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The map label for this gene is pqqL [C]

Identifier: 170079089

GI number: 170079089

Start: 2598868

End: 2600160

Strand: Direct

Name: pqqL [C]

Synonym: SYNPCC7002_A2494

Alternate gene names: 170079089

Gene position: 2598868-2600160 (Clockwise)

Preceding gene: 170079086

Following gene: 170079090

Centisome position: 86.4

GC content: 50.66

Gene sequence:

>1293_bases
ATGATGGGGGTAAGTTTCGCTTCGGTTATCCCCTTGCCCTACTCTCTCCAACCCGATCCGGTGCAATTGTTTACGCTCCC
CAATGGCCTCCAGGTGGTGCATCAATATTTGCCAGGGACGCCTGTGGTGGTCACCGATGTATGGGTTAAAGCAGGGGCGA
TCGCCGAACCGACAGAATGGGAAGGAATGGCCCATTTTTTAGAGCACATGATCTTTAAGGGATCGCACCAAGTCTGTCCC
GGTGAGTTTGATCAAATTGTTGAAACTTGCGGTGGGCTGAGTAATGCCGCCACCAGTTACGATTACGCCCATTTCTACCT
CAGTACTACGGGCGATCGCCTACCAGAAACTCTCCCTTATCTGAGCGATATTTTACGCAATGCCACCATTCCCGACGCCG
AATTTATCCGGGAACGCCAGGTAGTACTCGAAGAAATTAGTATTAGCCAAGATGACCCCGACTGGCTCGCTTTCCAAGCC
TTGAGCCGTCTCCTGTACGAAAATCACCCCTATGGCCGCTCGATTTTGGGCAATGCCGAACAACTGTGTGGCTATACCCC
CAACCAAATGCGCTGTTTTCACCGGACCCATTATCAACCCCAAAATTTAATCATCAGTATGGTTGGTAATATTCAAGTCG
ACCAGGCCCTAGATCTGATCCAAACCAACTTTAGTGATTTTCAGGTGCCTTCTGAATGTCCCCCCTTTGAGGTGGAGGCA
GAACCCCCCCTGATCGAGATTCGCCGCGATGAAATTCAAATGCCCAATGTGCAAATGGCCCGCTTAATCTTCGGTTGGCT
GGGGACAGGGGTTGAGCAATTTAATGATGCGGTGGGTCTGGATCTCCTGTCAGTGATCTTGGCCGGGACAACTTCCGCTT
GGCTGGTGCAAGAATTGCGGGAAAAACGTCAGTGGGTTTTGGATATTAATAGTGGTTTCTCTTTGCAACGGGACTCTAGT
TTATTTACGATCCAGGCCTGGCTCGATGCAGAACATTTAGACGATGTAGAACAGGTGATTGGCGATCGCCTTGCTGATCT
CCAGACCTGTTGTGTGAGCGAAGAAGAACTGCGTCGGGCGAAACGCATGCTGTGTAATGAGCACATTTTTTCGACGGAAA
GCGCGAGTCAGTTGGCCGGGCTCTACGGCTATTACCAAACCCTCGGCAGCCTTGATTATGCCCACCACTATCCCCAGATG
GTGGAAACCTTCACGATTGAGTCGCTCCAGCGTTTAGTGCGACAGTATCTTTCCCCGGAACACTACGGTATCGTCACTTT
AACCGGTACTTAA

Upstream 100 bases:

>100_bases
TAATAATGTCTGCTTAACTAAAGCCTGTATCGGGGCGTCGCAAAAAAAGTTGTTGTTTAGCTAAGTTCATGTTCCTTTAA
GCCCCAGAAAAGAAGCGGTT

Downstream 100 bases:

>100_bases
ATGGCACAACTCGCAACGGCAGAAAACGGCTGGGTGGATACAACTAAGGCCACCGATCCAGAGGCGATCGCCCTCGTCAA
AGATTTACTCGACACGCAGA

Product: processing proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMGVSFASVIPLPYSLQPDPVQLFTLPNGLQVVHQYLPGTPVVVTDVWVKAGAIAEPTEWEGMAHFLEHMIFKGSHQVCP
GEFDQIVETCGGLSNAATSYDYAHFYLSTTGDRLPETLPYLSDILRNATIPDAEFIRERQVVLEEISISQDDPDWLAFQA
LSRLLYENHPYGRSILGNAEQLCGYTPNQMRCFHRTHYQPQNLIISMVGNIQVDQALDLIQTNFSDFQVPSECPPFEVEA
EPPLIEIRRDEIQMPNVQMARLIFGWLGTGVEQFNDAVGLDLLSVILAGTTSAWLVQELREKRQWVLDINSGFSLQRDSS
LFTIQAWLDAEHLDDVEQVIGDRLADLQTCCVSEEELRRAKRMLCNEHIFSTESASQLAGLYGYYQTLGSLDYAHHYPQM
VETFTIESLQRLVRQYLSPEHYGIVTLTGT

Sequences:

>Translated_430_residues
MMGVSFASVIPLPYSLQPDPVQLFTLPNGLQVVHQYLPGTPVVVTDVWVKAGAIAEPTEWEGMAHFLEHMIFKGSHQVCP
GEFDQIVETCGGLSNAATSYDYAHFYLSTTGDRLPETLPYLSDILRNATIPDAEFIRERQVVLEEISISQDDPDWLAFQA
LSRLLYENHPYGRSILGNAEQLCGYTPNQMRCFHRTHYQPQNLIISMVGNIQVDQALDLIQTNFSDFQVPSECPPFEVEA
EPPLIEIRRDEIQMPNVQMARLIFGWLGTGVEQFNDAVGLDLLSVILAGTTSAWLVQELREKRQWVLDINSGFSLQRDSS
LFTIQAWLDAEHLDDVEQVIGDRLADLQTCCVSEEELRRAKRMLCNEHIFSTESASQLAGLYGYYQTLGSLDYAHHYPQM
VETFTIESLQRLVRQYLSPEHYGIVTLTGT
>Mature_430_residues
MMGVSFASVIPLPYSLQPDPVQLFTLPNGLQVVHQYLPGTPVVVTDVWVKAGAIAEPTEWEGMAHFLEHMIFKGSHQVCP
GEFDQIVETCGGLSNAATSYDYAHFYLSTTGDRLPETLPYLSDILRNATIPDAEFIRERQVVLEEISISQDDPDWLAFQA
LSRLLYENHPYGRSILGNAEQLCGYTPNQMRCFHRTHYQPQNLIISMVGNIQVDQALDLIQTNFSDFQVPSECPPFEVEA
EPPLIEIRRDEIQMPNVQMARLIFGWLGTGVEQFNDAVGLDLLSVILAGTTSAWLVQELREKRQWVLDINSGFSLQRDSS
LFTIQAWLDAEHLDDVEQVIGDRLADLQTCCVSEEELRRAKRMLCNEHIFSTESASQLAGLYGYYQTLGSLDYAHHYPQM
VETFTIESLQRLVRQYLSPEHYGIVTLTGT

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=253, Percent_Identity=29.2490118577075, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI46593007, Length=253, Percent_Identity=24.5059288537549, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1787770, Length=225, Percent_Identity=31.1111111111111, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367164, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=227, Percent_Identity=26.8722466960352, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17553678, Length=390, Percent_Identity=23.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72001443, Length=337, Percent_Identity=22.2551928783383, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994338, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25146563, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=210, Percent_Identity=29.0476190476191, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324474, Length=324, Percent_Identity=26.2345679012346, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323421, Length=345, Percent_Identity=22.0289855072464, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=265, Percent_Identity=26.7924528301887, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646943, Length=265, Percent_Identity=26.7924528301887, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641429, Length=320, Percent_Identity=25.9375, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667786, Length=168, Percent_Identity=29.7619047619048, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221513245, Length=334, Percent_Identity=22.4550898203593, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48627; Mature: 48627

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGVSFASVIPLPYSLQPDPVQLFTLPNGLQVVHQYLPGTPVVVTDVWVKAGAIAEPTEW
CCCCCCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCH
EGMAHFLEHMIFKGSHQVCPGEFDQIVETCGGLSNAATSYDYAHFYLSTTGDRLPETLPY
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCCHHHHHH
LSDILRNATIPDAEFIRERQVVLEEISISQDDPDWLAFQALSRLLYENHPYGRSILGNAE
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCHH
QLCGYTPNQMRCFHRTHYQPQNLIISMVGNIQVDQALDLIQTNFSDFQVPSECPPFEVEA
HHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPPLIEIRRDEIQMPNVQMARLIFGWLGTGVEQFNDAVGLDLLSVILAGTTSAWLVQELR
CCCEEEEEHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EKRQWVLDINSGFSLQRDSSLFTIQAWLDAEHLDDVEQVIGDRLADLQTCCVSEEELRRA
HHCCEEEECCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KRMLCNEHIFSTESASQLAGLYGYYQTLGSLDYAHHYPQMVETFTIESLQRLVRQYLSPE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYGIVTLTGT
CCEEEEEECC
>Mature Secondary Structure
MMGVSFASVIPLPYSLQPDPVQLFTLPNGLQVVHQYLPGTPVVVTDVWVKAGAIAEPTEW
CCCCCCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCH
EGMAHFLEHMIFKGSHQVCPGEFDQIVETCGGLSNAATSYDYAHFYLSTTGDRLPETLPY
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCCHHHHHH
LSDILRNATIPDAEFIRERQVVLEEISISQDDPDWLAFQALSRLLYENHPYGRSILGNAE
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCHH
QLCGYTPNQMRCFHRTHYQPQNLIISMVGNIQVDQALDLIQTNFSDFQVPSECPPFEVEA
HHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPPLIEIRRDEIQMPNVQMARLIFGWLGTGVEQFNDAVGLDLLSVILAGTTSAWLVQELR
CCCEEEEEHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EKRQWVLDINSGFSLQRDSSLFTIQAWLDAEHLDDVEQVIGDRLADLQTCCVSEEELRRA
HHCCEEEECCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KRMLCNEHIFSTESASQLAGLYGYYQTLGSLDYAHHYPQMVETFTIESLQRLVRQYLSPE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HYGIVTLTGT
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]