAAGTGGGTCTGGTACTGTCGGTGATTATCACGTCTTTGGCGGGA
ATTCTCTCGAATCCGTTGTTTGTGATTGCGGATCAATCTGTCACCAGTACACCGATGTTGCAGGTGGCAAATCATCCCAC
AGAACAGGTCGTTGCCCAAGTAGACAGCGAGCTGGTTGGAGTGGCGATCGCCGATCACTAA

Upstream 100 bases:

>100_bases
CGACTGAGATCTAGAGGCCATTGCTGTCGAATCAGGAAACTCTGCCCGTTTGTGGTGGGGTAGTTCACTGGAAGTTGGTT
CACTAAGCCGAAGAGCAAAG

Downstream 100 bases:

>100_bases
GCAACGGTAAAACAATATTTTCAGTTCAAGATGATGACCCTCTGCCGCAATTGGTAGGGGGTTTTGATTAGCATGGGAGC
AGAGTTCGACTGAGCAAACG

Product: NAD(P)H-quinone oxidoreductase subunit 2

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit 2; NADH-plastoquinone oxidoreductase subunit 2; NDH-1, subunit 2

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALYLGWDNPHPVAFLGAFNSDNL
SILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTATLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRS
NEAALKYLLIGAASSAIFLYGVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDV
YEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALAQTSMKRMLAYSSIAQAGFVM
IGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTGTDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGK
IYLFWAGWQAGLYGLVLLGLITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAG
ILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH

Sequences:

>Translated_526_residues
MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALYLGWDNPHPVAFLGAFNSDNL
SILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTATLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRS
NEAALKYLLIGAASSAIFLYGVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDV
YEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALAQTSMKRMLAYSSIAQAGFVM
IGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTGTDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGK
IYLFWAGWQAGLYGLVLLGLITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAG
ILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH
>Mature_526_residues
MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALYLGWDNPHPVAFLGAFNSDNL
SILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTATLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRS
NEAALKYLLIGAASSAIFLYGVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDV
YEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALAQTSMKRMLAYSSIAQAGFVM
IGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTGTDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGK
IYLFWAGWQAGLYGLVLLGLITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAG
ILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831117, Length=391, Percent_Identity=24.2966751918159, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI145693160, Length=385, Percent_Identity=37.4025974025974, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1788614, Length=395, Percent_Identity=25.5696202531646, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788831, Length=284, Percent_Identity=26.056338028169, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788829, Length=354, Percent_Identity=26.8361581920904, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788613, Length=347, Percent_Identity=26.8011527377522, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788827, Length=331, Percent_Identity=25.6797583081571, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU2C_SYNP2 (Q8KX56)

Other databases:

- EMBL:   AF381035
- EMBL:   CP000951
- RefSeq:   YP_001735779.1
- GeneID:   6057832
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A2547
- HOGENOM:   HBG747830
- OMA:   FAGWADH
- ProtClustDB:   PRK02504
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: 1.6.5.3

Molecular weight: Translated: 56149; Mature: 56149

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d8b3f60)-; HASH(0x1e16039c)-; HASH(0x1e7fbd60)-; HASH(0x1e5480ec)-; HASH(0x1c973b14)-; HASH(0x1e951c28)-; HASH(0x1db60e88)-; HASH(0x1e548ffc)-; HASH(0x1b214d10)-; HASH(0x1e6d3f38)-; HASH(0x1e9a99ec)-; HASH(0x1e71bfa4)-; HASH(0x1eaefc5c)-; HASH(0x1dd96064)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALY
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LGWDNPHPVAFLGAFNSDNLSILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTA
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRSNEAALKYLLIGAASSAIFLY
HHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
GVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDV
HHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
YEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALA
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QTSMKRMLAYSSIAQAGFVMIGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTG
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYGLVLLGL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHHHHHHH
ITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH
HHCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHCCHHEEEEEECH
>Mature Secondary Structure
MDFSSTVASQLYTGAILPESIVILTLIVVLVGDLIVGRARSGWIPYAAIAGLLGSVFALY
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LGWDNPHPVAFLGAFNSDNLSILFRGIIVLSTAFTIMMSVRYVERSGTALSEFICILLTA
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLGGMFLSGANELVMIFVSLEMLSISSYLLTGYMKRDPRSNEAALKYLLIGAASSAIFLY
HHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
GVSLLYGLSGGKTILSEIALGFTDPQGGQSLALAIALVFAIAGIAFKISAVPFHQWTPDV
HHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
YEGSPTPVVAFLSVGSKAAGFALAIRLLVTVFNPVSEEWHFIFTALAILSMVLGNVVALA
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QTSMKRMLAYSSIAQAGFVMIGLVAGTDAGYSSVIFYLLVYLFMNLGAFTCVILFSLRTG
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDQIAEYAGLYQKDPLLTLGLSVCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYGLVLLGL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHHHHHHH
ITSVISIYYYIRVIKMMVVKEPQEMSDSVRNYPAVTWTAVGMKPLQVGLVLSVIITSLAG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ILSNPLFVIADQSVTSTPMLQVANHPTEQVVAQVDSELVGVAIADH
HHCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHCCHHEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA