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The map label for this gene is mtnA [H]

Identifier: 170078903

GI number: 170078903

Start: 2387169

End: 2388311

Strand: Reverse

Name: mtnA [H]

Synonym: SYNPCC7002_A2308

Alternate gene names: 170078903

Gene position: 2388311-2387169 (Counterclockwise)

Preceding gene: 170078905

Following gene: 170078900

Centisome position: 79.4

GC content: 52.84

Gene sequence:

>1143_bases
ATGCAAGGCGATCGCCGGAGAAATTTACCGAATGTATTTTTTTTCGTCCGCCCTCAGGCCACAATAGGGAAGATTTTTCA
CCGTTGGAATTTTCCCAGTTTAATGAGCAACTCCATTAACCCCATCGTTTGGCAAGAAGACTGCGTCCTCCTCGTGGATC
AAACCCTGCTCCCCCTCGCCTATAAAGTCGTCGAAATTAAAACCTACCAGGCCATGGCTGAGGCGATCCGCACGATGATT
GTCCGGGGAGCACCTGCCATCGGGGTTTCGGCGGCCTATGGTCTATACCTGGGGGCAAAGGAGATCCAAACCACAGACCG
CACCATTTTTCTGGAAAAACTAGAGGCAATCGCCGCAACCCTCCGGCAAACCAGACCCACCGCAGTCAATCTCTTTTGGG
CCATTGATCGGGTGATGGCAACGGTGCAAGGGGCGACTGGTAATATTCCTGAGTTGCAAAATTTAATTCTCAATACCGCC
AAGGCGATCCACAATGAAGACCTCGCCACCTGCCAGGCGATCGGTGATCAGGGGTTGGCGGTTCTTCCCGAAACCCCCGA
AAAATTAACGATCCTCACCCATTGTAATGCGGGTGGTTTAGCCACGGCGGGTTATGGCACAGCTTTGGGCGTGATTCGTT
CAGCTTGGCGGGAAAATCGTTTAGGGATGGTCTATGCTGACGAAACTCGACCCCGGCTCCAGGGTTCCAAGCTCACCACC
TGGGAATGTGTTCAGGAAGGGATTCCCGTGACGCAAATTTGTGACAACATGGCCGCCCACTGTATGCAGCAGGGTCGCAT
CGATGCAGTGGTGGTCGGGGCCGACCGGATTACAGCTAATGGCGATGCGGCGAATAAAATTGGCACCTACAGTTTGGCGA
TCGTCGCGAAGGCCCACAATGTTCCTTTTTTCGTGGCGGCTCCTTTATCGACGGTGGATTTTTCCCTCAGTGACGGTAAA
CAAATTCCCATTGAGGAGCGCGATCCTAAGGAAGTTTATCAAATTGGTGACACGCGCATTTGCCCGGAAGGGGTGCAATT
TTATAATCCGGCTTTTGACGTGACCCCGGCCCATCTAATCACGGCGATCATTACAGAAAAAGGGGCCGTGGCTCCCGACC
AGTTGATTCATCTCAAGGGCTAG

Upstream 100 bases:

>100_bases
ATCGTGCATGATGCTCATAAAATCAGCGAATTCACTCATTTTCCCGCTTCTCCAAGCCGTTAGGGGGTTTTAGTTACCTT
ACATGGCCATGGTAGCGGAG

Downstream 100 bases:

>100_bases
AAACCGCCCCCTCTATCCCCTCCCAAGCGGTGAAGATTCAAAATAGCTGGGTCAAAATGGGCAGTAAGCCCAACACACTA
AAGCCCAGCAAAAAATACAA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MQGDRRRNLPNVFFFVRPQATIGKIFHRWNFPSLMSNSINPIVWQEDCVLLVDQTLLPLAYKVVEIKTYQAMAEAIRTMI
VRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAATLRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTA
KAIHNEDLATCQAIGDQGLAVLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTT
WECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHNVPFFVAAPLSTVDFSLSDGK
QIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLITAIITEKGAVAPDQLIHLKG

Sequences:

>Translated_380_residues
MQGDRRRNLPNVFFFVRPQATIGKIFHRWNFPSLMSNSINPIVWQEDCVLLVDQTLLPLAYKVVEIKTYQAMAEAIRTMI
VRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAATLRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTA
KAIHNEDLATCQAIGDQGLAVLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTT
WECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHNVPFFVAAPLSTVDFSLSDGK
QIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLITAIITEKGAVAPDQLIHLKG
>Mature_380_residues
MQGDRRRNLPNVFFFVRPQATIGKIFHRWNFPSLMSNSINPIVWQEDCVLLVDQTLLPLAYKVVEIKTYQAMAEAIRTMI
VRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAATLRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTA
KAIHNEDLATCQAIGDQGLAVLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTT
WECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHNVPFFVAAPLSTVDFSLSDGK
QIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLITAIITEKGAVAPDQLIHLKG

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=354, Percent_Identity=43.7853107344633, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI23943880, Length=345, Percent_Identity=38.5507246376812, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4503503, Length=274, Percent_Identity=27.3722627737226, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657058, Length=186, Percent_Identity=31.7204301075269, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI78000158, Length=173, Percent_Identity=27.1676300578035, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI78000156, Length=173, Percent_Identity=27.1676300578035, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI187607323, Length=173, Percent_Identity=27.1676300578035, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17557462, Length=331, Percent_Identity=37.1601208459215, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17557123, Length=185, Percent_Identity=29.1891891891892, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325375, Length=384, Percent_Identity=34.8958333333333, Blast_Score=198, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21357667, Length=353, Percent_Identity=39.943342776204, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24651647, Length=353, Percent_Identity=39.943342776204, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 41464; Mature: 41464

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGDRRRNLPNVFFFVRPQATIGKIFHRWNFPSLMSNSINPIVWQEDCVLLVDQTLLPLA
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCCCEEECCCCEEEEHHHHHHHH
YKVVEIKTYQAMAEAIRTMIVRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
LRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTAKAIHNEDLATCQAIGDQGLA
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTT
ECCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
WECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHN
HHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCCCEEEEEEEEECC
VPFFVAAPLSTVDFSLSDGKQIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLI
CCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHH
TAIITEKGAVAPDQLIHLKG
HHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MQGDRRRNLPNVFFFVRPQATIGKIFHRWNFPSLMSNSINPIVWQEDCVLLVDQTLLPLA
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCCCEEECCCCEEEEHHHHHHHH
YKVVEIKTYQAMAEAIRTMIVRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHH
LRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTAKAIHNEDLATCQAIGDQGLA
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTT
ECCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
WECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHN
HHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCCCEEEEEEEEECC
VPFFVAAPLSTVDFSLSDGKQIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLI
CCEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHH
TAIITEKGAVAPDQLIHLKG
HHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA