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The map label for this gene is phoP [H]

Identifier: 170079118

GI number: 170079118

Start: 2631592

End: 2632272

Strand: Direct

Name: phoP [H]

Synonym: SYNPCC7002_A2523

Alternate gene names: 170079118

Gene position: 2631592-2632272 (Clockwise)

Preceding gene: 170079117

Following gene: 170079119

Centisome position: 87.49

GC content: 49.78

Gene sequence:

>681_bases
TTGGCTAACCCTGATCTTTGCGACCCTATTCCTGCCATGAGCGATTTTCCTAATCCCCAAGGTACGACTCTACTCCTAAT
TGACGACGATCCCAATCTCATTTTGTTAGTGCGCGATTATCTCGAATTTCGCGGCTATGACATGTTGACCGCGGCCAATG
GTGTCGAAGGCCTGCAAATCCTCGAAGAGACAACCCCTGACTTAATCATTTGTGATGTGATGATGCCAGAAATGGATGGT
TATACCTTTATCCAAAATGTCCGTCAAAATTCGCAAATTAGCTGGATCCCTGTAATTTTCCTCTCGGCAAAAGGGCAAAC
CTGCGATCGCATCGAGGGCCTGAACCAAGGGGCGGATGTGTACCTTGTGAAGCCTTTTGAACCAGAAGAATTAGTCGCCC
AGGTGGAGTCGTCGTTAAACCAGGCTCGGCGTATCCTGAGTCATTCTGGGGCGACAACCTCGTCCATGGCCTTTCAGGTG
CCGAGTCATGTGGAGCTTACCCCCACGGAAACTAAGGTTGTGAGCTTTGTGGCCCAGGGACTTTCTAACCGGGAAATTGC
CGAGAAGCTCAATGTAAGCCAGCGCACCATCGAAAGTCATGTGTCGAATATGTTGAACAAAACCAGCTTAAATAACCGCA
CGGAACTGGCGCGGTGGGCCATGGACAGTCGATTGGTGTAA

Upstream 100 bases:

>100_bases
CGTCCAGGATTATGTATTTATGGCCCACCCCCTACCCAAACCATCACCAGTAAACCCCGTCCCAAATCCCTAATCCCAGC
CAAAATTCCTTTGCTAAGAT

Downstream 100 bases:

>100_bases
AAGGCTTGACAATTTCCGGTGCGCTTTTGCTATACTTGCATACGGTTTAGAGACCAATGCCCACGTAGCTCAGTTGGTAG
AGCAGCTGATTTGTAATCAG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MANPDLCDPIPAMSDFPNPQGTTLLLIDDDPNLILLVRDYLEFRGYDMLTAANGVEGLQILEETTPDLIICDVMMPEMDG
YTFIQNVRQNSQISWIPVIFLSAKGQTCDRIEGLNQGADVYLVKPFEPEELVAQVESSLNQARRILSHSGATTSSMAFQV
PSHVELTPTETKVVSFVAQGLSNREIAEKLNVSQRTIESHVSNMLNKTSLNNRTELARWAMDSRLV

Sequences:

>Translated_226_residues
MANPDLCDPIPAMSDFPNPQGTTLLLIDDDPNLILLVRDYLEFRGYDMLTAANGVEGLQILEETTPDLIICDVMMPEMDG
YTFIQNVRQNSQISWIPVIFLSAKGQTCDRIEGLNQGADVYLVKPFEPEELVAQVESSLNQARRILSHSGATTSSMAFQV
PSHVELTPTETKVVSFVAQGLSNREIAEKLNVSQRTIESHVSNMLNKTSLNNRTELARWAMDSRLV
>Mature_225_residues
ANPDLCDPIPAMSDFPNPQGTTLLLIDDDPNLILLVRDYLEFRGYDMLTAANGVEGLQILEETTPDLIICDVMMPEMDGY
TFIQNVRQNSQISWIPVIFLSAKGQTCDRIEGLNQGADVYLVKPFEPEELVAQVESSLNQARRILSHSGATTSSMAFQVP
SHVELTPTETKVVSFVAQGLSNREIAEKLNVSQRTIESHVSNMLNKTSLNNRTELARWAMDSRLV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=214, Percent_Identity=31.3084112149533, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786599, Length=203, Percent_Identity=30.5418719211823, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI2367329, Length=208, Percent_Identity=32.6923076923077, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=36.1344537815126, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787473, Length=222, Percent_Identity=33.7837837837838, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082012, Length=161, Percent_Identity=34.1614906832298, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786911, Length=171, Percent_Identity=32.7485380116959, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788905, Length=119, Percent_Identity=36.1344537815126, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=27.9411764705882, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786747, Length=161, Percent_Identity=29.1925465838509, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.9672131147541, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786784, Length=150, Percent_Identity=28.6666666666667, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=28.7081339712919, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789402, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=30.327868852459, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790552, Length=204, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790860, Length=157, Percent_Identity=26.7515923566879, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=29.3103448275862, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=127, Percent_Identity=34.6456692913386, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787487, Length=107, Percent_Identity=30.8411214953271, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787375, Length=142, Percent_Identity=28.8732394366197, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25157; Mature: 25026

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPDLCDPIPAMSDFPNPQGTTLLLIDDDPNLILLVRDYLEFRGYDMLTAANGVEGLQI
CCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCEEEECCCCCHHHHH
LEETTPDLIICDVMMPEMDGYTFIQNVRQNSQISWIPVIFLSAKGQTCDRIEGLNQGADV
HHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCE
YLVKPFEPEELVAQVESSLNQARRILSHSGATTSSMAFQVPSHVELTPTETKVVSFVAQG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHC
LSNREIAEKLNVSQRTIESHVSNMLNKTSLNNRTELARWAMDSRLV
CCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANPDLCDPIPAMSDFPNPQGTTLLLIDDDPNLILLVRDYLEFRGYDMLTAANGVEGLQI
CCCCCCCCCCCHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCEEEECCCCCHHHHH
LEETTPDLIICDVMMPEMDGYTFIQNVRQNSQISWIPVIFLSAKGQTCDRIEGLNQGADV
HHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCE
YLVKPFEPEELVAQVESSLNQARRILSHSGATTSSMAFQVPSHVELTPTETKVVSFVAQG
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHC
LSNREIAEKLNVSQRTIESHVSNMLNKTSLNNRTELARWAMDSRLV
CCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]