| Definition | Synechococcus sp. PCC 7002 chromosome, complete genome. |
|---|---|
| Accession | NC_010475 |
| Length | 3,008,047 |
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The map label for this gene is dnaE [H]
Identifier: 170078979
GI number: 170078979
Start: 2464765
End: 2466105
Strand: Reverse
Name: dnaE [H]
Synonym: SYNPCC7002_A2384
Alternate gene names: 170078979
Gene position: 2466105-2464765 (Counterclockwise)
Preceding gene: 170078981
Following gene: 170078978
Centisome position: 81.98
GC content: 48.77
Gene sequence:
>1341_bases TTGGTTAAAATCATTCGCCGTAAGTTCATTGGCCATGCGCCGACCTATGATATTGGACTCAGTCAAGACCATAATTTCTT ATTGGGTCAGGGCCTTATTGCGGCTAACTGTTTTAATAAATCCCACTCAACGGCCTATGCCTACGTCACCTACCAGACTG CTTACCTGAAGGCAAACTATCCCGTTGAATACATGACGGCACTGCTCAGTGCCAGCAGTGGAAATAAAGATAAAGTCCGC AAGTACCGGGAAAATGCCGAGCGCATGGGTATCCTGGTCTTGCCACCGGATATTAACGAGTCAGACCTGGATTTTAAGCC CGTAGGCCAAGGGATTCGTTTTGGTTTGTCAGCGGTTCAAAACCTTGGTGAAAATGCGATCAATGCCATTTTAGCGGCCC GGGAAGCGGGGCCTTTTTTAAGTTTGTCTGACCTCTGTTCTCGGTTAGATTTGCGTGTTGTGAACCGCCGCGCCCTAGAA ACTTTAATTACCTGTGGTGGACTGGATTCACTCCATGATAATCGCCAGGCAATGCTGAAGGGTCTGGATTTAATGATGGA TTGGGCACAGTTGAAAGCGAAAGAAAAGGCCAGTGGTCAAACGAATTTATTTGAAAGTCTGGGAGATACGGCAGCGGCAT TTGATGAGGCCCCTGTGTTACCCAAAGTGGCTGATTTAACCTTAGAAGAAAAGCTCCGGCAAGAAAAAGAATTGCTGGGA TTTTATGTTTCTGAGCACCCTTTAGAAAAGCTGCGGTCAACGATTTCGCCGATTTTATCGCCCATTAGCCTTACGGCGAT CGCCAATCACATCAATAAAAAAGTCAGCGCCGTGGCGATCCTCACGGATATGCGCAAGATTTTTACGAAGGCCAATAATG AGCCCATGGCCTTTATTCAATTAGAAGATATTTCGGGTCAAGTAGAAGGGATTGTCTTTCCCCGCACTTATCAGAAAGTT GAGCAACTCTTACAGCTTGATAGCCGTGTCATTGTGTGGGGCAAAGTGCAACAAAAAGAGGATCGAACGCAACTGATTGT GGACGATCTCGAACCCATTGAAGAGGTGCGAATGTTGATGATTCGCCTCTCTCCGAGTGAGCTTCATCACACCCAAAGTC AGCAGCGACTGAAGCAAATTTTGTCACAGCAGGCTGGGGATAAGAAGAAGCGGGGGCGGATCCCGGTGATCGTGATCGTT GGGAGGGGCGGCGATCGCACCTTTATTCGCCTTGGGCAAGACTATTGGGTCGAGGACGATCACCAGGCCCTCTTGGCACT CCGACAGGGGGGCTTCCATGTCTACCGCGAAAACCTGATTCCCCAGGCCCAAGCGAGCTAA
Upstream 100 bases:
>100_bases AGTGGGTCGCTGTCGGCTAAAAGTGTGCCAAGACAAAACTGAAAAATATGACTTTTTTTATATAGAATAGGGTTGATCTC GACCTAAGGTTCTCGCAGTT
Downstream 100 bases:
>100_bases CCATTACTTCTACTTTTTAAAAGAAACCCATAAAACCCATAAATCCTATGTCTTACACTTACGAATATCCAAAACCGAGC GTTACCGTTGACTGTGTTGT
Product: DNA polymerase III subunit alpha
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 446; Mature: 446
Protein sequence:
>446_residues MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLSASSGNKDKVR KYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQNLGENAINAILAAREAGPFLSLSDLCSRLDLRVVNRRALE TLITCGGLDSLHDNRQAMLKGLDLMMDWAQLKAKEKASGQTNLFESLGDTAAAFDEAPVLPKVADLTLEEKLRQEKELLG FYVSEHPLEKLRSTISPILSPISLTAIANHINKKVSAVAILTDMRKIFTKANNEPMAFIQLEDISGQVEGIVFPRTYQKV EQLLQLDSRVIVWGKVQQKEDRTQLIVDDLEPIEEVRMLMIRLSPSELHHTQSQQRLKQILSQQAGDKKKRGRIPVIVIV GRGGDRTFIRLGQDYWVEDDHQALLALRQGGFHVYRENLIPQAQAS
Sequences:
>Translated_446_residues MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLSASSGNKDKVR KYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQNLGENAINAILAAREAGPFLSLSDLCSRLDLRVVNRRALE TLITCGGLDSLHDNRQAMLKGLDLMMDWAQLKAKEKASGQTNLFESLGDTAAAFDEAPVLPKVADLTLEEKLRQEKELLG FYVSEHPLEKLRSTISPILSPISLTAIANHINKKVSAVAILTDMRKIFTKANNEPMAFIQLEDISGQVEGIVFPRTYQKV EQLLQLDSRVIVWGKVQQKEDRTQLIVDDLEPIEEVRMLMIRLSPSELHHTQSQQRLKQILSQQAGDKKKRGRIPVIVIV GRGGDRTFIRLGQDYWVEDDHQALLALRQGGFHVYRENLIPQAQAS >Mature_446_residues MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLSASSGNKDKVR KYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQNLGENAINAILAAREAGPFLSLSDLCSRLDLRVVNRRALE TLITCGGLDSLHDNRQAMLKGLDLMMDWAQLKAKEKASGQTNLFESLGDTAAAFDEAPVLPKVADLTLEEKLRQEKELLG FYVSEHPLEKLRSTISPILSPISLTAIANHINKKVSAVAILTDMRKIFTKANNEPMAFIQLEDISGQVEGIVFPRTYQKV EQLLQLDSRVIVWGKVQQKEDRTQLIVDDLEPIEEVRMLMIRLSPSELHHTQSQQRLKQILSQQAGDKKKRGRIPVIVIV GRGGDRTFIRLGQDYWVEDDHQALLALRQGGFHVYRENLIPQAQAS
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase [H]
COG id: COG0587
COG function: function code L; DNA polymerase III, alpha subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DNA polymerase type-C family. DnaE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786381, Length=408, Percent_Identity=32.843137254902, Blast_Score=179, Evalue=4e-46,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011708 - InterPro: IPR003587 - InterPro: IPR006141 - InterPro: IPR004365 - InterPro: IPR004013 - InterPro: IPR003141 - InterPro: IPR016195 - InterPro: IPR004805 [H]
Pfam domain/function: PF07733 DNA_pol3_alpha; PF02811 PHP; PF01336 tRNA_anti [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 50000; Mature: 50000
Theoretical pI: Translated: 8.42; Mature: 8.42
Prosite motif: PS50818 INTEIN_C_TER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANY CHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEHHCCCCCCCEEEEEEEEEEEEEECC PVEYMTALLSASSGNKDKVRKYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQ CHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHCCHHHHHHHHHHH NLGENAINAILAAREAGPFLSLSDLCSRLDLRVVNRRALETLITCGGLDSLHDNRQAMLK HHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHH GLDLMMDWAQLKAKEKASGQTNLFESLGDTAAAFDEAPVLPKVADLTLEEKLRQEKELLG HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH FYVSEHPLEKLRSTISPILSPISLTAIANHINKKVSAVAILTDMRKIFTKANNEPMAFIQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE LEDISGQVEGIVFPRTYQKVEQLLQLDSRVIVWGKVQQKEDRTQLIVDDLEPIEEVRMLM EECCCCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH IRLSPSELHHTQSQQRLKQILSQQAGDKKKRGRIPVIVIVGRGGDRTFIRLGQDYWVEDD HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCH HQALLALRQGGFHVYRENLIPQAQAS HHHHHHHHHCCHHHHHHHCCCCCCCC >Mature Secondary Structure MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANY CHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEHHCCCCCCCEEEEEEEEEEEEEECC PVEYMTALLSASSGNKDKVRKYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQ CHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHCCHHHHHHHHHHH NLGENAINAILAAREAGPFLSLSDLCSRLDLRVVNRRALETLITCGGLDSLHDNRQAMLK HHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHH GLDLMMDWAQLKAKEKASGQTNLFESLGDTAAAFDEAPVLPKVADLTLEEKLRQEKELLG HHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH FYVSEHPLEKLRSTISPILSPISLTAIANHINKKVSAVAILTDMRKIFTKANNEPMAFIQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE LEDISGQVEGIVFPRTYQKVEQLLQLDSRVIVWGKVQQKEDRTQLIVDDLEPIEEVRMLM EECCCCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH IRLSPSELHHTQSQQRLKQILSQQAGDKKKRGRIPVIVIVGRGGDRTFIRLGQDYWVEDD HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCH HQALLALRQGGFHVYRENLIPQAQAS HHHHHHHHHCCHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231; 9689062; 10734038; 11170467 [H]