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The map label for this gene is argH [H]

Identifier: 170079082

GI number: 170079082

Start: 2588869

End: 2590260

Strand: Reverse

Name: argH [H]

Synonym: SYNPCC7002_A2487

Alternate gene names: 170079082

Gene position: 2590260-2588869 (Counterclockwise)

Preceding gene: 170079085

Following gene: 170079075

Centisome position: 86.11

GC content: 49.93

Gene sequence:

>1392_bases
ATGACAGAAGCTAAAAAAACCTGGAGCGATCGCTTTGATACATCGCTACATCCGGCGATCGCCGTGTTTAATGCCAGTAT
CGGCTTTGATATTGAACTGATCGAGTATGACATTACGGGTTCAGTGGCCCATGCCCAGATGCTCGCCCACACTGGGATTA
TTTCCGCCGAAGAAGGTAAAATCCTCGTCCAAGGTTTAGAACAAGTCCGCCAGGAATATCGCAAGGGCAACTTTCACCCC
GGCGTCGAAGATGAGGATGTCCATTTCGCAGTCGAAAAACGCTTGACGGCAATTGTTGGCGATGTGGGCAAAAAACTCCA
CACCGGGCGATCGCGCAATGATCAGGTAGGCACGGATATTCGTCTCTATCTGCGGGACAAAATTCGCGGCATTCAGCAGC
AATTGCGAGACTTTCAACAGGTTTTATTGAATCACGCGGAAAACCATGTGGAGACTTTGATTCCCGGCTATACCCACCTG
CAACGGGCGCAACCAATTAGCCTCGCCCATCACTTGATGGCCTATTTCCAGATGGCCCAACGGGATTATGAACGGTTGGA
TGATGTCTACAAGCGCACCAATACTTCTCCCCTTGGTTGTGGCGCTTTGGCGGGGACAACTTTTCCCATTGATCGCCATT
TCAGCGCGAATTTACTCGGCTTTGAACGCCTCTATCAAAACAGTCTCGATGGGGTCAGCGATCGCGATTTTGCCATCGAG
TTTTCCGCCGCTGCCAGCTTGATCATGGTGCACCTGAGCCGCTTGTCTGAAGAGATGATTTTCTGGGCCTCGAAGGAATT
TAGTTTTATTAGCTTAAAAGATAGTTGTGCGACGGGTTCGAGCATTATGCCCCAGAAGAAAAACCCGGATATTCCGGAAT
TGGTGCGCGGCAAAACAGGTCGCGTGTTTGGACATCTCCAAGGGTTACTCGTGCTGATGAAAGGCTTACCCCTCGCCTAT
AATAAGGATTTGCAAGACGATAAAGAGGGCCTTTTTGATACCGTTAAAACAGTGCAGGGTTGCCTCGAAGCGATGACCAT
TTTGCTCGGTGAGGGGATTGAATTCCGCACCCAACGCCTTGAGGAAGCAGTAAACGAAGACTTTTCTAACGCGACCGATG
TGGCTGATTATTTAGCGAGTAAAGGGGTGCCGTTCCGGGAAGCCTATAACCTCGTGGGCAAAGTAGTGAAAACCAGTCTT
GCCGCTGACAAATTGCTCAAGGATTTGACGATGGACGAATGGAAAGCATTACATCCTGCCTTTGAAGAAGATATCTATCA
GGCGATCGCCCCCCAGCAAGTCGTGGCAGCCCGTAATAGTTATGGAGGCACAGGTTTTGAACAGGTACGGCAGGCGATCG
CTGAAGCCCAAAATCTTCTGACCAATCCCTAG

Upstream 100 bases:

>100_bases
CTCACCGCTTTGGGGAAGATCGGCGTTTAGGGGAATGGCTTGATGCCGTAAGATTTACCGAGAGAATTGATTGTGATTTC
CTGCGAGGGCTAGTGCCGTT

Downstream 100 bases:

>100_bases
CATTTCGCTGGAGGGGGTATCGAGAAGATACTTTCTTTGTAATGGATAGTGGCGATCGTTATTGCACTAATGATTTGTTA
GCGAGCTATAGTGTTTCCTC

Product: argininosuccinate lyase

Products: NA

Alternate protein names: ASAL; Arginosuccinase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTEAKKTWSDRFDTSLHPAIAVFNASIGFDIELIEYDITGSVAHAQMLAHTGIISAEEGKILVQGLEQVRQEYRKGNFHP
GVEDEDVHFAVEKRLTAIVGDVGKKLHTGRSRNDQVGTDIRLYLRDKIRGIQQQLRDFQQVLLNHAENHVETLIPGYTHL
QRAQPISLAHHLMAYFQMAQRDYERLDDVYKRTNTSPLGCGALAGTTFPIDRHFSANLLGFERLYQNSLDGVSDRDFAIE
FSAAASLIMVHLSRLSEEMIFWASKEFSFISLKDSCATGSSIMPQKKNPDIPELVRGKTGRVFGHLQGLLVLMKGLPLAY
NKDLQDDKEGLFDTVKTVQGCLEAMTILLGEGIEFRTQRLEEAVNEDFSNATDVADYLASKGVPFREAYNLVGKVVKTSL
AADKLLKDLTMDEWKALHPAFEEDIYQAIAPQQVVAARNSYGGTGFEQVRQAIAEAQNLLTNP

Sequences:

>Translated_463_residues
MTEAKKTWSDRFDTSLHPAIAVFNASIGFDIELIEYDITGSVAHAQMLAHTGIISAEEGKILVQGLEQVRQEYRKGNFHP
GVEDEDVHFAVEKRLTAIVGDVGKKLHTGRSRNDQVGTDIRLYLRDKIRGIQQQLRDFQQVLLNHAENHVETLIPGYTHL
QRAQPISLAHHLMAYFQMAQRDYERLDDVYKRTNTSPLGCGALAGTTFPIDRHFSANLLGFERLYQNSLDGVSDRDFAIE
FSAAASLIMVHLSRLSEEMIFWASKEFSFISLKDSCATGSSIMPQKKNPDIPELVRGKTGRVFGHLQGLLVLMKGLPLAY
NKDLQDDKEGLFDTVKTVQGCLEAMTILLGEGIEFRTQRLEEAVNEDFSNATDVADYLASKGVPFREAYNLVGKVVKTSL
AADKLLKDLTMDEWKALHPAFEEDIYQAIAPQQVVAARNSYGGTGFEQVRQAIAEAQNLLTNP
>Mature_462_residues
TEAKKTWSDRFDTSLHPAIAVFNASIGFDIELIEYDITGSVAHAQMLAHTGIISAEEGKILVQGLEQVRQEYRKGNFHPG
VEDEDVHFAVEKRLTAIVGDVGKKLHTGRSRNDQVGTDIRLYLRDKIRGIQQQLRDFQQVLLNHAENHVETLIPGYTHLQ
RAQPISLAHHLMAYFQMAQRDYERLDDVYKRTNTSPLGCGALAGTTFPIDRHFSANLLGFERLYQNSLDGVSDRDFAIEF
SAAASLIMVHLSRLSEEMIFWASKEFSFISLKDSCATGSSIMPQKKNPDIPELVRGKTGRVFGHLQGLLVLMKGLPLAYN
KDLQDDKEGLFDTVKTVQGCLEAMTILLGEGIEFRTQRLEEAVNEDFSNATDVADYLASKGVPFREAYNLVGKVVKTSLA
ADKLLKDLTMDEWKALHPAFEEDIYQAIAPQQVVAARNSYGGTGFEQVRQAIAEAQNLLTNP

Specific function: Arginine biosynthesis; eighth (last) step. [C]

COG id: COG0165

COG function: function code E; Argininosuccinate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily [H]

Homologues:

Organism=Homo sapiens, GI31541964, Length=459, Percent_Identity=40.958605664488, Blast_Score=358, Evalue=5e-99,
Organism=Homo sapiens, GI68303542, Length=459, Percent_Identity=40.958605664488, Blast_Score=358, Evalue=5e-99,
Organism=Homo sapiens, GI68303549, Length=459, Percent_Identity=38.3442265795207, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI68303547, Length=459, Percent_Identity=38.1263616557734, Blast_Score=320, Evalue=1e-87,
Organism=Escherichia coli, GI1790398, Length=454, Percent_Identity=46.4757709251101, Blast_Score=410, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321806, Length=449, Percent_Identity=41.4253897550111, Blast_Score=349, Evalue=6e-97,
Organism=Drosophila melanogaster, GI221473854, Length=449, Percent_Identity=39.6436525612472, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI78706858, Length=449, Percent_Identity=39.6436525612472, Blast_Score=322, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009049
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761 [H]

Pfam domain/function: PF00206 Lyase_1 [H]

EC number: =4.3.2.1 [H]

Molecular weight: Translated: 51746; Mature: 51615

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAKKTWSDRFDTSLHPAIAVFNASIGFDIELIEYDITGSVAHAQMLAHTGIISAEEGK
CCCCHHHHHHHCCCCCCHHHHHEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCH
ILVQGLEQVRQEYRKGNFHPGVEDEDVHFAVEKRLTAIVGDVGKKLHTGRSRNDQVGTDI
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RLYLRDKIRGIQQQLRDFQQVLLNHAENHVETLIPGYTHLQRAQPISLAHHLMAYFQMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
RDYERLDDVYKRTNTSPLGCGALAGTTFPIDRHFSANLLGFERLYQNSLDGVSDRDFAIE
HHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
FSAAASLIMVHLSRLSEEMIFWASKEFSFISLKDSCATGSSIMPQKKNPDIPELVRGKTG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCC
RVFGHLQGLLVLMKGLPLAYNKDLQDDKEGLFDTVKTVQGCLEAMTILLGEGIEFRTQRL
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EEAVNEDFSNATDVADYLASKGVPFREAYNLVGKVVKTSLAADKLLKDLTMDEWKALHPA
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
FEEDIYQAIAPQQVVAARNSYGGTGFEQVRQAIAEAQNLLTNP
HHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEAKKTWSDRFDTSLHPAIAVFNASIGFDIELIEYDITGSVAHAQMLAHTGIISAEEGK
CCCHHHHHHHCCCCCCHHHHHEECCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCH
ILVQGLEQVRQEYRKGNFHPGVEDEDVHFAVEKRLTAIVGDVGKKLHTGRSRNDQVGTDI
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RLYLRDKIRGIQQQLRDFQQVLLNHAENHVETLIPGYTHLQRAQPISLAHHLMAYFQMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
RDYERLDDVYKRTNTSPLGCGALAGTTFPIDRHFSANLLGFERLYQNSLDGVSDRDFAIE
HHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
FSAAASLIMVHLSRLSEEMIFWASKEFSFISLKDSCATGSSIMPQKKNPDIPELVRGKTG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCC
RVFGHLQGLLVLMKGLPLAYNKDLQDDKEGLFDTVKTVQGCLEAMTILLGEGIEFRTQRL
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EEAVNEDFSNATDVADYLASKGVPFREAYNLVGKVVKTSLAADKLLKDLTMDEWKALHPA
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
FEEDIYQAIAPQQVVAARNSYGGTGFEQVRQAIAEAQNLLTNP
HHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA