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The map label for this gene is asnC

Identifier: 170079063

GI number: 170079063

Start: 2571857

End: 2573239

Strand: Direct

Name: asnC

Synonym: SYNPCC7002_A2468

Alternate gene names: 170079063

Gene position: 2571857-2573239 (Clockwise)

Preceding gene: 170079062

Following gene: 170079066

Centisome position: 85.5

GC content: 50.69

Gene sequence:

>1383_bases
ATGCGCATTAAGGAAATCCTCAACACCGCCGCCATCAACAGCACCATCACCGCCGAGGGATGGGTCAAAACCAAACGGGA
ATTGAAGGGATTTTCTTTCATTGAAATTAGCGACGGCTCCACGATGAATGGCCTCCAAGTGATTATCGATGGCAATCTGG
CCGACTACGAAGCAATCATTAAAAAGCTCAATACAGGGGCTGCGGTTACAGCGACGGGGTTAGTGGTGGAATCCCCAGGT
AAAGGGCAACGCATCGAACTCCAGGCCAAAGCGGTGACTGTCCACGGGGAAGCAGATCCGGAAACCTATCCCCTCCAGAA
AAAACGCCATAGCTTCGAATTTTTGCGCACCATCGGCCACCTGCGCGGCAAAACCAACACCATGGGGGCAGTGATGCGGG
TGCGGAATGCCTGTGCCACCGCGATTCACCAATTTTTCCAGGAACGGGGCTTTATCTGGGCTCACACGCCGATTATTACT
GCCAGCGATTGCGAAGGGGCCGGGGAAATGTTTGCGGTCACCAATTTTGATCTGGCCAATCCGAAGCGGACAAAAGAGGG
AGCCGTTGACTATGCCGAAGACTTTTTTGGGCGACCTGCTTATCTCACCGTGAGCGGTCAGTTGGAAGCAGAAGTGATGG
CGATGGCTTTCAAAGATGTTTATACGTTTGGGCCGACCTTCCGGGCAGAAAACTCCAACACTTCCAGGCACTTGGCGGAG
TTTTGGATGGTCGAACCGGAAATGGCCTTTTGCGATATTGTCGGCGACCAGGATTTGGCCGAGGAATTTTTGCGCTACAT
CTTCAAGTATGTGTTGGAAGCTTGCCCTGAAGACATGGAATTTTTCAACAAGCGCATTGATAATTCTGTCCTCGCCACGG
CTCAAAATATTATCGAGAATGAGTTCGCCCGCATTACCTACACCGAGGCGATCGCCCTTTTAGAAAAAAGCAATAAAACC
TTTGAATTTCCAGTGGAATGGGGGATCGATCTCCAGTCAGAACATGAGCGTTATCTCGCCGAAGACCTATTTAAAAAGCC
CTTGATCGTGAGCAACTATCCAAAAGATATTAAGGCTTTTTATATGCGCCTCAATGATGACCAGAAAACCGTGGCGGCCA
TGGATGTGCTCGCGCCAAAAATTGGCGAAATTATTGGTGGCTCCCAACGGGAAGAACGGCTCGATGTGCTGGAACGACGC
ATTCAGGAGATGAACATCGAAGCAGCAGATCTGTGGTGGTATCTCGATCTACGGCGGTTTGGCACCGTCCCCCATGCGGG
CTTTGGTCTTGGTTTTGAAAGACTGGTGCAGTTTATGACCGGGATGGGCAATATCCGCGATGTGATTCCTTTCCCCCGTA
CCCCTCTAAATGCTGAGTTTTAA

Upstream 100 bases:

>100_bases
TGACGAAACCGTCCCCATTTCTGCCCTGAACCCCGCAAACTCGGTAAGATAAAGGGCGCACTTATTTTCAGTTCCTCTAC
CTCAGACTCGATCAACGACC

Downstream 100 bases:

>100_bases
GGTTTGTTCTTTAGTTTTGCGATTCACAAATGAATTCAATCAAGACATGTTGATCTTGTTGAAATTTCTGACATTGCTAA
AGTGCAGAATAGCAGGCGAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MRIKEILNTAAINSTITAEGWVKTKRELKGFSFIEISDGSTMNGLQVIIDGNLADYEAIIKKLNTGAAVTATGLVVESPG
KGQRIELQAKAVTVHGEADPETYPLQKKRHSFEFLRTIGHLRGKTNTMGAVMRVRNACATAIHQFFQERGFIWAHTPIIT
ASDCEGAGEMFAVTNFDLANPKRTKEGAVDYAEDFFGRPAYLTVSGQLEAEVMAMAFKDVYTFGPTFRAENSNTSRHLAE
FWMVEPEMAFCDIVGDQDLAEEFLRYIFKYVLEACPEDMEFFNKRIDNSVLATAQNIIENEFARITYTEAIALLEKSNKT
FEFPVEWGIDLQSEHERYLAEDLFKKPLIVSNYPKDIKAFYMRLNDDQKTVAAMDVLAPKIGEIIGGSQREERLDVLERR
IQEMNIEAADLWWYLDLRRFGTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPLNAEF

Sequences:

>Translated_460_residues
MRIKEILNTAAINSTITAEGWVKTKRELKGFSFIEISDGSTMNGLQVIIDGNLADYEAIIKKLNTGAAVTATGLVVESPG
KGQRIELQAKAVTVHGEADPETYPLQKKRHSFEFLRTIGHLRGKTNTMGAVMRVRNACATAIHQFFQERGFIWAHTPIIT
ASDCEGAGEMFAVTNFDLANPKRTKEGAVDYAEDFFGRPAYLTVSGQLEAEVMAMAFKDVYTFGPTFRAENSNTSRHLAE
FWMVEPEMAFCDIVGDQDLAEEFLRYIFKYVLEACPEDMEFFNKRIDNSVLATAQNIIENEFARITYTEAIALLEKSNKT
FEFPVEWGIDLQSEHERYLAEDLFKKPLIVSNYPKDIKAFYMRLNDDQKTVAAMDVLAPKIGEIIGGSQREERLDVLERR
IQEMNIEAADLWWYLDLRRFGTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPLNAEF
>Mature_460_residues
MRIKEILNTAAINSTITAEGWVKTKRELKGFSFIEISDGSTMNGLQVIIDGNLADYEAIIKKLNTGAAVTATGLVVESPG
KGQRIELQAKAVTVHGEADPETYPLQKKRHSFEFLRTIGHLRGKTNTMGAVMRVRNACATAIHQFFQERGFIWAHTPIIT
ASDCEGAGEMFAVTNFDLANPKRTKEGAVDYAEDFFGRPAYLTVSGQLEAEVMAMAFKDVYTFGPTFRAENSNTSRHLAE
FWMVEPEMAFCDIVGDQDLAEEFLRYIFKYVLEACPEDMEFFNKRIDNSVLATAQNIIENEFARITYTEAIALLEKSNKT
FEFPVEWGIDLQSEHERYLAEDLFKKPLIVSNYPKDIKAFYMRLNDDQKTVAAMDVLAPKIGEIIGGSQREERLDVLERR
IQEMNIEAADLWWYLDLRRFGTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPLNAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=445, Percent_Identity=44.9438202247191, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI4758762, Length=465, Percent_Identity=27.5268817204301, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=28.9473684210526, Blast_Score=122, Evalue=9e-28,
Organism=Escherichia coli, GI1787161, Length=452, Percent_Identity=58.4070796460177, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1790571, Length=472, Percent_Identity=23.9406779661017, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17556372, Length=439, Percent_Identity=31.6628701594533, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71984122, Length=464, Percent_Identity=28.448275862069, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=28.3625730994152, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319872, Length=469, Percent_Identity=36.8869936034115, Blast_Score=309, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6321807, Length=462, Percent_Identity=28.7878787878788, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=28.7790697674419, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922416, Length=458, Percent_Identity=33.8427947598253, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI19921528, Length=478, Percent_Identity=28.0334728033473, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17136276, Length=346, Percent_Identity=26.878612716763, Blast_Score=109, Evalue=5e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SYNP2 (B1XKH1)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001735701.1
- ProteinModelPortal:   B1XKH1
- SMR:   B1XKH1
- GeneID:   6057731
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A2468
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52048; Mature: 52048

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50862 AA_TRNA_LIGASE_II; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKEILNTAAINSTITAEGWVKTKRELKGFSFIEISDGSTMNGLQVIIDGNLADYEAII
CCHHHHHHHHHCCCCEECCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCHHHHHHH
KKLNTGAAVTATGLVVESPGKGQRIELQAKAVTVHGEADPETYPLQKKRHSFEFLRTIGH
HHHCCCCEEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LRGKTNTMGAVMRVRNACATAIHQFFQERGFIWAHTPIITASDCEGAGEMFAVTNFDLAN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEECCCCCC
PKRTKEGAVDYAEDFFGRPAYLTVSGQLEAEVMAMAFKDVYTFGPTFRAENSNTSRHLAE
CCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
FWMVEPEMAFCDIVGDQDLAEEFLRYIFKYVLEACPEDMEFFNKRIDNSVLATAQNIIEN
HHCCCCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHH
EFARITYTEAIALLEKSNKTFEFPVEWGIDLQSEHERYLAEDLFKKPLIVSNYPKDIKAF
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHH
YMRLNDDQKTVAAMDVLAPKIGEIIGGSQREERLDVLERRIQEMNIEAADLWWYLDLRRF
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEEHHHH
GTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPLNAEF
CCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRIKEILNTAAINSTITAEGWVKTKRELKGFSFIEISDGSTMNGLQVIIDGNLADYEAII
CCHHHHHHHHHCCCCEECCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCHHHHHHH
KKLNTGAAVTATGLVVESPGKGQRIELQAKAVTVHGEADPETYPLQKKRHSFEFLRTIGH
HHHCCCCEEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LRGKTNTMGAVMRVRNACATAIHQFFQERGFIWAHTPIITASDCEGAGEMFAVTNFDLAN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEECCCCCC
PKRTKEGAVDYAEDFFGRPAYLTVSGQLEAEVMAMAFKDVYTFGPTFRAENSNTSRHLAE
CCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
FWMVEPEMAFCDIVGDQDLAEEFLRYIFKYVLEACPEDMEFFNKRIDNSVLATAQNIIEN
HHCCCCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHH
EFARITYTEAIALLEKSNKTFEFPVEWGIDLQSEHERYLAEDLFKKPLIVSNYPKDIKAF
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHH
YMRLNDDQKTVAAMDVLAPKIGEIIGGSQREERLDVLERRIQEMNIEAADLWWYLDLRRF
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHEEEEEHHHH
GTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPLNAEF
CCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA